{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:42:01Z","timestamp":1790775721276,"version":"4.1.0"},"reference-count":95,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2020,11,22]],"date-time":"2020-11-22T00:00:00Z","timestamp":1606003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"The French Ministry of Health"},{"name":"PHRC","award":["2011-A00681-40"],"award-info":[{"award-number":["2011-A00681-40"]}]},{"name":"University of Caen-Normandie"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The most recent theories of emotions have postulated that their expression and recognition depend on acquired conceptual knowledge. In other words, the conceptual knowledge derived from prior experiences guide our ability to make sense of such emotions. However, clear evidence is still lacking to contradict more traditional theories, considering emotions as innate, distinct and universal physiological states. In addition, whether valence processing (i.e. recognition of the pleasant\/unpleasant character of emotions) also relies on semantic knowledge is yet to be determined. To investigate the contribution of semantic knowledge to facial emotion recognition and valence processing, we conducted a behavioural and neuroimaging study in 20 controls and 16 patients with the semantic variant of primary progressive aphasia, a neurodegenerative disease that is prototypical of semantic memory impairment, and in which an emotion recognition deficit has already been described. We assessed participants\u2019 knowledge of emotion concepts and recognition of 10 basic (e.g. anger) or self-conscious (e.g. embarrassment) facial emotional expressions presented both statically (images) and dynamically (videos). All participants also underwent a brain MRI. Group comparisons revealed deficits in both emotion concept knowledge and emotion recognition in patients, independently of type of emotion and presentation. These measures were significantly correlated with each other in patients and with semantic fluency in patients and controls. Neuroimaging analyses showed that both emotion recognition and emotion conceptual knowledge were correlated with reduced grey matter density in similar areas within frontal ventral, temporal, insular and striatal regions, together with white fibre degeneration in tracts connecting frontal regions with each other as well as with temporal regions. We then performed a qualitative analysis of responses made during the facial emotion recognition task, by delineating valence errors (when one emotion was mistaken for another of a different valence), from other errors made during the emotion recognition test. We found that patients made more valence errors. The number of valence errors correlated with emotion conceptual knowledge as well as with reduced grey matter volume in brain regions already retrieved to correlate with this score. Specificity analyses allowed us to conclude that this cognitive relationship and anatomical overlap were not mediated by a general effect of disease severity. Our findings suggest that semantic knowledge guides the recognition of emotions and is also involved in valence processing. Our study supports a constructionist view of emotion recognition and valence processing, and could help to refine current theories on the interweaving of semantic knowledge and emotion processing.<\/jats:p>","DOI":"10.1093\/brain\/awaa313","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T19:12:28Z","timestamp":1598555548000},"page":"3850-3864","source":"Crossref","is-referenced-by-count":63,"title":["When affect overlaps with concept: emotion recognition in semantic variant of primary progressive aphasia"],"prefix":"10.1093","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5283-503X","authenticated-orcid":false,"given":"Maxime","family":"Bertoux","sequence":"first","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"},{"name":"Univ. Lille, Inserm, CHU Lille, UMRS1172, Lille Neurosciences & Cognition Institute, F-59000 Lille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3509-6749","authenticated-orcid":false,"given":"Harmony","family":"Duclos","sequence":"additional","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"},{"name":"CRP-CPO, Picardy Jules Verne University, Amiens, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Caillaud","sequence":"additional","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1977-8210","authenticated-orcid":false,"given":"Shailendra","family":"Segobin","sequence":"additional","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Merck","sequence":"additional","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"},{"name":"Neurology Department, Pontchaillou University Hospital, Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"de La Sayette","sequence":"additional","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"},{"name":"Neurology Department, Caen University Hospital, Caen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serge","family":"Belliard","sequence":"additional","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"},{"name":"Neurology Department, Pontchaillou University Hospital, Rennes, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9atrice","family":"Desgranges","sequence":"additional","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Eustache","sequence":"additional","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micka\u00ebl","family":"Laisney","sequence":"additional","affiliation":[{"name":"Neuropsychology and Imaging of Human Memory research unit, Caen-Normandy University-PSL Research University-EPHE-INSERM-Caen University Hospital, UMRS1077, GIP Cyceron, Caen, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,11,22]]},"reference":[{"key":"2021012714253008400_awaa313-B1","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.cortex.2016.12.019","article-title":"Convergence of interoception, emotion, and social cognition: a twofold fMRI meta-analysis and lesion approach","volume":"88","author":"Adolfi","year":"2017","journal-title":"Cortex"},{"key":"2021012714253008400_awaa313-B2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0278-2626(03)00009-5","article-title":"Dissociable neural systems for recognizing emotions","volume":"52","author":"Adolphs","year":"2003","journal-title":"Brain Cogn"},{"key":"2021012714253008400_awaa313-B3","author":"Andersson","year":"2007"},{"key":"2021012714253008400_awaa313-B4","author":"Andersson","year":"2007"},{"key":"2021012714253008400_awaa313-B5","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1006\/nimg.2000.0582","article-title":"Voxel-based morphometry\u2013the methods","volume":"11 (6 Pt 1","author":"Ashburner","year":"2000","journal-title":"Neuroimage"},{"key":"2021012714253008400_awaa313-B6","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/7854_2016_443","article-title":"The social context network model in psychiatric and neurological diseases","volume":"30","author":"Baez","year":"2017","journal-title":"Curr Top Behav Neurosci"},{"key":"2021012714253008400_awaa313-B7","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1152\/ajplegacy.1928.84.3.490","article-title":"A diencephalic mechanism for the expression of rage with special reference to the sympathetic nervous system","volume":"84","author":"Bard","year":"1928","journal-title":"Am J Physiol"},{"key":"2021012714253008400_awaa313-B8","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1207\/s15327957pspr1001_2","article-title":"Solving the emotion paradox: categorization and the experience of emotion","volume":"10","author":"Barrett","year":"2006","journal-title":"Pers Soc Psychol Rev"},{"key":"2021012714253008400_awaa313-B9","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1146\/annurev.psych.58.110405.085709","article-title":"The experience of emotion","volume":"58","author":"Barrett","year":"2007","journal-title":"Annu Rev Psychol"},{"key":"2021012714253008400_awaa313-B10","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1146\/annurev.psych.59.103006.093639","article-title":"Grounded cognition","volume":"59","author":"Barsalou","year":"2008","journal-title":"Annu Rev Psychol"},{"key":"2021012714253008400_awaa313-B11","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1017\/S1355617712001300","article-title":"Social cognition and emotional assessment (SEA) is a marker of medial and orbital frontal functions: a voxel-based morphometry study in behavioral variant of frontotemporal degeneration","volume":"18","author":"Bertoux","year":"2012","journal-title":"J Int Neuropsychol Soc"},{"key":"2021012714253008400_awaa313-B12","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.bandc.2009.02.009","article-title":"Empathy and emotion recognition in semantic dementia: a case report","volume":"70","author":"Calabria","year":"2009","journal-title":"Brain Cogn"},{"key":"2021012714253008400_awaa313-B13","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1080\/02699931.2015.1049124","article-title":"Perceptual and affective mechanisms in facial expression recognition: an integrative review","volume":"30","author":"Calvo","year":"2016","journal-title":"Cogn Emot"},{"key":"2021012714253008400_awaa313-B14","doi-asserted-by":"crossref","first-page":"106","DOI":"10.2307\/1415404","article-title":"The James-Lange theory of emotions: a critical examination and an alternative theory","volume":"39","author":"Cannon","year":"1927","journal-title":"Am J Psychol"},{"key":"2021012714253008400_awaa313-B15","first-page":"103","article-title":"Appraising valence","volume":"12","author":"Colombetti","year":"2005","journal-title":"J Consciousness Stud"},{"key":"2021012714253008400_awaa313-B16","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1037\/amp0000488","article-title":"What the face displays: mapping 28 emotions conveyed by naturalistic expression","volume":"75","author":"Cowen","year":"2020","journal-title":"Am Psychol"},{"key":"2021012714253008400_awaa313-B17","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/s41562-019-0533-6","article-title":"The primacy of categories in the recognition of 12 emotions in speech prosody across two cultures","volume":"3","author":"Cowen","year":"2019","journal-title":"Nat Hum Behav"},{"key":"2021012714253008400_awaa313-B18","doi-asserted-by":"crossref","DOI":"10.1037\/10001-000","volume-title":"The expression of the emotions in man and animals","author":"Darwin","year":"1872"},{"key":"2021012714253008400_awaa313-B19","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.nicl.2015.06.005","article-title":"White matter tract signatures of impaired social cognition in frontotemporal lobar degeneration","volume":"8","author":"Downey","year":"2015","journal-title":"Neuroimage Clin"},{"key":"2021012714253008400_awaa313-B20","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1037\/h0030377","article-title":"Constants across cultures in the face and emotion","volume":"17","author":"Ekman","year":"1971","journal-title":"J Pers Soc Psychol"},{"key":"2021012714253008400_awaa313-B21","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1177\/1754073911410740","article-title":"What is meant by calling emotions basic","volume":"3","author":"Ekman","year":"2011","journal-title":"Emotion Rev"},{"key":"2021012714253008400_awaa313-B22","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.neubiorev.2019.02.020","article-title":"More than words: social cognition across variants of primary progressive aphasia","volume":"100","author":"Fittipaldi","year":"2019","journal-title":"Neurosci Biobehav Rev"},{"key":"2021012714253008400_awaa313-B24","author":"Frijda","year":"1986"},{"key":"2021012714253008400_awaa313-B25","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.neubiorev.2015.02.004","article-title":"Is the difference between right and left ATLs due to the distinction between general and social cognition or between verbal and non-verbal representations?","volume":"51","author":"Gainotti","year":"2015","journal-title":"Neurosci Biobehav Rev"},{"key":"2021012714253008400_awaa313-B26","doi-asserted-by":"crossref","first-page":"20160006","DOI":"10.1098\/rstb.2016.0006","article-title":"Feeling, learning from and being aware of inner states: interoceptive dimensions in neurodegeneration and stroke","volume":"371","author":"Garc\u00eda-Cordero","year":"2016","journal-title":"Philos Trans R Soc B"},{"key":"2021012714253008400_awaa313-B27","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.nicl.2017.01.016","article-title":"A neural network underlying intentional emotional facial expression in neurodegenerative disease","volume":"14","author":"Gola","year":"2017","journal-title":"Neuroimage Clin"},{"key":"2021012714253008400_awaa313-B28","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1006\/nimg.2001.0786","article-title":"A voxel-based morphometric study of ageing in 465 normal adult human brains","volume":"14 (1 Pt 1","author":"Good","year":"2001","journal-title":"Neuroimage"},{"key":"2021012714253008400_awaa313-B29","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/nimg.2002.1202","article-title":"Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias","volume":"17","author":"Good","year":"2002","journal-title":"Neuromage"},{"key":"2021012714253008400_awaa313-B30","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1212\/WNL.0b013e31821103e6","article-title":"Classification of primary progressive aphasia and its variants","volume":"76","author":"Gorno-Tempini","year":"2011","journal-title":"Neurology"},{"key":"2021012714253008400_awaa313-B31","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1093\/brain\/awv245","article-title":"Reply: strategy and suppression impairments after right lateral and orbito-frontal lesions","volume":"139 (Pt 2","author":"Hornberger","year":"2016","journal-title":"Brain"},{"key":"2021012714253008400_awaa313-B32","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1016\/j.neuropsychologia.2012.04.006","article-title":"Brain correlates of musical and facial emotion recognition: evidence from the dementias","volume":"50","author":"Hsieh","year":"2012","journal-title":"Neuropsychologia"},{"key":"2021012714253008400_awaa313-B33","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.cortex.2019.01.024","article-title":"Insular networks and intercognition in the wild","volume":"115","author":"Ib\u00e1\u00f1ez","year":"2019","journal-title":"Cortex"},{"key":"2021012714253008400_awaa313-B34","first-page":"e15","article-title":"Reply: towards a neurocomputational account of social dysfunction in neurodegenerative disease","volume":"140","author":"Ib\u00e1\u00f1ez","year":"2017","journal-title":"Brain"},{"key":"2021012714253008400_awaa313-B35","author":"Ib\u00e1\u00f1ez","year":"2018"},{"key":"2021012714253008400_awaa313-B36","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1212\/WNL.0b013e3182518375","article-title":"Contextual social cognition and the behavioral variant of frontotemporal dementia","volume":"78","author":"Ib\u00e1\u00f1ez","year":"2012","journal-title":"Neurology"},{"key":"2021012714253008400_awaa313-B37","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1590\/S1980-57642013DN70100014","article-title":"A tale of two hemispheres: contrasting socioemotional dysfunction in right- versus left-lateralised semantic dementia","volume":"7","author":"Irish","year":"2013","journal-title":"Dement Neuropsychol"},{"key":"2021012714253008400_awaa313-B38","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1002\/hbm.22263","article-title":"Common and unique gray matter correlates of episodic memory dysfunction in frontotemporal dementia and Alzheimer's disease","volume":"35","author":"Irish","year":"2014","journal-title":"Hum Brain Mapp"},{"key":"2021012714253008400_awaa313-B39","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1093\/mind\/os-IX.34.188","article-title":"What is an emotion?","volume":"9","author":"James","year":"1884","journal-title":"Mind"},{"key":"2021012714253008400_awaa313-B40","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1006\/nimg.2002.1132","article-title":"Improved optimization for the robust and accurate linear registration and motion correction of brain images","volume":"17","author":"Jenkinson","year":"2002","journal-title":"Neuroimage"},{"key":"2021012714253008400_awaa313-B41","doi-asserted-by":"crossref","first-page":"e1003094","DOI":"10.1371\/journal.pcbi.1003094","article-title":"Emotional valence and the free-energy principle","volume":"9","author":"Joffily","year":"2013","journal-title":"PLoS Comput Biol"},{"key":"2021012714253008400_awaa313-B42","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1212\/WNL.0b013e3181bf9945","article-title":"Two distinct subtypes of right temporal variant frontotemporal dementia","volume":"73","author":"Josephs","year":"2009","journal-title":"Neurology"},{"key":"2021012714253008400_awaa313-B43","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1136\/jnnp-2014-309120","article-title":"Differentiating between right-lateralised semantic dementia and behavioural-variant frontotemporal dementia: an examination of clinical characteristics and emotion processing","volume":"86","author":"Kamminga","year":"2015","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2021012714253008400_awaa313-B44","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1017\/S0317167100021053","article-title":"Frontal Behavioral Inventory: diagnostic criteria for frontal lobe dementia","volume":"24","author":"Kertesz","year":"1997","journal-title":"Can J Neurol Sci"},{"key":"2021012714253008400_awaa313-B45","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1093\/brain\/awy002","article-title":"Beyond the face: how context modulates emotion processing in frontotemporal dementia subtypes","volume":"141","author":"Kumfor","year":"2018","journal-title":"Brain"},{"key":"2021012714253008400_awaa313-B46","doi-asserted-by":"crossref","first-page":"e67457","DOI":"10.1371\/journal.pone.0067457","article-title":"Discrete neural correlates for the recognition of negative emotions: insights from frontotemporal dementia","volume":"8","author":"Kumfor","year":"2013","journal-title":"PLoS One"},{"key":"2021012714253008400_awaa313-B47","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1093\/brain\/awv387","article-title":"On the right side? A longitudinal study of left- versus right-lateralized semantic dementia","volume":"139","author":"Kumfor","year":"2016","journal-title":"Brain"},{"key":"2021012714253008400_awaa313-B48","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1080\/17470919.2011.620779","article-title":"Are you really angry? The effect of intensity on facial emotion recognition in frontotemporal dementia","volume":"6","author":"Kumfor","year":"2011","journal-title":"Soc Neurosci"},{"key":"2021012714253008400_awaa313-B49","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1007\/s11065-012-9201-6","article-title":"Disturbance of emotion processing in frontotemporal dementia: a synthesis of cognitive and neuroimaging findings","volume":"22","author":"Kumfor","year":"2012","journal-title":"Neuropsychol Rev"},{"key":"2021012714253008400_awaa313-B50","author":"Lange","year":"1887","journal-title":"Eine psycho-physiologishe studie"},{"key":"2021012714253008400_awaa313-B51","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.tics.2012.09.005","article-title":"A functional architecture of the human brain: emerging insights from the science of emotion","volume":"16","author":"Lindquist","year":"2012","journal-title":"Trends Cogn Sci"},{"key":"2021012714253008400_awaa313-B52","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1037\/a0035293","article-title":"Emotion perception, but not affect perception, is impaired with semantic memory loss","volume":"14","author":"Lindquist","year":"2014","journal-title":"Emotion"},{"key":"2021012714253008400_awaa313-B53","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1037\/a0032283","article-title":"Do people essentialize emotions? Individual differences in emotion essentialism and emotional experience","volume":"13","author":"Lindquist","year":"2013","journal-title":"Emotion"},{"key":"2021012714253008400_awaa313-B54","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1080\/17470919.2019.1577295","article-title":"The contribution of semantic memory to the recognition of basic emotions and emotional valence: evidence from the semantic variant of primary progressive aphasia","volume":"14","author":"Macoir","year":"2019","journal-title":"Soc Neurosci"},{"key":"2021012714253008400_awaa313-B55","doi-asserted-by":"crossref","DOI":"10.1016\/j.copsyc.2017.06.009","article-title":"Visual perception of facial expressions of emotion","author":"Martinez","year":"2017","journal-title":"Curr Opin Psychol"},{"key":"2021012714253008400_awaa313-B56","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1093\/brain\/aww231","article-title":"Your perspective and my benefit: multiple lesion models of self-other integration strategies during social bargaining","volume":"139","author":"Melloni","year":"2016","journal-title":"Brain"},{"key":"2021012714253008400_awaa313-B57","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1155\/2012\/683052","article-title":"One size does not fit all: face emotion processing impairments in semantic dementia, behavioural-variant frontotemporal dementia and Alzheimer's disease are mediated by distinct cognitive deficits","volume":"25","author":"Miller","year":"2012","journal-title":"Behav Neurol"},{"key":"2021012714253008400_awaa313-B58","first-page":"297","article-title":"The cortical representation of emotion, with a discussion of some points in the general nervous system mechanism of expression in its relation to organic nervous disease and insanity","volume":"19","author":"Mills","year":"1912","journal-title":"Proc Am Med Psychol Assoc"},{"key":"2021012714253008400_awaa313-B59","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.nicl.2017.08.020","article-title":"Emotion detection deficits and changes in personality traits linked to loss of white matter integrity in primary progressive aphasia","volume":"16","author":"Multani","year":"2017","journal-title":"Neuroimage Clin"},{"key":"2021012714253008400_awaa313-B60","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3758\/CABN.3.3.207","article-title":"Functional neuroanatomy of emotions: a meta-analysis","volume":"3","author":"Murphy","year":"2003","journal-title":"Cogn Affect Behav Neurosci"},{"key":"2021012714253008400_awaa313-B61","doi-asserted-by":"crossref","first-page":"516","DOI":"10.3758\/BF03195598","article-title":"Lexique 2: a new French Lexical Database","volume":"36","author":"New","year":"2004","journal-title":"Behav Res Methods Instrum Comput"},{"key":"2021012714253008400_awaa313-B62","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1126\/science.1136930","article-title":"Embodying emotion","volume":"316","author":"Niedenthal","year":"2007","journal-title":"Science"},{"key":"2021012714253008400_awaa313-B63","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1093\/brain\/awv315","article-title":"Fair play: social norm compliance failures in behavioural variant frontotemporal dementia","volume":"139","author":"O\u2019Callaghan","year":"2016","journal-title":"Brain"},{"key":"2021012714253008400_awaa313-B64","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1093\/scan\/nss119","article-title":"Social cognition and the anterior 1456 temporal lobes: a review and theoretical framework","volume":"8","author":"Olson","year":"2013","journal-title":"Soc Cogn Affect Neurosci"},{"key":"2021012714253008400_awaa313-B65","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1093\/brain\/awm052","article-title":"The enigmatic temporal pole: a review of 1454 findings on social and emotional processing","volume":"130","author":"Olson","year":"2007","journal-title":"Brain"},{"key":"2021012714253008400_awaa313-B66","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1001\/archneurpsyc.1937.02260220069003","article-title":"A proposed mechanism of emotion","volume":"38","author":"Papez","year":"1937","journal-title":"Arch Neurpsychol"},{"key":"2021012714253008400_awaa313-B67","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/nrn2277","article-title":"Where do you know what you know? The representation of semantic knowledge in the human brain","volume":"8","author":"Patterson","year":"2007","journal-title":"Nat Rev Neurosci"},{"key":"2021012714253008400_awaa313-B68","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/neucas\/7.2.145","article-title":"Hemispheric dominance for emotions, empathy and social behaviour: evidence from right and left handers with frontotemporal dementia","volume":"7","author":"Perry","year":"2001","journal-title":"Neurocase"},{"key":"2021012714253008400_awaa313-B69","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1159\/000091898","article-title":"Orbitofrontal dysfunction related to both apathy and disinhibition in frontotemporal dementia","volume":"21","author":"Peters","year":"2006","journal-title":"Dement Geriatr Cogn Disord"},{"key":"2021012714253008400_awaa313-B70","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1162\/jocn_a_00902","article-title":"Hemispheric specialization within the superior anterior temporal cortex for social and nonsocial concepts","volume":"28","author":"Pobric","year":"2016","journal-title":"J Cogn Neurosci"},{"key":"2021012714253008400_awaa313-B71","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.3389\/fpsyg.2017.02056","article-title":"N170 reveals the categorical perception effect of emotional valence","volume":"8","author":"Qiu","year":"2017","journal-title":"Front Psychol"},{"key":"2021012714253008400_awaa313-B72","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/nyas.12951","article-title":"Graded specialization within and between the anterior temporal lobes","volume":"1359","author":"Rice","year":"2015","journal-title":"Ann NY Acad Sci"},{"key":"2021012714253008400_awaa313-B73","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.neuropsychologia.2017.09.021","article-title":"The orbitofrontal cortex and emotion in health and disease, including depression","volume":"128","author":"Rolls","year":"2019","journal-title":"Neuropsychologia"},{"key":"2021012714253008400_awaa313-B74","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1093\/brain\/awf225","article-title":"Emotion comprehension in the temporal variant of frontotemporal dementia","volume":"125","author":"Rosen","year":"2002","journal-title":"Brain"},{"key":"2021012714253008400_awaa313-B75","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1159\/000077154","article-title":"Recognition of emotion in the frontal and temporal variants of frontotemporal dementia","volume":"17","author":"Rosen","year":"2004","journal-title":"Dement Geriatr Cogn Disord"},{"key":"2021012714253008400_awaa313-B76","doi-asserted-by":"crossref","first-page":"R1083","DOI":"10.1016\/j.cub.2018.07.018","article-title":"Orbitofrontal cortex","volume":"28","author":"Rudebeck","year":"2018","journal-title":"Curr Biol"},{"key":"2021012714253008400_awaa313-B77","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1109\/42.796284","article-title":"Nonrigid registration using free-form deformations: application to breast MR images","volume":"18","author":"Rueckert","year":"1999","journal-title":"IEEE Trans Med Imaging"},{"key":"2021012714253008400_awaa313-B78","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1037\/0033-295X.110.1.145","article-title":"Core affect and the psychological construction of emotion","volume":"110","author":"Russell","year":"2003","journal-title":"Psychol Rev"},{"key":"2021012714253008400_awaa313-B79","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1037\/h0046234","article-title":"Cognitive, social, and physiological determinants of emotional state","volume":"69","author":"Schachter","year":"1962","journal-title":"Psychol Rev"},{"key":"2021012714253008400_awaa313-B80","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.neuron.2009.03.024","article-title":"Neurodegenerative diseases target large-scale human brain networks","volume":"62","author":"Seeley","year":"2009","journal-title":"Neuron"},{"key":"2021012714253008400_awaa313-B81","doi-asserted-by":"crossref","first-page":"2795","DOI":"10.1002\/hbm.22808","article-title":"Integrity of white matter microstructure in alcoholics with and without Korsakoff's syndrome","volume":"36","author":"Segobin","year":"2015","journal-title":"Hum Brain Mapp"},{"key":"2021012714253008400_awaa313-B82","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.tics.2015.11.002","article-title":"Forming beliefs: why valence matters","volume":"20","author":"Sharot","year":"2016","journal-title":"Trends Cogn Sci"},{"key":"2021012714253008400_awaa313-B83","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1080\/02699939308409189","article-title":"Appraisal components, core relational themes, and the emotions","volume":"7","author":"Smith","year":"1993","journal-title":"Cogn Emotion"},{"key":"2021012714253008400_awaa313-B84","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1016\/j.neuroimage.2006.02.024","article-title":"Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data","volume":"31","author":"Smith","year":"2006","journal-title":"Neuroimage"},{"key":"2021012714253008400_awaa313-B85","doi-asserted-by":"crossref","first-page":"S208","DOI":"10.1016\/j.neuroimage.2004.07.051","article-title":"Advances in functional and structural MR image analysis and implementation as FSL","volume":"23 (Suppl 1","author":"Smith","year":"2004","journal-title":"Neuroimage"},{"key":"2021012714253008400_awaa313-B86","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.neuroimage.2008.03.061","article-title":"Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference","volume":"44","author":"Smith","year":"2009","journal-title":"Neuroimage"},{"key":"2021012714253008400_awaa313-B87","first-page":"162","volume-title":"Not passion's slave: emotions and choice","author":"Solomon","year":"2001"},{"key":"2021012714253008400_awaa313-B88","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/1468-5914.00196","article-title":"On \u201cpositive\u201d and \u201cnegative\u201d emotions","volume":"32","author":"Solomon","year":"2002","journal-title":"J Theory Soc Behav"},{"key":"2021012714253008400_awaa313-B89","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1037\/a0013765","article-title":"Diminished self-conscious emotional responding in frontotemporal lobar degeneration patients","volume":"8","author":"Ascher","year":"2008","journal-title":"Emotion"},{"key":"2021012714253008400_awaa313-B90","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1212\/01.WNL.0000091868.28557.B8","article-title":"Left\/right asymmetry of atrophy in semantic dementia: behavioral-cognitive implications","volume":"61","author":"Thompson","year":"2003","journal-title":"Neurology"},{"key":"2021012714253008400_awaa313-B91","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1093\/scan\/nsv013","article-title":"Intrinsic connectivity in the human brain does not reveal networks for \u2018basic\u2019 emotions","volume":"10","author":"Touroutoglou","year":"2015","journal-title":"Soc Cogn Affect Neurosci"},{"key":"2021012714253008400_awaa313-B92","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1037\/a0023853","article-title":"Moving faces, looking places: validation of the Amsterdam Dynamic Facial Expression Set (ADFES)","volume":"11","author":"van der Schalk","year":"2011","journal-title":"Emotion"},{"key":"2021012714253008400_awaa313-B93","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1162\/jocn.2009.21366","article-title":"Neuroimaging support for discrete neural correlates of basic emotions: a voxel-based meta-analysis","volume":"22","author":"Vytal","year":"2010","journal-title":"J Cogn Neurosci"},{"key":"2021012714253008400_awaa313-B94","doi-asserted-by":"crossref","first-page":"E3110","DOI":"10.1073\/pnas.1323342111","article-title":"Neurons in the human amygdala selective for perceived emotion","volume":"111","author":"Wang","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"key":"2021012714253008400_awaa313-B95","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1037\/0012-1649.39.1.114","article-title":"A closer look at preschoolers' freely produced labels for facial expressions","volume":"39","author":"Widen","year":"2003","journal-title":"Dev Psychol"},{"key":"2021012714253008400_awaa313-B96","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1109\/42.906424","article-title":"Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm","volume":"20","author":"Zhang","year":"2001","journal-title":"IEEE Trans Med Imaging"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/143\/12\/3850\/36123520\/awaa313.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/143\/12\/3850\/36123520\/awaa313.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T14:26:14Z","timestamp":1611757574000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article\/143\/12\/3850\/5998326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,22]]},"references-count":95,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020,11,22]]},"published-print":{"date-parts":[[2020,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awaa313","relation":{},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,12,1]]},"published":{"date-parts":[[2020,11,22]]}}}