{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:04:05Z","timestamp":1777874645714,"version":"3.51.4"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"vor","delay-in-days":41,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"AEG Young Talent Group Grant\u20142021"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Symptomatic gallstone disease is a common and burdensome condition, with early cholecystectomy recommended to prevent relapses. However, delayed cholecystectomies lack standardized prioritization criteria. This study aimed to identify determinants independently associated with shorter waiting times for delayed cholecystectomy, and to assess the alignment of current surgical prioritization with relapse predictors described in the previous RELAPSTONE study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a post hoc analysis of the Spanish RELAPSTONE cohort, comprising patients admitted for a first episode of symptomatic gallstone disease between January 2018 and April 2020, who did not undergo cholecystectomy during the index hospital admission. The primary outcome was waiting time (in months) to delayed cholecystectomy. Linear regression models with \u03b2-coefficients were used to identify clinical factors associated with surgical delays (primary outcome of interest). Secondarily, the impact of relapse on prioritization was also evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This study analysed 1508 patients of the 3016 included in the RELAPSTONE cohort. Median age was 68.2 (interquartile range 53.9\u201376.6) years; 51.4% were men. Median waiting time to delayed cholecystectomy was 4.5 (interquartile range 2.3\u20137.0) months. Initial presentation as acute cholecystitis (\u03b2 = \u22122.2, P = 0.048) and multiple cholelithiasis (\u03b2 = \u22120.6, P = 0.006) were linked to shorter waiting times, whereas older age (&amp;gt; 54 years; \u03b2 = 0.8, P = 0.002), advanced liver disease (\u03b2 = 2.4, P = 0.047), and relapse (\u03b2 = 0.5, P = 0.036) were associated with longer delays, compared with their respective reference groups. Among 575 patients (38.1%) with relapse, time to delayed cholecystectomy did not differ by relapse type. Several known risk factors for relapse identified in previous RELAPSTONE analyses, including the performance of endoscopic sphincterotomy and leucocyte and alanine aminotransferase levels, did not influence prioritization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Determinants of surgical timing were not well aligned with previously identified predictors of relapse. These findings support the need for evidence-based triage strategies to improve timing and outcomes of delayed cholecystectomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bjsopen\/zrag021","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T12:55:49Z","timestamp":1771505749000},"source":"Crossref","is-referenced-by-count":0,"title":["Waiting for cholecystectomy: determinants of prioritization for delayed cholecystectomy in a universal public healthcare system\u2014\n                    <i>post hoc<\/i>\n                    analysis of RELAPSTONE cohort (WAIT-CHOL study)"],"prefix":"10.1093","volume":"10","author":[{"given":"Ra\u00fal","family":"Velamaz\u00e1n","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Hospital Cl\u00ednico Universitario Lozano Blesa , Zaragoza ,","place":["Spain"]},{"name":"IIS (Instituto de Investigacion Sanitaria) Arag\u00f3n , Zaragoza ,","place":["Spain"]},{"name":"Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBERehd) Instituto de Salud Carlos III , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Oy\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital General Universitario Gregorio Mara\u00f1\u00f3n , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Lerma-Irureta","sequence":"additional","affiliation":[{"name":"IIS (Instituto de Investigacion Sanitaria) Arag\u00f3n , Zaragoza ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"L\u00f3pez-Guill\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario de Torrevieja , Alicante ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel J","family":"Mart\u00ednez-Dom\u00ednguez","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Cl\u00ednico Universitario Lozano Blesa , Zaragoza ,","place":["Spain"]},{"name":"IIS (Instituto de Investigacion Sanitaria) Arag\u00f3n , Zaragoza ,","place":["Spain"]},{"name":"Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBERehd) Instituto de Salud Carlos III , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Arnau","sequence":"additional","affiliation":[{"name":"Research and Innovation Unit, Althaia Xarxa Assistencial Universit\u00e0ria de Manresa , Manresa ,","place":["Spain"]},{"name":"Central Catalonia Chronicity Research Group (C3RG), Centre for Health and Social Care Research (CESS), University of Vic-Central University of Catalonia (UVIC-UCC) , Vic ,","place":["Spain"]},{"name":"Faculty of Medicine, University of Vic-Central University of Catalonia (UVIC-UCC) , Vic ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Abad Baroja","sequence":"additional","affiliation":[{"name":"IIS (Instituto de Investigacion Sanitaria) Arag\u00f3n , Zaragoza ,","place":["Spain"]},{"name":"Department of Gastroenterology, Hospital Universitario Miguel Servet , Zaragoza ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lara M","family":"Ruiz-Belmonte","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Cl\u00ednico Universitario Lozano Blesa , Zaragoza ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Tejedor-Tejada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario R\u00edo Hortega , Valladolid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raul","family":"Zapater","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Hospital Universitario Ram\u00f3n y Cajal , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noelia","family":"Mart\u00edn-Vicente","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital de Galdakao , Bizkaia ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Jos\u00e9","family":"Fern\u00e1ndez-Esparcia","sequence":"additional","affiliation":[{"name":"Miguel Hernandez University , Elche ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Bel\u00e9n","family":"Juli\u00e1n Gomara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario Miguel Servet , Zaragoza ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Violeta","family":"Sastre Lozano","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario Santa Lucia , Cartagena ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Jos\u00e9","family":"Manzanares Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario Santa Lucia , Cartagena ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Chivato Mart\u00edn-Falquina","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario de Burgos , Burgos ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura Andr\u00e9s","family":"Pascual","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario de Burgos , Burgos ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuria","family":"Torres Monclus","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario Arnau de Vilanova , Lleida ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natividad","family":"Zaragoza Velasco","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario Arnau de Vilanova , Lleida ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3706-8266","authenticated-orcid":false,"given":"Eukene","family":"Rojo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario de La Princesa , Madrid ,","place":["Spain"]},{"name":"IIS (Instituto de Investigaci\u00f3n Sanitaria)-Princesa , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Ca\u00f1amares-Orb\u00eds","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital de Galdakao , Bizkaia ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Pardo Grau","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario Josep Trueta , Girona ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"Vaamonde Lorenzo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario Donostia , Donostia ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arantzazu","family":"Izagirre Arostegi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario Donostia , Donostia ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Flores","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital General Universitario Gregorio Mara\u00f1\u00f3n , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arantxa","family":"Diaz Gomez","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital General Universitario Gregorio Mara\u00f1\u00f3n , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Garcia Garcia de Paredes","sequence":"additional","affiliation":[{"name":"Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBERehd) Instituto de Salud Carlos III , Madrid ,","place":["Spain"]},{"name":"Department of Gastroenterology and Hepatology, Hospital Universitario Ram\u00f3n y Cajal , Madrid ,","place":["Spain"]},{"name":"Universidad de Alcal\u00e1 , Madrid ,","place":["Spain"]},{"name":"IRYCIS (Instituto Ram\u00f3n y Cajal de Investigaci\u00f3n Sanitaria) , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berta","family":"Lape\u00f1a-Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Universitario San Pedro , Logro\u00f1o ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Garc\u00eda-Rayado","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Cl\u00ednico Universitario Lozano Blesa , Zaragoza ,","place":["Spain"]},{"name":"IIS (Instituto de Investigacion Sanitaria) Arag\u00f3n , Zaragoza ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Millastre Bocos","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Cl\u00ednico Universitario Lozano Blesa , Zaragoza ,","place":["Spain"]},{"name":"IIS (Instituto de Investigacion Sanitaria) Arag\u00f3n , Zaragoza ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicente","family":"Borrego","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Cl\u00ednico Universitario Lozano Blesa , Zaragoza ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Sostres","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Cl\u00ednico Universitario Lozano Blesa , Zaragoza ,","place":["Spain"]},{"name":"IIS (Instituto de Investigacion Sanitaria) Arag\u00f3n , Zaragoza ,","place":["Spain"]},{"name":"Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBERehd) Instituto de Salud Carlos III , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angel","family":"Lanas","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital Cl\u00ednico Universitario Lozano Blesa , Zaragoza ,","place":["Spain"]},{"name":"IIS (Instituto de Investigacion Sanitaria) Arag\u00f3n , Zaragoza ,","place":["Spain"]},{"name":"Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas (CIBERehd) Instituto de Salud Carlos III , Madrid ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1186-953X","authenticated-orcid":false,"given":"Jose Manuel","family":"Ramia","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital General Universitario Dr Balmis , Alicante ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2412-9541","authenticated-orcid":false,"given":"Enrique","family":"de-Madaria","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hospital General Universitario Dr Balmis-ISABIAL , Alicante ,","place":["Spain"]},{"name":"Department of Clinical Medicine, Miguel Hernandez University , Elche ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,4,15]]},"reference":[{"key":"2026043016081207500_zrag021-B1","doi-asserted-by":"crossref","first-page":"16 024","DOI":"10.1038\/nrdp.2016.24","article-title":"Gallstones","volume":"2","author":"Lammert","year":"2016","journal-title":"Nat Rev Dis Primers"},{"key":"2026043016081207500_zrag021-B2","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.cgh.2022.04.010","article-title":"The natural history of asymptomatic gallstones: a longitudinal study and prediction model","volume":"21","author":"Morris-Stiff","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2026043016081207500_zrag021-B3","first-page":"1","article-title":"Use of national burden to define operative emergency general surgery","volume":"02115","author":"Scott","year":"2016","journal-title":"JAMA Surg"},{"key":"2026043016081207500_zrag021-B4","doi-asserted-by":"crossref","first-page":"419","DOI":"10.14309\/ajg.0000000000002645","article-title":"American College of Gastroenterology guidelines: management of acute pancreatitis","volume":"119","author":"Tenner","year":"2024","journal-title":"Am J Gastroenterol"},{"key":"2026043016081207500_zrag021-B5","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/jhbp.516","article-title":"Tokyo guidelines 2018: flowchart for the management of acute cholecystitis","volume":"25","author":"Okamoto","year":"2018","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"2026043016081207500_zrag021-B6","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.gie.2018.10.001","article-title":"ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis","volume":"89","author":"Buxbaum","year":"2019","journal-title":"Gastrointest Endosc"},{"key":"2026043016081207500_zrag021-B7","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.pan.2025.04.020","article-title":"International Association of Pancreatology revised guidelines on acute pancreatitis 2025: supported and endorsed by the American Pancreatic Association, European Pancreatic Club, Indian Pancreas Club, and Japan Pancreas Society","volume":"25","author":"P\u00e1rniczky","year":"2025","journal-title":"Pancreatology"},{"key":"2026043016081207500_zrag021-B8","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/S0140-6736(15)00274-3","article-title":"Same-admission versus interval cholecystectomy for mild gallstone pancreatitis (PONCHO): a multicentre randomised controlled trial","volume":"386","author":"Da Costa","year":"2015","journal-title":"Lancet"},{"key":"2026043016081207500_zrag021-B9","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1002\/bjs.11221","article-title":"Meta-analysis of randomized clinical trials of early versus delayed cholecystectomy for mild gallstone pancreatitis","volume":"106","author":"Moody","year":"2019","journal-title":"Br J Surg"},{"key":"2026043016081207500_zrag021-B10","year":"2023"},{"key":"2026043016081207500_zrag021-B11","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1097\/SLA.0b013e3182507646","article-title":"Timing of cholecystectomy after mild biliary pancreatitis: a systematic review","volume":"255","author":"Van Baal","year":"2012","journal-title":"Ann Surg"},{"key":"2026043016081207500_zrag021-B12","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1002\/bjs.10287","article-title":"Population-based cohort study of outcomes following cholecystectomy for benign gallbladder diseases","volume":"103","author":"CholeS Study Group, West Midlands Research Collaborative","year":"2014","journal-title":"Br J Surg"},{"key":"2026043016081207500_zrag021-B13","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jamcollsurg.2010.02.053","article-title":"Rationale and use of the critical view of safety in laparoscopic cholecystectomy","volume":"211","author":"Strasberg","year":"2010","journal-title":"J Am Coll Surg"},{"key":"2026043016081207500_zrag021-B14","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/ueg2.12544","article-title":"Symptomatic gallstone disease: recurrence patterns and risk factors for relapse after first admission, the RELAPSTONE study","volume":"12","author":"Velamaz\u00e1n","year":"2024","journal-title":"United Eur Gastroenterol J"},{"key":"2026043016081207500_zrag021-B15","author":"Planells Roig"},{"key":"2026043016081207500_zrag021-B16","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0009-739X(02)72071-X","article-title":"Informe sobre los criterios para establecer prioridades al incluir pacientes en lista de espera de cirug\u00eda","volume":"72","author":"Escribano","year":"2002","journal-title":"Cir Esp"},{"key":"2026043016081207500_zrag021-B17","first-page":"34","article-title":"Factors influencing waiting times for elective laparoscopic cholecystectomy","volume":"50","author":"Lau","year":"2007","journal-title":"Can J Surg"},{"key":"2026043016081207500_zrag021-B18","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1186\/s12893-024-02694-8","article-title":"Emergency cholecystectomy: risk factors and impact of delay on electively booked patients, a 5-year experience of a tertiary care","volume":"24","author":"Alsaleh","year":"2024","journal-title":"BMC Surg"},{"key":"2026043016081207500_zrag021-B19","first-page":"231","article-title":"Priority access criteria for elective cholecystectomy: a comparison of three scoring methods","volume":"111","author":"Dennett","year":"1998","journal-title":"N Z Med J"},{"key":"2026043016081207500_zrag021-B20","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1046\/j.1445-2197.2003.02826.x","article-title":"Elective laparoscopic cholecystectomy: implications of prolonged waiting times for surgery","volume":"73","author":"Awrentschuk","year":"2003","journal-title":"ANZ J Surg"},{"key":"2026043016081207500_zrag021-B21","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1136\/gutjnl-2012-302779","article-title":"Classification of acute pancreatitis\u20142012: revision of the Atlanta classification and definitions by international consensus","volume":"62","author":"Banks","year":"2013","journal-title":"Gut"},{"key":"2026043016081207500_zrag021-B22","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/jhbp.512","article-title":"Tokyo guidelines 2018: diagnostic criteria and severity grading of acute cholangitis (with videos)","volume":"25","author":"Kiriyama","year":"2018","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"2026043016081207500_zrag021-B23","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/jhbp.515","article-title":"Tokyo guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos)","volume":"25","author":"Yokoe","year":"2018","journal-title":"J Hepatobiliary Pancreat Sci"},{"key":"2026043016081207500_zrag021-B24","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","journal-title":"J Clin Epidemiol"},{"key":"2026043016081207500_zrag021-B25","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ciresp.2010.03.045","article-title":"Lesiones iatrog\u00e9nicas de la v\u00eda biliar","volume":"88","author":"Ruiz G\u00f3mez","year":"2010","journal-title":"Cirug\u00eda Espa\u00f1ola"},{"key":"2026043016081207500_zrag021-B26","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1038\/ajg.2012.126","article-title":"Natural history following the first attack of acute pancreatitis","volume":"107","author":"Yadav","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"2026043016081207500_zrag021-B27","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/TA.0b013e3182788e4d","article-title":"A population-based analysis of the clinical course of 10 304 patients with acute cholecystitis, discharged without cholecystectomy","volume":"74","author":"De Mestral","year":"2013","journal-title":"J Trauma Acute Care Surg"},{"key":"2026043016081207500_zrag021-B28","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1016\/j.dld.2025.06.005","article-title":"Lower rate of pancreatobiliary complications after sludge and microlithiasis pancreatitis compared to gallstone pancreatitis","volume":"57","author":"Sirtl","year":"2025","journal-title":"Dig Liver Dis"},{"key":"2026043016081207500_zrag021-B29","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1055\/a-1452-8919","article-title":"Do endosonographers agree on the presence of bile duct sludge and the subsequent need for intervention?","volume":"9","author":"Quispel","year":"2021","journal-title":"Endosc Int Open"},{"key":"2026043016081207500_zrag021-B30","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1007\/s00464-009-0339-0","article-title":"Recurrent acute biliary pancreatitis: the protective role of cholecystectomy and endoscopic sphincterotomy","volume":"23","author":"Van Geenen","year":"2009","journal-title":"Surg Endosc"},{"key":"2026043016081207500_zrag021-B31","first-page":"CD006233","article-title":"Cholecystectomy deferral in patients with endoscopic sphincterotomy","volume":"2007","author":"McAlister","year":"2007","journal-title":"Cochrane Database Syst Rev"}],"container-title":["BJS Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjsopen\/article-pdf\/10\/2\/zrag021\/68083990\/zrag021.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjsopen\/article-pdf\/10\/2\/zrag021\/68083990\/zrag021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T20:08:23Z","timestamp":1777579703000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjsopen\/article\/doi\/10.1093\/bjsopen\/zrag021\/8654149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,5]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3,5]]}},"URL":"https:\/\/doi.org\/10.1093\/bjsopen\/zrag021","relation":{},"ISSN":["2474-9842"],"issn-type":[{"value":"2474-9842","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,4]]},"published":{"date-parts":[[2026,3,5]]},"article-number":"zrag021"}}