{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T12:11:15Z","timestamp":1791115875869,"version":"4.1.0"},"reference-count":68,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,6]]},"DOI":"10.1093\/brain\/awg139","type":"journal-article","created":{"date-parts":[[2003,5,22]],"date-time":"2003-05-22T23:28:43Z","timestamp":1053646123000},"page":"1392-1408","source":"Crossref","is-referenced-by-count":44,"title":["Impairment of context\u2010adapted movement selection in a primate model of presymptomatic Parkinson\u2019s disease"],"prefix":"10.1093","volume":"126","author":[{"given":"Mathias","family":"Pessiglione","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Guehl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Agid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne C.","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"F\u00e9ger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9on","family":"Tremblay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2003,6]]},"reference":[{"key":"key\n\t\t\t\t20170624071739_AWG139C1","doi-asserted-by":"crossref","unstructured":"Aosaki T, Tsubokawa H, Ishida A, Watanabe K, Graybiel AM, Kimura M. Responses of tonically active neurons in the primate\u2019s striatum undergo systematic changes during behavioral sensorimotor conditioning. J Neurosci1994; 14: 3969\u201384.","DOI":"10.1523\/JNEUROSCI.14-06-03969.1994"},{"key":"key\n\t\t\t\t20170624071739_AWG139C2","doi-asserted-by":"crossref","unstructured":"Bard C, Turrell Y, Fleury M, Teasdale N, Lamarre Y, Martin O. Deafferentation and pointing with visual double\u2010step perturbations. Exp Brain Res1999; 125: 410\u20136.","DOI":"10.1007\/s002210050697"},{"key":"key\n\t\t\t\t20170624071739_AWG139C3","doi-asserted-by":"crossref","unstructured":"Beppu H, Nagaoka M, Tanaka R. Analysis of cerebellar motor disorders by visually\u2010guided elbow tracking movement. 2. Contribution of the visual cues on slow ramp pursuit. Brain1987; 110: 1\u201318.","DOI":"10.1093\/brain\/110.1.1"},{"key":"key\n\t\t\t\t20170624071739_AWG139C4","doi-asserted-by":"crossref","unstructured":"Berns GS, Sejnowski TJ. How the basal ganglia make decisions. In: Damasio AR, Damasio H, Christen Y, editors. Neurobiology of decision\u2010making. Berlin: Springer Verlag; 1996. p. 101\u201313.","DOI":"10.1007\/978-3-642-79928-0_6"},{"key":"key\n\t\t\t\t20170624071739_AWG139C5","doi-asserted-by":"crossref","unstructured":"Bonnefoi\u2010Kyriacou B, Legallet E, Lee RG, Trouche E. Spatio\u2010temporal and kinematic analysis of pointing movements performed by cerebellar patients with limb ataxia. Exp Brain Res1998; 119: 460\u20136.","DOI":"10.1007\/s002210050361"},{"key":"key\n\t\t\t\t20170624071739_AWG139C6","doi-asserted-by":"crossref","unstructured":"Brown JR, Arbuthnott GW. The electrophysiology of dopamine (D2) receptors: a study of the actions of dopamine on corticostriatal transmission. Neuroscience1983; 10: 349\u201355.","DOI":"10.1016\/0306-4522(83)90138-0"},{"key":"key\n\t\t\t\t20170624071739_AWG139C7","doi-asserted-by":"crossref","unstructured":"Burns RS. Subclinical damage to the nigrostriatal dopamine system by MPTP as a model of preclinical Parkinson\u2019s disease: a review. Acta Neurol Scand Suppl 1991; 136: 29\u201336.","DOI":"10.1111\/j.1600-0404.1991.tb05017.x"},{"key":"key\n\t\t\t\t20170624071739_AWG139C8","doi-asserted-by":"crossref","unstructured":"Calabresi P, Gubellini P, Centonze D, Picconi B, Bernardi, Chergui K, et al. Dopamine and cAMP\u2010regulated phosphoprotein 32 kDa controls both striatal long\u2010term depression and long\u2010term potentiation, opposing forms of synaptic plasticity. J Neurosci2000; 20: 8443\u201351.","DOI":"10.1523\/JNEUROSCI.20-22-08443.2000"},{"key":"key\n\t\t\t\t20170624071739_AWG139C9","doi-asserted-by":"crossref","unstructured":"Cooper JA, Sagar HJ, Jordan N, Harvey NS, Sullivan EV. Cognitive impairment in early, untreated Parkinson\u2019s disease and its relationship to motor disability. Brain1991; 114: 2095\u2013122.","DOI":"10.1093\/brain\/114.5.2095"},{"key":"key\n\t\t\t\t20170624071739_AWG139C10","doi-asserted-by":"crossref","unstructured":"DeLong MR. Putamen: activity of single units during slow and rapid arm movements. Science1973; 179: 1240\u20132.","DOI":"10.1126\/science.179.4079.1240"},{"key":"key\n\t\t\t\t20170624071739_AWG139C11","doi-asserted-by":"crossref","unstructured":"Desmurget M, Epstein CM, Turner RS, Prablanc C, Alexander GE, Grafton ST. Role of the posterior parietal cortex in updating reaching movements to a visual target. Nat Neurosci1999; 2: 563\u20137.","DOI":"10.1038\/9219"},{"key":"key\n\t\t\t\t20170624071739_AWG139C12","doi-asserted-by":"crossref","unstructured":"Dominey PF. Complex sensory\u2010motor sequence learning based on recurrent state representation and reinforcement learning. Biol Cybern1995; 73: 265\u201374.","DOI":"10.1007\/BF00201428"},{"key":"key\n\t\t\t\t20170624071739_AWG139C13","doi-asserted-by":"crossref","unstructured":"Doudet D, Gross C, Lebrun\u2010Grandie P, Bioulac B. MPTP primate model of Parkinson\u2019s disease: a mechanographic and electromyographic study. Brain Res1985; 335: 194\u20139.","DOI":"10.1016\/0006-8993(85)90294-X"},{"key":"key\n\t\t\t\t20170624071739_AWG139C14","doi-asserted-by":"crossref","unstructured":"Dubois B, Pillon B, Agid Y. Deterioration of dopaminergic pathways and alterations in cognition and motor functions. J Neurol1992; 239 Suppl 1: S9\u201312.","DOI":"10.1007\/BF00819560"},{"key":"key\n\t\t\t\t20170624071739_AWG139C15","doi-asserted-by":"crossref","unstructured":"Elsworth JD, Taylor JR, Sladek JR Jr, Collier TJ, Redmond DE Jr, Roth RH. Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old\u2010world primates one year after MPTP treatment. Neuroscience2000; 95: 399\u2013408.","DOI":"10.1016\/S0306-4522(99)00437-6"},{"key":"key\n\t\t\t\t20170624071739_AWG139C16","doi-asserted-by":"crossref","unstructured":"Evarts EV, Teravainen H, Calne DB. Reaction time in Parkinson\u2019s disease. Brain1981; 104: 167\u201386.","DOI":"10.1093\/brain\/104.1.167"},{"key":"key\n\t\t\t\t20170624071739_AWG139C17","doi-asserted-by":"crossref","unstructured":"Filion M, Tremblay L, Bedard PJ. Abnormal influences of passive limb movement on the activity of globus pallidus neurons in parkinsonian monkeys. Brain Res1988; 444: 165\u201376.","DOI":"10.1016\/0006-8993(88)90924-9"},{"key":"key\n\t\t\t\t20170624071739_AWG139C18","doi-asserted-by":"crossref","unstructured":"Flowers KA. Visual \u2018closed\u2010loop\u2019 and \u2018open\u2010loop\u2019 characteristics of voluntary movement in patients with Parkinsonism and intention tremor. Brain1976; 99: 269\u2013310.","DOI":"10.1093\/brain\/99.2.269"},{"key":"key\n\t\t\t\t20170624071739_AWG139C19","doi-asserted-by":"crossref","unstructured":"Francois C, Yelnik J, Tande D, Agid Y, Hirsch EC. Dopaminergic cell group A8 in the monkey: anatomical organization and projections to the striatum. J Comp Neurol1999; 414: 334\u201347.","DOI":"10.1002\/(SICI)1096-9861(19991122)414:3<334::AID-CNE4>3.0.CO;2-X"},{"key":"key\n\t\t\t\t20170624071739_AWG139C20","doi-asserted-by":"crossref","unstructured":"Garcia\u2010Munoz M, Young SJ, Groves PM. Terminal excitability of the corticostriatal pathway. I. Regulation by dopamine receptor stimulation. Brain Res1991; 551: 195\u2013206.","DOI":"10.1016\/0006-8993(91)90933-M"},{"key":"key\n\t\t\t\t20170624071739_AWG139C21","doi-asserted-by":"crossref","unstructured":"Gerfen CR, Engber TM, Mahan LC, Susel Z, Chase TN, Monsma FJ Jr, et al. D1 and D2 dopamine receptor\u2010regulated gene expression of striatonigral and striatopallidal neurons. Science1990; 250: 1429\u201332.","DOI":"10.1126\/science.2147780"},{"key":"key\n\t\t\t\t20170624071739_AWG139C101","doi-asserted-by":"crossref","unstructured":"Glickstein M, Stein J. Paradoxical movement in Parkinson\u2019s disease. Trends Neurosci1991; 14: 480\u20132.","DOI":"10.1016\/0166-2236(91)90055-Y"},{"key":"key\n\t\t\t\t20170624071739_AWG139C22","doi-asserted-by":"crossref","unstructured":"Goodale MA, Pelisson D, Prablanc C. Large adjustments in visually guided reaching do not depend on vision of the hand or perception of target displacement. Nature1986; 320: 748\u201350.","DOI":"10.1038\/320748a0"},{"key":"key\n\t\t\t\t20170624071739_AWG139C23","doi-asserted-by":"crossref","unstructured":"Graziano MS, Gross CG. A bimodal map of space: somatosensory receptive fields in the macaque putamen with corresponding visual receptive fields. Exp Brain Res1993; 97: 96\u2013109.","DOI":"10.1007\/BF00228820"},{"key":"key\n\t\t\t\t20170624071739_AWG139C24","doi-asserted-by":"crossref","unstructured":"Gurney K, Prescott TJ, Redgrave P. A computational model of action selection in the basal ganglia. I. A new functional anatomy. Biol Cybern2001; 84: 401\u201310.","DOI":"10.1007\/PL00007984"},{"key":"key\n\t\t\t\t20170624071739_AWG139C25","doi-asserted-by":"crossref","unstructured":"Hikosaka O, Sakamoto M, Usui S. Functional properties of monkey caudate neurons. I. Activities related to saccadic eye movements. J Neurophysiol1989a; 61: 780\u201398.","DOI":"10.1152\/jn.1989.61.4.780"},{"key":"key\n\t\t\t\t20170624071739_AWG139C26","doi-asserted-by":"crossref","unstructured":"Hikosaka O, Sakamoto M, Usui S. Functional properties of monkey caudate neurons. II. Visual and auditory responses. J Neurophysiol1989b; 61: 799\u2013813.","DOI":"10.1152\/jn.1989.61.4.799"},{"key":"key\n\t\t\t\t20170624071739_AWG139C27","unstructured":"Hirsch EC, Herrero MT. Neurochemical correlates of parkinsonism. Role of dopaminergic lesions. Adv Neurol1997; 74: 119\u201326."},{"key":"key\n\t\t\t\t20170624071739_AWG139C28","doi-asserted-by":"crossref","unstructured":"Houk JC, Adams JL, Barto AG. A model of how the basal ganglia generate and use neural signals that predict reinforcement. In: Houk JC, Davis JL, Beiser DG, editors. Models of information processing in the basal ganglia. Cambridge (MA): MIT Press; 1995. p. 249\u201370.","DOI":"10.7551\/mitpress\/4708.003.0020"},{"key":"key\n\t\t\t\t20170624071739_AWG139C29","doi-asserted-by":"crossref","unstructured":"Inase M, Buford JA, Anderson ME. Changes in the control of arm position, movement, and thalamic discharge during local inactivation in the globus pallidus of the monkey. J Neurophysiol1996; 75: 1087\u2013104.","DOI":"10.1152\/jn.1996.75.3.1087"},{"key":"key\n\t\t\t\t20170624071739_AWG139C30","doi-asserted-by":"crossref","unstructured":"Jackson SR, Jackson GM, Harrison J, Henderson L, Kennard C. The internal control of action and Parkinson\u2019s disease: a kinematic analysis of visually\u2010guided and memory\u2010guided prehension movements. Exp Brain Res1995; 105: 147\u201362.","DOI":"10.1007\/BF00242190"},{"key":"key\n\t\t\t\t20170624071739_AWG139C31","unstructured":"Javoy\u2010Agid F, Ruberg M, Taquet H, Bokobza B, Agid Y, Gaspar P, et al. Biochemical neuropathology of Parkinson\u2019s disease. Adv Neurol1984; 40: 189\u201398."},{"key":"key\n\t\t\t\t20170624071739_AWG139C32","doi-asserted-by":"crossref","unstructured":"Jog MS, Kubota Y, Connolly CI, Hillegaart V, Graybiel AM. Building neural representations of habits. Science1999; 286: 1745\u20139.","DOI":"10.1126\/science.286.5445.1745"},{"key":"key\n\t\t\t\t20170624071739_AWG139C33","doi-asserted-by":"crossref","unstructured":"Jueptner M, Weiller C. A review of differences between basal ganglia and cerebellar control of movements as revealed by functional imaging studies. Brain1998; 121: 1437\u201349.","DOI":"10.1093\/brain\/121.8.1437"},{"key":"key\n\t\t\t\t20170624071739_AWG139C34","doi-asserted-by":"crossref","unstructured":"Knowlton BJ, Mangels JA, Squire LR. A neostriatal habit learning system in humans. Science1996; 273: 1399\u2013402.","DOI":"10.1126\/science.273.5280.1399"},{"key":"key\n\t\t\t\t20170624071739_AWG139C102","doi-asserted-by":"crossref","unstructured":"Langston JW, Ballard P, Tretrud JW, Irwin I. Chronic parkinsonism in humans due to a product of meperidine\u2010analog synthesis. Science1983; 219: 979\u201380.","DOI":"10.1126\/science.6823561"},{"key":"key\n\t\t\t\t20170624071739_AWG139C35","doi-asserted-by":"crossref","unstructured":"Liste I, Rozas G, Guerra MJ, Labandeira\u2010Garcia JL. Cortical stimulation induces Fos expression in striatal neurons via NMDA glutamate and dopamine receptors. Brain Res1995; 700: 1\u201312.","DOI":"10.1016\/0006-8993(95)00958-S"},{"key":"key\n\t\t\t\t20170624071739_AWG139C36","doi-asserted-by":"crossref","unstructured":"McDonald RJ, White NM. A triple dissociation of memory systems: hippocampus, amygdala, and dorsal striatum. Behav Neurosci1993; 107: 3\u201322.","DOI":"10.1037\/0735-7044.107.1.3"},{"key":"key\n\t\t\t\t20170624071739_AWG139C37","doi-asserted-by":"crossref","unstructured":"Mink JW, Thach WT. Basal ganglia motor control. III. Pallidal ablation: normal reaction time, muscle cocontraction, and slow movement. J Neurophysiol1991; 65: 330\u201351.","DOI":"10.1152\/jn.1991.65.2.330"},{"key":"key\n\t\t\t\t20170624071739_AWG139C38","doi-asserted-by":"crossref","unstructured":"Mink JW, Thach WT. Basal ganglia intrinsic circuits and their role in behavior. Curr Opin Neurobiol1993; 3: 950\u20137.","DOI":"10.1016\/0959-4388(93)90167-W"},{"key":"key\n\t\t\t\t20170624071739_AWG139C39","doi-asserted-by":"crossref","unstructured":"Miyachi S, Hikosaka O, Miyashita K, Karadi Z, Rand MK. Differential roles of monkey striatum in learning of sequential hand movement. Exp Brain Res1997; 115: 1\u20135.","DOI":"10.1007\/PL00005669"},{"key":"key\n\t\t\t\t20170624071739_AWG139C40","doi-asserted-by":"crossref","unstructured":"Mushiake H, Strick PL. Preferential activity of dentate neurons during limb movements guided by vision. J Neurophysiol1993; 70: 2660\u20134.","DOI":"10.1152\/jn.1993.70.6.2660"},{"key":"key\n\t\t\t\t20170624071739_AWG139C41","doi-asserted-by":"crossref","unstructured":"Mushiake H, Strick PL. Pallidal neuron activity during sequential arm movements. J Neurophysiol1995; 74: 2754\u20138.","DOI":"10.1152\/jn.1995.74.6.2754"},{"key":"key\n\t\t\t\t20170624071739_AWG139C42","doi-asserted-by":"crossref","unstructured":"Packard MG, McGaugh JL. Inactivation of hippocampus or caudate nucleus with lidocaine differentially affects expression of place and response learning. Neurobiol Learn Mem1996; 65: 65\u201372.","DOI":"10.1006\/nlme.1996.0007"},{"key":"key\n\t\t\t\t20170624071739_AWG139C43","unstructured":"Pessiglione M, Guehl D, Hirsch EC, Agid Y, F\u00e9ger J, Tremblay L. Context\u2010adapted movement selection impairment in early stages of progressive MPTP\u2010induced parkinsonism in monkey [abstract]. Soc Neurosci Abstr2001; 27: Program No. 533.8."},{"key":"key\n\t\t\t\t20170624071739_AWG139C44","doi-asserted-by":"crossref","unstructured":"Prablanc C, Martin O. Automatic control during hand reaching at undetected two\u2010dimensional target displacements. J Neurophysiol1992; 67: 455\u201369.","DOI":"10.1152\/jn.1992.67.2.455"},{"key":"key\n\t\t\t\t20170624071739_AWG139C45","doi-asserted-by":"crossref","unstructured":"Przedborski S, Jackson\u2010Lewis V, Naini AB, Jakowec M, Petzinger G, Miller R, et al. The parkinsonian toxin 1\u2010methyl\u20104\u2010phenyl\u20101,2,3,6\u2010tetrahydropyridine (MPTP): a technical review of its utility and safety. J Neurochem2001; 76: 1265\u201374.","DOI":"10.1046\/j.1471-4159.2001.00183.x"},{"key":"key\n\t\t\t\t20170624071739_AWG139C46","doi-asserted-by":"crossref","unstructured":"Pullman SL, Watts RL, Juncos JL, Chase TN, Sanes JN. Dopaminergic effects on simple and choice reaction time performance in Parkinson\u2019s disease. Neurology1988; 38: 249\u201354.","DOI":"10.1212\/WNL.38.2.249"},{"key":"key\n\t\t\t\t20170624071739_AWG139C47","doi-asserted-by":"crossref","unstructured":"Romo R, Scarnati E, Schultz W. Role of primate basal ganglia and frontal cortex in the internal generation of movements. II. Movement\u2010related activity in the anterior striatum. Exp Brain Res1992; 91: 385\u201395.","DOI":"10.1007\/BF00227835"},{"key":"key\n\t\t\t\t20170624071739_AWG139C48","doi-asserted-by":"crossref","unstructured":"Saint\u2010Cyr JA, Taylor AE, Lang AE. Procedural learning and neostriatal dysfunction in man. Brain1988; 111: 941\u201359.","DOI":"10.1093\/brain\/111.4.941"},{"key":"key\n\t\t\t\t20170624071739_AWG139C49","doi-asserted-by":"crossref","unstructured":"Schneider JS. Chronic exposure to low doses of MPTP. II. Neurochemical and pathological consequences in cognitively\u2010impaired, motor asymptomatic monkeys. Brain Res1990; 534: 25\u201336.","DOI":"10.1016\/0006-8993(90)90108-N"},{"key":"key\n\t\t\t\t20170624071739_AWG139C50","doi-asserted-by":"crossref","unstructured":"Schneider JS, Kovelowski CJ. Chronic exposure to low doses of MPTP. I. Cognitive deficits in motor asymptomatic monkeys. Brain Res1990; 519: 122\u20138.","DOI":"10.1016\/0006-8993(90)90069-N"},{"key":"key\n\t\t\t\t20170624071739_AWG139C51","doi-asserted-by":"crossref","unstructured":"Schultz W. Responses of midbrain dopamine neurons to behavioral trigger stimuli in the monkey. J Neurophysiol1986; 56: 1439\u201361.","DOI":"10.1152\/jn.1986.56.5.1439"},{"key":"key\n\t\t\t\t20170624071739_AWG139C52","doi-asserted-by":"crossref","unstructured":"Schultz W, Romo R. Role of primate basal ganglia and frontal cortex in the internal generation of movements. I. Preparatory activity in the anterior striatum. Exp Brain Res1992; 91: 363\u201384.","DOI":"10.1007\/BF00227834"},{"key":"key\n\t\t\t\t20170624071739_AWG139C53","doi-asserted-by":"crossref","unstructured":"Schultz W, Studer A, Romo R, Sundstrom E, Jonsson G, Scarnati E. Deficits in reaction times and movement times as correlates of hypokinesia in monkeys with MPTP\u2010induced striatal dopamine depletion. J Neurophysiol1989; 61: 651\u201368.","DOI":"10.1152\/jn.1989.61.3.651"},{"key":"key\n\t\t\t\t20170624071739_AWG139C54","doi-asserted-by":"crossref","unstructured":"Schultz W, Apicella P, Ljungberg T. Responses of monkey dopamine neurons to reward and conditioned stimuli during successive steps of learning a delayed response task. J Neurosci1993; 13: 900\u201313.","DOI":"10.1523\/JNEUROSCI.13-03-00900.1993"},{"key":"key\n\t\t\t\t20170624071739_AWG139C55","doi-asserted-by":"crossref","unstructured":"Schultz W, Dayan P, Montague PR. A neural substrate of prediction and reward. Science1997; 275: 1593\u20139.","DOI":"10.1126\/science.275.5306.1593"},{"key":"key\n\t\t\t\t20170624071739_AWG139C56","doi-asserted-by":"crossref","unstructured":"Slovin H, Abeles M, Vaadia E, Haalman I, Prut Y, Bergman H. Frontal cognitive impairments and saccadic deficits in low\u2010dose MPTP\u2010treated monkeys. J Neurophysiol1999; 81: 858\u201374.","DOI":"10.1152\/jn.1999.81.2.858"},{"key":"key\n\t\t\t\t20170624071739_AWG139C57","doi-asserted-by":"crossref","unstructured":"Smith AD, Bolam JP. The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones. Trends Neurosci1990; 13: 259\u201365.","DOI":"10.1016\/0166-2236(90)90106-K"},{"key":"key\n\t\t\t\t20170624071739_AWG139C58","doi-asserted-by":"crossref","unstructured":"Soechting JF, Lacquaniti F. Modification of trajectory of a pointing movement in response to a change in target location. J Neurophysiol1983; 49: 548\u201364.","DOI":"10.1152\/jn.1983.49.2.548"},{"key":"key\n\t\t\t\t20170624071739_AWG139C59","doi-asserted-by":"crossref","unstructured":"Stern Y, Tetrud JW, Martin WR, Kutner SJ, Langston JW. Cognitive change following MPTP exposure. Neurology1990; 40: 261\u20134.","DOI":"10.1212\/WNL.40.2.261"},{"key":"key\n\t\t\t\t20170624071739_AWG139C60","doi-asserted-by":"crossref","unstructured":"Taylor JR, Elsworth JD, Roth RH, Sladek JR Jr, Redmond DE Jr. Cognitive and motor deficits in the acquisition of an object retrieval\/detour task in MPTP\u2010treated monkeys. Brain1990; 113: 617\u201337.","DOI":"10.1093\/brain\/113.3.617"},{"key":"key\n\t\t\t\t20170624071739_AWG139C61","doi-asserted-by":"crossref","unstructured":"Taylor JR, Elsworth JD, Roth RH, Sladek JR Jr, Redmond DE Jr. Severe long\u2010term 1\u2010methyl\u20104\u2010phenyl\u20101,2,3,6\u2010tetrahydropyridine\u2010induced parkinsonism in the vervet monkey (Cercopithecus aethiops sabaeus). Neuroscience1997; 81: 745\u201355.","DOI":"10.1016\/S0306-4522(97)00214-5"},{"key":"key\n\t\t\t\t20170624071739_AWG139C62","doi-asserted-by":"crossref","unstructured":"Toan DL, Schultz W. Responses of rat pallidum cells to cortex stimulation and effects of altered dopaminergic activity. Neuroscience1985; 15: 683\u201394.","DOI":"10.1016\/0306-4522(85)90070-3"},{"key":"key\n\t\t\t\t20170624071739_AWG139C63","doi-asserted-by":"crossref","unstructured":"Tremblay L, Filion M, Bedard PJ. Responses of pallidal neurons to striatal stimulation in monkeys with MPTP\u2010induced parkinsonism. Brain Res1989; 498: 17\u201333.","DOI":"10.1016\/0006-8993(89)90395-8"},{"key":"key\n\t\t\t\t20170624071739_AWG139C64","doi-asserted-by":"crossref","unstructured":"Tremblay L, Hollerman JR, Schultz W. Modifications of reward expectation\u2010related neuronal activity during learning in primate striatum. J Neurophysiol1998; 80: 964\u201377.","DOI":"10.1152\/jn.1998.80.2.964"},{"key":"key\n\t\t\t\t20170624071739_AWG139C65","doi-asserted-by":"crossref","unstructured":"van Donkelaar P, Lee RG. Interactions between the eye and hand motor systems: disruptions due to cerebellar dysfunction. J Neurophysiol1994; 72: 1674\u201385.","DOI":"10.1152\/jn.1994.72.4.1674"},{"key":"key\n\t\t\t\t20170624071739_AWG139C66","doi-asserted-by":"crossref","unstructured":"Wickens JR, Begg AJ, Arbuthnott GW. Dopamine reverses the depression of rat corticostriatal synapses which normally follows high\u2010frequency stimulation of cortex in vitro. Neuroscience1996; 70: 1\u20135.","DOI":"10.1016\/0306-4522(95)00436-M"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/126\/6\/1392\/9172076\/awg139.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,9]],"date-time":"2024-01-09T22:03:56Z","timestamp":1704837836000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/awg139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6]]},"references-count":68,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2003,6]]},"published-print":{"date-parts":[[2003,6]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awg139","relation":{},"ISSN":["1460-2156","0006-8950"],"issn-type":[{"value":"1460-2156","type":"electronic"},{"value":"0006-8950","type":"print"}],"subject":[],"published":{"date-parts":[[2003,6]]}}}