{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T04:55:59Z","timestamp":1781931359327,"version":"3.54.5"},"reference-count":64,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T00:00:00Z","timestamp":1691193600000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005847","name":"Health and Medical Research Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005407","name":"Food and Health Bureau","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005407","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>This network meta-analysis aimed to compare the effects of bariatric surgery, novel glucose-lowering agents (SGLT2i, GLP1RA, DPP4i), and insulin for patients with type 2 diabetes mellitus (T2DM) and obesity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Four databases were searched from inception to April 2023 to identify randomized controlled trials (RCTs) comparing bariatric surgery, SGLT2i, GLP1RA, DPP4i, insulin, and\/or placebo\/usual care among patients with T2DM and obesity in the achievement of HbA1c &amp;lt; 7.0 per cent within one year, and 12-month changes in HbA1c and body weight.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 376 eligible RCTs (149 824 patients) were analysed. Bariatric surgery had significantly higher rates of achieving HbA1c &amp;lt; 7.0 per cent than SGLT2i (RR = 2.46, 95 per cent c.i. = 1.28, 4.92), DPP4i (RR = 2.59, 95 per cent c.i. = 1.36, 5.13), insulin (RR = 2.27, 95 per cent c.i. = 1.18, 4.58) and placebo\/usual care (RR = 4.02, 95 per cent c.i. = 2.13, 7.93), but had no statistically significant difference from GLP1RA (RR = 1.73, 95 per cent c.i. = 0.91, 3.44), regardless of oral (RR = 1.33, 95 per cent c.i. = 0.66, 2.79) or injectable (RR = 1.75, 95 per cent c.i. = 0.92, 3.45) administration. Significantly more GLP1RA patients achieved HbA1c &amp;lt; 7.0 per cent than other non-surgical treatments. Bariatric surgery had the greatest reductions in HbA1c (\u223c1 per cent more) and body weight (\u223c15\u2005kg more) at 12 months. Among novel glucose-lowering medications, GLP1RA was associated with greater reductions in HbA1c than SGLT2i (\u22120.39 per cent, 95 per cent c.i. = \u22120.55, \u22120.22) and DPP4i (\u22120.51 per cent, 95 per cent c.i. = \u22120.64, \u22120.39) at 12 months, while GLP1RA (\u22121.74\u2005kg, 95 per cent c.i. = \u22122.48, \u22121.01) and SGLT2i (\u22122.23\u2005kg, 95 per cent c.i. = \u22123.07, \u22121.39) showed greater reductions in body weight than DPP4i at 12 months.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Bariatric surgery showed superiority in glycaemic control and weight management compared to non-surgical approaches. GLP1RA administered by oral or injectable form demonstrated reduced HbA1c and body weight at 12 months, and was preferable over other non-surgical treatments among patients with T2DM and obesity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>PROSPERO registration no<\/jats:title>\n                  <jats:p>CRD42020201507<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjsopen\/zrad077","type":"journal-article","created":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T13:04:02Z","timestamp":1691240642000},"source":"Crossref","is-referenced-by-count":8,"title":["Bariatric surgery, novel glucose-lowering agents, and insulin for type 2 diabetes and obesity: Bayesian network meta-analysis of randomized controlled trials"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3609-5016","authenticated-orcid":false,"given":"Tingting","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6895-6071","authenticated-orcid":false,"given":"Carlos K H","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"},{"name":"Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"},{"name":"Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Park , New Territories, Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9813-1126","authenticated-orcid":false,"given":"David T W","family":"Lui","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon K H","family":"Wong","sequence":"additional","affiliation":[{"name":"Division of Surgery, Chinese University of Hong Kong Medical Centre , Hong Kong SAR , China"},{"name":"Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7536-8481","authenticated-orcid":false,"given":"Cindy L K","family":"Lam","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1669-4479","authenticated-orcid":false,"given":"Matthew S H","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong , Hong Kong SAR , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3550-1764","authenticated-orcid":false,"given":"David A","family":"McAllister","sequence":"additional","affiliation":[{"name":"Public Health, School of Health and Wellbeing, University of Glasgow , Glasgow , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8228-526X","authenticated-orcid":false,"given":"Richard","family":"Welbourn","sequence":"additional","affiliation":[{"name":"Department of Upper GI and Bariatric Surgery, Musgrove Park Hospital , Taunton , UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5391-4082","authenticated-orcid":false,"given":"John B","family":"Dixon","sequence":"additional","affiliation":[{"name":"Iverson Health Innovation Research Institute, Swinburne University of Technology , Melbourne, VIC , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,8,5]]},"reference":[{"key":"2023080513034735400_zrad077-B1","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0140-6736(14)60460-8","article-title":"Global, regional, and national prevalence of overweight and obesity in children and adults during 1980\u20132013: a systematic analysis for the Global Burden of Disease Study 2013","volume":"384","author":"Ng","year":"2014","journal-title":"Lancet"},{"key":"2023080513034735400_zrad077-B2","article-title":"IDF Diabetes Atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045","volume":"183","author":"Sun","year":"2021","journal-title":"Diabetes Res Clin Pract"},{"key":"2023080513034735400_zrad077-B3","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1210\/jc.2011-0585","article-title":"Obesity and type 2 diabetes: what can be unified and what needs to be individualized?","volume":"96","author":"Eckel","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"2023080513034735400_zrad077-B4","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.jand.2017.03.022","article-title":"Academy of nutrition and dietetics nutrition practice guideline for type 1 and type 2 diabetes in adults: systematic review of evidence for medical nutrition therapy effectiveness and recommendations for integration into the nutrition care process","volume":"117","author":"Franz","year":"2017","journal-title":"J Acad Nutr Diet"},{"key":"2023080513034735400_zrad077-B5","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/j.pec.2015.11.003","article-title":"Diabetes self-management education for adults with type 2 diabetes mellitus: a systematic review of the effect on glycemic control","volume":"99","author":"Chrvala","year":"2016","journal-title":"Patient Educ Couns"},{"key":"2023080513034735400_zrad077-B6","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.2337\/dc14-1630","article-title":"Weight management in type 2 diabetes: current and emerging approaches to treatment","volume":"38","author":"Van Gaal","year":"2015","journal-title":"Diabetes Care"},{"key":"2023080513034735400_zrad077-B7","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1097\/MED.0000000000000095","article-title":"Effects of metformin on weight loss: potential mechanisms","volume":"21","author":"Malin","year":"2014","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"2023080513034735400_zrad077-B8","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1111\/obr.12841","article-title":"Weight loss variability with SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes mellitus and obesity: mechanistic possibilities","volume":"20","author":"Brown","year":"2019","journal-title":"Obes Rev"},{"key":"2023080513034735400_zrad077-B9","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.pcd.2019.01.003","article-title":"Network meta-analysis of nine large cardiovascular outcome trials of new antidiabetic drugs","volume":"13","author":"Alfayez","year":"2019","journal-title":"Prim Care Diabetes"},{"key":"2023080513034735400_zrad077-B10","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1001\/jama.2018.3024","article-title":"Association between use of sodium\u2013glucose cotransporter 2 inhibitors, glucagon-like peptide 1 agonists, and dipeptidyl peptidase 4 inhibitors with all-cause mortality in patients with type 2 diabetes: a systematic review and meta-analysis","volume":"319","author":"Zheng","year":"2018","journal-title":"JAMA"},{"key":"2023080513034735400_zrad077-B11","doi-asserted-by":"crossref","first-page":"S100","DOI":"10.2337\/dc21-S008","article-title":"8. Obesity management for the treatment of type 2 diabetes: standards of medical care in diabetes\u20132021","volume":"44","author":"American Diabetes Association","year":"2021","journal-title":"Diabetes Care"},{"key":"2023080513034735400_zrad077-B12","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1001\/jamasurg.2013.3654","article-title":"The effectiveness and risks of bariatric surgery: an updated systematic review and meta-analysis, 2003\u20132012","volume":"149","author":"Chang","year":"2014","journal-title":"JAMA Surg"},{"key":"2023080513034735400_zrad077-B13","doi-asserted-by":"crossref","first-page":"f5934","DOI":"10.1136\/bmj.f5934","article-title":"Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials","volume":"347","author":"Gloy","year":"2013","journal-title":"BMJ"},{"key":"2023080513034735400_zrad077-B14","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s12933-018-0722-z","article-title":"Comparative cardiovascular outcomes in the era of novel anti-diabetic agents: a comprehensive network meta-analysis of 166,371 participants from 170 randomized controlled trials","volume":"17","author":"Zhuang","year":"2018","journal-title":"Cardiovasc Diabetol"},{"key":"2023080513034735400_zrad077-B15","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.diabres.2013.04.005","article-title":"Effect of laparoscopic Roux-en-Y gastric bypass surgery on type 2 diabetes mellitus with hypertension: a randomized controlled trial","volume":"101","author":"Liang","year":"2013","journal-title":"Diabetes Res Clin Pract"},{"key":"2023080513034735400_zrad077-B16","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s11695-013-1114-9","article-title":"Efficacy of laparoscopic sleeve gastrectomy and intensive medical management in obese patients with type 2 diabetes mellitus","volume":"24","author":"Palikhe","year":"2014","journal-title":"Obes Surg"},{"key":"2023080513034735400_zrad077-B17","doi-asserted-by":"crossref","first-page":"3267","DOI":"10.1007\/s11695-017-2770-y","article-title":"Surgical and advanced medical therapy for the treatment of type 2 diabetes in class I obese patients: a short-term outcome","volume":"27","author":"Bhandari","year":"2017","journal-title":"Obes Surg"},{"key":"2023080513034735400_zrad077-B18","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1007\/s11695-012-0632-1","article-title":"Remission of insulin resistance in type 2 diabetic patients after gastric bypass surgery or exenatide therapy","volume":"22","author":"Yong","year":"2012","journal-title":"Obes Surg"},{"key":"2023080513034735400_zrad077-B19","doi-asserted-by":"crossref","first-page":"777","DOI":"10.7326\/M14-2385","article-title":"The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations","volume":"162","author":"Hutton","year":"2015","journal-title":"Ann Intern Med"},{"key":"2023080513034735400_zrad077-B20","doi-asserted-by":"crossref","first-page":"d5928","DOI":"10.1136\/bmj.d5928","article-title":"The Cochrane Collaboration's tool for assessing risk of bias in randomised trials","volume":"343","author":"Higgins","year":"2011","journal-title":"BMJ"},{"key":"2023080513034735400_zrad077-B21","article-title":"Metan\u2014an alternative meta-analysis command","volume":"8","author":"Bradburn","year":"1999","journal-title":"Stata Tech Bull"},{"key":"2023080513034735400_zrad077-B22","article-title":"Anti-vascular endothelial growth factor for diabetic macular oedema: a network meta-analysis","volume":"10","author":"Virgili","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"2023080513034735400_zrad077-B23","article-title":"Psychological interventions for chronic, non-specific low back pain: systematic review with network meta-analysis","volume":"376","author":"Ho","year":"2022","journal-title":"BMJ"},{"key":"2023080513034735400_zrad077-B24","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-010247","article-title":"Plea for routinely presenting prediction intervals in meta-analysis","volume":"6","author":"IntHout","year":"2016","journal-title":"BMJ Open"},{"key":"2023080513034735400_zrad077-B25","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s13643-017-0473-z","article-title":"Approaches to interpreting and choosing the best treatments in network meta-analyses","volume":"6","author":"Mbuagbaw","year":"2017","journal-title":"Syst Rev"},{"key":"2023080513034735400_zrad077-B26","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jclinepi.2010.04.026","article-title":"GRADE Guidelines: 1. Introduction\u2014GRADE evidence profiles and summary of findings tables","volume":"64","author":"Guyatt","year":"2011","journal-title":"J Clin Epidemiol"},{"key":"2023080513034735400_zrad077-B27","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1182\/bloodadvances.2021005666","article-title":"Surgical management of patients with von Willebrand disease: summary of 2 systematic reviews of the literature","volume":"6","author":"Brignardello-Petersen","year":"2022","journal-title":"Blood Adv"},{"key":"2023080513034735400_zrad077-B28","doi-asserted-by":"crossref","first-page":"2262","DOI":"10.2337\/dc19-0898","article-title":"Efficacy, safety, and tolerability of oral semaglutide versus placebo added to insulin with or without metformin in patients with type 2 diabetes: the PIONEER 8 trial","volume":"42","author":"Zinman","year":"2019","journal-title":"Diabetes Care"},{"key":"2023080513034735400_zrad077-B29","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.2337\/dc19-0749","article-title":"PIONEER 1: randomized clinical trial of the efficacy and safety of oral semaglutide monotherapy in comparison with placebo in patients with type 2 diabetes","volume":"42","author":"Aroda","year":"2019","journal-title":"Diabetes Care"},{"key":"2023080513034735400_zrad077-B30","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S2213-8587(19)30194-9","article-title":"Efficacy and safety of oral semaglutide with flexible dose adjustment versus sitagliptin in type 2 diabetes (PIONEER 7): a multicentre, open-label, randomised, phase 3a trial","volume":"7","author":"Pieber","year":"2019","journal-title":"Lancet Diabetes Endocrinol"},{"key":"2023080513034735400_zrad077-B31","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1001\/jama.2019.2942","article-title":"Effect of additional oral semaglutide vs sitagliptin on glycated hemoglobin in adults with type 2 diabetes uncontrolled with metformin alone or with sulfonylurea: the PIONEER 3 randomized clinical trial","volume":"321","author":"Rosenstock","year":"2019","journal-title":"JAMA"},{"key":"2023080513034735400_zrad077-B32","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.2337\/dc19-0883","article-title":"Oral semaglutide versus empagliflozin in patients with type 2 diabetes uncontrolled on metformin: the PIONEER 2 trial","volume":"42","author":"Rodbard","year":"2019","journal-title":"Diabetes Care"},{"key":"2023080513034735400_zrad077-B33","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1001\/jama.2017.14752","article-title":"Effect of oral semaglutide compared with placebo and subcutaneous semaglutide on glycemic control in patients with type 2 diabetes: a randomized clinical trial","volume":"318","author":"Davies","year":"2017","journal-title":"JAMA"},{"key":"2023080513034735400_zrad077-B34","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1002\/dmrr.2818","article-title":"Comparison between SGLT2 inhibitors and DPP4 inhibitors added to insulin therapy in type 2 diabetes: a systematic review with indirect comparison meta-analysis","author":"Min","year":"2017","journal-title":"Diabetes Metab Res Rev"},{"key":"2023080513034735400_zrad077-B35","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/bcp.13807","article-title":"Efficacy of DPP-4 inhibitors, GLP-1 analogues, and SGLT2 inhibitors as add-ons to metformin monotherapy in T2DM patients: a model-based meta-analysis","volume":"85","author":"Inoue","year":"2019","journal-title":"Br J Clin Pharmacol"},{"key":"2023080513034735400_zrad077-B36","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0140-6736(21)01640-8","article-title":"Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials","volume":"399","author":"Shi","year":"2022","journal-title":"Lancet"},{"key":"2023080513034735400_zrad077-B37","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/S0140-6736(21)00377-9","article-title":"Semaglutide and effective weight control","volume":"397","author":"Latini","year":"2021","journal-title":"Lancet"},{"key":"2023080513034735400_zrad077-B38","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2020-001706","article-title":"Superior weight loss with once-weekly semaglutide versus other glucagon-like peptide-1 receptor agonists is independent of gastrointestinal adverse events","volume":"8","author":"Lingvay","year":"2020","journal-title":"BMJ Open Diabetes Res Care"},{"key":"2023080513034735400_zrad077-B39","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.133429","article-title":"Semaglutide lowers body weight in rodents via distributed neural pathways","volume":"5","author":"Gabery","year":"2020","journal-title":"JCI Insight"},{"key":"2023080513034735400_zrad077-B40","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/s12933-020-01071-y","article-title":"SGLT2i: beyond the glucose-lowering effect","volume":"19","author":"Ni","year":"2020","journal-title":"Cardiovasc Diabetol"},{"key":"2023080513034735400_zrad077-B41","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.119.014908","article-title":"Sodium\u2013glucose cotransporter 2 inhibition for the prevention of cardiovascular events in patients with type 2 diabetes mellitus: a systematic review and meta-analysis","volume":"9","author":"Arnott","year":"2020","journal-title":"J Am Heart Assoc"},{"key":"2023080513034735400_zrad077-B42","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/S2213-8587(19)30249-9","article-title":"Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials","volume":"7","author":"Kristensen","year":"2019","journal-title":"The Lancet Diabetes & Endocrinology"},{"key":"2023080513034735400_zrad077-B43","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0111543","article-title":"Efficacy and safety of dipeptidyl peptidase-4 inhibitors in type 2 diabetes mellitus patients with moderate to severe renal impairment: a systematic review and meta-analysis","volume":"9","author":"Cheng","year":"2014","journal-title":"PLoS One"},{"key":"2023080513034735400_zrad077-B44","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.diabres.2019.02.014","article-title":"Meta-analyses of the effects of DPP-4 inhibitors, SGLT2 inhibitors and GLP1 receptor analogues on cardiovascular death, myocardial infarction, stroke and hospitalization for heart failure","volume":"150","author":"Sinha","year":"2019","journal-title":"Diabetes Res Clin Pract"},{"key":"2023080513034735400_zrad077-B45","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1093\/bjs\/znab245","article-title":"Perioperative mortality in bariatric surgery: meta-analysis","volume":"108","author":"Robertson","year":"2021","journal-title":"Br J Surg"},{"key":"2023080513034735400_zrad077-B46","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1111\/dom.12922","article-title":"Short- and long-term mortality after bariatric surgery: a systematic review and meta-analysis","volume":"19","author":"Cardoso","year":"2017","journal-title":"Diabetes Obes Metab"},{"key":"2023080513034735400_zrad077-B47","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1016\/S0140-6736(21)00591-2","article-title":"Association of metabolic\u2013bariatric surgery with long-term survival in adults with and without diabetes: a one-stage meta-analysis of matched cohort and prospective controlled studies with 174772 participants","volume":"397","author":"Syn","year":"2021","journal-title":"Lancet"},{"key":"2023080513034735400_zrad077-B48","doi-asserted-by":"crossref","first-page":"m4573","DOI":"10.1136\/bmj.m4573","article-title":"Sodium\u2013glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials","volume":"372","author":"Palmer","year":"2021","journal-title":"BMJ"},{"key":"2023080513034735400_zrad077-B49","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.645507","article-title":"Clinical perspectives on the use of subcutaneous and oral formulations of semaglutide","volume":"12","author":"Gallwitz","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"key":"2023080513034735400_zrad077-B50","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1080\/13696998.2020.1722678","article-title":"Oral semaglutide versus injectable glucagon-like peptide-1 receptor agonists: a cost of control analysis","volume":"23","author":"Hansen","year":"2020","journal-title":"J Med Econ"},{"key":"2023080513034735400_zrad077-B51","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1007\/s13300-021-01034-w","article-title":"Once-daily oral semaglutide versus injectable GLP-1 RAs in people with type 2 diabetes inadequately controlled on basal insulin: systematic review and network meta-analysis","volume":"12","author":"Chubb","year":"2021","journal-title":"Diabetes Ther"},{"key":"2023080513034735400_zrad077-B52","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1210\/clinem\/dgaa006","article-title":"Bariatric surgery vs. lifestyle intervention for diabetes treatment: five year outcomes from a randomized trial","volume":"105","author":"Courcoulas","year":"2020","journal-title":"J Clin Endocrinol Metabol"},{"key":"2023080513034735400_zrad077-B53","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/S0140-6736(15)00075-6","article-title":"Bariatric-metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial","volume":"386","author":"Mingrone","year":"2015","journal-title":"Lancet"},{"key":"2023080513034735400_zrad077-B54","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1056\/NEJMoa1600869","article-title":"Bariatric surgery versus intensive medical therapy for diabetes\u20145-year outcomes","volume":"376","author":"Schauer","year":"2017","journal-title":"N Engl J Med"},{"key":"2023080513034735400_zrad077-B55","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1097\/SLA.0000000000000919","article-title":"Randomized pilot trial of bariatric surgery versus intensive medical weight management on diabetes remission in type 2 diabetic patients who do NOT meet NIH criteria for surgery and the role of soluble RAGE as a novel biomarker of success","volume":"260","author":"Parikh","year":"2014","journal-title":"Ann Surg"},{"key":"2023080513034735400_zrad077-B56","doi-asserted-by":"crossref","first-page":"3012","DOI":"10.1007\/s11695-018-3239-3","article-title":"A prospective randomized controlled trial of the metabolic effects of sleeve gastrectomy with transit bipartition","volume":"28","author":"Azevedo","year":"2018","journal-title":"Obes Surg"},{"key":"2023080513034735400_zrad077-B57","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1001\/jamasurg.2014.467","article-title":"Surgical vs medical treatments for type 2 diabetes mellitus: a randomized clinical trial","volume":"149","author":"Courcoulas","year":"2014","journal-title":"JAMA Surg"},{"key":"2023080513034735400_zrad077-B58","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1001\/jamasurg.2015.1534","article-title":"Three-year outcomes of bariatric surgery vs lifestyle intervention for type 2 diabetes mellitus treatment: a randomized clinical trial","volume":"150","author":"Courcoulas","year":"2015","journal-title":"JAMA Surg"},{"key":"2023080513034735400_zrad077-B59","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1056\/NEJMoa1200111","article-title":"Bariatric surgery versus conventional medical therapy for type 2 diabetes","volume":"366","author":"Mingrone","year":"2012","journal-title":"N Engl J Med"},{"key":"2023080513034735400_zrad077-B60","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1056\/NEJMoa1401329","article-title":"Bariatric surgery versus intensive medical therapy for diabetes\u20143-year outcomes","volume":"370","author":"Schauer","year":"2014","journal-title":"N Engl J Med"},{"key":"2023080513034735400_zrad077-B61","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1056\/NEJMoa1200225","article-title":"Bariatric surgery versus intensive medical therapy in obese patients with diabetes","volume":"366","author":"Schauer","year":"2012","journal-title":"N Engl J Med"},{"key":"2023080513034735400_zrad077-B62","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.amjmed.2016.07.019","article-title":"Physical activity in obese type 2 diabetes after gastric bypass or medical management","volume":"130","author":"Panosian","year":"2017","journal-title":"Am J Med"},{"key":"2023080513034735400_zrad077-B63","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/obr.12647","article-title":"Early major complications after bariatric surgery in the USA, 2003\u20132014: a systematic review and meta-analysis","volume":"19","author":"Chang","year":"2018","journal-title":"Obes Rev"},{"key":"2023080513034735400_zrad077-B64","doi-asserted-by":"crossref","first-page":"k4365","DOI":"10.1136\/bmj.k4365","article-title":"Sodium glucose cotransporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study","volume":"363","author":"Ueda","year":"2018","journal-title":"BMJ"}],"container-title":["BJS Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjsopen\/article-pdf\/7\/4\/zrad077\/51043678\/zrad077.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjsopen\/article-pdf\/7\/4\/zrad077\/51043678\/zrad077.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,5]],"date-time":"2023-08-05T13:04:47Z","timestamp":1691240687000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjsopen\/article\/doi\/10.1093\/bjsopen\/zrad077\/7237723"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,10]]},"references-count":64,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,7,10]]}},"URL":"https:\/\/doi.org\/10.1093\/bjsopen\/zrad077","relation":{},"ISSN":["2474-9842"],"issn-type":[{"value":"2474-9842","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,8]]},"published":{"date-parts":[[2023,7,10]]},"article-number":"zrad077"}}