{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T13:49:19Z","timestamp":1768312159310,"version":"3.49.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T00:00:00Z","timestamp":1605571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81570698"],"award-info":[{"award-number":["81570698"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81520108010"],"award-info":[{"award-number":["81520108010"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81200984"],"award-info":[{"award-number":["81200984"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LY16H070003"],"award-info":[{"award-number":["LY16H070003"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Basic Research Development Program of China","award":["2013CB530900"],"award-info":[{"award-number":["2013CB530900"]}]},{"name":"National Basic Research Development Program of China","award":["2013CB530904"],"award-info":[{"award-number":["2013CB530904"]}]},{"name":"General Medical and Health Project of Zhejiang Province","award":["2018RC004"],"award-info":[{"award-number":["2018RC004"]}]},{"name":"General Medical and Health Project of Zhejiang Province","award":["2019DZ021"],"award-info":[{"award-number":["2019DZ021"]}]},{"name":"General Medical and Health Project of Zhejiang Province","award":["2020RC061"],"award-info":[{"award-number":["2020RC061"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,12]]},"DOI":"10.1093\/brain\/awaa348","type":"journal-article","created":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T19:10:24Z","timestamp":1601147424000},"page":"e1-e1","source":"Crossref","is-referenced-by-count":16,"title":["Assessing the <i>NOTCH2NLC<\/i> GGC expansion in essential tremor patients from eastern China"],"prefix":"10.1093","volume":"144","author":[{"given":"Yaping","family":"Yan","sequence":"first","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanxiao","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"},{"name":"Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luyan","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Congying","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiali","family":"Pu","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinzhen","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baorong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guohua","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"},{"name":"Department of Neurology, The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,11,17]]},"reference":[{"key":"2021021220580441500_awaa348-B1","doi-asserted-by":"crossref","DOI":"10.1093\/brain\/awaa142","article-title":"Essential tremor as the early symptom of NOTCH2NLC gene-related repeat expansion disorder","volume":"143","author":"Chen","year":"2020","journal-title":"Brain"},{"key":"2021021220580441500_awaa348-B2","first-page":"2","article-title":"Consensus statement of the movement disorder society on tremor. Ad Hoc Scientific Committee","volume":"13 (Suppl 3","author":"Deuschl","year":"1998","journal-title":"Mov Disord"},{"key":"2021021220580441500_awaa348-B3","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1002\/acn3.51021","article-title":"Repeat expansion scanning of the NOTCH2NLC gene in patients with multiple system atrophy","volume":"7","author":"Fang","year":"2020","journal-title":"Ann Clin Transl Neurol"},{"key":"2021021220580441500_awaa348-B4","doi-asserted-by":"crossref","first-page":"S92","DOI":"10.1016\/j.parkreldis.2017.07.014","article-title":"The etiology of essential tremor: genes versus environment","volume":"46 (Suppl 1","author":"Hopfner","year":"2018","journal-title":"Parkinsonism Relat Disord"},{"key":"2021021220580441500_awaa348-B5","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.neurobiolaging.2020.01.010","article-title":"Identification of expanded repeats in NOTCH2NLC in neurodegenerative dementias","volume":"89","author":"Jiao","year":"2020","journal-title":"Neurobiol Aging"},{"key":"2021021220580441500_awaa348-B6","doi-asserted-by":"crossref","DOI":"10.1002\/ana.25803","article-title":"NOTCH2NLC GGC repeat expansions are associated with sporadic essential tremor: variable disease expressivity on long-term follow-up","author":"Ng","year":"2020","journal-title":"Ann Neurol"},{"key":"2021021220580441500_awaa348-B7","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/s41588-019-0459-y","article-title":"Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease","volume":"51","author":"Sone","year":"2019","journal-title":"Nat Genet"},{"key":"2021021220580441500_awaa348-B8","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1093\/brain\/awz372","article-title":"Expansion of GGC repeat in the human-specific NOTCH2NLC gene is associated with essential tremor","volume":"143","author":"Sun","year":"2020","journal-title":"Brain"},{"key":"2021021220580441500_awaa348-B9","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.ajhg.2019.05.013","article-title":"Expansion of human-specific GGC repeat in neuronal intranuclear inclusion disease-related disorders","volume":"105","author":"Tian","year":"2019","journal-title":"Am J Hum Genet"},{"key":"2021021220580441500_awaa348-B10","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/brain\/awz404","article-title":"Essential phenotypes of NOTCH2NLC-related repeat expansion disorder","volume":"143","author":"Westenberger","year":"2020","journal-title":"Brain"},{"key":"2021021220580441500_awaa348-B11","doi-asserted-by":"crossref","first-page":"e57","DOI":"10.1093\/brain\/awaa144","article-title":"GGC repeat expansion in NOTCH2NLC is rare in European patients with essential tremor","volume":"143","author":"Yau","year":"2020","journal-title":"Brain"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/144\/1\/e1\/36247712\/awaa348.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/144\/1\/e1\/36247712\/awaa348.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,13]],"date-time":"2021-02-13T01:49:43Z","timestamp":1613180983000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article\/144\/1\/e1\/5986641"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,17]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,11,17]]},"published-print":{"date-parts":[[2021,2,12]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awaa348","relation":{},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,1,1]]},"published":{"date-parts":[[2020,11,17]]}}}