{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T03:13:39Z","timestamp":1790565219158,"version":"4.1.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Canada Research Chair in Genetics of the Nervous System"},{"name":"Wilder Penfield Chair in Neurosciences"},{"name":"Canadian Institutes of Health Research Foundation Scheme","award":["#332971"],"award-info":[{"award-number":["#332971"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11,1]]},"DOI":"10.1093\/brain\/awaa291","type":"journal-article","created":{"date-parts":[[2020,8,18]],"date-time":"2020-08-18T04:49:49Z","timestamp":1597726189000},"page":"e89-e89","source":"Crossref","is-referenced-by-count":15,"title":["Assessing the <i>NOTCH2NLC<\/i> GGC expansion in European patients with essential tremor"],"prefix":"10.1093","volume":"143","author":[{"given":"Calwing","family":"Liao","sequence":"first","affiliation":[{"name":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada"},{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulya","family":"Ak\u00e7imen","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada"},{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Diez-Fairen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle","family":"Houle","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada"},{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8183-2524","authenticated-orcid":false,"given":"Jay P","family":"Ross","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada"},{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe","family":"Schmilovich","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada"},{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Spiegelman","sequence":"additional","affiliation":[{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veikko","family":"Vuokila","sequence":"additional","affiliation":[{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9l\u00e8ne","family":"Catoire","sequence":"additional","affiliation":[{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inge A","family":"Meijer","sequence":"additional","affiliation":[{"name":"Department of Neuroscience and Pediatrics, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7493-8777","authenticated-orcid":false,"given":"Pau","family":"Pastor","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital Universitari Mutua de Terrassa, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Rajput","sequence":"additional","affiliation":[{"name":"Division of Neurology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick A","family":"Dion","sequence":"additional","affiliation":[{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"},{"name":"Department of Neurology and Neurosurgery, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8403-1418","authenticated-orcid":false,"given":"Guy A","family":"Rouleau","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada"},{"name":"Montreal Neurological Institute, McGill University, Montr\u00e9al, Quebec, Canada"},{"name":"Department of Neurology and Neurosurgery, McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,11,4]]},"reference":[{"key":"2021012814053197000_awaa291-B1","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.neurol.2015.02.015","article-title":"Challenges in essential tremor genetics","volume":"171","author":"Clark","year":"2015","journal-title":"Rev Neurol (Paris)"},{"key":"2021012814053197000_awaa291-B2","doi-asserted-by":"crossref","first-page":"5677","DOI":"10.1093\/hmg\/ddv281","article-title":"Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor","volume":"24","author":"Hor","year":"2015","journal-title":"Hum Mol Genet"},{"key":"2021012814053197000_awaa291-B3","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S0140-6736(16)00143-4","article-title":"Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study","volume":"387","author":"Hou","year":"2016","journal-title":"Lancet"},{"key":"2021012814053197000_awaa291-B4","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/mds.26753","article-title":"Teneurin transmembrane protein 4 is not a cause for essential tremor in a Canadian population","volume":"32","author":"Houle","year":"2017","journal-title":"Mov Disord"},{"key":"2021012814053197000_awaa291-B5","first-page":"813","article-title":"Sarayloo F","volume":"11","year":"2020","journal-title":"Vuokila V, Rochefort D, Ak\u00e7imen F, Diamond S, et al. Transcriptomic Changes Resulting from STK32B Overexpression Identify Pathways Potentially Relevant to Essential Tremor. Front Genet"},{"key":"2021012814053197000_awaa291-B6","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1002\/mds.28031","article-title":"Multiomics analyses identify genes and pathways relevant to essential tremor","volume":"35","author":"Liao","year":"2020","journal-title":"Mov Disord"},{"key":"2021012814053197000_awaa291-B7","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000356351","article-title":"Essential tremor\u2019 or \u2018the essential tremors\u2019: is this one disease or a family of diseases?","volume":"42","author":"Louis","year":"2014","journal-title":"Neuroepidemiology"},{"key":"2021012814053197000_awaa291-B8","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ajhg.2012.07.002","article-title":"Exome Sequencing Identifies FUS mutations as a cause of essential tremor","volume":"91","author":"Merner","year":"2012","journal-title":"Am J Hum Genet"},{"key":"2021012814053197000_awaa291-B9","doi-asserted-by":"crossref","first-page":"3163","DOI":"10.1093\/brain\/aww242","article-title":"Genome-wide association study in essential tremor identifies three new loci","volume":"139","author":"M\u00fcller","year":"2016","journal-title":"Brain"},{"key":"2021012814053197000_awaa291-B10","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1093\/brain\/awz372","article-title":"Expansion of GGC repeat in the human-specific NOTCH2NLC gene is associated with essential tremor","volume":"143","author":"Sun","year":"2020","journal-title":"Brain"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/143\/11\/e89\/36134920\/awaa291.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/143\/11\/e89\/36134920\/awaa291.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,28]],"date-time":"2021-01-28T21:03:22Z","timestamp":1611867802000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article\/143\/11\/e89\/5955876"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,1]]},"references-count":10,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2020,11,4]]},"published-print":{"date-parts":[[2020,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awaa291","relation":{},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,11,1]]},"published":{"date-parts":[[2020,11,1]]}}}