{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:13:41Z","timestamp":1792793621794,"version":"4.5.0"},"reference-count":204,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"Jiangsu Provincial Health International Exchange Support Program","award":["2023\/2024"],"award-info":[{"award-number":["2023\/2024"]}]},{"name":"Xuzhou Medical Key Talents Program","award":["XWRCHT20220047"],"award-info":[{"award-number":["XWRCHT20220047"]}]},{"name":"Research Project of Jiangsu Provincial Health Commission","award":["H2023023"],"award-info":[{"award-number":["H2023023"]}],"id":[{"id":"https:\/\/ror.org\/03eqskn19","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Surgical intervention remains a cornerstone to restore function after acute Achilles tendon rupture (AATR), but evidence-based guidelines for surgical management are limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Sources of data<\/jats:title>\n                    <jats:p>A steering committee of 40 orthopedic surgeons identified nine key clinical questions on the surgical management of AATR. A systematic search of PubMed, MEDLINE, Web of Science, Cochrane Library, and EMBASE was conducted for studies published since 1980.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Areas of agreement<\/jats:title>\n                    <jats:p>Surgical management represents a reliable option to manage patients who suffered AATR. A well-designed operative strategy is essential to facilitate early recovery and achieve optimal functional outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Areas of controversy<\/jats:title>\n                    <jats:p>The surgical management of AATR remains challenging, particularly with respect to defining surgical indications, determining the optimal timing of intervention, selecting the most appropriate patient positioning, choosing between open and minimally invasive techniques, deciding on the role of primary augmentation, and establishing evidence-based postoperative rehabilitation protocols.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Growing points<\/jats:title>\n                    <jats:p>In the absence of established guidelines for the surgical management of AATR, this evidence-based clinical practice guideline provides nine key recommendations designed to address current controversies in the field.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Areas timely for developing research<\/jats:title>\n                    <jats:p>Further studies are warranted to evaluate emerging strategies such as nutraceuticals, biomaterials, cellular therapies, bioprinting, gene therapy, and anti-inflammatory agents, as no single approach has yet been validated as the optimal method to accelerate or enhance recovery following AATR.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/bmb\/ldaf026","type":"journal-article","created":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T12:45:43Z","timestamp":1766666743000},"source":"Crossref","is-referenced-by-count":6,"title":["Evidence-based clinical practice guidelines on the surgical management of acute Achilles tendon rupture"],"prefix":"10.1093","volume":"157","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0815-2426","authenticated-orcid":false,"given":"Shi-Ming","family":"Feng","sequence":"first","affiliation":[{"name":"Sports Medicine Department, Xuzhou Central Hospital, Southeast University , No. 199 Jiefang South Road, Quanshan District, Xuzhou, Jiangsu 221009 ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5327-3702","authenticated-orcid":false,"given":"Nicola","family":"Maffulli","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic, University La Sapienza , Faculty of Medicine and Psychology, Via di Grottarossa, 00189, Rome ,","place":["Italy"]},{"name":"Guy Hilton Research Centre, School of Pharmacy and Bioengineering, Keele University , Stoke-on-Trent, Staffordshire ST4 7QB, England"},{"name":"Centre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry , Mile End Hospital, 275 Bancroft Road, London E1 4DG, England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7473-0271","authenticated-orcid":false,"given":"Francesco","family":"Oliva","sequence":"additional","affiliation":[{"name":"Department of Sports Traumatology, Universita\u2019 Telematica San Raffaele , Via di Val Cannuta, 247, 00166 Roma ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Paul","sequence":"additional","affiliation":[{"name":"Department of Orthopedic and Trauma Surgery, Johanniter Waldkrankenhaus Bonn , Waldstra\u00dfe 73, Bonn 53177, \u00a0","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3946-1165","authenticated-orcid":false,"given":"Kai","family":"Fehske","sequence":"additional","affiliation":[{"name":"Department of Orthopedic and Trauma Surgery, Johanniter Waldkrankenhaus Bonn , Waldstra\u00dfe 73, Bonn 53177, \u00a0","place":["Germany"]},{"name":"Department of Trauma Surgery, University Hosptial Wuerzburg , Wuerzburg ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0568-2074","authenticated-orcid":false,"given":"Christian","family":"Plaass","sequence":"additional","affiliation":[{"name":"Department for Foot and Ankle Surgery, DIAKOVERE Annastift, Orthopedic Clinic of the Hannover Medical School , Anna-von-Borries Strasse 1-7, Hannover 30625 ,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5404-5179","authenticated-orcid":false,"given":"Thomas","family":"Karius","sequence":"additional","affiliation":[{"name":"Department of Orthopedic and Trauma Surgery, Johanniter Waldkrankenhaus Bonn , Waldstra\u00dfe 73, Bonn 53177, 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