{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T12:16:09Z","timestamp":1788524169000,"version":"build-2803163510"},"reference-count":51,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Department of Surgery, University Hospital of Basel and Hand in Hand Anstalt"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The oncological non-inferiority of sentinel lymph node biopsy omission in patients with small, clinically and imaging node-negative (cN0\/iN0) breast cancer has been demonstrated for patients undergoing breast-conserving surgery and adjuvant radiotherapy, but not for those undergoing mastectomy. This single-centre, retrospective cohort study compared nodal involvement and adjuvant therapy indications in these patients by use of mastectomy versus breast-conserving surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with cT1-T2, cN0\/iN0, hormone receptor-positive\/human epidermal growth factor receptor 2-negative early breast cancer who underwent upfront surgery including sentinel lymph node biopsy between January 2014 and December 2024 were included. Adjuvant therapy indications were estimated using monarchE (abemaciclib), NATALEE (ribociclib), TAILORx and RxPONDER (chemotherapy), and MA.20 and EORTC22922\/10925 (nodal irradiation) eligibility criteria. Multivariable logistic regression models identified factors associated with nodal involvement and adjuvant treatment indications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 454 patients, 145 (31.9%) underwent mastectomy who more frequently had multifocal tumours (23.5% versus 9.7%), lobular subtype (21.4% versus 11.3%), and grade 2\u20133 differentiation (73.8% versus 63.8%) compared with those who underwent breast-conserving surgery. Neither nodal involvement (18.6% versus 14.9%; P = 0.149) nor missed indications for adjuvant abemaciclib (7.6% versus 6.1%; P = 0.550), ribociclib (9.7% versus 7.8%; P = 0.586), and nodal irradiation (4.8% versus 4.5%; P = 1.000) differed between patients who underwent mastectomy or breast-conserving surgery. Lymphovascular invasion was independently associated with nodal involvement (odds ratio 6.8, 95% confidence interval 3.7 to 12.8; P &amp;lt; 0.001) and adjuvant treatment indications (CDK4\/6 inhibitors: odds ratio 5.1, 2.6 to 10.1; P &amp;lt; 0.001; nodal irradiation: odds ratio 7.1, 3.6 to 14.4; P &amp;lt; 0.001), whereas type of surgery was not.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In patients with cT1-T2, cN0\/iN0, hormone receptor-positive\/human epidermal growth factor receptor 2-negative breast cancer, type of breast surgery was not associated with nodal involvement and adjuvant therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bjsopen\/zrag105","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:48:34Z","timestamp":1782866914000},"source":"Crossref","is-referenced-by-count":0,"title":["Role of sentinel lymph node biopsy in patients with early breast cancer undergoing mastectomy"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2816-1351","authenticated-orcid":false,"given":"Martin","family":"Heidinger","sequence":"first","affiliation":[{"name":"Breast Clinic, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"Gynaecology & Obstetrics, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"University of Basel Medical Faculty, , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Montagna","sequence":"additional","affiliation":[{"name":"Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center , New York, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian S","family":"Halbeisen","sequence":"additional","affiliation":[{"name":"Surgical Outcome Research Center, University Hospital Basel and University of Basel , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna-Lena","family":"Eberhardt","sequence":"additional","affiliation":[{"name":"Radiation Oncology, University Hospital Basel , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Maggi","sequence":"additional","affiliation":[{"name":"Breast Clinic, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"University of Basel Medical Faculty, , Basel ,","place":["Switzerland"]},{"name":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet , Stockholm ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Louise","family":"Frevert","sequence":"additional","affiliation":[{"name":"Breast Clinic, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"Gynaecology & Obstetrics, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"University of Basel Medical Faculty, , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karol","family":"Dollt","sequence":"additional","affiliation":[{"name":"Breast Clinic, University Hospital Basel , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rama","family":"Kiblawi","sequence":"additional","affiliation":[{"name":"Breast Clinic, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"Gynaecology & Obstetrics, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"University of Basel Medical Faculty, , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie M","family":"Loesch","sequence":"additional","affiliation":[{"name":"Breast Clinic, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"Gynaecology & Obstetrics, University Hospital Basel , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena","family":"Winkler","sequence":"additional","affiliation":[{"name":"Radiation Oncology, University Hospital Basel , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabienne D","family":"Schwab","sequence":"additional","affiliation":[{"name":"Breast Clinic, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"Gynaecology & Obstetrics, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"University of Basel Medical Faculty, , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Kurzeder","sequence":"additional","affiliation":[{"name":"Breast Clinic, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"Gynaecology & Obstetrics, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"University of Basel Medical Faculty, , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tibor A","family":"Zwimpfer","sequence":"additional","affiliation":[{"name":"Gynaecology & Obstetrics, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"University of Basel Medical Faculty, , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter P","family":"Weber","sequence":"additional","affiliation":[{"name":"Breast Clinic, University Hospital Basel , Basel ,","place":["Switzerland"]},{"name":"University of Basel Medical Faculty, , Basel ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"2026090407401671600_zrag105-B1","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1001\/jamaoncol.2023.3759","article-title":"Sentinel lymph node biopsy vs no axillary surgery in patients with small breast cancer and negative results on ultrasonography of axillary lymph nodes: the SOUND Randomized Clinical Trial","volume":"9","author":"Gentilini","year":"2023","journal-title":"JAMA Oncol"},{"key":"2026090407401671600_zrag105-B2","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1056\/NEJMoa2412063","article-title":"Axillary surgery in breast cancer\u2014primary results of the INSEMA trial","volume":"392","author":"Reimer","year":"2025","journal-title":"N Engl J Med"},{"key":"2026090407401671600_zrag105-B3","author":"Schipper"},{"key":"2026090407401671600_zrag105-B4","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.ejso.2016.01.020","article-title":"Physical function of the upper limb after breast cancer surgery. Results from the SOUND (Sentinel node vs. Observation after axillary Ultra-souND) trial","volume":"42","author":"Gentilini","year":"2016","journal-title":"Eur J Surg Oncol"},{"key":"2026090407401671600_zrag105-B5","doi-asserted-by":"crossref","first-page":"101756","DOI":"10.1016\/j.eclinm.2022.101756","article-title":"Patient-reported outcomes for the Intergroup Sentinel Mamma study (INSEMA): a randomised trial with persistent impact of axillary surgery on arm and breast symptoms in patients with early breast cancer","volume":"55","author":"Reimer","year":"2023","journal-title":"EClinicalMedicine"},{"key":"2026090407401671600_zrag105-B6","doi-asserted-by":"crossref","first-page":"znaf031","DOI":"10.1093\/bjs\/znaf031","article-title":"Three-year patient-reported outcomes of the BOOG 2013-08 RCT evaluating omission of sentinel lymph node biopsy in early-stage breast cancer patients treated with breast conserving surgery: impact of personality traits on health-related quality of life","volume":"112","author":"Wintraecken","year":"2025","journal-title":"Br J Surg"},{"key":"2026090407401671600_zrag105-B7","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1001\/jamasurg.2022.2065","article-title":"Analysis of a trend reversal in US lumpectomy rates from 2005 through 2017 using 3 nationwide data sets","volume":"157","author":"Nelson","year":"2022","journal-title":"JAMA Surg"},{"key":"2026090407401671600_zrag105-B8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.breast.2018.02.003","article-title":"Mastectomy patterns, but not rates, are changing in the treatment of early breast cancer. Experience of a single European institution on 2315 consecutive patients","volume":"39","author":"Fancellu","year":"2018","journal-title":"Breast"},{"key":"2026090407401671600_zrag105-B9","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1200\/JCO.1992.10.6.976","article-title":"Mastectomy versus breast-conserving therapy in the treatment of stage I and II carcinoma of the breast: a randomized trial at the National Cancer Institute","volume":"10","author":"Lichter","year":"1992","journal-title":"J Clin Oncol"},{"key":"2026090407401671600_zrag105-B10","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1056\/NEJMoa022152","article-title":"Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer","volume":"347","author":"Fisher","year":"2002","journal-title":"N Engl J Med"},{"key":"2026090407401671600_zrag105-B11","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/ijc.31034","article-title":"Breast conserving therapy and mastectomy revisited: breast cancer-specific survival and the influence of prognostic factors in 129,692 patients","volume":"142","author":"Lagendijk","year":"2018","journal-title":"Int J Cancer"},{"key":"2026090407401671600_zrag105-B12","doi-asserted-by":"crossref","first-page":"9757","DOI":"10.1245\/s10434-025-18030-0","article-title":"Comparing survival differences between patients undergoing breast-conserving therapy versus total mastectomy as a first treatment for early stage breast cancer","volume":"32","author":"Yi","year":"2025","journal-title":"Ann Surg Oncol"},{"key":"2026090407401671600_zrag105-B13","doi-asserted-by":"crossref","first-page":"103614","DOI":"10.1016\/j.breast.2023.103614","article-title":"Association of clinicopathologic variables and patient preference with the choice of surgical treatment for early-stage breast cancer: a registry-based study","volume":"73","author":"S\u00f6derberg","year":"2024","journal-title":"Breast"},{"key":"2026090407401671600_zrag105-B14","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.jclinepi.2007.11.008","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"61","author":"von Elm","year":"2008","journal-title":"J Clin Epidemiol"},{"key":"2026090407401671600_zrag105-B15","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1200\/JCO.23.01994","article-title":"Adjuvant abemaciclib plus endocrine therapy for hormone receptor\u2013positive, human epidermal growth factor receptor 2\u2013negative, high-risk early breast cancer: results from a preplanned monarchE overall survival interim analysis, including 5-year efficacy outcomes","volume":"42","author":"Rastogi","year":"2024","journal-title":"J Clin Oncol"},{"key":"2026090407401671600_zrag105-B16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.annonc.2024.10.015","article-title":"A phase III trial of adjuvant ribociclib plus endocrine therapy versus endocrine therapy alone in patients with HR-positive\/HER2-negative early breast cancer: final invasive disease-free survival results from the NATALEE trial","volume":"36","author":"Hortobagyi","year":"2025","journal-title":"Ann Oncol"},{"key":"2026090407401671600_zrag105-B17","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1056\/NEJMoa1804710","article-title":"Adjuvant chemotherapy guided by a 21-gene expression assay in breast cancer","volume":"379","author":"Sparano","year":"2018","journal-title":"N Engl J Med"},{"key":"2026090407401671600_zrag105-B18","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1056\/NEJMoa2108873","article-title":"21-Gene assay to inform chemotherapy benefit in node-positive breast cancer","volume":"385","author":"Kalinsky","year":"2021","journal-title":"N Engl J Med"},{"key":"2026090407401671600_zrag105-B19","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1056\/NEJMoa1415340","article-title":"Regional nodal irradiation in early-stage breast cancer","volume":"373","author":"Whelan","year":"2015","journal-title":"N Engl J Med"},{"key":"2026090407401671600_zrag105-B20","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1016\/S1470-2045(20)30472-1","article-title":"Internal mammary and medial supraclavicular lymph node chain irradiation in stage I\u2013III breast cancer (EORTC 22922\/10925): 15-year results of a randomised, phase 3 trial","volume":"21","author":"Poortmans","year":"2020","journal-title":"Lancet Oncol"},{"key":"2026090407401671600_zrag105-B21","author":"Gradishar"},{"key":"2026090407401671600_zrag105-B22","author":"AWMF Leitlinie"},{"key":"2026090407401671600_zrag105-B23","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1093\/annonc\/mdy155","article-title":"Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancer","volume":"29","author":"Hortobagyi","year":"2018","journal-title":"Ann Oncol"},{"key":"2026090407401671600_zrag105-B24","doi-asserted-by":"crossref","first-page":"105858","DOI":"10.1016\/j.esmoop.2025.105858","article-title":"LBA14\u2014adjuvant ribociclib (RIB) plus nonsteroidal aromatase inhibitor (NSAI) in patients (pts) with HR+\/HER2\u2212 early breast cancer (EBC): NATALEE 5-year outcomes","volume":"10","author":"Crown","year":"2025","journal-title":"ESMO Open"},{"key":"2026090407401671600_zrag105-B25","first-page":"93","article-title":"The eighth edition AJCC Cancer Staging Manual: continuing to build a bridge from a population-based to a more \u2018personalized\u2019 approach to cancer staging","volume":"67","author":"Amin","year":"2017","journal-title":"CA Cancer J Clin"},{"key":"2026090407401671600_zrag105-B26","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1001\/jama.2017.11470","article-title":"Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis: the ACOSOG Z0011 (Alliance) randomized clinical trial","volume":"318","author":"Giuliano","year":"2017","journal-title":"JAMA"},{"key":"2026090407401671600_zrag105-B27","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1200\/JCO.22.01565","article-title":"Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer: 10-year results of the Randomized Controlled EORTC 10981-22023 AMAROS Trial","volume":"41","author":"Bartels","year":"2023","journal-title":"J Clin Oncol"},{"key":"2026090407401671600_zrag105-B28","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1056\/NEJMoa2313487","article-title":"Omitting axillary dissection in breast cancer with sentinel-node metastases","volume":"390","author":"de Boniface","year":"2024","journal-title":"N Engl J Med"},{"key":"2026090407401671600_zrag105-B29","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s12885-022-09273-1","article-title":"No axillary surgical treatment for lymph node-negative patients after ultra-sonography [NAUTILUS]: protocol of a prospective randomized clinical trial","volume":"22","author":"Jung","year":"2022","journal-title":"BMC Cancer"},{"key":"2026090407401671600_zrag105-B30"},{"key":"2026090407401671600_zrag105-B31"},{"key":"2026090407401671600_zrag105-B32","doi-asserted-by":"crossref","first-page":"e539","DOI":"10.1016\/j.clbc.2017.12.013","article-title":"Review of factors influencing women\u2019s choice of mastectomy versus breast conserving therapy in early stage breast cancer: a systematic review","volume":"18","author":"Gu","year":"2018","journal-title":"Clin Breast Cancer"},{"key":"2026090407401671600_zrag105-B33","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1200\/JCO.20.00299","article-title":"Management of hereditary breast cancer: American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology guideline","volume":"38","author":"Tung","year":"2020","journal-title":"J Clin Oncol"},{"key":"2026090407401671600_zrag105-B34","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.prro.2020.04.003","article-title":"ASTRO radiation therapy summary of the ASCO-ASTRO-SSO guideline on management of hereditary breast cancer","volume":"10","author":"Trombetta","year":"2020","journal-title":"Pract Radiat Oncol"},{"key":"2026090407401671600_zrag105-B35","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S1470-2045(14)70460-7","article-title":"Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial","volume":"15","author":"Donker","year":"2014","journal-title":"Lancet Oncol"},{"key":"2026090407401671600_zrag105-B36","doi-asserted-by":"publisher","first-page":"6414","DOI":"10.1245\/s10434-026-19588-z","article-title":"Implications for sentinel lymph node biopsy omission in patients with early-stage node-negative HR+\/HER2\u2212 breast cancer undergoing mastectomy","volume":"33","author":"Chen","year":"2026","journal-title":"Ann Surg Oncol"},{"key":"2026090407401671600_zrag105-B37","doi-asserted-by":"crossref","first-page":"3670","DOI":"10.1200\/JCO.2006.08.8013","article-title":"Doctor, what are my chances of having a positive sentinel node? A validated nomogram for risk estimation","volume":"25","author":"Bevilacqua","year":"2007","journal-title":"J Clin Oncol"},{"key":"2026090407401671600_zrag105-B38","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0360-3016(00)00605-2","article-title":"The relationship between lymphatic vessell invasion, tumor size, and pathologic nodal status: can we predict who can avoid a third field in the absence of axillary dissection?","volume":"48","author":"Wong","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2026090407401671600_zrag105-B39","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1200\/JCO-24-02683","article-title":"Why we do not recommend that women with breast cancer receive adjuvant treatment with a CDK4\/6 inhibitor","volume":"43","author":"Tannock","year":"2025","journal-title":"J Clin Oncol"},{"key":"2026090407401671600_zrag105-B40","doi-asserted-by":"crossref","first-page":"102944","DOI":"10.1016\/j.ctrv.2025.102944","article-title":"Adjuvant CDK4\/6 inhibitors in breast cancer: interpreting trial design, evidence, and uncertainty","volume":"136","author":"Niraula","year":"2025","journal-title":"Cancer Treat Rev"},{"key":"2026090407401671600_zrag105-B41","doi-asserted-by":"crossref","first-page":"104641","DOI":"10.1016\/j.breast.2025.104641","article-title":"Omission of sentinel lymph node biopsy in early stage luminal breast cancer: impact on adjuvant CDK4\/6 inhibitor recommendation and oncological outcomes","volume":"85","author":"Heidinger","year":"2026","journal-title":"The Breast"},{"key":"2026090407401671600_zrag105-B42","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1056\/NEJMoa2412225","article-title":"Ten-year survival after postmastectomy chest-wall irradiation in breast cancer","volume":"393","author":"Kunkler","year":"2025","journal-title":"N Engl J Med"},{"key":"2026090407401671600_zrag105-B43","author":"Hildebrandt"},{"key":"2026090407401671600_zrag105-B44","doi-asserted-by":"crossref","first-page":"110069","DOI":"10.1016\/j.radonc.2023.110069","article-title":"Quality assurance of radiation therapy after breast-conserving surgery among patients in the BOOG 2013-08 trial","volume":"191","author":"Wintraecken","year":"2024","journal-title":"Radiother Oncol"},{"key":"2026090407401671600_zrag105-B45","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00000478-200301000-00002","article-title":"Correlation of histologic prognostic factors in core biopsies and therapeutic excisions of invasive breast carcinoma","volume":"27","author":"Harris","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"2026090407401671600_zrag105-B46","doi-asserted-by":"crossref","first-page":"P5-01-08","DOI":"10.1158\/1538-7445.SABCS22-P5-01-08","article-title":"Abstract P5-01-08: steps toward noninvasive lymph node staging (NILS) in clinically node negative patients: artificial neural network model to preoperatively predict lymphovascular invasion","volume":"83","author":"Hj\u00e4rtstr\u00f6m","year":"2023","journal-title":"Cancer Res"},{"key":"2026090407401671600_zrag105-B47","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1136\/jclinpath-2017-204981","article-title":"Diagnostic concordance of reporting lymphovascular invasion in breast cancer","volume":"71","author":"Rakha","year":"2018","journal-title":"J Clin Pathol"},{"key":"2026090407401671600_zrag105-B48","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.critrevonc.2013.08.014","article-title":"The role of lymphatic and blood vessel invasion in predicting survival and methods of detection in patients with primary operable breast cancer","volume":"89","author":"Gujam","year":"2014","journal-title":"Crit Rev Oncol Hematol"},{"key":"2026090407401671600_zrag105-B49","doi-asserted-by":"crossref","first-page":"4064","DOI":"10.1245\/s10434-022-13064-0","article-title":"Delayed sentinel lymph node dissection in patients with a preoperative diagnosis of ductal cancer in situ by preoperative injection with superparamagnetic iron oxide (SPIO) nanoparticles: the SentiNot study","volume":"30","author":"Karakatsanis","year":"2023","journal-title":"Ann Surg Oncol"},{"key":"2026090407401671600_zrag105-B50","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1200\/JCO-25-00099","article-title":"Sentinel lymph node biopsy in early-stage breast cancer: ASCO guideline update","volume":"43","author":"Park","year":"2025","journal-title":"J Clin Oncol"},{"key":"2026090407401671600_zrag105-B51","author":"AGO Mamma"}],"container-title":["BJS Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/bjsopen\/article-pdf\/10\/5\/zrag105\/70962472\/zrag105.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/bjsopen\/article-pdf\/10\/5\/zrag105\/70962472\/zrag105.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:41:01Z","timestamp":1788522061000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/bjsopen\/article\/doi\/10.1093\/bjsopen\/zrag105\/8785680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,4]]},"references-count":51,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,9,4]]}},"URL":"https:\/\/doi.org\/10.1093\/bjsopen\/zrag105","relation":{},"ISSN":["2474-9842"],"issn-type":[{"value":"2474-9842","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,10]]},"published":{"date-parts":[[2026,9,4]]},"article-number":"zrag105"}}