{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T13:34:43Z","timestamp":1783604083854,"version":"3.55.0"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"vor","delay-in-days":5,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010108","name":"Zhongshan Hospital","doi-asserted-by":"publisher","award":["2023ZSCX21"],"award-info":[{"award-number":["2023ZSCX21"]}],"id":[{"id":"10.13039\/501100010108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82473459"],"award-info":[{"award-number":["82473459"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82303443"],"award-info":[{"award-number":["82303443"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273382"],"award-info":[{"award-number":["82273382"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272929"],"award-info":[{"award-number":["82272929"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Program of Shanghai Academic\/Technology Research Leader","doi-asserted-by":"publisher","award":["23XD1400600"],"award-info":[{"award-number":["23XD1400600"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Program of Shanghai Academic\/Technology Research Leader","doi-asserted-by":"publisher","award":["24SF1900300"],"award-info":[{"award-number":["24SF1900300"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Program of Shanghai Academic\/Technology Research Leader","doi-asserted-by":"publisher","award":["20244Y0023"],"award-info":[{"award-number":["20244Y0023"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Program of Shanghai Academic\/Technology Research Leader","doi-asserted-by":"publisher","award":["201940019"],"award-info":[{"award-number":["201940019"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Program of Shanghai Academic\/Technology Research Leader","doi-asserted-by":"publisher","award":["24PJD012"],"award-info":[{"award-number":["24PJD012"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012247","name":"Program of Shanghai Academic\/Technology Research Leader","doi-asserted-by":"publisher","award":["SACA-CY24B09"],"award-info":[{"award-number":["SACA-CY24B09"]}],"id":[{"id":"10.13039\/501100012247","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018904","name":"Beijing Xisike Clinical Oncology Research Foundation","doi-asserted-by":"publisher","award":["Y-2022METAZQN-0003"],"award-info":[{"award-number":["Y-2022METAZQN-0003"]}],"id":[{"id":"10.13039\/100018904","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018904","name":"Beijing Xisike Clinical Oncology Research Foundation","doi-asserted-by":"publisher","award":["Y-Gilead2024-PT-0002"],"award-info":[{"award-number":["Y-Gilead2024-PT-0002"]}],"id":[{"id":"10.13039\/100018904","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018904","name":"Beijing Xisike Clinical Oncology Research Foundation","doi-asserted-by":"publisher","award":["Y-HR2022MS-0251"],"award-info":[{"award-number":["Y-HR2022MS-0251"]}],"id":[{"id":"10.13039\/100018904","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018904","name":"Beijing Xisike Clinical Oncology Research Foundation","doi-asserted-by":"publisher","award":["Y-HR2022QN-0085"],"award-info":[{"award-number":["Y-HR2022QN-0085"]}],"id":[{"id":"10.13039\/100018904","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018904","name":"Beijing Xisike Clinical Oncology Research Foundation","doi-asserted-by":"publisher","award":["ZSLCYJ202329"],"award-info":[{"award-number":["ZSLCYJ202329"]}],"id":[{"id":"10.13039\/100018904","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018904","name":"Beijing Xisike Clinical Oncology Research Foundation","doi-asserted-by":"publisher","award":["202305AF150148"],"award-info":[{"award-number":["202305AF150148"]}],"id":[{"id":"10.13039\/100018904","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>According to a retrospective study at Zhongshan Hospital, external drainage of the main pancreatic duct (MPD) and common bile duct (CBD) is potentially superior over internal drainage. As yet there is no consensus regarding the optimal drainage strategy, and previous studies have not adequately addressed risk stratification for postoperative pancreatic fistula (POPF). The aim of this study is to determine the clinical advantage of external drainage of the MPD and CBD over internal drainage during pancreatoduodenectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multicentre randomized clinical superiority study is designed to compare the effects of external and internal drainage of the MPD and CBD on the incidence of postoperative complications for patients at intermediate or high risk of POPF. In all, 322 eligible patients will be recruited across six pancreatic centres and randomly assigned 1 : 1 to either an external or internal drainage group. The primary outcome is the incidence of clinically relevant POPF (Grade B\/C) within 90 days after surgery. The anticipated duration of enrolment is 1 year, along with a minimum follow-up period of 2 years, with follow-up visits every 3 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This trial will provide evidence for the efficacy of simultaneous external drainage of the MPD and CBD in the management of pancreatoduodenectomy, optimizing drainage strategies for pancreatoduodenectomy and facilitating the adoption of advanced drainage technologies. Registration number: NCT06322680 (http:\/\/www.clinicaltrials.gov); ChiCTR2400086321 (https:\/\/www.chictr.org.cn).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bjsopen\/zraf130","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T11:28:19Z","timestamp":1757935699000},"source":"Crossref","is-referenced-by-count":1,"title":["Impact of external drainage of the main pancreatic duct and common bile duct on postoperative pancreatic fistula following pancreatoduodenectomy: protocol for a multicentre randomized clinical trial"],"prefix":"10.1093","volume":"9","author":[{"given":"Wen-Quan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao-Lin","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin-Hui","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Yi","family":"He","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue-Ming","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Gan","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-Xiang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Chuan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen-Ye","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, First People\u2019s Hospital of Yunnan Province , Kunming 650032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chong-Yi","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Hepato-Biliary-Pancreatic Surgery, Huadong Hospital Affiliated to Fudan University , Shanghai 200040 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi\u2019an Jiaotong University , Xi\u2019an 710061 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"He","sequence":"additional","affiliation":[{"name":"Department of Biliary-Pancreatic Surgery, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital , Shanghai 200001 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu-An","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Dong","family":"Qiu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital , Nanjing 210008 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pancreatic Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Cancer Center, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]},{"name":"Department of General Surgery, Zhongshan Hospital, Fudan University , Shanghai 200032 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,11,4]]},"reference":[{"key":"2025110506170946000_zraf130-B1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1053\/j.seminoncol.2014.12.009","article-title":"Surgical management of pancreatic cancer\u2014pancreaticoduodenectomy","volume":"42","author":"Donahue","year":"2015","journal-title":"Semin Oncol"},{"key":"2025110506170946000_zraf130-B2","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.hbpd.2022.04.006","article-title":"Complications of modern pancreaticoduodenectomy: a systematic review and meta-analysis","volume":"21","author":"Kokkinakis","year":"2022","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"2025110506170946000_zraf130-B3","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1097\/SLA.0000000000001437","article-title":"Effect of hospital volume on surgical outcomes after pancreaticoduodenectomy: a systematic review and meta-analysis","volume":"263","author":"Hata","year":"2016","journal-title":"Ann Surg"},{"key":"2025110506170946000_zraf130-B4","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.ijsu.2018.01.041","article-title":"The outcomes and complications of pancreaticoduodenectomy (Whipple procedure): cross sectional study","volume":"52","author":"Karim","year":"2018","journal-title":"Int J Surg"},{"key":"2025110506170946000_zraf130-B5","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/SLA.0b013e3181492c28","article-title":"External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trial","volume":"246","author":"Poon","year":"2007","journal-title":"Ann Surg"},{"key":"2025110506170946000_zraf130-B6","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/s00534-011-0430-5","article-title":"Use of pancreatic duct stents after pancreaticoduodenectomy","volume":"18","author":"Schulick","year":"2011","journal-title":"J Hepato-Biliary-Pancreat Sci"},{"key":"2025110506170946000_zraf130-B7","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1097\/SLA.0b013e31821219af","article-title":"External pancreatic duct stent decreases pancreatic fistula rate after pancreaticoduodenectomy: prospective multicenter randomized trial","volume":"253","author":"Pessaux","year":"2011","journal-title":"Ann Surg"},{"key":"2025110506170946000_zraf130-B8","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1002\/bjs.10160","article-title":"Randomized multicentre trial comparing external and internal pancreatic stenting during pancreaticoduodenectomy","volume":"103","author":"Jang","year":"2016","journal-title":"Br J Surg"},{"key":"2025110506170946000_zraf130-B9","first-page":"277","article-title":"Internal compared with external drainage of pancreatic duct during pancreaticoduodenectomy: a retrospective study","volume":"26","author":"Meng","year":"2014","journal-title":"Chin J Cancer Res"},{"key":"2025110506170946000_zraf130-B10","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1080\/08941939.2019.1691687","article-title":"The prognostic value of external vs internal pancreatic duct stents in CR-POPF after pancreaticoduodenectomy: a systematic review and meta-analysis","volume":"34","author":"Jiang","year":"2021","journal-title":"J Investig Surg"},{"key":"2025110506170946000_zraf130-B11","doi-asserted-by":"crossref","first-page":"106707","DOI":"10.1016\/j.ijsu.2022.106707","article-title":"Does pancreatic duct stent placement lead to decreased postoperative pancreatic fistula rates after pancreaticoduodenectomy? A meta-analysis","volume":"103","author":"Guo","year":"2022","journal-title":"Int J Surg"},{"key":"2025110506170946000_zraf130-B12","doi-asserted-by":"crossref","first-page":"231","DOI":"10.14701\/kjhbps.2011.15.4.231","article-title":"Effectiveness of external drainage of the bile duct in pancreaticoduodenectomy: a single surgeon\u2019s experience","volume":"15","author":"Yoon","year":"2011","journal-title":"Korean J Hepatobiliary Pancreat Surg"},{"key":"2025110506170946000_zraf130-B13","first-page":"2119","article-title":"Retrospective evaluation of the clinical necessity of external biliary drainage after pancreaticoduodenectomy","volume":"60","author":"Imai","year":"2013","journal-title":"Hepatogastroenterology"},{"key":"2025110506170946000_zraf130-B14","first-page":"330","article-title":"T-Tube biliary drainage during reconstruction after pancreaticoduodenectomy. A single-center experience","volume":"88","author":"Cianci","year":"2017","journal-title":"Ann Ital Chir"},{"key":"2025110506170946000_zraf130-B15","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/SLA.0000000000002620","article-title":"Alternative Fistula Risk Score for pancreatoduodenectomy (a-FRS): design and international external validation","volume":"269","author":"Mungroop","year":"2019","journal-title":"Ann Surg"},{"key":"2025110506170946000_zraf130-B16"},{"key":"2025110506170946000_zraf130-B17","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.surg.2016.11.014","article-title":"The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 years after","volume":"161","author":"Bassi","year":"2017","journal-title":"Surgery"},{"key":"2025110506170946000_zraf130-B18","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.surg.2010.12.002","article-title":"Bile leakage after hepatobiliary and pancreatic surgery: a definition and grading of severity by the International Study Group of Liver Surgery","volume":"149","author":"Koch","year":"2011","journal-title":"Surgery"},{"key":"2025110506170946000_zraf130-B19","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.surg.2016.06.058","article-title":"Definition and classification of chyle leak after pancreatic operation: a consensus statement by the International Study Group on Pancreatic Surgery","volume":"161","author":"Besselink","year":"2017","journal-title":"Surgery"},{"key":"2025110506170946000_zraf130-B20","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/j.surg.2007.05.005","article-title":"Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"2025110506170946000_zraf130-B21","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.surg.2007.02.001","article-title":"Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition","volume":"142","author":"Wente","year":"2007","journal-title":"Surgery"},{"key":"2025110506170946000_zraf130-B22","first-page":"1","article-title":"The guideline for prevention and treatment of common complications after pancreatic surgery (2022)","volume":"61","year":"2023","journal-title":"Zhonghua Wai Ke Za Zhi"},{"key":"2025110506170946000_zraf130-B23","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1097\/SLA.0000000000005226","article-title":"Postpancreatectomy acute pancreatitis (PPAP): definition and grading from the International Study Group for Pancreatic Surgery (ISGPS)","volume":"275","author":"Marchegiani","year":"2022","journal-title":"Ann Surg"},{"key":"2025110506170946000_zraf130-B24"},{"key":"2025110506170946000_zraf130-B25"},{"key":"2025110506170946000_zraf130-B26","first-page":"CD008914","article-title":"Stents for the prevention of pancreatic fistula following pancreaticoduodenectomy","volume":"2016","author":"Dong","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"key":"2025110506170946000_zraf130-B27","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.ijsu.2019.12.003","article-title":"Critical appraisal of the techniques of pancreatic anastomosis following pancreaticoduodenectomy: a network meta-analysis","volume":"73","author":"Ratnayake","year":"2020","journal-title":"Int J Surg Lond Engl"},{"key":"2025110506170946000_zraf130-B28","doi-asserted-by":"crossref","first-page":"2014","DOI":"10.1056\/NEJMoa1313688","article-title":"Pasireotide for postoperative pancreatic fistula","volume":"370","author":"Allen","year":"2014","journal-title":"N Engl J Med"},{"key":"2025110506170946000_zraf130-B29","doi-asserted-by":"crossref","first-page":"1367238","DOI":"10.1155\/2017\/1367238","article-title":"Are internal or external pancreatic duct stents the preferred choice for patients undergoing pancreaticoduodenectomy? A meta-analysis","volume":"2017","author":"Zhao","year":"2017","journal-title":"BioMed Res Int"},{"key":"2025110506170946000_zraf130-B30","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.hpb.2020.10.025","article-title":"Pros and pitfalls of externalized trans-anastomotic stent as a mitigation strategy of POPF: a prospective risk-stratified observational series","volume":"23","author":"Andrianello","year":"2021","journal-title":"HPB (Oxford)"},{"key":"2025110506170946000_zraf130-B31","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s12893-021-01074-w","article-title":"The prognostic value of external vs internal pancreatic duct stents after pancreaticoduodenectomy in patients with FRS \u2265 4: a retrospective cohort study","volume":"21","author":"Jiang","year":"2021","journal-title":"BMC Surg"}],"container-title":["BJS Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjsopen\/article-pdf\/9\/6\/zraf130\/65174123\/zraf130.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjsopen\/article-pdf\/9\/6\/zraf130\/65174123\/zraf130.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T11:17:17Z","timestamp":1762341437000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjsopen\/article\/doi\/10.1093\/bjsopen\/zraf130\/8314086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,30]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,10,30]]}},"URL":"https:\/\/doi.org\/10.1093\/bjsopen\/zraf130","relation":{},"ISSN":["2474-9842"],"issn-type":[{"value":"2474-9842","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,12]]},"published":{"date-parts":[[2025,10,30]]},"article-number":"zraf130"}}