{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T08:39:04Z","timestamp":1789979944613,"version":"4.0.1"},"reference-count":80,"publisher":"Oxford University Press (OUP)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1093\/brain\/awu298","type":"journal-article","created":{"date-parts":[[2014,11,3]],"date-time":"2014-11-03T23:05:46Z","timestamp":1415055946000},"page":"3339-3354","source":"Crossref","is-referenced-by-count":46,"title":["White matter involvement in sporadic Creutzfeldt-Jakob disease"],"prefix":"10.1093","volume":"137","author":[{"given":"Eduardo","family":"Caverzasi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Luisa","family":"Mandelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"DeArmond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher P.","family":"Hess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Vitali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nico","family":"Papinutto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abby","family":"Oehler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce L.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina V.","family":"Lobach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Bastianello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Geschwind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland G.","family":"Henry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,11,3]]},"reference":[{"key":"key\n\t\t\t\t20170425190243_awu298-B1","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.3174\/ajnr.A2105","article-title":"Assessment of white matter tract damage in patients with amyotrophic lateral sclerosis: a diffusion tensor MR imaging tractography study","volume":"31","author":"Agosta","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B2","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1148\/radiol.10101284","article-title":"White matter damage in Alzheimer disease and its relationship to gray matter atrophy","volume":"258","author":"Agosta","year":"2011","journal-title":"Radiology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B3","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1212\/WNL.46.4.1123","article-title":"Demyelinating peripheral neuropathy with Creutzfeldt-Jakob disease and mutation at codon 200 of the prion protein gene","volume":"46","author":"Antoine","year":"1996","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B4","first-page":"284","article-title":"Spatial patterns of the vacuolation in subcortical white matter in sporadic Creutzfeldt-Jakob disease (sCJD)","volume":"21","author":"Armstrong","year":"2002","journal-title":"Clin Neuropathol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B5","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1097\/NEN.0b013e3182544680","article-title":"A brain aggregate model gives new insights into the pathobiology and treatment of prion diseases","volume":"71","author":"Bajsarowicz","year":"2012","journal-title":"J Neuropathol Exp Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B6","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1093\/jnen\/63.8.882","article-title":"The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system","volume":"63","author":"Bouzamondo-Bernstein","year":"2004","journal-title":"J Neuropathol Exp Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B7","doi-asserted-by":"crossref","first-page":"13148","DOI":"10.1073\/pnas.93.23.13148","article-title":"Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system","volume":"93","author":"Brandner","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170425190243_awu298-B8","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/nn.2483","article-title":"Axonal prion protein is required for peripheral myelin maintenance","volume":"13","author":"Bremer","year":"2010","journal-title":"Nat Neurosci"},{"key":"key\n\t\t\t\t20170425190243_awu298-B9","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.nbd.2007.04.001","article-title":"MRI and MRS alterations in the preclinical phase of murine prion disease: association with neuropathological and behavioural changes","volume":"26","author":"Broom","year":"2007","journal-title":"Neurobiol Dis"},{"key":"key\n\t\t\t\t20170425190243_awu298-B10","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1002\/ana.410200507","article-title":"Creutzfeldt-Jakob disease: clinical analysis of a consecutive series of 230 neuropathologically verified cases","volume":"20","author":"Brown","year":"1986","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B11","first-page":"172","article-title":"Chapter 6. Creutzfeldt-Jakob disease: astrocytosis and spongiform changes of the white matter","volume-title":"Unconventional virus diseases of the central nervous system","author":"Bugiani","year":"1989"},{"key":"key\n\t\t\t\t20170425190243_awu298-B12","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.3174\/ajnr.A2469","article-title":"The topography of brain microstructural damage in amyotrophic lateral sclerosis assessed using diffusion tensor MR imaging","volume":"32","author":"Canu","year":"2011","journal-title":"AJNR Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B13","first-page":"125","article-title":"A panencephalopathic type of Creutzfeldt-Jakob disease with selective lesions of the thalamic nuclei in 2 Swiss patients","volume":"15","author":"Carota","year":"1996","journal-title":"Clin Neuropathol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B14","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.nicl.2014.01.011","article-title":"Application of quantitative DTI metrics in sporadic CJD","volume":"4","author":"Caverzasi","year":"2014","journal-title":"Neuroimage Clin"},{"key":"key\n\t\t\t\t20170425190243_awu298-B15","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1212\/WNL.48.5_Suppl_6.10S","article-title":"The Neuropsychiatric Inventory: assessing psychopathology in dementia patients","volume":"48","author":"Cummings","year":"1997","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B16","first-page":"179","article-title":"Cortical surface-based analysis","volume":"9","author":"Dale","year":"1999","journal-title":"I. Segmentation and surface reconstruction. Neuroimage"},{"key":"key\n\t\t\t\t20170425190243_awu298-B17","first-page":"273","article-title":"Prion diseases","volume-title":"Greenfield\u0301s neuropathology","author":"DeArmond","year":"2002","edition":"7th edn"},{"key":"key\n\t\t\t\t20170425190243_awu298-B18","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1101\/SQB.1996.061.01.053","article-title":"Abnormal plasma membrane properties and functions in prion-infected cell lines","volume":"61","author":"DeArmond","year":"1996","journal-title":"Cold Spring Harb Symp Quant Biol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B19","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1186\/1471-2377-12-144","article-title":"Spreading brain lesions in a familial Creutzfeldt-Jakob disease with V180I mutation over 4 years","volume":"12","author":"Deguchi","year":"2012","journal-title":"BMC Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B20","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1212\/WNL.52.1.205","article-title":"Diffusion-weighted MRI in sporadic Creutzfeldt-Jakob disease","volume":"52","author":"Demaerel","year":"1999","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B21","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1006\/nimg.1998.0396","article-title":"Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system","volume":"9","author":"Fischl","year":"1999","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170425190243_awu298-B22","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/0006-8993(85)91091-1","article-title":"Targeting of scrapie lesions and spread of agent via the retino-tectal projection","volume":"346","author":"Fraser","year":"1985","journal-title":"Brain Res"},{"key":"key\n\t\t\t\t20170425190243_awu298-B23","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.mri.2006.07.001","article-title":"The imaging appearance of Creutzfeldt-Jakob disease caused by the E200K mutation","volume":"24","author":"Fulbright","year":"2006","journal-title":"Magn Reson Imaging"},{"key":"key\n\t\t\t\t20170425190243_awu298-B24","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.3174\/ajnr.A2069","article-title":"Combined diffusion imaging and MR spectroscopy in the diagnosis of human prion diseases","volume":"31","author":"Galanaud","year":"2010","journal-title":"AJNR Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B25","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/0192623310389621","article-title":"Histology of the central nervous system","volume":"39","author":"Garman","year":"2011","journal-title":"Toxic Path"},{"key":"key\n\t\t\t\t20170425190243_awu298-B26","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.ncl.2007.04.001","article-title":"Rapidly progressive dementia","volume":"25","author":"Geschwind","year":"2007","journal-title":"Neurol Clin"},{"key":"key\n\t\t\t\t20170425190243_awu298-B27","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/WAD.0b013e31818323ef","article-title":"Correlating DWI MRI with pathologic and other features of Jakob-Creutzfeldt disease","volume":"23","author":"Geschwind","year":"2009","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"key\n\t\t\t\t20170425190243_awu298-B28","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1212\/WNL.51.1.271","article-title":"Creutzfeldt-Jakob disease with long duration and panencephalopathic lesions: molecular analysis of one case","volume":"51","author":"Ghorayeb","year":"1998","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B29","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/BF00143125","article-title":"Creutzfeldt-Jacob disease associated with the PRNP codon 200Lys mutation: an analysis of 45 families","volume":"7","author":"Goldfarb","year":"1991","journal-title":"Eur J Epidemiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B30","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1002\/ana.10195","article-title":"Prion protein deposits match magnetic resonance imaging signal abnormalities in Creutzfeldt-Jakob disease","volume":"51","author":"Haik","year":"2002","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B31","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/j.1440-1789.2009.01016.x","article-title":"An autopsied case of panencephalopathic-type Creutzfeldt-Jakob disease with mutation in the prion protein gene at codon 232 and type 1 prion protein","volume":"29","author":"Hama","year":"2009","journal-title":"Neuropathology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B32","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s00401-006-0111-7","article-title":"Clinicopathologic characteristics of sporadic Japanese Creutzfeldt-Jakob disease classified according to prion protein gene polymorphism and prion protein type","volume":"112","author":"Iwasaki","year":"2006","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B33","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1365-2990.2008.01004a.x","article-title":"Panencephalopathic Creutzfeldt-Jakob disease in the Netherlands and the UK: clinical and pathological characteristics of nine patients","volume":"35","author":"Jansen","year":"2009","journal-title":"Neuropathol Appl Neurobiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B34","doi-asserted-by":"crossref","first-page":"20026","DOI":"10.1074\/jbc.M109218200","article-title":"Macrophage\/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma -dependent pathway","volume":"277","author":"Kanazawa","year":"2002","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170425190243_awu298-B35","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/BF01310854","article-title":"The antiviral compound HPA-23 can prevent scrapie when administered at the time of infection","volume":"78","author":"Kimberlin","year":"1983","journal-title":"Arch Virol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B36","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1007\/s004010051124","article-title":"Deposition of the prion protein (PrP) during the evolution of experimental Creutzfeldt-Jakob disease","volume":"98","author":"Kordek","year":"1999","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B37","doi-asserted-by":"crossref","first-page":"e30756","DOI":"10.1371\/journal.pone.0030756","article-title":"CD36 participates in PrP(106-126)-induced activation of microglia","volume":"7","author":"Kouadir","year":"2012","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20170425190243_awu298-B38","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1001\/archneur.1996.00550090125018","article-title":"Diagnostic criteria for sporadic Creutzfeldt-Jakob disease","volume":"53","author":"Kretzschmar","year":"1996","journal-title":"Arch Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B39","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1159\/000117324","article-title":"Panencephalopathic type of Creutzfeldt-Jakob disease with primary extensive involvement of white matter","volume":"30","author":"Kruger","year":"1990","journal-title":"Eur Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B40","first-page":"905","article-title":"Primary white matter involvement in sporadic-type Creutzfeldt-Jakob disease? Which came first, the chicken or the egg?","volume":"25","author":"Kucharczyk","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B41","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.3174\/ajnr.A3125","article-title":"Cerebral white matter disruption in Creutzfeldt-Jakob disease","volume":"33","author":"Lee","year":"2012","journal-title":"AJNR Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B42","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s004010050995","article-title":"Neuroaxonal pathology in Creutzfeldt-Jakob disease","volume":"97","author":"Liberski","year":"1999","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B43","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00308949","article-title":"White matter ultrastructural pathology of experimental Creutzfeldt-Jakob disease in mice","volume":"79","author":"Liberski","year":"1989","journal-title":"Acta Neuropathol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B44","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.lfs.2011.05.011","article-title":"Cross talk between activation of microglia and astrocytes in pathological conditions in the central nervous system","volume":"89","author":"Liu","year":"2011","journal-title":"Life Sci"},{"key":"key\n\t\t\t\t20170425190243_awu298-B45","first-page":"61","article-title":"Functional evaluation: Barthel Index","volume":"14","author":"Mahoney","year":"1965","journal-title":"Md State Med J"},{"key":"key\n\t\t\t\t20170425190243_awu298-B46","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1212\/WNL.0b013e3181a18846","article-title":"Pathologic correlates of diffusion MRI changes in Creutzfeldt-Jakob disease","volume":"72","author":"Manners","year":"2009","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B47","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1523\/JNEUROSCI.4303-03.2004","article-title":"Neurons and astrocytes respond to prion infection by inducing microglia recruitment","volume":"24","author":"Marella","year":"2004","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170425190243_awu298-B48","first-page":"910","article-title":"White matter lesions in panencephalopathic type of Creutzfeldt-Jakob disease: MR imaging and pathologic correlations","volume":"25","author":"Matsusue","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B49","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1212\/WNL.0b013e3181a96e5d","article-title":"MRI lesion profiles in sporadic Creutzfeldt-Jakob disease","volume":"72","author":"Meissner","year":"2009","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B50","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1523\/JNEUROSCI.04-02-00585.1984","article-title":"Fibrous and protoplasmic astrocytes are biochemically and developmentally distinct","volume":"4","author":"Miller","year":"1984","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170425190243_awu298-B51","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1136\/jnnp.44.2.103","article-title":"Panencephalopathic type of Creutzfeldt-Jakob disease: primary involvement of the cerebral white matter","volume":"44","author":"Mizutani","year":"1981","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key\n\t\t\t\t20170425190243_awu298-B52","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1365-2990.1995.tb01097.x","article-title":"Reactive microglia in Creutzfeldt-Jakob disease","volume":"21","author":"Muhleisen","year":"1995","journal-title":"Neuropathol Appl Neurobiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B53","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1159\/000254842","article-title":"Familial Creutzfeldt-Jakob disease with a V180I mutation: comparative analysis with pathological findings and diffusion-weighted images","volume":"28","author":"Mutsukura","year":"2009","journal-title":"Dement Geriatr Cogn Disord"},{"key":"key\n\t\t\t\t20170425190243_awu298-B54","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1369\/jhc.3A6213.2004","article-title":"Differential expression of apolipoprotein D in human astroglial and oligodendroglial cells","volume":"52","author":"Navarro","year":"2004","journal-title":"J Histochem Cytochem"},{"key":"key\n\t\t\t\t20170425190243_awu298-B55","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1002\/mus.880151103","article-title":"Demyelinating peripheral neuropathy in Creutzfeldt-Jakob disease","volume":"15","author":"Neufeld","year":"1992","journal-title":"Muscle Nerve"},{"key":"key\n\t\t\t\t20170425190243_awu298-B56","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1161\/01.STR.0000038424.70926.5E","article-title":"Visual rating scales for age-related white matter changes (leukoaraiosis): can the heterogeneity be reduced?","volume":"33","author":"Pantoni","year":"2002","journal-title":"Stroke"},{"key":"key\n\t\t\t\t20170425190243_awu298-B57","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1002\/1531-8249(199908)46:2<224::AID-ANA12>3.0.CO;2-W","article-title":"Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects","volume":"46","author":"Parchi","year":"1999","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B58","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1006\/nimg.2001.0765","article-title":"Water diffusion changes in Wallerian degeneration and their dependence on white matter architecture","volume":"13","author":"Pierpaoli","year":"2001","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170425190243_awu298-B59","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/nn0310-275","article-title":"Myelin maintenance: axonal support required","volume":"13","author":"Popko","year":"2010","journal-title":"Nat Neurosci"},{"key":"key\n\t\t\t\t20170425190243_awu298-B60","doi-asserted-by":"crossref","first-page":"13363","DOI":"10.1073\/pnas.95.23.13363","article-title":"Prions","volume":"95","author":"Prusiner","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170425190243_awu298-B61","doi-asserted-by":"crossref","first-page":"4879","DOI":"10.1523\/JNEUROSCI.0328-05.2005","article-title":"Truncated prion protein and Doppel are myelinotoxic in the absence of oligodendrocytic PrPC","volume":"25","author":"Radovanovic","year":"2005","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170425190243_awu298-B62","doi-asserted-by":"crossref","first-page":"6057","DOI":"10.1093\/emboj\/16.20.6057","article-title":"Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie","volume":"16","author":"Raeber","year":"1997","journal-title":"EMBO J"},{"key":"key\n\t\t\t\t20170425190243_awu298-B63","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1073\/pnas.0409651102","article-title":"Diagnosis of human prion disease","volume":"102","author":"Safar","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170425190243_awu298-B64","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1159\/000107082","article-title":"Total tau protein in cerebrospinal fluid and diffusion-weighted MRI as an early diagnostic marker for Creutzfeldt-Jakob disease","volume":"24","author":"Satoh","year":"2007","journal-title":"Dement Geriatr Cogn Disord"},{"key":"key\n\t\t\t\t20170425190243_awu298-B65","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0022-510X(93)90041-V","article-title":"A semiquantative rating scale for the assessment of signal hyperintensities on magnetic resonance imaging","volume":"114","author":"Scheltens","year":"1993","journal-title":"J Neurol Sci"},{"key":"key\n\t\t\t\t20170425190243_awu298-B66","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s10654-012-9660-3","article-title":"Clinical aspects of common genetic Creutzfeldt-Jakob disease","volume":"27","author":"Schelzke","year":"2012","journal-title":"Eur J Epidemiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B67","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1212\/01.WNL.0000134555.59460.5D","article-title":"Diffusion-weighted MRI abnormalities as an early diagnostic marker for Creutzfeldt-Jakob disease","volume":"63","author":"Shiga","year":"2004","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B68","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/S0022-510X(96)00198-0","article-title":"Panencephalitic Creutzfeldt-Jakob disease in a Chinese family. Unusual presentation with PrP codon 210 mutation and identification by PCR-SSCP","volume":"143","author":"Shyu","year":"1996","journal-title":"J Neurol Sci"},{"key":"key\n\t\t\t\t20170425190243_awu298-B69","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1016\/j.neuroimage.2006.02.024","article-title":"Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data","volume":"31","author":"Smith","year":"2006","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170425190243_awu298-B70","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1006\/nimg.2002.1267","article-title":"Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water","volume":"17","author":"Song","year":"2002","journal-title":"Neuroimage"},{"key":"key\n\t\t\t\t20170425190243_awu298-B71","doi-asserted-by":"crossref","first-page":"10595","DOI":"10.1073\/pnas.0803671105","article-title":"A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains","volume":"105","author":"Spilman","year":"2008","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170425190243_awu298-B72","doi-asserted-by":"crossref","first-page":"7620","DOI":"10.1073\/pnas.89.16.7620","article-title":"Regional mapping of prion proteins in brain","volume":"89","author":"Taraboulos","year":"1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170425190243_awu298-B73","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.3174\/ajnr.A0496","article-title":"Pattern of cortical changes in sporadic Creutzfeldt-Jakob disease","volume":"28","author":"Tschampa","year":"2007","journal-title":"AJNR Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B74","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1212\/WNL.0b013e31821a4439","article-title":"Diffusion-weighted MRI hyperintensity patterns differentiate CJD from other rapid dementias","volume":"76","author":"Vitali","year":"2011","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20170425190243_awu298-B75","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1007\/s00415-012-6664-6","article-title":"Role of magnetic resonance imaging, cerebrospinal fluid, and electroencephalogram in diagnosis of sporadic Creutzfeldt-Jakob disease","volume":"260","author":"Wang","year":"2013","journal-title":"J Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B76","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/j.1365-2796.2009.02200.x","article-title":"Neuroimaging in acute ischaemic stroke: insights into unanswered questions of pathophysiology","volume":"267","author":"Wardlaw","year":"2010","journal-title":"J Intern Med"},{"key":"key\n\t\t\t\t20170425190243_awu298-B77","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1006\/exnr.1997.6424","article-title":"PrP deposition, microglial activation, and neuronal apoptosis in murine scrapie","volume":"144","author":"Williams","year":"1997","journal-title":"Exp Neurol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B78","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1136\/jnnp.63.4.524","article-title":"Panencephalopathic type of Creutzfeldt-Jakob disease associated with cadaveric dura mater graft","volume":"63","author":"Yamada","year":"1997","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key\n\t\t\t\t20170425190243_awu298-B79","first-page":"1551","article-title":"Diffusion-weighted and fluid-attenuated inversion recovery imaging in Creutzfeldt-Jakob disease: high sensitivity and specificity for diagnosis","volume":"26","author":"Young","year":"2005","journal-title":"AJNR Am J Neuroradiol"},{"key":"key\n\t\t\t\t20170425190243_awu298-B80","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1093\/brain\/awp191","article-title":"Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease","volume":"132","author":"Zerr","year":"2009","journal-title":"Brain"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/137\/12\/3339\/13799793\/awu298.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,16]],"date-time":"2019-08-16T20:13:02Z","timestamp":1565986382000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/awu298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,3]]},"references-count":80,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2014,11,3]]},"published-print":{"date-parts":[[2014,12]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awu298","relation":{},"ISSN":["1460-2156","0006-8950"],"issn-type":[{"value":"1460-2156","type":"electronic"},{"value":"0006-8950","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11,3]]}}}