{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:55:02Z","timestamp":1791190502661,"version":"4.1.0"},"reference-count":57,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1093\/brain\/awn281","type":"journal-article","created":{"date-parts":[[2008,10,25]],"date-time":"2008-10-25T20:24:39Z","timestamp":1224966279000},"page":"260-273","source":"Crossref","is-referenced-by-count":119,"title":["Disruption of neurofascin and gliomedin at nodes of Ranvier precedes demyelination in experimental allergic neuritis"],"prefix":"10.1093","volume":"132","author":[{"given":"Aur\u00e9lie","family":"Lonigro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me J.","family":"Devaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2008,10,25]]},"reference":[{"key":"key\n\t\t\t\t20170508032026_B1","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1002\/mus.880080609","article-title":"Sequential electrodiagnostic abnormalities in acute inflammatory demyelinating polyradiculoneuropathy","volume":"8","author":"Albers","year":"1985","journal-title":"Muscle Nerve"},{"key":"key\n\t\t\t\t20170508032026_B2","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/j.1085-9489.2005.0010207.x","article-title":"Antibodies to peripheral nerve myelin proteins in chronic inflammatory demyelinating polyradiculoneuropathy","volume":"10","author":"Allen","year":"2005","journal-title":"J Peripher Nerv Syst"},{"key":"key\n\t\t\t\t20170508032026_B3","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/cne.20321","article-title":"Acute demyelination disrupts the molecular organization of peripheral nervous system nodes","volume":"479","author":"Arroyo","year":"2004","journal-title":"J Comp Neurol"},{"key":"key\n\t\t\t\t20170508032026_B4","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0896-6273(01)00294-X","article-title":"Axon-glia interactions and the domain organization of myelinated axons requires Neurexin IV\/Caspr\/Paranodin","volume":"30","author":"Bhat","year":"2001","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170508032026_B5","doi-asserted-by":"crossref","first-page":"28996","DOI":"10.1074\/jbc.M201760200","article-title":"Interaction of the Nav1.2a subunit of the voltage-dependent sodium channel with nodal Ankyrin(G) - in vitro mapping of the interacting domains and association in synaptosomes","volume":"277","author":"Bouzidi","year":"2002","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170508032026_B6","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0896-6273(01)00296-3","article-title":"Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve","volume":"30","author":"Boyle","year":"2001","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170508032026_B7","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/S0960-9822(01)00680-7","article-title":"Neurofascin is a glial receptor for the paranodin\/Caspr-contactin axonal complex at the axoglial junction","volume":"12","author":"Charles","year":"2002","journal-title":"Curr Biol"},{"key":"key\n\t\t\t\t20170508032026_B8","doi-asserted-by":"crossref","first-page":"9529","DOI":"10.1523\/JNEUROSCI.21-24-09529.2001","article-title":"M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain","volume":"21","author":"Cooper","year":"2001","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170508032026_B9","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1083\/jcb.135.5.1355","article-title":"Molecular composition of the node of Ranvier: identification of ankyrin-binding cell adhesion molecules neurofascin (mucin + third FNIII domain-) and NrCAM at nodal axon segments","volume":"135","author":"Davis","year":"1996","journal-title":"J Cell Biol"},{"key":"key\n\t\t\t\t20170508032026_B10","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1523\/JNEUROSCI.4512-03.2004","article-title":"KCNQ2 is a nodal K + channel","volume":"24","author":"Devaux","year":"2004","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170508032026_B11","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1523\/JNEUROSCI.3328-04.2005","article-title":"Altered ion channels in an animal model of Charcot-Marie-Tooth disease type IA","volume":"25","author":"Devaux","year":"2005","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170508032026_B12","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1083\/jcb.147.6.1145","article-title":"Axo-glial interactions regulate the localization of axonal paranodal proteins","volume":"147","author":"Dupree","year":"1999","journal-title":"J Cell Biol"},{"key":"key\n\t\t\t\t20170508032026_B13","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1083\/jcb.139.6.1495","article-title":"The axonal membrane protein Caspr\/Neurexin IV is a component of the septate-like paranodal junctions that assemble during myelination","volume":"139","author":"Einheber","year":"1997","journal-title":"J Cell Biol"},{"key":"key\n\t\t\t\t20170508032026_B14","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1083\/jcb.200612139","article-title":"Secreted gliomedin is a perinodal matrix component of peripheral nerves","volume":"177","author":"Eshed","year":"2007","journal-title":"J Cell Biol"},{"key":"key\n\t\t\t\t20170508032026_B15","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.neuron.2005.06.026","article-title":"Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier","volume":"47","author":"Eshed","year":"2005","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170508032026_B16","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0165-5728(00)00270-8","article-title":"Flow cytometric analysis of infiltrating cells in the peripheral nerves in experimental allergic neuritis","volume":"108","author":"Fujioka","year":"2000","journal-title":"J Neuroimmunol"},{"key":"key\n\t\t\t\t20170508032026_B17","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0165-5728(99)00269-6","article-title":"Anti-PMP22 antibodies in patients with inflammatory neuropathy","volume":"104","author":"Gabriel","year":"2000","journal-title":"J Neuroimmunol"},{"issue":"Pt 9","key":"key\n\t\t\t\t20170508032026_B18","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1093\/brain\/120.9.1533","article-title":"Human immunoglobulin ameliorates rat experimental autoimmune neuritis","volume":"120","author":"Gabriel","year":"1997","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170508032026_B19","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/ana.410400414","article-title":"Acute motor axonal neuropathy: an antibody-mediated attack on axolemma","volume":"40","author":"Hafer-Macko","year":"1996","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170508032026_B20","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1002\/ana.410390512","article-title":"Immune attack on the Schwann cell surface in acute inflammatory demyelinating polyneuropathy","volume":"39","author":"Hafer-Macko","year":"1996","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170508032026_B21","first-page":"115","article-title":"Demyelination and axonal degeneration in Lewis rat experimental allergic neuritis depend on the myelin dosage","volume":"59","author":"Hahn","year":"1988","journal-title":"Lab Invest"},{"key":"key\n\t\t\t\t20170508032026_B22","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1007\/BF00310924","article-title":"P2-peptide induced experimental allergic neuritis - a model to study axonal degeneration","volume":"82","author":"Hahn","year":"1991","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170508032026_B23","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1212\/01.WNL.0000153071.71335.E9","article-title":"Patterns and serial changes in electrodiagnostic abnormalities of axonal Guillain-Barre syndrome","volume":"64","author":"Hiraga","year":"2005","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170508032026_B24","doi-asserted-by":"crossref","first-page":"3173","DOI":"10.1093\/brain\/awl290","article-title":"Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis","volume":"129","author":"Howell","year":"2006","journal-title":"Brain"},{"issue":"Pt 3","key":"key\n\t\t\t\t20170508032026_B25","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1093\/brain\/121.3.481","article-title":"Matrix metalloproteinase expression during experimental autoimmune neuritis","volume":"121","author":"Hughes","year":"1998","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170508032026_B26","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1002\/mus.880150506","article-title":"Sural nerve biopsies in Guillain-Barre syndrome: axonal degeneration and macrophage-associated demyelination and absence of cytomegalovirus genome","volume":"15","author":"Hughes","year":"1992","journal-title":"Muscle Nerve"},{"key":"key\n\t\t\t\t20170508032026_B27","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0165-5728(99)00195-2","article-title":"Pathogenesis of Guillain-Barre syndrome","volume":"100","author":"Hughes","year":"1999","journal-title":"J Neuroimmunol"},{"key":"key\n\t\t\t\t20170508032026_B28","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1073\/pnas.042601799","article-title":"Developing nodes of Ranvier are defined by ankyrin-G clustering and are independent of paranodal axoglial adhesion","volume":"99","author":"Jenkins","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170508032026_B29","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/277140a0","article-title":"Identification of the neuritogen for experimental allergic neuritis","volume":"277","author":"Kadlubowski","year":"1979","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170508032026_B30","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/ana.10275","article-title":"Differences in membrane properties of axonal and demyelinating Guillain-Barre syndromes","volume":"52","author":"Kuwabara","year":"2002","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170508032026_B31","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0165-5728(01)00307-1","article-title":"Investigation of serum response to PMP22, connexin 32 and P-0 in inflammatory neuropathies","volume":"116","author":"Kwa","year":"2001","journal-title":"J Neuroimmunol"},{"key":"key\n\t\t\t\t20170508032026_B32","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170508032026_B33","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1084\/jem.20071053","article-title":"Neurofascin as a novel target for autoantibody-mediated axonal injury","volume":"204","author":"Mathey","year":"2007","journal-title":"J Exp Med"},{"key":"key\n\t\t\t\t20170508032026_B34","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0896-6273(00)80942-3","article-title":"Paranodin, a glycoprotein of neuronal paranodal membranes","volume":"19","author":"Menegoz","year":"1997","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170508032026_B35","doi-asserted-by":"crossref","first-page":"3761","DOI":"10.1523\/JNEUROSCI.15-05-03761.1995","article-title":"Differential distribution of closely related potassium channels in rat Schwann cells","volume":"15","author":"Mi","year":"1995","journal-title":"J. Neurosci."},{"key":"key\n\t\t\t\t20170508032026_B36","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/j.1471-4159.1973.tb07519.x","article-title":"Myelination in rat brain. Method of myelin isolation","volume":"21","author":"Norton","year":"1973","journal-title":"J Neurochem"},{"key":"key\n\t\t\t\t20170508032026_B37","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1002\/(SICI)1097-4598(199808)21:8<1019::AID-MUS6>3.0.CO;2-B","article-title":"Disruption and reorganization of sodium channels in experimental allergic neuritis","volume":"21","author":"Novakovic","year":"1998","journal-title":"Muscle Nerve"},{"key":"key\n\t\t\t\t20170508032026_B38","doi-asserted-by":"crossref","first-page":"9418","DOI":"10.1523\/JNEUROSCI.2068-05.2005","article-title":"Both laminin and Schwann cell dystroglycan are necessary for proper clustering of sodium channels at nodes of Ranvier","volume":"25","author":"Occhi","year":"2005","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170508032026_B39","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1093\/brain\/awg254","article-title":"Calpain inhibitors protect against axonal degeneration in a model of anti-ganglioside antibody-mediated motor nerve terminal injury","volume":"126","author":"OHanlon","year":"2003","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170508032026_B40","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0165-5728(90)90068-X","article-title":"New minimum length requirement for a T cell epitope for experimental allergic neuritis","volume":"27","author":"Olee","year":"1990","journal-title":"J Neuroimmunol"},{"key":"key\n\t\t\t\t20170508032026_B41","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1523\/JNEUROSCI.4314-05.2006","article-title":"A common ankyrin-G-based mechanism retains KCNQ and Na-V channels at electrically active domains of the axon","volume":"26","author":"Pan","year":"2006","journal-title":"J Neurosci"},{"issue":"Pt 5","key":"key\n\t\t\t\t20170508032026_B42","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1093\/brain\/122.5.807","article-title":"Anti-ganglioside antibodies can bind peripheral nerve nodes of Ranvier and activate the complement cascade without inducing acute conduction block in vitro","volume":"122","author":"Paparounas","year":"1999","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170508032026_B43","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0022-510X(99)00328-7","article-title":"Immunohistochemical localization of cytokines, C5b-9 and ICAM-1 in peripheral nerve of Guillain-Barre Syndrome","volume":"174","author":"Putzu","year":"2000","journal-title":"J Neurol Sci"},{"key":"key\n\t\t\t\t20170508032026_B44","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1046\/j.1471-4159.1998.70051839.x","article-title":"Palmitoylation of neurofascin at a site in the membrane-spanning domain highly conserved among the L1 family of cell adhesion molecules","volume":"70","author":"Ren","year":"1998","journal-title":"J Neurochem"},{"key":"key\n\t\t\t\t20170508032026_B45","doi-asserted-by":"crossref","first-page":"8354","DOI":"10.1523\/JNEUROSCI.20-22-08354.2000","article-title":"Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination","volume":"20","author":"Rios","year":"2000","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170508032026_B46","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1038\/nbt859","article-title":"Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis","volume":"21","author":"Robinson","year":"2003","journal-title":"Nat Biotechnol"},{"key":"key\n\t\t\t\t20170508032026_B47","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1002\/(SICI)1097-4598(199604)19:4<474::AID-MUS8>3.0.CO;2-9","article-title":"Inflammatory infiltrates in sural nerve biopsies in Guillain-Barre syndrome and chronic inflammatory demyelinating neuropathy","volume":"19","author":"Schmidt","year":"1996","journal-title":"Muscle Nerve"},{"key":"key\n\t\t\t\t20170508032026_B48","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.neuron.2005.10.019","article-title":"Neurofascins are required to establish axonal domains for saltatory conduction","volume":"48","author":"Sherman","year":"2005","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170508032026_B49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00403-007-0734-0","article-title":"The relevance of the IgG subclass of autoantibodies for blister induction in autoimmune bullous skin diseases","volume":"299","author":"Sitaru","year":"2007","journal-title":"Arch Dermatol Res"},{"key":"key\n\t\t\t\t20170508032026_B50","doi-asserted-by":"crossref","first-page":"11215","DOI":"10.1523\/JNEUROSCI.3479-04.2004","article-title":"CNS myelin paranodes require Nkx6-2 homeoprotein transcriptional activity for normal structure","volume":"24","author":"Southwood","year":"2004","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170508032026_B51","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/ana.410300205","article-title":"Presence of the terminal complement complex (C5b-9) precedes myelin degradation in immune-mediated demyelination of the rat peripheral nervous system","volume":"30","author":"Stoll","year":"1991","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170508032026_B52","doi-asserted-by":"crossref","first-page":"3956","DOI":"10.1523\/JNEUROSCI.4401-06.2007","article-title":"Anti-GM1 antibodies cause complement-mediated disruption of sodium channel clusters in peripheral motor nerve fibers","volume":"27","author":"Susuki","year":"2007","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170508032026_B53","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1083\/jcb.150.3.657","article-title":"An oligodendrocyte cell adhesion molecule at the site of assembly of the paranodal axo-glial junction","volume":"150","author":"Tait","year":"2000","journal-title":"J Cell Biol"},{"key":"key\n\t\t\t\t20170508032026_B54","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1111\/j.1471-4159.1982.tb07979.x","article-title":"Neuritogenic determinant of bovine P2 protein in peripheral nerve myelin","volume":"39","author":"Uyemura","year":"1982","journal-title":"J Neurochem"},{"key":"key\n\t\t\t\t20170508032026_B55","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1097\/01.wco.0000245367.36576.e9","article-title":"Bacterial infections in Guillain-Barre and Fisher syndromes","volume":"19","author":"Yuki","year":"2006","journal-title":"Curr Opin Neurol"},{"key":"key\n\t\t\t\t20170508032026_B56","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/0022-510X(94)90025-6","article-title":"The B cell repertoire in experimental allergic neuritis involves multiple myelin proteins and GM1","volume":"125","author":"Zhu","year":"1994","journal-title":"J Neurol Sci"},{"key":"key\n\t\t\t\t20170508032026_B57","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1083\/jcb.200712154","article-title":"Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system","volume":"181","author":"Zonta","year":"2008","journal-title":"J Cell Biol"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/132\/1\/260\/16695110\/awn281.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T18:38:40Z","timestamp":1557859120000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/awn281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,25]]},"references-count":57,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2008,10,25]]},"published-print":{"date-parts":[[2009,1]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awn281","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1124603.581815","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1124603.584237","asserted-by":"object"}]},"ISSN":["1460-2156","0006-8950"],"issn-type":[{"value":"1460-2156","type":"electronic"},{"value":"0006-8950","type":"print"}],"subject":[],"published":{"date-parts":[[2008,10,25]]}}}