{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:36:47Z","timestamp":1792625807401,"version":"4.5.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T00:00:00Z","timestamp":1686960000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Transient bone osteoporosis (TBO) is characterized by persistent pain, loss of function, no history of trauma and magnetic resonance image (MRI) findings of bone marrow edema.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Source of data<\/jats:title>\n                  <jats:p>PubMed, Google scholar, EMABSE and Web of Science were accessed in February 2023. No time constrains were used for the search.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Areas of agreement<\/jats:title>\n                  <jats:p>TBO is rare and misunderstood, typically affecting women during the third trimester of pregnancy or middle-aged men, leading to functional disability for 4\u20138\u00a0weeks followed by self-resolution of the symptoms.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Areas of controversy<\/jats:title>\n                  <jats:p>Given the limited evidence in the current literature, consensus on optimal management is lacking.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Growing points<\/jats:title>\n                  <jats:p>This systematic review investigates current management of TBO.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Areas timely for developing research<\/jats:title>\n                  <jats:p>A conservative approach leads to the resolution of symptoms and MRI findings at midterm follow-up. Administration of bisphosphonates might alleviate pain and accelerate both clinical and imaging recovery.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/bmb\/ldad012","type":"journal-article","created":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T04:24:45Z","timestamp":1686975885000},"page":"79-89","source":"Crossref","is-referenced-by-count":21,"title":["Management of transient bone osteoporosis: a systematic review"],"prefix":"10.1093","volume":"147","author":[{"given":"Filippo","family":"Migliorini","sequence":"first","affiliation":[{"name":"Department of Orthopaedic , Trauma, and Reconstructive Surgery, , 52074 Aachen , Germany"},{"name":"RWTH University Hospital , Trauma, and Reconstructive Surgery, , 52074 Aachen , Germany"},{"name":"Department of Orthopaedics and Trauma Surgery, Academic Hospital of Bolzano (SABES-ASDAA) , 39100 Bolzano , 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Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Bell","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic and Trauma Surgery, Eifelklinik St.Brigida , 52152 Simmerath , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Maffulli","sequence":"additional","affiliation":[{"name":"Department of Medicine , Surgery and Dentistry, , 84081 Baronissi, SA , Italy"},{"name":"University of Salerno , Surgery and Dentistry, , 84081 Baronissi, SA , Italy"},{"name":"School of Pharmacy and Bioengineering, Keele University Faculty of Medicine , ST4 7QB Stoke on Trent, England"},{"name":"Barts and the London School of Medicine and Dentistry, Centre for Sports and Exercise Medicine, Mile End Hospital, Queen Mar y University of London , 275 Bancroft Road, London E1 4DG , 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