{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T08:13:48Z","timestamp":1781165628596,"version":"3.54.1"},"reference-count":123,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Defense Health Program"},{"name":"Department of Defense Broad Agency Announcement for Extramural Medical Research","award":["W81XWH-14-1-0561"],"award-info":[{"award-number":["W81XWH-14-1-0561"]}]},{"DOI":"10.13039\/100000005","name":"Department of Defense","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute of Neurological Disorders And Stroke of the National Institutes of Health","award":["R21NS099789"],"award-info":[{"award-number":["R21NS099789"]}]},{"DOI":"10.13039\/100001380","name":"William K. Warren Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001380","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["R01MH123652"],"award-info":[{"award-number":["R01MH123652"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["P20GM121312"],"award-info":[{"award-number":["P20GM121312"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Adult Translational Research Unit"},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1TR001436"],"award-info":[{"award-number":["UL1TR001436"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Research Computing Center at the Medical College of Wisconsin"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The neurotrophic herpes virus cytomegalovirus is a known cause of neuropathology in utero and in immunocompromised populations. Cytomegalovirus is reactivated by stress and inflammation, possibly explaining the emerging evidence linking it to subtle brain changes in the context of more minor disturbances of immune function. Even mild forms of traumatic brain injury, including sport-related concussion, are major physiological stressors that produce neuroinflammation. In theory, concussion could predispose to the reactivation of cytomegalovirus and amplify the effects of physical injury on brain structure. However, to our knowledge this hypothesis remains untested.<\/jats:p>\n               <jats:p>This study evaluated the effect of cytomegalovirus serostatus on white and grey matter structure in a prospective study of athletes with concussion and matched contact-sport controls.<\/jats:p>\n               <jats:p>Athletes who sustained concussion (n = 88) completed MRI at 1, 8, 15 and 45 days post-injury; matched uninjured athletes (n = 73) completed similar visits. Cytomegalovirus serostatus was determined by measuring serum IgG antibodies (n = 30 concussed athletes and n = 21 controls were seropositive). Inverse probability of treatment weighting was used to adjust for confounding factors between athletes with and without cytomegalovirus. White matter microstructure was assessed using diffusion kurtosis imaging metrics in regions previously shown to be sensitive to concussion. T1-weighted images were used to quantify mean cortical thickness and total surface area. Concussion-related symptoms, psychological distress, and serum concentration of C-reactive protein at 1 day post-injury were included as exploratory outcomes. Planned contrasts compared the effects of cytomegalovirus seropositivity in athletes with concussion and controls, separately.<\/jats:p>\n               <jats:p>There was a significant effect of cytomegalovirus on axial and radial kurtosis in athletes with concussion but not controls. Cytomegalovirus positive athletes with concussion showed greater axial (P = 0.007, d = 0.44) and radial (P = 0.010, d = 0.41) kurtosis than cytomegalovirus negative athletes with concussion. Similarly, there was a significant association of cytomegalovirus with cortical thickness in athletes with concussion but not controls. Cytomegalovirus positive athletes with concussion had reduced mean cortical thickness of the right hemisphere (P = 0.009, d = 0.42) compared with cytomegalovirus negative athletes with concussion and showed a similar trend for the left hemisphere (P = 0.036, d = 0.33). There was no significant effect of cytomegalovirus on kurtosis fractional anisotropy, surface area, symptoms and C-reactive protein.<\/jats:p>\n               <jats:p>The results raise the possibility that cytomegalovirus infection contributes to structural brain abnormalities in the aftermath of concussion perhaps via an amplification of concussion-associated neuroinflammation. More work is needed to identify the biological pathways underlying this process and to clarify the clinical relevance of this putative viral effect.<\/jats:p>","DOI":"10.1093\/brain\/awad126","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T11:37:52Z","timestamp":1681817872000},"page":"4262-4273","source":"Crossref","is-referenced-by-count":14,"title":["The effects of cytomegalovirus on brain structure following sport-related concussion"],"prefix":"10.1093","volume":"146","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8143-182X","authenticated-orcid":false,"given":"Jonathan","family":"Savitz","sequence":"first","affiliation":[{"name":"Laureate Institute for Brain Research , Tulsa, OK 74136 , USA"},{"name":"Oxley College of Health Sciences, The University of Tulsa , Tulsa, OK 74119 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryna D","family":"Goeckner","sequence":"additional","affiliation":[{"name":"Department of Biophysics, Medical College of Wisconsin , Milwaukee, WI 53226 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart N","family":"Ford","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Physiology, Oklahoma State University Center for Health Sciences , Tulsa, OK 74107 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Kent Teague","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, The University of Oklahoma School of Community Medicine , Tulsa, OK 74135 , USA"},{"name":"Department of Surgery, The University of Oklahoma School of Community Medicine , Tulsa, OK 74135 , USA"},{"name":"Department of Pharmaceutical Sciences, University of Oklahoma College of Pharmacy , Tulsa, OK 74135 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haixia","family":"Zheng","sequence":"additional","affiliation":[{"name":"Laureate Institute for Brain Research , Tulsa, OK 74136 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaroslaw","family":"Harezlak","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University , Bloomington, IN 47405 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3608-2792","authenticated-orcid":false,"given":"Rebekah","family":"Mannix","sequence":"additional","affiliation":[{"name":"Division of Emergency Medicine, Boston Children\u2019s Hospital , Boston, MA 02115 , USA"},{"name":"Department of Pediatrics, Harvard Medical School , Boston, MA 02115 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Tugan Muftuler","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin , Milwaukee, WI 53226 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin L","family":"Brett","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin , Milwaukee, WI 53226 , USA"},{"name":"Department of Neurology, Medical College of Wisconsin , Milwaukee, WI 53226 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A","family":"McCrea","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin , Milwaukee, WI 53226 , USA"},{"name":"Department of Neurology, Medical College of Wisconsin , Milwaukee, WI 53226 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4495-2754","authenticated-orcid":false,"given":"Timothy B","family":"Meier","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical College of Wisconsin , Milwaukee, WI 53226 , USA"},{"name":"Department of Biomedical Engineering, Medical College of Wisconsin , Milwaukee, WI 53226 , USA"},{"name":"Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin , Milwaukee, WI 53226 , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,4,18]]},"reference":[{"key":"2024041801131473200_awad126-B1","doi-asserted-by":"crossref","first-page":"e408","DOI":"10.1093\/cid\/ciaa1168","article-title":"Changes in cytomegalovirus seroprevalence among U.S. Children aged 1-5 years: The national health and nutrition examination surveys","volume":"72","author":"Petersen","year":"2021","journal-title":"Clin Infect Dis."},{"key":"2024041801131473200_awad126-B2","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/rmv.475","article-title":"Neuropathogenesis in cytomegalovirus infection: Indication of the mechanisms using mouse models","volume":"15","author":"Tsutsui","year":"2005","journal-title":"Rev Med Virol"},{"key":"2024041801131473200_awad126-B3","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1093\/infdis\/162.6.1252","article-title":"Cytomegalovirus in the brain: In vitro infection of human brain-derived cells","volume":"162","author":"Poland","year":"1990","journal-title":"J Infect Dis"},{"key":"2024041801131473200_awad126-B4","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/1742-2094-9-95","article-title":"Infection and upregulation of proinflammatory cytokines in human brain vascular pericytes by human cytomegalovirus","volume":"9","author":"Alcendor","year":"2012","journal-title":"J Neuroinflammation"},{"key":"2024041801131473200_awad126-B5","doi-asserted-by":"crossref","first-page":"5661","DOI":"10.1128\/JVI.72.7.5661-5668.1998","article-title":"Human cytomegalovirus persistently infects aortic endothelial cells","volume":"72","author":"Fish","year":"1998","journal-title":"J Virol"},{"key":"2024041801131473200_awad126-B6","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1006\/viro.2000.0367","article-title":"A novel link between stress and human cytomegalovirus (HCMV) infection: Sympathetic hyperactivity stimulates HCMV activation","volume":"272","author":"Prosch","year":"2000","journal-title":"Virology"},{"key":"2024041801131473200_awad126-B7","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1097\/00007890-199904270-00011","article-title":"Intraoperative hypothermia is an independent risk factor for early cytomegalovirus infection in liver transplant recipients","volume":"67","author":"Paterson","year":"1999","journal-title":"Transplantation"},{"key":"2024041801131473200_awad126-B8","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.bbi.2014.01.012","article-title":"Consistent associations between measures of psychological stress and CMV antibody levels in a large occupational sample","volume":"38","author":"Rector","year":"2014","journal-title":"Brain Behav Immun"},{"key":"2024041801131473200_awad126-B9","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/S0140-6736(94)91116-9","article-title":"Cytomegalovirus reactivation and tumour necrosis factor","volume":"343","author":"Docke","year":"1994","journal-title":"Lancet"},{"key":"2024041801131473200_awad126-B10","doi-asserted-by":"crossref","first-page":"20039","DOI":"10.1073\/pnas.1014509107","article-title":"Experimental human cytomegalovirus latency in CD14 + monocytes","volume":"107","author":"Hargett","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"2024041801131473200_awad126-B11","doi-asserted-by":"crossref","first-page":"3154","DOI":"10.1172\/JCI119871","article-title":"Interferon-gamma and tumor necrosis factor-alpha specifically induce formation of cytomegalovirus-permissive monocyte-derived macrophages that are refractory to the antiviral activity of these cytokines","volume":"100","author":"Soderberg-Naucler","year":"1997","journal-title":"J Clin Invest"},{"key":"2024041801131473200_awad126-B12","doi-asserted-by":"crossref","first-page":"e20190554","DOI":"10.1084\/jem.20190554","article-title":"\u03b22-adrenergic signals downregulate the innate immune response and reduce host resistance to viral infection","volume":"217(4)","author":"Wieduwild","year":"2020","journal-title":"J Exp Med"},{"issue":"Pt 11","key":"2024041801131473200_awad126-B13","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1099\/0022-1317-74-11-2333","article-title":"Tumour necrosis factor alpha stimulates the activity of the human cytomegalovirus major immediate early enhancer\/promoter in immature monocytic cells","volume":"74","author":"Stein","year":"1993","journal-title":"J Gen Virol"},{"key":"2024041801131473200_awad126-B14","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1099\/jgv.0.000407","article-title":"Transplant-induced reactivation of murine cytomegalovirus immediate early gene expression is associated with recruitment of NF-kappaB and AP-1 to the major immediate early promoter","volume":"97","author":"Liu","year":"2016","journal-title":"J Gen Virol"},{"key":"2024041801131473200_awad126-B15","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/s41579-021-00582-z","article-title":"Pathogenesis of human cytomegalovirus in the immunocompromised host","volume":"19","author":"Griffiths","year":"2021","journal-title":"Nat Rev Microbiol"},{"key":"2024041801131473200_awad126-B16","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1146\/annurev.me.42.020191.000425","article-title":"Latency of the human herpesviruses","volume":"42","author":"Croen","year":"1991","journal-title":"Annu Rev Med"},{"key":"2024041801131473200_awad126-B17","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1001\/jama.2008.697","article-title":"Cytomegalovirus reactivation in critically ill immunocompetent patients","volume":"300","author":"Limaye","year":"2008","journal-title":"Jama"},{"issue":"Suppl 1","key":"2024041801131473200_awad126-B18","doi-asserted-by":"crossref","first-page":"S94","DOI":"10.1093\/infdis\/jiz638","article-title":"Current understanding of cytomegalovirus reactivation in critical illness","volume":"221","author":"Imlay","year":"2020","journal-title":"J Infect Dis"},{"key":"2024041801131473200_awad126-B19","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/472978","article-title":"Human cytomegalovirus and autoimmune disease","volume":"2014","author":"Halenius","year":"2014","journal-title":"Biomed Res Int"},{"key":"2024041801131473200_awad126-B20","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/s41598-017-00645-3","article-title":"Cytomegalovirus infection exacerbates autoimmune mediated neuroinflammation","volume":"7","author":"Vanheusden","year":"2017","journal-title":"Sci Rep"},{"key":"2024041801131473200_awad126-B21","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcv.2021.104849","article-title":"Subclinical CMV viremia is associated with increased nosocomial infections and prolonged hospitalization in patients with systemic autoimmune diseases","volume":"140","author":"Maksimowicz-McKinnon","year":"2021","journal-title":"J Clin Virol"},{"key":"2024041801131473200_awad126-B22","doi-asserted-by":"crossref","first-page":"260","DOI":"10.3390\/v13020260","article-title":"Human cytomegalovirus and autoimmune diseases: Where are we?","volume":"13","author":"Gugliesi","year":"2021","journal-title":"Viruses"},{"issue":"1\u20133","key":"2024041801131473200_awad126-B23","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0047-6374(00)00210-4","article-title":"Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: The Swedish longitudinal OCTO immune study","volume":"121","author":"Olsson","year":"2001","journal-title":"Mech Ageing Dev"},{"issue":"2\u20133","key":"2024041801131473200_awad126-B24","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0531-5565(01)00212-1","article-title":"Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: The Swedish NONA immune study","volume":"37","author":"Wikby","year":"2002","journal-title":"Exp Gerontol"},{"key":"2024041801131473200_awad126-B25","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/acel.12059","article-title":"Cytomegalovirus infection is associated with increased mortality in the older population","volume":"12","author":"Savva","year":"2013","journal-title":"Aging Cell"},{"key":"2024041801131473200_awad126-B26","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1001\/jama.2009.4","article-title":"Cytomegalovirus antibody level and mortality among community-dwelling older adults with stable cardiovascular disease","volume":"301","author":"Strandberg","year":"2009","journal-title":"Jama"},{"key":"2024041801131473200_awad126-B27","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1093\/schbul\/sbac036","article-title":"Cytomegalovirus infection associated with smaller total cortical surface area in schizophrenia Spectrum disorders","volume":"48","author":"Andreou","year":"2022","journal-title":"Schizophr Bull"},{"key":"2024041801131473200_awad126-B28","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.pnpbp.2013.09.003","article-title":"Cytomegalovirus seropositivity and serointensity are associated with hippocampal volume and verbal memory in schizophrenia and bipolar disorder","volume":"48","author":"Houenou","year":"2014","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"2024041801131473200_awad126-B29","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.bbi.2021.05.009","article-title":"Cytomegalovirus infection associated with smaller dentate gyrus in men with severe mental illness","volume":"96","author":"Andreou","year":"2021","journal-title":"Brain Behav Immun"},{"key":"2024041801131473200_awad126-B30","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1038\/s41386-021-00971-1","article-title":"Replicable association between human cytomegalovirus infection and reduced white matter fractional anisotropy in major depressive disorder","volume":"46","author":"Zheng","year":"2021","journal-title":"Neuropsychopharmacology"},{"key":"2024041801131473200_awad126-B31","doi-asserted-by":"crossref","first-page":"4234","DOI":"10.1038\/s41380-020-00932-y","article-title":"A hidden menace? Cytomegalovirus infection is associated with reduced cortical grey matter volume in major depressive disorder","volume":"26","author":"Zheng","year":"2021","journal-title":"Mol Psychiatry"},{"key":"2024041801131473200_awad126-B32","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/s41398-021-01558-6","article-title":"Association between cytomegalovirus infection, reduced grey matter volume, and resting-state functional hypoconnectivity in major depressive disorder: A replication and extension","volume":"11","author":"Zheng","year":"2021","journal-title":"Transl Psychiatry"},{"key":"2024041801131473200_awad126-B33","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1080\/02699052.2019.1631488","article-title":"Autonomic nervous system dysfunction in mild traumatic brain injury: A review of related pathophysiology and symptoms","volume":"33","author":"Purkayastha","year":"2019","journal-title":"Brain Inj"},{"issue":"Pt A","key":"2024041801131473200_awad126-B34","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ijpsycho.2017.11.016","article-title":"An anatomical and physiological basis for the cardiovascular autonomic nervous system consequences of sport-related brain injury","volume":"132","author":"La Fountaine","year":"2018","journal-title":"Int J Psychophysiol"},{"key":"2024041801131473200_awad126-B35","doi-asserted-by":"crossref","first-page":"3795","DOI":"10.2741\/3489","article-title":"Systemic inflammatory response following acute traumatic brain injury","volume":"14","author":"Lu","year":"2009","journal-title":"Front Biosci."},{"key":"2024041801131473200_awad126-B36","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.ncl.2017.03.011","article-title":"Pathophysiology of sports-related concussion","volume":"35","author":"Steenerson","year":"2017","journal-title":"Neurol Clin"},{"key":"2024041801131473200_awad126-B37","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.biopsych.2021.05.021","article-title":"The kynurenine pathway in traumatic brain injury: Implications for psychiatric outcomes","volume":"91","author":"Meier","year":"2022","journal-title":"Biol Psychiatry"},{"key":"2024041801131473200_awad126-B38","doi-asserted-by":"crossref","first-page":"E10","DOI":"10.3171\/2021.11.FOCUS21586","article-title":"Central nervous system injury-induced immune suppression","volume":"52","author":"Sribnick","year":"2022","journal-title":"Neurosurg Focus"},{"key":"2024041801131473200_awad126-B39","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3389\/fneur.2015.00235","article-title":"Traumatic brain injury and peripheral immune suppression: Primer and prospectus","volume":"6","author":"Hazeldine","year":"2015","journal-title":"Front Neurol"},{"key":"2024041801131473200_awad126-B40","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.bbi.2019.04.034","article-title":"Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems","volume":"79","author":"Sharma","year":"2019","journal-title":"Brain Behav Immun"},{"key":"2024041801131473200_awad126-B41","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1089\/neu.2020.6993","article-title":"Serial diffusion kurtosis magnetic resonance imaging study during acute, subacute, and recovery periods after sport-related concussion","volume":"37","author":"Muftuler","year":"2020","journal-title":"J Neurotrauma"},{"key":"2024041801131473200_awad126-B42","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1093\/brain\/awaa447","article-title":"Diffuse axonal injury has a characteristic multidimensional MRI signature in the human brain","volume":"144","author":"Benjamini","year":"2021","journal-title":"Brain"},{"key":"2024041801131473200_awad126-B43","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1136\/bjsports-2016-097447","article-title":"Role of advanced neuroimaging, fluid biomarkers and genetic testing in the assessment of sport-related concussion: A systematic review","volume":"51","author":"McCrea","year":"2017","journal-title":"Br J Sports Med."},{"key":"2024041801131473200_awad126-B44","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1002\/ana.25725","article-title":"A prospective study of acute blood-based biomarkers for sport-related concussion","volume":"87","author":"Meier","year":"2020","journal-title":"Ann Neurol."},{"key":"2024041801131473200_awad126-B45","first-page":"21","article-title":"Four factor index of social status","volume":"8","author":"Hollingshead","year":"2011","journal-title":"Yale Journal of Sociology"},{"key":"2024041801131473200_awad126-B46","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1016\/S1053-8119(03)00336-7","article-title":"How to correct susceptibility distortions in spin-echo echo-planar images: Application to diffusion tensor imaging","volume":"20","author":"Andersson","year":"2003","journal-title":"NeuroImage"},{"key":"2024041801131473200_awad126-B47","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/j.neuroimage.2015.10.019","article-title":"An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging","volume":"125","author":"Andersson","year":"2016","journal-title":"NeuroImage"},{"key":"2024041801131473200_awad126-B48","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1002\/nbm.1518","article-title":"MRI Quantification of non-Gaussian water diffusion by kurtosis analysis","volume":"23","author":"Jensen","year":"2010","journal-title":"NMR Biomed"},{"key":"2024041801131473200_awad126-B49","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1002\/mrm.20508","article-title":"Diffusional kurtosis imaging: The quantification of non-Gaussian water diffusion by means of magnetic resonance imaging","volume":"53","author":"Jensen","year":"2005","journal-title":"Magn Reson Med"},{"key":"2024041801131473200_awad126-B50","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1002\/mrm.25165","article-title":"REKINDLE: Robust extraction of kurtosis INDices with linear estimation","volume":"73","author":"Tax","year":"2015","journal-title":"Magn Reson Med"},{"key":"2024041801131473200_awad126-B51","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1016\/j.neuroimage.2006.02.024","article-title":"Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data","volume":"31","author":"Smith","year":"2006","journal-title":"Neuroimage"},{"key":"2024041801131473200_awad126-B52","doi-asserted-by":"crossref","first-page":"11050","DOI":"10.1073\/pnas.200033797","article-title":"Measuring the thickness of the human cerebral cortex from magnetic resonance images","volume":"97","author":"Fischl","year":"2000","journal-title":"Proc Natl Acad Sci USA."},{"key":"2024041801131473200_awad126-B53","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0896-6273(02)00569-X","article-title":"Whole brain segmentation: Automated labeling of neuroanatomical structures in the human brain","volume":"33","author":"Fischl","year":"2002","journal-title":"Neuron"},{"key":"2024041801131473200_awad126-B54","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1016\/j.neuroimage.2012.02.084","article-title":"Within-subject template estimation for unbiased longitudinal image analysis","volume":"61","author":"Reuter","year":"2012","journal-title":"Neuroimage"},{"key":"2024041801131473200_awad126-B55","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/j.neuroimage.2006.01.021","article-title":"An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest","volume":"31","author":"Desikan","year":"2006","journal-title":"Neuroimage"},{"key":"2024041801131473200_awad126-B56","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1093\/cercor\/bhg087","article-title":"Automatically parcellating the human cerebral cortex","volume":"14","author":"Fischl","year":"2004","journal-title":"Cereb Cortex"},{"key":"2024041801131473200_awad126-B57","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.neuroimage.2013.05.007","article-title":"Brain morphometry reproducibility in multi-center 3 T MRI studies: A comparison of cross-sectional and longitudinal segmentations","volume":"83","author":"Jovicich","year":"2013","journal-title":"Neuroimage"},{"key":"2024041801131473200_awad126-B58","doi-asserted-by":"crossref","first-page":"379","DOI":"10.3389\/fnins.2015.00379","article-title":"A comparison of FreeSurfer-generated data with and without manual intervention","volume":"9","author":"McCarthy","year":"2015","journal-title":"Front Neurosci"},{"key":"2024041801131473200_awad126-B59","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1007\/s00330-018-5710-x","article-title":"Repeatability and reproducibility of FreeSurfer, FSL-SIENAX and SPM brain volumetric measurements and the effect of lesion filling in multiple sclerosis","volume":"29","author":"Guo","year":"2019","journal-title":"Eur Radiol"},{"key":"2024041801131473200_awad126-B60","doi-asserted-by":"crossref","first-page":"3661","DOI":"10.1002\/sim.6607","article-title":"Moving towards best practice when using inverse probability of treatment weighting (IPTW) using the propensity score to estimate causal treatment effects in observational studies","volume":"34","author":"Austin","year":"2015","journal-title":"Stat Med"},{"key":"2024041801131473200_awad126-B61","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1086\/508173","article-title":"Seroprevalence of cytomegalovirus infection in the United States, 1988-1994","volume":"43","author":"Staras","year":"2006","journal-title":"Clin Infect Dis"},{"key":"2024041801131473200_awad126-B62","doi-asserted-by":"crossref","first-page":"W26","DOI":"10.2214\/AJR.13.11365","article-title":"Diffusion kurtosis imaging: An emerging technique for evaluating the microstructural environment of the brain","volume":"202","author":"Steven","year":"2014","journal-title":"AJR Am J Roentgenol"},{"key":"2024041801131473200_awad126-B63","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/nbm.1020","article-title":"Three-dimensional characterization of non-Gaussian water diffusion in humans using diffusion kurtosis imaging","volume":"19","author":"Lu","year":"2006","journal-title":"NMR Biomed"},{"key":"2024041801131473200_awad126-B64","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jmr.2018.04.016","article-title":"Diffusion MRI in acute nervous system injury","volume":"292","author":"Budde","year":"2018","journal-title":"J Magn Reson"},{"key":"2024041801131473200_awad126-B65","article-title":"Combined application of quantitative susceptibility mapping and diffusion kurtosis imaging techniques to investigate the effect of iron deposition on microstructural changes in the brain in Parkinson's disease","volume":"14","author":"Yang","year":"2022","journal-title":"Front Aging Neurosci."},{"key":"2024041801131473200_awad126-B66","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2019.101669","article-title":"Dynamic changes in hippocampal diffusion and kurtosis metrics following experimental mTBI correlate with glial reactivity","volume":"21","author":"Braeckman","year":"2019","journal-title":"Neuroimage Clin"},{"key":"2024041801131473200_awad126-B67","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1089\/neu.2016.4569","article-title":"Repetitive model of mild traumatic brain injury produces cortical abnormalities detectable by magnetic resonance diffusion imaging, histopathology, and behavior","volume":"34","author":"Yu","year":"2017","journal-title":"J Neurotrauma"},{"key":"2024041801131473200_awad126-B68","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.3174\/ajnr.A5737","article-title":"Longitudinal microstructural changes in traumatic brain injury in rats: A diffusional kurtosis imaging, histology, and behavior study","volume":"39","author":"Wang","year":"2018","journal-title":"AJNR Am J Neuroradiol"},{"key":"2024041801131473200_awad126-B69","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.neuroimage.2015.10.052","article-title":"Diffusion kurtosis imaging probes cortical alterations and white matter pathology following cuprizone induced demyelination and spontaneous remyelination","volume":"125","author":"Guglielmetti","year":"2016","journal-title":"Neuroimage"},{"key":"2024041801131473200_awad126-B70","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/s11682-012-9156-5","article-title":"A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury","volume":"6","author":"Shenton","year":"2012","journal-title":"Brain Imaging Behav"},{"key":"2024041801131473200_awad126-B71","doi-asserted-by":"crossref","first-page":"4998","DOI":"10.1002\/hbm.24340","article-title":"Genetic influences on neonatal cortical thickness and surface area","volume":"39","author":"Jha","year":"2018","journal-title":"Hum Brain Mapp"},{"key":"2024041801131473200_awad126-B72","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1093\/cercor\/bhp026","article-title":"Distinct genetic influences on cortical surface area and cortical thickness","volume":"19","author":"Panizzon","year":"2009","journal-title":"Cereb Cortex"},{"key":"2024041801131473200_awad126-B73","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1126\/science.3291116","article-title":"Specification of cerebral cortical areas","volume":"241","author":"Rakic","year":"1988","journal-title":"Science"},{"key":"2024041801131473200_awad126-B74","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/j.biopsych.2004.08.022","article-title":"Cellular changes in the postmortem hippocampus in major depression","volume":"56","author":"Stockmeier","year":"2004","journal-title":"Biol Psychiatry"},{"key":"2024041801131473200_awad126-B75","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.bbi.2015.11.003","article-title":"Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder","volume":"53","author":"Meier","year":"2016","journal-title":"Brain Behav Immun"},{"key":"2024041801131473200_awad126-B76","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s00406-021-01237-z","article-title":"Increased peripheral inflammation in schizophrenia is associated with worse cognitive performance and related cortical thickness reductions","volume":"271","author":"North","year":"2021","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"2024041801131473200_awad126-B77","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.612471","article-title":"The role of peripheral inflammation in clinical outcome and brain imaging abnormalities in psychosis: A systematic review","volume":"12","author":"Kose","year":"2021","journal-title":"Front Psychiatry."},{"key":"2024041801131473200_awad126-B78","doi-asserted-by":"crossref","first-page":"e147329","DOI":"10.1172\/JCI147329","article-title":"Long-term microstructure and cerebral blood flow changes in patients recovered from COVID-19 without neurological manifestations","volume":"131","author":"Qin","year":"2021","journal-title":"J Clin Invest"},{"key":"2024041801131473200_awad126-B79","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.bbi.2020.11.024","article-title":"Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder","volume":"92","author":"Green","year":"2021","journal-title":"Brain Behav Immun"},{"key":"2024041801131473200_awad126-B80","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.bbi.2016.10.019","article-title":"Immunometabolic dysregulation is associated with reduced cortical thickness of the anterior cingulate cortex","volume":"60","author":"van Velzen","year":"2017","journal-title":"Brain Behav Immun"},{"key":"2024041801131473200_awad126-B81","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.3389\/fimmu.2018.02230","article-title":"C-Reactive protein: Higher during acute psychotic episodes and related to cortical thickness in schizophrenia and healthy controls","volume":"9","author":"Jacomb","year":"2018","journal-title":"Front Immunol"},{"key":"2024041801131473200_awad126-B82","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.2050","article-title":"Patterns of cortical grey matter thickness reduction in multiple sclerosis","volume":"11","author":"Fujimori","year":"2021","journal-title":"Brain Behav"},{"key":"2024041801131473200_awad126-B83","doi-asserted-by":"crossref","first-page":"e1074","DOI":"10.1212\/NXI.0000000000001074","article-title":"Cortical thickness and Serum NfL explain cognitive dysfunction in newly diagnosed patients with multiple sclerosis","volume":"8","author":"Cruz-Gomez","year":"2021","journal-title":"Neurol Neuroimmunol Neuroinflamm"},{"key":"2024041801131473200_awad126-B84","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.nicl.2012.11.009","article-title":"Regional cortical thickness in relapsing remitting multiple sclerosis: A multi-center study","volume":"2","author":"Narayana","year":"2013","journal-title":"Neuroimage Clin"},{"issue":"Pt 1","key":"2024041801131473200_awad126-B85","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1093\/brain\/awv337","article-title":"Cortical atrophy patterns in multiple sclerosis are non-random and clinically relevant","volume":"139","author":"Steenwijk","year":"2016","journal-title":"Brain"},{"key":"2024041801131473200_awad126-B86","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1002\/hbm.25408","article-title":"Impact of HIV-infection on human somatosensory processing, spontaneous cortical activity, and cortical thickness: A multimodal neuroimaging approach","volume":"42","author":"Casagrande","year":"2021","journal-title":"Hum Brain Mapp"},{"key":"2024041801131473200_awad126-B87","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000025403","article-title":"Effects of perinatal HIV-infection on the cortical thickness and subcortical grey matter volumes in young adulthood","volume":"100","author":"Ruiz-Saez","year":"2021","journal-title":"Medicine (Baltimore)."},{"key":"2024041801131473200_awad126-B88","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1093\/cid\/ciy362","article-title":"Longitudinal trajectories of brain volume and cortical thickness in treated and untreated primary human immunodeficiency virus infection","volume":"67","author":"Sanford","year":"2018","journal-title":"Clin Infect Dis."},{"key":"2024041801131473200_awad126-B89","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/infdis\/jiu417","article-title":"Cytomegalovirus coinfection is associated with an increased risk of severe non-AIDS-defining events in a large cohort of HIV-infected patients","volume":"211","author":"Lichtner","year":"2015","journal-title":"J Infect Dis"},{"key":"2024041801131473200_awad126-B90","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1097\/COH.0000000000000678","article-title":"Clinical consequences of asymptomatic cytomegalovirus in treated human immunodeficency virus infection","volume":"16","author":"Schnittman","year":"2021","journal-title":"Curr Opin HIV AIDS"},{"key":"2024041801131473200_awad126-B91","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1093\/infdis\/jiac020","article-title":"Cytomegalovirus latent infection is associated with an increased risk of COVID-19-related hospitalization","volume":"226","author":"Alanio","year":"2022","journal-title":"J Infect Dis"},{"key":"2024041801131473200_awad126-B92","doi-asserted-by":"crossref","first-page":"815","DOI":"10.4093\/dmj.2018.0167","article-title":"Impact of cytomegalovirus disease on new-onset type 2 diabetes Mellitus: Population-based matched case-control cohort study","volume":"43","author":"Yoo","year":"2019","journal-title":"Diabetes Metab J"},{"key":"2024041801131473200_awad126-B93","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1007\/s00125-022-05704-7","article-title":"Health impact of seven herpesviruses on (pre)diabetes incidence and HbA1c: Results from the KORA cohort","volume":"65","author":"Woelfle","year":"2022","journal-title":"Diabetologia"},{"key":"2024041801131473200_awad126-B94","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/aje\/kwq177","article-title":"Cytomegalovirus antibody levels, inflammation, and mortality among elderly latinos over 9 years of follow-up","volume":"172","author":"Roberts","year":"2010","journal-title":"Am J Epidemiol"},{"key":"2024041801131473200_awad126-B95","doi-asserted-by":"crossref","first-page":"e005025","DOI":"10.1161\/JAHA.116.005025","article-title":"Cytomegalovirus infection and relative risk of cardiovascular disease (ischemic heart disease, stroke, and cardiovascular death): A meta-analysis of prospective studies up to 2016","volume":"6","author":"Wang","year":"2017","journal-title":"J Am Heart Assoc"},{"key":"2024041801131473200_awad126-B96","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1097\/QAD.0000000000002484","article-title":"Presence of asymptomatic cytomegalovirus and epstein\u2013barr virus DNA in blood of persons with HIV starting antiretroviral therapy is associated with non-AIDS clinical events","volume":"34","author":"Gianella","year":"2020","journal-title":"AIDS"},{"key":"2024041801131473200_awad126-B97","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.3389\/fneur.2019.01345","article-title":"The association between persistent white-matter abnormalities and repeat injury after sport-related concussion","volume":"10","author":"Brett","year":"2020","journal-title":"Front Neurol"},{"key":"2024041801131473200_awad126-B98","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1089\/neu.2012.2399","article-title":"Repeated mild traumatic brain injury: Mechanisms of cerebral vulnerability","volume":"30","author":"Prins","year":"2013","journal-title":"J Neurotrauma"},{"key":"2024041801131473200_awad126-B99","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1136\/bjsports-2016-097464","article-title":"What is the physiological time to recovery after concussion? A systematic review","volume":"51","author":"Kamins","year":"2017","journal-title":"Br J Sports Med."},{"key":"2024041801131473200_awad126-B100","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1089\/neu.2015.3919","article-title":"Thinner Cortex in collegiate football players with, but not without, a self-reported history of concussion","volume":"33","author":"Meier","year":"2016","journal-title":"J Neurotrauma."},{"key":"2024041801131473200_awad126-B101","doi-asserted-by":"crossref","first-page":"5331","DOI":"10.1093\/cercor\/bhab161","article-title":"White and grey matter abnormalities in Australian footballers with a history of sports-related concussion: An MRI study","volume":"31","author":"Major","year":"2021","journal-title":"Cereb Cortex"},{"key":"2024041801131473200_awad126-B102","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1007\/s00429-015-1012-0","article-title":"Frontotemporal correlates of impulsivity and machine learning in retired professional athletes with a history of multiple concussions","volume":"221","author":"Goswami","year":"2016","journal-title":"Brain Structure and Function"},{"key":"2024041801131473200_awad126-B103","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.nicl.2018.05.014","article-title":"The relationship between brain atrophy and cognitive-behavioural symptoms in retired Canadian football players with multiple concussions","volume":"19","author":"Misquitta","year":"2018","journal-title":"NeuroImage: Clinical"},{"key":"2024041801131473200_awad126-B104","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.neurobiolaging.2017.09.009","article-title":"Thinner cortex in patients with subjective cognitive decline is associated with steeper decline of memory","volume":"61","author":"Verfaillie","year":"2018","journal-title":"Neurobiol Aging"},{"key":"2024041801131473200_awad126-B105","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.arr.2016.10.001","article-title":"Structural neuroimaging in preclinical dementia: From microstructural deficits and grey matter atrophy to macroscale connectomic changes","volume":"35","author":"Mak","year":"2017","journal-title":"Ageing Res Rev"},{"key":"2024041801131473200_awad126-B106","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.neuron.2022.12.029","article-title":"Virus exposure and neurodegenerative disease risk across national biobanks","volume":"111","author":"Levine","year":"2023","journal-title":"Neuron"},{"issue":"1\u20132","key":"2024041801131473200_awad126-B107","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cell.2014.12.020","article-title":"Variation in the human immune system is largely driven by non-heritable influences","volume":"160","author":"Brodin","year":"2015","journal-title":"Cell"},{"key":"2024041801131473200_awad126-B108","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.4049\/jimmunol.1800171","article-title":"Cytomegalovirus: Shape-shifting the immune system","volume":"200","author":"Picarda","year":"2018","journal-title":"J Immunol"},{"key":"2024041801131473200_awad126-B109","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/7854_2022_361","article-title":"Effect of cytomegalovirus infection on the central nervous system: Implications for psychiatric disorders","volume":"61","author":"Zheng","year":"2023","journal-title":"Curr Top Behav Neurosci"},{"key":"2024041801131473200_awad126-B110","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1136\/bjsports-2017-097791","article-title":"A systematic review of potential long-term effects of sport-related concussion","volume":"51","author":"Manley","year":"2017","journal-title":"Br J Sports Med."},{"key":"2024041801131473200_awad126-B111","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1097\/HTR.0000000000000767","article-title":"Short-Term neurologic manifestations of repetitive head impacts among athletes: A scoping review","volume":"37","author":"Stephen","year":"2022","journal-title":"J Head Trauma Rehabil"},{"key":"2024041801131473200_awad126-B112","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2022.938163","article-title":"Applying the bradford hill criteria for causation to repetitive head impacts and chronic traumatic encephalopathy","volume":"13","author":"Nowinski","year":"2022","journal-title":"Front Neurol"},{"key":"2024041801131473200_awad126-B113","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1055\/s-0040-1713632","article-title":"The neuropathology of chronic traumatic encephalopathy: The Status of the literature","volume":"40","author":"McKee","year":"2020","journal-title":"Semin Neurol"},{"key":"2024041801131473200_awad126-B114","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1093\/brain\/aws322","article-title":"Inflammation and white matter degeneration persist for years after a single traumatic brain injury","volume":"136","author":"Johnson","year":"2013","journal-title":"Brain"},{"key":"2024041801131473200_awad126-B115","doi-asserted-by":"crossref","first-page":"1892","DOI":"10.1089\/neu.2019.6850","article-title":"Post-Acute cortical thickness in children with mild traumatic brain injury versus orthopedic injury","volume":"37","author":"Ware","year":"2020","journal-title":"J Neurotrauma"},{"key":"2024041801131473200_awad126-B116","doi-asserted-by":"crossref","first-page":"e516","DOI":"10.1212\/WNL.0000000000201470","article-title":"Prospective study of gray matter atrophy following pediatric mild traumatic brain injury","volume":"100","author":"Mayer","year":"2023","journal-title":"Neurology"},{"key":"2024041801131473200_awad126-B117","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1089\/neu.2017.5002","article-title":"Serial assessment of grey matter abnormalities after sport-related concussion","volume":"34","author":"Espa\u00f1a","year":"2017","journal-title":"J Neurotrauma."},{"key":"2024041801131473200_awad126-B118","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1136\/bjsports-2020-102002","article-title":"Prospective study of the association between sport-related concussion and brain morphometry (3T-MRI) in collegiate athletes: Study from the NCAA-DoD CARE consortium","volume":"55","author":"Bobholz","year":"2021","journal-title":"Br J Sports Med"},{"key":"2024041801131473200_awad126-B119","volume-title":"Traumatic brain injury: A roadmap for accelerating progress","author":"National Academies of Sciences, Engineering, and Medicine","year":"2022"},{"key":"2024041801131473200_awad126-B120","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1056\/NEJMoa1706640","article-title":"Letermovir prophylaxis for cytomegalovirus in hematopoietic-cell transplantation","volume":"377","author":"Marty","year":"2017","journal-title":"N Engl J Med"},{"key":"2024041801131473200_awad126-B121","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/nrd1065","article-title":"Antiherpesvirus drugs: A promising spectrum of new drugs and drug targets","volume":"2","author":"Coen","year":"2003","journal-title":"Nat Rev Drug Discov"},{"key":"2024041801131473200_awad126-B122","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.jcv.2019.04.007","article-title":"New vaccines and antiviral drugs for cytomegalovirus","volume":"116","author":"Griffiths","year":"2019","journal-title":"J Clin Virol"},{"key":"2024041801131473200_awad126-B123","doi-asserted-by":"crossref","first-page":"551","DOI":"10.3390\/vaccines9060551","article-title":"Development of a vaccine against human cytomegalovirus: Advances, barriers, and implications for the clinical practice","volume":"9","author":"Scarpini","year":"2021","journal-title":"Vaccines (Basel)."}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/brain\/advance-article-pdf\/doi\/10.1093\/brain\/awad126\/50596227\/awad126.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/brain\/article-pdf\/146\/10\/4262\/51824019\/awad126.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/brain\/article-pdf\/146\/10\/4262\/51824019\/awad126.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T01:14:22Z","timestamp":1713402862000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article\/146\/10\/4262\/7127565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,18]]},"references-count":123,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,4,18]]},"published-print":{"date-parts":[[2023,10,3]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awad126","relation":{},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,10]]},"published":{"date-parts":[[2023,4,18]]}}}