{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T04:23:59Z","timestamp":1776399839418,"version":"3.51.2"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1093\/brain\/awr234","type":"journal-article","created":{"date-parts":[[2011,9,20]],"date-time":"2011-09-20T20:52:03Z","timestamp":1316551923000},"page":"3264-3275","source":"Crossref","is-referenced-by-count":124,"title":["Neuropathological features of corticobasal degeneration presenting as corticobasal syndrome or Richardson syndrome"],"prefix":"10.1093","volume":"134","author":[{"given":"Naomi","family":"Kouri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa E.","family":"Murray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anhar","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Rademakers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan J.","family":"Uitti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley F.","family":"Boeve","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neill R.","family":"Graff-Radford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zbigniew K.","family":"Wszolek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Litvan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith A.","family":"Josephs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis W.","family":"Dickson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2011,9,20]]},"reference":[{"key":"key\n\t\t\t\t20170425180552_awr234-B1","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1093\/brain\/awm301","article-title":"Clinical and neuropathologic features of progressive supranuclear palsy with severe pallido-nigro-luysial degeneration and axonal dystrophy","volume":"131","author":"Ahmed","year":"2008","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425180552_awr234-B2","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/ana.10793","article-title":"Identification of amino-terminally cleaved tau fragments that distinguish progressive supranuclear palsy from corticobasal degeneration","volume":"55","author":"Arai","year":"2004","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B3","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/00002093-200210000-00001","article-title":"Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank","volume":"16","author":"Barker","year":"2002","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"key\n\t\t\t\t20170425180552_awr234-B4","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1002\/ana.410400611","article-title":"Unusual clinical presentations of cortical-basal ganglionic degeneration","volume":"40","author":"Bergeron","year":"1996","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B5","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1212\/WNL.53.4.795","article-title":"Pathologic heterogeneity in clinically diagnosed corticobasal degeneration","volume":"53","author":"Boeve","year":"1999","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B6","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1002\/ana.10570","article-title":"Corticobasal degeneration and its relationship to progressive supranuclear palsy and frontotemporal dementia","volume":"54","author":"Boeve","year":"2003","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B7","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1002\/mds.10202","article-title":"Clinical correlates of the pathology underlying parkinsonism: a population perspective","volume":"17","author":"Bower","year":"2002","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t20170425180552_awr234-B8","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1001\/archneur.63.1.81","article-title":"Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy","volume":"63","author":"Boxer","year":"2006","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B9","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1111\/j.1750-3639.1999.tb00550.x","article-title":"Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's disease","volume":"9","author":"Buee","year":"1999","journal-title":"Brain Pathol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B10","doi-asserted-by":"crossref","first-page":"II6","DOI":"10.1007\/BF03161076","article-title":"Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration","volume":"246","author":"Dickson","year":"1999","journal-title":"Journal of Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B11","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1093\/jnen\/61.11.935","article-title":"Office of Rare Diseases neuropathologic criteria for corticobasal degeneration","volume":"61","author":"Dickson","year":"2002","journal-title":"J Neuropathol Exp Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B12","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/S1474-4422(09)70238-8","article-title":"Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria","volume":"8","author":"Dickson","year":"2009","journal-title":"Lancet Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B13","first-page":"1388","article-title":"Widespread cytoskeletal pathology characterizes corticobasal degeneration","volume":"146","author":"Feany","year":"1995","journal-title":"Am J Pathol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1097\/00005072-199601000-00006","article-title":"Neuropathologic overlap of progressive supranuclear palsy, Pick's disease and corticobasal degeneration","volume":"55","author":"Feany","year":"1996","journal-title":"J Neuropathol Exp Neurol"},{"issue":"Pt 5","key":"key\n\t\t\t\t20170425180552_awr234-B15","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1093\/brain\/114.5.2283","article-title":"Ageing and Parkinson's disease: substantia nigra regional selectivity","volume":"114","author":"Fearnley","year":"1991","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425180552_awr234-B16","first-page":"51","article-title":"Clinical and pathological features of corticobasal degeneration","volume":"53","author":"Gibb","year":"1990","journal-title":"Adv Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B17","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1212\/WNL.53.9.1969","article-title":"Dementia as the most common presentation of cortical-basal ganglionic degeneration","volume":"53","author":"Grimes","year":"1999","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B18","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.neuroimage.2003.09.070","article-title":"Magnetic resonance imaging-based volumetry differentiates progressive supranuclear palsy from corticobasal degeneration","volume":"21","author":"Groschel","year":"2004","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170425180552_awr234-B19","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.parkreldis.2009.11.013","article-title":"Symmetric corticobasal degeneration (S-CBD)","volume":"16","author":"Hassan","year":"2010","journal-title":"Parkinsonism Relat Disord"},{"key":"key\n\t\t\t\t20170425180552_awr234-B20","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1212\/WNL.44.11.2015","article-title":"Preliminary NINDS neuropathologic criteria for Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy)","volume":"44","author":"Hauw","year":"1994","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B21","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1093\/brain\/awf080","article-title":"The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service","volume":"125","author":"Hughes","year":"2002","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425180552_awr234-B22","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1093\/jnen\/60.6.647","article-title":"Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration","volume":"60","author":"Ishizawa","year":"2001","journal-title":"J Neuropathol Exp Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B23","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1002\/mds.10488","article-title":"Diagnostic accuracy of progressive supranuclear palsy in the Society for Progressive Supranuclear Palsy brain bank","volume":"18","author":"Josephs","year":"2003","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t20170425180552_awr234-B24","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1001\/archneur.61.12.1881","article-title":"Correlation between antemortem magnetic resonance imaging findings and pathologically confirmed corticobasal degeneration","volume":"61","author":"Josephs","year":"2004","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B25","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1212\/01.wnl.0000191307.69661.c3","article-title":"Clinicopathologic analysis of frontotemporal and corticobasal degenerations and PSP","volume":"66","author":"Josephs","year":"2006","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B26","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.neurobiolaging.2006.09.019","article-title":"Voxel-based morphometry in autopsy proven PSP and CBD","volume":"29","author":"Josephs","year":"2008","journal-title":"Neurobiol Aging"},{"key":"key\n\t\t\t\t20170425180552_awr234-B27","doi-asserted-by":"crossref","first-page":"1996","DOI":"10.1093\/brain\/awh598","article-title":"The evolution and pathology of frontotemporal dementia","volume":"128","author":"Kertesz","year":"2005","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425180552_awr234-B28","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s004010050911","article-title":"Astrocytic plaques and tufts of abnormal fibers do not coexist in corticobasal degeneration and progressive supranuclear palsy","volume":"96","author":"Komori","year":"1998","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1038\/nrneurol.2011.43","article-title":"Corticobasal degeneration: a pathologically distinct 4R tauopathy","volume":"7","author":"Kouri","year":"2011","journal-title":"Nat Rev Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B30","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1093\/brain\/awq123","article-title":"Does corticobasal degeneration exist? A clinicopathological re-evaluation","volume":"133","author":"Ling","year":"2010","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425180552_awr234-B31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1212\/WNL.47.1.1","article-title":"Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop","volume":"47","author":"Litvan","year":"1996","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B32","doi-asserted-by":"crossref","first-page":"II1","DOI":"10.1007\/BF03161075","article-title":"Clinical features differentiating patients with postmortem confirmed progressive supranuclear palsy and corticobasal degeneration","volume":"246","author":"Litvan","year":"1999","journal-title":"J Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B33","first-page":"183","article-title":"Phenotypes and prognosis: clinicopathologic studies of corticobasal degeneration","volume":"82","author":"Litvan","year":"2000","journal-title":"Adv Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B34","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1212\/01.wnl.0000259519.78480.c3","article-title":"Cognitive and motor assessment in autopsy-proven corticobasal degeneration","volume":"68","author":"Murray","year":"2007","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B35","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1001\/archneur.1968.00470310034003","article-title":"Corticodentatonigral degeneration with neuronal achromasia","volume":"18","author":"Rebeiz","year":"1968","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B36","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1212\/WNL.40.8.1203","article-title":"Cortical-basal ganglionic degeneration","volume":"40","author":"Riley","year":"1990","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B37","first-page":"29","article-title":"Clinical diagnostic criteria","volume":"82","author":"Riley","year":"2000","journal-title":"Adv Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B38","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/ana.410260107","article-title":"Dementia in Parkinson's disease is related to neuronal loss in the medial substantia nigra","volume":"26","author":"Rinne","year":"1989","journal-title":"Ann Neurol"},{"issue":"Pt 5","key":"key\n\t\t\t\t20170425180552_awr234-B39","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1093\/brain\/117.5.1183","article-title":"Corticobasal degeneration. A clinical study of 36 cases","volume":"117","author":"Rinne","year":"1994","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425180552_awr234-B40","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1046\/j.1471-4159.2002.01241.x","article-title":"Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility","volume":"83","author":"Sahara","year":"2002","journal-title":"J Neurochem"},{"key":"key\n\t\t\t\t20170425180552_awr234-B41","first-page":"192","article-title":"Corticobasal degeneration: an autopsy case clinically diagnosed as progressive supranuclear palsy","volume":"19","author":"Shiozawa","year":"2000","journal-title":"Clin Neuropathol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B42","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1750-3639.2002.tb00421.x","article-title":"Argyrophilic grain disease: neuropathology, frequency in a dementia brain bank and lack of relationship with apolipoprotein E","volume":"12","author":"Togo","year":"2002","journal-title":"Brain Pathol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B43","doi-asserted-by":"crossref","first-page":"S336","DOI":"10.1016\/S1353-8020(08)70027-0","article-title":"The many faces of corticobasal degeneration","volume":"13","author":"Wadia","year":"2007","journal-title":"Parkinsonism Relat Disord"},{"key":"key\n\t\t\t\t20170425180552_awr234-B44","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1440-1789.2003.00543.x","article-title":"Pathological heterogeneity in progressive supranuclear palsy and corticobasal degeneration","volume":"24","author":"Wakabayashi","year":"2004","journal-title":"Neuropathology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B45","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1212\/WNL.0b013e3181feb2e8","article-title":"Imaging correlates of pathology in corticobasal syndrome","volume":"75","author":"Whitwell","year":"2010","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B46","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1093\/brain\/awh488","article-title":"Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism","volume":"128","author":"Williams","year":"2005","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425180552_awr234-B47","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1002\/mds.21698","article-title":"Pure akinesia with gait freezing: a third clinical phenotype of progressive supranuclear palsy","volume":"22","author":"Williams","year":"2007","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t20170425180552_awr234-B48","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1212\/01.wnl.0000286938.39473.0e","article-title":"J. Clifford Richardson and 50 years of progressive supranuclear palsy","volume":"70","author":"Williams","year":"2008","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425180552_awr234-B49","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/mds.22977","article-title":"What features improve the accuracy of the clinical diagnosis of progressive supranuclear palsy-parkinsonism (PSP-P)?","volume":"25","author":"Williams","year":"2010","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t20170425180552_awr234-B50","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0304-3940(92)90145-W","article-title":"Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue","volume":"135","author":"Yamada","year":"1992","journal-title":"Neurosci Lett"},{"key":"key\n\t\t\t\t20170425180552_awr234-B51","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1001\/archneur.55.5.609","article-title":"Atrophy of the corpus callosum, cortical hypometabolism, and cognitive impairment in corticobasal degeneration","volume":"55","author":"Yamauchi","year":"1998","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170425180552_awr234-B52","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1136\/jnnp.69.5.623","article-title":"Comparison of the pattern of atrophy of the corpus callosum in frontotemporal dementia, progressive supranuclear palsy, and Alzheimer's disease","volume":"69","author":"Yamauchi","year":"2000","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/134\/11\/3264\/13795036\/awr234.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T15:56:21Z","timestamp":1503417381000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/awr234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,20]]},"references-count":52,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2011,9,20]]},"published-print":{"date-parts":[[2011,11]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awr234","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.13393979.14762087","asserted-by":"object"}]},"ISSN":["1460-2156","0006-8950"],"issn-type":[{"value":"1460-2156","type":"electronic"},{"value":"0006-8950","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9,20]]}}}