{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:27:33Z","timestamp":1791224853387,"version":"4.1.0"},"reference-count":61,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1093\/brain\/awn012","type":"journal-article","created":{"date-parts":[[2008,2,2]],"date-time":"2008-02-02T20:24:51Z","timestamp":1201983891000},"page":"732-746","source":"Crossref","is-referenced-by-count":308,"title":["Phenotype variability in progranulin mutation carriers: a clinical, neuropsychological, imaging and genetic study"],"prefix":"10.1093","volume":"131","author":[{"given":"Isabelle","family":"Le Ber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agn\u00e8s","family":"Camuzat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Hannequin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Pasquier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Guedj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Rovelet-Lecrux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Hahn-Barma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"van der Zee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabienne","family":"Clot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serge","family":"Bakchine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mich\u00e8le","family":"Puel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustapha","family":"Ghanim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucette","family":"Lacomblez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Mikol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Deramecourt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Lejeune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"de la Sayette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serge","family":"Belliard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Vercelletto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Meyrignac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Van Broeckhoven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Charles","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice","family":"Verpillat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Campion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Odile","family":"Habert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Dubois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis","family":"Brice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,2,2]]},"reference":[{"key":"key\n\t\t\t\t20170424184830_B1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1742-2094-4-7","article-title":"Progranulin in frontotemporal lobar degeneration and neuroinflammation","volume":"4","author":"Ahmed","year":"2007","journal-title":"J Neuroinflammation"},{"key":"key\n\t\t\t\t20170424184830_B2","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1038\/nature05016","article-title":"Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17","volume":"442","author":"Baker","year":"2006","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170424184830_B3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/WAD.0b013e31803083f2","article-title":"Neuropathologic heterogeneity in HDDD1: a familial frontotemporal lobar degeneration with ubiquitin-positive inclusions and progranulin mutation","volume":"21","author":"Behrens","year":"2007","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"key\n\t\t\t\t20170424184830_B4","article-title":"A novel deletion in progranulin gene is associated with FTDP-17 and CBS","author":"Benussi","year":"2006","journal-title":"Neurobiol Aging"},{"key":"key\n\t\t\t\t20170424184830_B5","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1002\/ana.10570","article-title":"Corticobasal degeneration and its relationship to progressive supranuclear palsy and frontotemporal dementia","volume":"54","author":"Boeve","year":"2003","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170424184830_B6","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1093\/brain\/awl268","article-title":"Frontotemporal dementia and parkinsonism associated with the IVS1+1G \u2192 A mutation in progranulin: a clinicopathologic study","volume":"129","author":"Boeve","year":"2006","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170424184830_B7","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/sj.ejhg.5201772","article-title":"Progranulin mutations in Dutch familial frontotemporal lobar degeneration","volume":"15","author":"Bronner","year":"2007","journal-title":"Eur J Hum Genet"},{"key":"key\n\t\t\t\t20170424184830_B8","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1212\/01.wnl.0000265220.64396.b4","article-title":"Heterogeneity within a large kindred with frontotemporal dementia: a novel progranulin mutation","volume":"69","author":"Bruni","year":"2007","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B9","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/s00401-007-0237-2","article-title":"Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration","volume":"114","author":"Cairns","year":"2007","journal-title":"Acta Neuropathol (Berl)"},{"key":"key\n\t\t\t\t20170424184830_B10","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1038\/nature05017","article-title":"Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21","volume":"442","author":"Cruts","year":"2006","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170424184830_B11","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1212\/WNL.44.12.2308","article-title":"The neuropsychiatric inventory: comprehensive assessment of psychopathology in dementia","volume":"44","author":"Cummings","year":"1994","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B12","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1177\/002215540004800713","article-title":"Cellular localization of gene expression for progranulin","volume":"48","author":"Daniel","year":"2000","journal-title":"J Histochem Cytochem"},{"key":"key\n\t\t\t\t20170424184830_B13","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1212\/01.wnl.0000267701.58488.69","article-title":"Clinicopathologic correlation in PGRN mutations","volume":"69","author":"Davion","year":"2007","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B14","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1006\/brln.1996.0039","article-title":"Picture confrontation oral naming: performance differences between aphasics and normals","volume":"53","author":"Deloche","year":"1996","journal-title":"Brain Lang"},{"key":"key\n\t\t\t\t20170424184830_B15","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1212\/WNL.55.11.1621","article-title":"The FAB: a frontal assessment battery at bedside","volume":"55","author":"Dubois","year":"2000","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B16","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/S1474-4422(04)00710-0","article-title":"Amnestic MCI or prodromal Alzheimer's disease?","volume":"3","author":"Dubois","year":"2004","journal-title":"Lancet Neurol"},{"key":"key\n\t\t\t\t20170424184830_B17","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini Mental State: a practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res"},{"key":"key\n\t\t\t\t20170424184830_B18","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1093\/brain\/awm177","article-title":"FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease","volume":"130","author":"Foster","year":"2007","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170424184830_B19","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.1093\/hmg\/ddl241","article-title":"Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration","volume":"15","author":"Gass","year":"2006","journal-title":"Hum Mol Genet"},{"key":"key\n\t\t\t\t20170424184830_B20","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1212\/01.wnl.0000266638.53185.e7","article-title":"Brain spect perfusion of frontotemporal dementia associated with motor neuron disease","volume":"69","author":"Guedj","year":"2007","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B21","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1097\/00001756-199907130-00022","article-title":"Cerebral glucose metabolism in unilateral entorhinal cortex-lesioned rats: an animal PET study","volume":"10","author":"Hayashi","year":"1999","journal-title":"Neuroreport"},{"key":"key\n\t\t\t\t20170424184830_B22","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/ana.20969","article-title":"Characteristics of frontotemporal dementia patients with a Progranulin mutation","volume":"60","author":"Huey","year":"2006","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170424184830_B23","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/31508","article-title":"Association of missense and 5\u2032-splice site mutations in tau with the inherited dementia FTDP-17","volume":"393","author":"Hutton","year":"1998","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170424184830_B24","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1212\/01.wnl.0000191307.69661.c3","article-title":"Clinicopathological analysis of frontotemporal and corticobasal degenerations and PSP","volume":"66","author":"Josephs","year":"2006","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B25","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1097\/nen.0b013e31803020cf","article-title":"Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions with progranulin gene (PGRN) mutations","volume":"66","author":"Josephs","year":"2007","journal-title":"J Neuropathol Exp Neurol"},{"key":"key\n\t\t\t\t20170424184830_B26","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1159\/000051212","article-title":"Clinical and pathological overlap between frontotemporal dementia, primary progressive aphasia and corticobasal degeneration: the Pick complex","volume":"10","author":"Kertesz","year":"1999","journal-title":"Dement Geriatr Cogn Disord"},{"key":"key\n\t\t\t\t20170424184830_B27","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1017\/S1355617700644041","article-title":"The frontal behavioral inventory in the differential diagnosis of frontotemporal dementia","volume":"6","author":"Kertesz","year":"2000","journal-title":"J Int Neuropsychol Soc"},{"key":"key\n\t\t\t\t20170424184830_B28","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1093\/brain\/awh598","article-title":"The evolution and pathology of frontotemporal dementia","volume":"128","author":"Kertesz","year":"2005","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170424184830_B29","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/ana.20700","article-title":"Clinical and pathological characterization of progressive aphasia","volume":"59","author":"Knibb","year":"2006","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170424184830_B30","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/00002093-199812000-00014","article-title":"Frontotemporal behavioural scale","volume":"12","author":"Lebert","year":"1998","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"key\n\t\t\t\t20170424184830_B31","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.1093\/brain\/awl288","article-title":"Demographic, neurological and behavioural characteristics and brain perfusion SPECT in frontal variant of frontotemporal dementia","volume":"129","author":"Le Ber","year":"2006","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170424184830_B32","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1002\/humu.20520","article-title":"Progranulin null mutations in both sporadic and familial frontotemporal dementia","volume":"28","author":"Le Ber","year":"2007","journal-title":"Hum Mutat"},{"key":"key\n\t\t\t\t20170424184830_B33","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1093\/brain\/awm069","article-title":"Novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology","volume":"130","author":"Leverenz","year":"2007","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170424184830_B34","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s00401-007-0223-8","article-title":"The neuropathology and clinical phenotype of FTD with progranulin mutations","volume":"114","author":"Mackenzie","year":"2007","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170424184830_B35","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1093\/brain\/awl276","article-title":"Novel splicing mutation in the progranulin gene causing familial corticobasal syndrome","volume":"129","author":"Masellis","year":"2006","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170424184830_B36","volume-title":"Dementia Rating Scale.","author":"Mattis","year":"1988"},{"key":"key\n\t\t\t\t20170424184830_B37","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1093\/brain\/122.8.1519","article-title":"Neocortical and hippocampal glucose hypometabolism following neurotoxic lesions of the entorhinal and perirhinal cortices in the non-human primate as shown by PET. Implications for Alzheimer's disease","volume":"122","author":"Meguro","year":"1999","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170424184830_B38","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1212\/01.WNL.0000090563.97453.90","article-title":"Speech and language in progressive nonfluent aphasia compared with early Alzheimer's disease","volume":"61","author":"Mendez","year":"2003","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B39","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1002\/ana.91","article-title":"Primary progressive aphasia","volume":"49","author":"Mesulam","year":"2001","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170424184830_B40","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1001\/archneur.64.1.43","article-title":"Progranulin mutations in primary progressive aphasia: the PPA1 and PPA3 families","volume":"64","author":"Mesulam","year":"2007","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170424184830_B41","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1097\/01.WCB.0000037997.34930.67","article-title":"Brain glucose hypometabolism after perirhinal lesions in baboons: implications for Alzheimer disease and aging","volume":"22","author":"Millien","year":"2002","journal-title":"J Cereb Blood Flow Metab"},{"key":"key\n\t\t\t\t20170424184830_B42","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1002\/ana.20963","article-title":"HDDD2 is a familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions caused by a missense mutation in the signal peptide of progranulin","volume":"60","author":"Mukherjee","year":"2006","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170424184830_B43","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1212\/WNL.51.6.1546","article-title":"Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria","volume":"51","author":"Neary","year":"1998","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B44","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1126\/science.1134108","article-title":"Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis","volume":"314","author":"Neumann","year":"2006","journal-title":"Science"},{"key":"key\n\t\t\t\t20170424184830_B45","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1212\/WNL.44.7.1264","article-title":"Are explicit memory disorders of progressive supranuclear palsy related to damage to striatofrontal circuits? Comparison with Alzheimer's, Parkinson's, and Huntington's diseases","volume":"44","author":"Pillon","year":"1994","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B46","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1002\/ana.410430617","article-title":"Tau is a candidate gene for chromosome 17 frontotemporal dementia","volume":"43","author":"Poorkaj","year":"1998","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170424184830_B47","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S1474-4422(07)70221-1","article-title":"Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C \u2192 T (Arg493X) mutation: an international initiative","volume":"6","author":"Rademakers","year":"2007","journal-title":"Lancet Neurol"},{"key":"key\n\t\t\t\t20170424184830_B48","volume-title":"Test de copie et de reproduction de m\u00e9moire de figures g\u00e9om\u00e9triques complexes.","author":"Rey","year":"1959"},{"key":"key\n\t\t\t\t20170424184830_B49","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/ng1718","article-title":"APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy","volume":"38","author":"Rovelet-Lecrux","year":"2006","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170424184830_B50","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1136\/jnnp.2006.109553","article-title":"Progranulin mutations and ALS or ALS-FTD phenotypes","volume":"78","author":"Schymick","year":"2007","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key\n\t\t\t\t20170424184830_B51","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1093\/brain\/awl267","article-title":"Progranulin gene mutations associated with frontotemporal dementia and progressive non-fluent aphasia","volume":"129","author":"Snowden","year":"2006","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170424184830_B52","doi-asserted-by":"crossref","first-page":"7737","DOI":"10.1073\/pnas.95.13.7737","article-title":"Mutation in the tau gene in familial multiple system tauopathy with presenile dementia","volume":"95","author":"Spillantini","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170424184830_B53","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1097\/nen.0b013e3181567873","article-title":"Corticobasal syndrome associated with the A9D Progranulin mutation","volume":"66","author":"Spina","year":"2007","journal-title":"J Neuropathol Exp Neurol"},{"key":"key\n\t\t\t\t20170424184830_B54","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1212\/01.wnl.0000254460.31273.2d","article-title":"Clinicopathologic features of frontotemporal dementia with progranulin sequence variation","volume":"68","author":"Spina","year":"2007","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B55","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1212\/01.WNL.0000140289.18472.15","article-title":"Clinical, genetic and neuropathologic characteristics of posterior cortical atrophy","volume":"63","author":"Tang-Wai","year":"2004","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170424184830_B56","first-page":"416","article-title":"Consensus statement: clinical and neuropathological criteria for fronto-temporal dementia","volume":"4","author":"The Lund and Manchester groups.","year":"1994","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key\n\t\t\t\t20170424184830_B57","first-page":"125","article-title":"Donn\u00e9es neuropsychologiques chez le sujet \u00e2g\u00e9 normal","volume-title":"D\u00e9mences et syndromes d\u00e9mentiels. Approche neuropsychologique.","author":"Thuillard","year":"1991"},{"key":"key\n\t\t\t\t20170424184830_B58","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1001\/archneur.64.8.1148","article-title":"Clinical, genetic, and pathologic characteristics of patients with frontotemporal dementia and progranulin mutations","volume":"64","author":"Van Deerlin","year":"2007","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170424184830_B59","first-page":"25","article-title":"L\u2019\u00e9preuve de rappel libre\/rappel indic\u00e9 de 16 items (RL\/RI-16)","volume-title":"L\u2019\u00e9valuation des troubles de la m\u00e9moire.","author":"Van der Linden","year":"2004"},{"key":"key\n\t\t\t\t20170424184830_B60","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1002\/humu.9484","article-title":"Mutations other than null mutations producing a pathogenic loss of progranulin in frontotemporal dementia","volume":"28","author":"van der Zee","year":"2007","journal-title":"Hum Mutat"},{"key":"key\n\t\t\t\t20170424184830_B61","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1001\/archneur.64.3.371","article-title":"Voxel-based morphometry in frontotemporal lobar degeneration with ubiquitin-positive inclusions with and without progranulin mutations","volume":"64","author":"Whitwell","year":"2007","journal-title":"Arch Neurol"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/131\/3\/732\/13735826\/awn012.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T20:05:56Z","timestamp":1503432356000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/awn012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2,2]]},"references-count":61,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2008,2,2]]},"published-print":{"date-parts":[[2008,3]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awn012","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1105117.561297","asserted-by":"object"}]},"ISSN":["1460-2156","0006-8950"],"issn-type":[{"value":"1460-2156","type":"electronic"},{"value":"0006-8950","type":"print"}],"subject":[],"published":{"date-parts":[[2008,2,2]]}}}