{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:04:15Z","timestamp":1777874655007,"version":"3.51.4"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T00:00:00Z","timestamp":1776211200000},"content-version":"vor","delay-in-days":41,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Swedish Heart Lung Foundation","award":["20150890"],"award-info":[{"award-number":["20150890"]}]},{"name":"Region V\u00e4sterbotten"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with sleep apnoea are at increased risk of postoperative cardiac and respiratory complications, but its prevalence in patients undergoing abdominal cancer surgery is poorly defined. The aim of this study was to estimate the prevalence of sleep apnoea in patients undergoing colorectal cancer surgery compared with community-based controls, and to assess the utility of symptoms, signs, and the STOP-Bang questionnaire in identifying sleep apnoea.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective observational study included consecutive patients scheduled for colorectal cancer surgery at Ume\u00e5 University Hospital, Sweden, between 7 January 2015 and 24 May 2020. Overnight polysomnography, including electroencephalogram-based sleep scoring, was undertaken before operation. Prevalence estimates were compared with those of two community-based cohorts from Uppsala, Sweden (female participants from the Sleep and Health in Women cohort; male participants from the Men in Uppsala: A Study of Sleep Apnoea and Cardiometabolic Health cohort). The primary outcome was the prevalence of sleep apnoea.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 268 eligible patients, 5 were receiving continuous positive airway pressure therapy and 201 underwent successful polysomnography. Moderate-to-severe sleep apnoea was identified in 98 of 206 patients (48 (95% confidence interval 41 to 54)%) undergoing colorectal cancer surgery, with a similar prevalence in men and women. Among 597 community-based controls, moderate-to-severe sleep apnoea was present in 27 (24 to 31)%. After adjustment for age, sex, and body mass index, the odds ratio for moderate-to-severe sleep apnoea in patients with colorectal cancer was 1.57 (95% confidence interval 1.08 to 2.29; P = 0.019). The STOP-Bang questionnaire demonstrated acceptable sensitivity (85 (95% confidence interval 76 to 91)%) but low specificity (42 (33 to 52)%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Approximately half of patients undergoing colorectal cancer surgery have moderate-to-severe sleep apnoea, exceeding the prevalence in community-based controls. Clinical symptoms, signs, and STOP-Bang screening are insufficient to reliably identify affected patients, indicating that overnight sleep apnoea assessment is required in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bjsopen\/zrag025","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T12:55:50Z","timestamp":1771505750000},"source":"Crossref","is-referenced-by-count":0,"title":["Sleep apnoea in patients undergoing colorectal cancer surgery: prospective cohort study"],"prefix":"10.1093","volume":"10","author":[{"given":"Martin","family":"Claesson","sequence":"first","affiliation":[{"name":"Department of Diagnostics and Intervention, Surgery, Ume\u00e5 University , Ume\u00e5 ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Lindberg","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University , Uppsala ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carin","family":"Sahlin","sequence":"additional","affiliation":[{"name":"Department of Public Health and Clinical Medicine, Ume\u00e5 University , Ume\u00e5 ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Blomberg","sequence":"additional","affiliation":[{"name":"Department of Public Health and Clinical Medicine, Ume\u00e5 University , Ume\u00e5 ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markku M","family":"Haapam\u00e4ki","sequence":"additional","affiliation":[{"name":"Department of Diagnostics and Intervention, Surgery, Ume\u00e5 University , Ume\u00e5 ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7516-9543","authenticated-orcid":false,"given":"Malin","family":"Sund","sequence":"additional","affiliation":[{"name":"Department of Diagnostics and Intervention, Surgery, Ume\u00e5 University , Ume\u00e5 ,","place":["Sweden"]},{"name":"Department of Surgery, University of Helsinki and Helsinki University Hospital , Helsinki ,","place":["Finland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan","family":"Svensson","sequence":"additional","affiliation":[{"name":"Department of Diagnostics and Intervention, Surgery, Ume\u00e5 University , Ume\u00e5 ,","place":["Sweden"]},{"name":"Department of Statistics, Ume\u00e5 School of Business, Economics and Statistics, Ume\u00e5 University , Ume\u00e5 ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2819-2799","authenticated-orcid":false,"given":"Jenny","family":"Theorell-Hagl\u00f6w","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University , Uppsala ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malin","family":"Jonsson Fagerlund","sequence":"additional","affiliation":[{"name":"Perioperative Medicine and Intensive Care and Department of Physiology and Pharmacology, Karolinska University Hospital and Karolinska Institutet , Stockholm ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5306-1697","authenticated-orcid":false,"given":"Karl A","family":"Franklin","sequence":"additional","affiliation":[{"name":"Department of Diagnostics and Intervention, Surgery, Ume\u00e5 University , Ume\u00e5 ,","place":["Sweden"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,4,15]]},"reference":[{"key":"2026043016084999000_zrag025-B1","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1093\/bja\/aes465","article-title":"Proportion of surgical patients with undiagnosed 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A qualitative systematic review for the Society of Anesthesia and Sleep Medicine Task Force on preoperative preparation of patients with sleep-disordered breathing","volume":"122","author":"Opperer","year":"2016","journal-title":"Anesth Analg"},{"key":"2026043016084999000_zrag025-B8","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1001\/jama.2019.4783","article-title":"Postoperative vascular complications in unrecognized obstructive sleep apnea study I. Association of unrecognized obstructive sleep apnea with postoperative cardiovascular events in patients undergoing major noncardiac surgery","volume":"321","author":"Chan","year":"2019","journal-title":"JAMA"},{"key":"2026043016084999000_zrag025-B9","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1097\/ALN.0000000000000053","article-title":"Practice guidelines for the perioperative management of patients with obstructive sleep apnea","volume":"120","author":"Gross","year":"2014","journal-title":"Anesthesiology"},{"key":"2026043016084999000_zrag025-B10","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1213\/ANE.0000000000001416","article-title":"Society of Anesthesia and Sleep Medicine guidelines on preoperative screening and assessment of adult patients with obstructive sleep apnea","volume":"123","author":"Chung","year":"2016","journal-title":"Anesth Analg"},{"key":"2026043016084999000_zrag025-B11","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1097\/ALN.0b013e31816d83e4","article-title":"STOP questionnaire: a tool to screen patients for obstructive sleep apnea","volume":"108","author":"Chung","year":"2008","journal-title":"Anesthesiology"},{"key":"2026043016084999000_zrag025-B12","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1213\/ANE.0000000000005480","article-title":"Perioperative continuous positive airway pressure therapy: a review with the emphasis on randomized controlled trials and obstructive sleep apnea","volume":"132","author":"Jonsson Fagerlund","year":"2021","journal-title":"Anesth Analg"},{"key":"2026043016084999000_zrag025-B13","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.4158\/GL-2019-0406","article-title":"Clinical practice guidelines for the perioperative nutrition, metabolic, and nonsurgical support of patients undergoing bariatric procedures\u20142019 update: cosponsored by American Association of Clinical Endocrinologists\/American College of Endocrinology, the Obesity Society, American Society for Metabolic & Bariatric Surgery, Obesity Medicine Association, and American Society of Anesthesiologists\u2014executive summary","volume":"25","author":"Mechanick","year":"2019","journal-title":"Endocr Pract"},{"key":"2026043016084999000_zrag025-B14","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/ACO.0000000000000542","article-title":"Obstructive sleep apnea and bariatric surgical guidelines: summary and update","volume":"31","author":"de Raaff","year":"2018","journal-title":"Curr Opin Anaesthesiol"},{"key":"2026043016084999000_zrag025-B15","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1754-9493-8-13","article-title":"Incidence of perioperative sleep-disordered breathing in patients undergoing major surgery: a prospective cohort study","volume":"8","author":"Roggenbach","year":"2014","journal-title":"Patient Saf Surg"},{"key":"2026043016084999000_zrag025-B16","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications","volume":"240","author":"Dindo","year":"2004","journal-title":"Ann Surg"},{"key":"2026043016084999000_zrag025-B17","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1183\/09031936.00212711","article-title":"Sleep apnoea is a common occurrence in females","volume":"41","author":"Franklin","year":"2013","journal-title":"Eur Respir J"},{"key":"2026043016084999000_zrag025-B18","doi-asserted-by":"crossref","first-page":"e13599","DOI":"10.1111\/jsr.13599","article-title":"Rapid eye movement sleep apnea and carotid intima thickness in men and women: a SHE-MUSTACHE cohort study","volume":"31","author":"Ljunggren","year":"2022","journal-title":"J Sleep Res"},{"key":"2026043016084999000_zrag025-B19","doi-asserted-by":"crossref","first-page":"597","DOI":"10.5664\/jcsm.2172","article-title":"Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. 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