{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:23:38Z","timestamp":1790375018184,"version":"4.1.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1093\/brain\/awv234","type":"journal-article","created":{"date-parts":[[2015,8,21]],"date-time":"2015-08-21T21:41:09Z","timestamp":1440193269000},"page":"3100-3109","source":"Crossref","is-referenced-by-count":40,"title":["Closing the tau loop: the missing tau mutation"],"prefix":"10.1093","volume":"138","author":[{"given":"Allan","family":"McCarthy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roisin","family":"Lonergan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana A.","family":"Olszewska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"O\u2019Dowd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gemma","family":"Cummins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Magennis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emer M.","family":"Fallon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niall","family":"Pender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward D.","family":"Huey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Cosentino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Killian","family":"O\u2019Rourke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan D.","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"O\u2019Connell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Delon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Farrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Grazia","family":"Spillantini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis P.","family":"Rowland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley","family":"Fahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Craig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hutton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Lynch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,8,21]]},"reference":[{"key":"2015100801173470000_138.10.3100.1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05016"},{"key":"2015100801173470000_138.10.3100.2","doi-asserted-by":"publisher","DOI":"10.1007\/s10048-008-0127-3"},{"key":"2015100801173470000_138.10.3100.3","doi-asserted-by":"publisher","DOI":"10.1177\/1533317513488918"},{"key":"2015100801173470000_138.10.3100.4","doi-asserted-by":"publisher","DOI":"10.1038\/nature05017"},{"key":"2015100801173470000_138.10.3100.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.09.011"},{"key":"2015100801173470000_138.10.3100.6","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5492-06.2007"},{"key":"2015100801173470000_138.10.3100.7","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(89)90210-9"},{"key":"2015100801173470000_138.10.3100.8","doi-asserted-by":"crossref","first-page":"4225","DOI":"10.1002\/j.1460-2075.1990.tb07870.x","article-title":"Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization","volume":"9","author":"Goedert","year":"1990","journal-title":"EMBO J"},{"key":"2015100801173470000_138.10.3100.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2004.08.007"},{"key":"2015100801173470000_138.10.3100.10","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.21.15134"},{"key":"2015100801173470000_138.10.3100.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(98)01217-4"},{"key":"2015100801173470000_138.10.3100.12","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200004)47:4<417::AID-ANA1>3.0.CO;2-B"},{"key":"2015100801173470000_138.10.3100.13","doi-asserted-by":"publisher","DOI":"10.1038\/31508"},{"key":"2015100801173470000_138.10.3100.14","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199902250-00010"},{"key":"2015100801173470000_138.10.3100.15","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.01149-10"},{"key":"2015100801173470000_138.10.3100.16","first-page":"535","article-title":"A novel mutation at position +11 in the intron following exon 10 of the tau gene in FTDP-17","volume":"43","author":"Kowalska","year":"2002","journal-title":"J Appl Genet"},{"key":"2015100801173470000_138.10.3100.17","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.8.1169"},{"key":"2015100801173470000_138.10.3100.18","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.10.1878"},{"key":"2015100801173470000_138.10.3100.19","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601878"},{"key":"2015100801173470000_138.10.3100.20","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1083"},{"key":"2015100801173470000_138.10.3100.21","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3463-09.2009"},{"key":"2015100801173470000_138.10.3100.22","doi-asserted-by":"publisher","DOI":"10.1042\/BST0330595"},{"key":"2015100801173470000_138.10.3100.23","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(99)00294-X"},{"key":"2015100801173470000_138.10.3100.24","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.6.1546"},{"key":"2015100801173470000_138.10.3100.25","doi-asserted-by":"crossref","first-page":"923","DOI":"10.3233\/JAD-2012-121393","article-title":"The ELISA-measured increase in cerebrospinal fluid tau that discriminates Alzheimer's disease from other neurodegenerative disorders is not attributable to differential recognition of tau assembly forms","volume":"33","author":"O'Dowd","year":"2013","journal-title":"J Alzheimers Dis"},{"key":"2015100801173470000_138.10.3100.26","doi-asserted-by":"publisher","DOI":"10.3109\/09540261.2013.776523"},{"key":"2015100801173470000_138.10.3100.27","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf069"},{"key":"2015100801173470000_138.10.3100.28","doi-asserted-by":"publisher","DOI":"10.1097\/NEN.0000000000000182"},{"key":"2015100801173470000_138.10.3100.29","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-013-1411-2"},{"key":"2015100801173470000_138.10.3100.30","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awr179"},{"key":"2015100801173470000_138.10.3100.31","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.09.010"},{"key":"2015100801173470000_138.10.3100.32","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.6.884"},{"key":"2015100801173470000_138.10.3100.33","doi-asserted-by":"publisher","DOI":"10.1086\/302256"},{"key":"2015100801173470000_138.10.3100.34","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e32834cd442"},{"key":"2015100801173470000_138.10.3100.35","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410390609"},{"key":"2015100801173470000_138.10.3100.36","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S1474-4422(13)70090-5","article-title":"Tau pathology and neurodegeneration","volume":"6","author":"Spillantini","year":"2013","journal-title":"Lancet Neurol"},{"key":"2015100801173470000_138.10.3100.37","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.13.7737"},{"key":"2015100801173470000_138.10.3100.38","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.5.880"},{"key":"2015100801173470000_138.10.3100.39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2013.03.015"},{"key":"2015100801173470000_138.10.3100.40","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.3.710"},{"key":"2015100801173470000_138.10.3100.41","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2008.03.002"},{"key":"2015100801173470000_138.10.3100.42","first-page":"1159","article-title":"Localization of disinhibition-dementia-parkinsonism-amyotrophy complex to 17q21-22","volume":"55","author":"Wilhelmsen","year":"1994","journal-title":"Am J Hum Genet"},{"key":"2015100801173470000_138.10.3100.43","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws001"},{"key":"2015100801173470000_138.10.3100.44","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200004)47:4<422::AID-ANA4>3.0.CO;2-G"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/138\/10\/3100\/13798831\/awv234.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T14:15:35Z","timestamp":1567088135000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/awv234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,21]]},"references-count":44,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2015,9,25]]},"published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1093\/brain\/awv234"],"URL":"https:\/\/doi.org\/10.1093\/brain\/awv234","relation":{},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,21]]}}}