{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T18:02:23Z","timestamp":1770228143076,"version":"3.49.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2022,7,15]],"date-time":"2022-07-15T00:00:00Z","timestamp":1657843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"ZonMw"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,27]]},"abstract":"<jats:p>This scientific commentary refers to \u2018Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline\u2019 by Rabin et al. (https:\/\/doi.org\/10.1093\/brain\/awac178).<\/jats:p>","DOI":"10.1093\/brain\/awac228","type":"journal-article","created":{"date-parts":[[2022,7,18]],"date-time":"2022-07-18T13:19:51Z","timestamp":1658150391000},"page":"2632-2634","source":"Crossref","is-referenced-by-count":18,"title":["Alzheimer\u2019s disease, cerebrovascular disease and dementia: lump, split or integrate?"],"prefix":"10.1093","volume":"145","author":[{"given":"Geert Jan","family":"Biessels","sequence":"first","affiliation":[{"name":"Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht , Utrecht , The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,7,15]]},"reference":[{"key":"2022082719573591100_awac228-B1","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/S1474-4422(16)30029-1","article-title":"Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study","volume":"15","author":"Arvanitakis","year":"2016","journal-title":"Lancet Neurol"},{"key":"2022082719573591100_awac228-B2","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1001\/jama.2015.4669","article-title":"Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis","volume":"313","author":"Ossenkoppele","year":"2015","journal-title":"JAMA"},{"issue":"8","key":"2022082719573591100_awac228-B3","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.1093\/brain\/awac178","article-title":"Cerebral amyloid angiopathy interacts with neuritic amyloid plaques to promote tau and cognitive decline","volume":"145","author":"Rabin","year":"2022","journal-title":"Brain."},{"key":"2022082719573591100_awac228-B4","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/S1474-4422(11)70072-2","article-title":"The projected effect of risk factor reduction on Alzheimer's disease prevalence","volume":"10","author":"Barnes","year":"2011","journal-title":"Lancet Neurol"},{"key":"2022082719573591100_awac228-B5","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1001\/jama.2017.3090","article-title":"Association between midlife vascular risk factors and estimated brain amyloid deposition","volume":"317","author":"Gottesman","year":"2017","journal-title":"JAMA"},{"key":"2022082719573591100_awac228-B6","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/S1474-4422(19)30228-5","article-title":"Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study","volume":"18","author":"Lane","year":"2019","journal-title":"Lancet Neurol"},{"key":"2022082719573591100_awac228-B7","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1056\/NEJMoa0806142","article-title":"Age, neuropathology, and dementia","volume":"360","author":"Savva","year":"2009","journal-title":"N Engl J Med"},{"key":"2022082719573591100_awac228-B8","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1474-4422(12)70291-0","article-title":"Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers","volume":"12","author":"Jack CR","year":"2013","journal-title":"Lancet Neurol"},{"key":"2022082719573591100_awac228-B9","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/s12883-017-0945-8","article-title":"Neurogranin and tau in cerebrospinal fluid and plasma of patients with acute ischemic stroke","volume":"17","author":"De Vos","year":"2017","journal-title":"BMC Neurol"},{"key":"2022082719573591100_awac228-B10","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1161\/STROKEAHA.120.031073","article-title":"Abeta (Amyloid Beta) and tau tangle pathology modifies the association between small vessel disease and cortical microinfarcts","volume":"52","author":"Kapasi","year":"2021","journal-title":"Stroke"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/brain\/advance-article-pdf\/doi\/10.1093\/brain\/awac228\/44920394\/awac228.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/brain\/article-pdf\/145\/8\/2632\/45599732\/awac228.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/brain\/article-pdf\/145\/8\/2632\/45599732\/awac228.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,11]],"date-time":"2023-02-11T21:39:47Z","timestamp":1676151587000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article\/145\/8\/2632\/6644842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,15]]},"references-count":10,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2022,7,15]]},"published-print":{"date-parts":[[2022,8,27]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awac228","relation":{},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,8,1]]},"published":{"date-parts":[[2022,7,15]]}}}