{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T03:58:32Z","timestamp":1774497512019,"version":"3.50.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"vor","delay-in-days":36,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Parathyroid surgery is an appropriate alternative for renal hyperparathyroidism (rHPT) in patients in whom medical therapy fails. European morbidity and outcome data for clearly defined cohorts, potentially reflecting contemporary clinical practice, remain scarce.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Method<\/jats:title>\n                  <jats:p>Data were extracted from the EUROCRINE\u00ae database on all operations for secondary rHPT between 1 January 2015 and 31 December 2021. Multivariable logistic regression analysis was used to identify risk factors for complications. Subgroup analyses were conducted for the two major surgical approaches (subtotal parathyroidectomy or total thyroidectomy with parathyroid transplantation), as well as for redo and concomitant thyroid surgery. The primary outcome was 30-day morbidity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>After excluding 324 patients, data were analysed for 1165 patients, who underwent primary surgery (859), redo surgery (135), or parathyroid surgery with concomitant (planned or unplanned) thyroid surgery (171). The postoperative complication rate was 13.8% (161 patients). Reintervention for bleeding was necessary in 22 patients (1.9%). The length of hospital stay was &amp;gt;1 week in 108 patients (9.8%), and was shorter in the redo parathyroidectomy than first-time parathyroidectomy group (52.0% (66) versus 36.6% (299) discharged within 2 days, respectively). No risk factors for complications could be identified in either the overall or subgroup analyses. In the case of redo surgery or primary surgery with concomitant thyroid surgery, recurrent laryngeal nerve palsy (6.7 versus 3.5%, respectively), revision surgery for bleeding (2.2 versus 1.2%, respectively), and wound infection rates (0.7 versus 0.0%, respectively) remained low.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>This large European multicentre cohort study demonstrates the safety and low morbidity of parathyroid surgery for rHPT.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bjsopen\/zraf048","type":"journal-article","created":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T09:47:27Z","timestamp":1749721647000},"source":"Crossref","is-referenced-by-count":2,"title":["Perioperative characteristics and short-term morbidity after surgery for renal hyperparathyroidism: multicentre EUROCRINE\u00ae registry study"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3642-9514","authenticated-orcid":false,"given":"Klaas","family":"Van Den Heede","sequence":"first","affiliation":[{"name":"Department of General and Endocrine Surgery, Onze\u2013Lieve\u2013Vrouw Hospital Aalst\u2013Asse\u2013Ninove , Aalst ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0137-447X","authenticated-orcid":false,"given":"Nele","family":"Brusselaers","sequence":"additional","affiliation":[{"name":"Department of Women\u2019s and Children\u2019s Health, Karolinska Institute, Karolinska Hospital , Stockholm ,","place":["Sweden"]},{"name":"Global Health Institute, University of Antwerp , Wilrijk ,","place":["Belgium"]},{"name":"Department of Public Health and Primary Care, University Hospital Ghent , Ghent ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0953-1188","authenticated-orcid":false,"given":"Martin","family":"Almquist","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sk\u00e5ne University Hospital , Lund ,","place":["Sweden"]},{"name":"Department of Clinical Sciences, Lund University , Lund ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Riss","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Division of Visceral Surgery, Section of Endocrine Surgery, University of Vienna , Vienna ,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1259-2491","authenticated-orcid":false,"given":"Marco","family":"Raffaelli","sequence":"additional","affiliation":[{"name":"L'Unit\u00e0 Operativa di Chirurgia Endocrina e Metabolica, Fondazione Policlinico Universitario A. Gemelli IRCCS , Rome ,","place":["Italy"]},{"name":"Centro di Ricerca in Chirurgia delle Ghiandole Endocrine e dell\u2019Obesit\u00e0, Universit\u00e0 Cattolica del Sacro Cuore , Rome ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Van Slycke","sequence":"additional","affiliation":[{"name":"Department of General and Endocrine Surgery, Onze\u2013Lieve\u2013Vrouw Hospital Aalst\u2013Asse\u2013Ninove , Aalst ,","place":["Belgium"]},{"name":"Global Health Institute, University of Antwerp , Wilrijk ,","place":["Belgium"]},{"name":"Department of General Surgery, AZ Damiaan Ostende , Ostend ,","place":["Belgium"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,6,12]]},"reference":[{"key":"2025061205472326900_zraf048-B1","doi-asserted-by":"crossref","first-page":"e0158765","DOI":"10.1371\/journal.pone.0158765","article-title":"Global prevalence of chronic kidney disease\u2014a 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