{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:55:13Z","timestamp":1791334513516,"version":"4.3.1"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1093\/brain\/awt212","type":"journal-article","created":{"date-parts":[[2013,9,6]],"date-time":"2013-09-06T22:51:32Z","timestamp":1378507892000},"page":"3151-3162","source":"Crossref","is-referenced-by-count":389,"title":["Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype"],"prefix":"10.1093","volume":"136","author":[{"given":"Sarosh R.","family":"Irani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte J.","family":"Stagg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan M.","family":"Schott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clive R.","family":"Rosenthal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne A.","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippa","family":"Pettingill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary","family":"Pettingill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Waters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie L.","family":"Voets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel J.","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Cash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily N.","family":"Manning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bethan","family":"Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shelagh J. M.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Vincent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,9,6]]},"reference":[{"key":"key\n\t\t\t\t20170425181220_awt212-B1","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1212\/WNL.0b013e3182152808","article-title":"Tonic seizures: a diagnostic clue of anti-LGI1 encephalitis?","volume":"76","author":"Andrade","year":"2011","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425181220_awt212-B2","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1001\/archneurol.2010.317","article-title":"Kinesigenic dyskinesia in a case of voltage-gated potassium channel-complex protein antibody encephalitis","volume":"68","author":"Aradillas","year":"2011","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B3","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1528-1167.2009.02287.x","article-title":"Adult-onset drug-refractory seizure disorder associated with anti-voltage-gated potassium-channel antibody","volume":"51","author":"Barajas","year":"2010","journal-title":"Epilepsia"},{"key":"key\n\t\t\t\t20170425181220_awt212-B4","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1136\/jnnp-2011-301506","article-title":"Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia","volume":"83","author":"Becker","year":"2012","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key\n\t\t\t\t20170425181220_awt212-B5","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1212\/01.wnl.0000276946.08412.ef","article-title":"Limbic encephalitis as a precipitating event in adult-onset temporal lobe epilepsy","volume":"69","author":"Bien","year":"2007","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425181220_awt212-B41","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1093\/brain\/aws082","article-title":"Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis","volume":"135","author":"Bien","year":"2012","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425181220_awt212-B6","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/ana.1097","article-title":"Potassium channel antibodies in two patients with reversible limbic encephalitis","volume":"50","author":"Buckley","year":"2001","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B7","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.media.2013.02.006","article-title":"Alzheimer's disease neuroimaging initiative. STEPS: similarity and truth estimation for propagated segmentations and its application to hippocampal segmentation and brain parcelation","volume":"17","author":"Cardoso","year":"2013","journal-title":"Medical Image Analysis"},{"key":"key\n\t\t\t\t20170425181220_awt212-B8","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1093\/brain\/awq171","article-title":"Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice","volume":"133","author":"Chabrol","year":"2010","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425181220_awt212-B9","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1001\/archneur.64.3.404","article-title":"Extensive and temporally ungraded retrograde amnesia in encephalitis associated with antibodies to voltage-gated potassium channels","volume":"64","author":"Chan","year":"2007","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B10","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S1474-4422(08)70224-2","article-title":"Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies","volume":"7","author":"Dalmau","year":"2008","journal-title":"Lancet Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B11","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1001\/archneur.65.10.1341","article-title":"Voltage-gated potassium channel autoimmunity mimicking creutzfeldt-jakob disease","volume":"65","author":"Geschwind","year":"2008","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B12","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1136\/jnnp.2003.034447","article-title":"Recommended diagnostic criteria for paraneoplastic neurological syndromes","volume":"75","author":"Graus","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key\n\t\t\t\t20170425181220_awt212-B13","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1002\/ana.410410215","article-title":"Autoantibodies detected to expressed K+ channels are implicated in neuromyotonia","volume":"41","author":"Hart","year":"1997","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B14","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1212\/01.wnl.0000326572.93762.51","article-title":"Immunotherapy-responsive seizure-like episodes with potassium channel antibodies","volume":"71","author":"Irani","year":"2008","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425181220_awt212-B15","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1093\/brain\/awq213","article-title":"Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia","volume":"133","author":"Irani","year":"2010","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425181220_awt212-B16","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1093\/brain\/awq113","article-title":"N-methyl-d-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes","volume":"133","author":"Irani","year":"2010","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425181220_awt212-B17","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1002\/ana.22307","article-title":"Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis","volume":"69","author":"Irani","year":"2011","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B18","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/ana.23577","article-title":"Morvan syndrome: clinical and serological observations in 29 cases","volume":"72","author":"Irani","year":"2012","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B19","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1007\/s11064-011-0413-6","article-title":"Hydrocortisone enhances the function of the blood-nerve barrier through the up-regulation of claudin-5","volume":"36","author":"Kashiwamura","year":"2011","journal-title":"Neurochem Res"},{"key":"key\n\t\t\t\t20170425181220_awt212-B20","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1212\/WNL.0b013e3182698cab","article-title":"Chronic pain as a manifestation of potassium channel-complex autoimmunity","volume":"79","author":"Klein","year":"2012","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425181220_awt212-B21","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/S1474-4422(10)70137-X","article-title":"Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series","volume":"9","author":"Lai","year":"2010","journal-title":"Lancet Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B22","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1528-1167.2010.02756.x","article-title":"Human limbic encephalitis serum enhances hippocampal mossy fiber-CA3 pyramidal cell synaptic transmission","volume":"52","author":"Lalic","year":"2010","journal-title":"Epilepsia"},{"key":"key\n\t\t\t\t20170425181220_awt212-B23","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/j.neuroimage.2010.12.067","article-title":"Brain MAPS: an automated, accurate and robust brain extraction technique using a template library","volume":"55","author":"Leung","year":"2011","journal-title":"NeuroImage"},{"key":"key\n\t\t\t\t20170425181220_awt212-B24","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1093\/brain\/124.12.2417","article-title":"Morvan's syndrome: peripheral and central nervous system and cardiac involvement with antibodies to voltage-gated potassium channels","volume":"124","author":"Liguori","year":"2001","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425181220_awt212-B25","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1002\/gps.1610","article-title":"The Addenbrooke's cognitive examination revised (ACE-R): a brief cognitive test battery for dementia screening","volume":"21","author":"Mioshi","year":"2006","journal-title":"Int J Geriatr Psychiatry"},{"key":"key\n\t\t\t\t20170425181220_awt212-B26","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1093\/hmg\/11.9.1119","article-title":"Mutations in the LGI1\/Epitempin gene on 10q24 cause autosomal dominant lateral temporal epilepsy","volume":"11","author":"Morante-Redolat","year":"2002","journal-title":"Hum Mol Genet"},{"key":"key\n\t\t\t\t20170425181220_awt212-B27","article-title":"Faciobrachial dystonic seizures without voltage gated potassium channel (VGKC) antibodies\u2013Seizure or paroxysmal movement disorder?","volume":"27","author":"O\u2019Connell","year":"2012","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t20170425181220_awt212-B28","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1001\/archneurol.2011.2985","article-title":"Autoimmune epilepsy: clinical characteristics and response to immunotherapy","volume":"69","author":"Quek","year":"2012","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B29","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/S0140-6736(03)12983-2","article-title":"Amnesia, cerebral atrophy, and autoimmunity","volume":"361","author":"Schott","year":"2003","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170425181220_awt212-B30","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.neuron.2006.01.033","article-title":"The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1","volume":"49","author":"Schulte","year":"2006","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170425181220_awt212-B31","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1109\/42.668698","article-title":"A nonparametric method for automatic correction of intensity nonuniformity in MRI data","volume":"17","author":"Sled","year":"1998","journal-title":"IEEE Trans Med Imaging"},{"key":"key\n\t\t\t\t20170425181220_awt212-B32","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0896-6273(00)81018-1","article-title":"Deletion of the K(V)1.1 potassium channel causes epilepsy in mice","volume":"20","author":"Smart","year":"1998","journal-title":"Neuron"},{"key":"key\n\t\t\t\t20170425181220_awt212-B33","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/ana.22470","article-title":"Faciobrachial dystonic attacks: seizures or movement disorder?","volume":"70","author":"Striano","year":"2011","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B34","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1212\/01.wnl.0000312275.04260.a0","article-title":"Clinical spectrum of voltage-gated potassium channel autoimmunity","volume":"70","author":"Tan","year":"2008","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425181220_awt212-B35","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1212\/01.WNL.0000122648.19196.02","article-title":"Potentially reversible autoimmune limbic encephalitis with neuronal potassium channel antibody","volume":"62","author":"Thieben","year":"2004","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425181220_awt212-B36","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1007\/s00234-006-0069-0","article-title":"Serial MRI of limbic encephalitis","volume":"48","author":"Urbach","year":"2006","journal-title":"Neuroradiology"},{"key":"key\n\t\t\t\t20170425181220_awt212-B37","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.neuroimage.2007.12.025","article-title":"Brain morphometry with multiecho MPRAGE","volume":"40","author":"van der Kouwe","year":"2008","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170425181220_awt212-B38","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S1474-4422(11)70096-5","article-title":"Autoantibodies associated with diseases of the CNS: new developments and future challenges","volume":"10","author":"Vincent","year":"2011","journal-title":"Lancet Neurol"},{"key":"key\n\t\t\t\t20170425181220_awt212-B39","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1093\/brain\/awh077","article-title":"Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis","volume":"127","author":"Vincent","year":"2004","journal-title":"Brain"},{"key":"key\n\t\t\t\t20170425181220_awt212-B40","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1136\/jnnp-2011-301237","article-title":"Central nervous system neuronal surface antibody associated syndromes: review and guidelines for recognition","volume":"83","author":"Zuliani","year":"2012","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/136\/10\/3151\/13795579\/awt212.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T16:07:08Z","timestamp":1503418028000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/awt212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,6]]},"references-count":41,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2013,9,6]]},"published-print":{"date-parts":[[2013,10]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awt212","relation":{},"ISSN":["1460-2156","0006-8950"],"issn-type":[{"value":"1460-2156","type":"electronic"},{"value":"0006-8950","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9,6]]}}}