{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:52:11Z","timestamp":1790776331366,"version":"4.1.0"},"reference-count":63,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1093\/brain\/aww036","type":"journal-article","created":{"date-parts":[[2016,3,8]],"date-time":"2016-03-08T22:14:50Z","timestamp":1457475290000},"page":"1587-1604","source":"Crossref","is-referenced-by-count":37,"title":["A subcutaneous cellular implant for passive immunization against amyloid-\u03b2 reduces brain amyloid and tau pathologies"],"prefix":"10.1093","volume":"139","author":[{"given":"Aur\u00e9lien","family":"Lathuili\u00e8re","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Laversenne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Astolfo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erhard","family":"Kopetzki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Jacobsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Stampanoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Bohrmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard L.","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Aebischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,3,8]]},"reference":[{"key":"2016042702422984000_139.5.1587.1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4742-11.2012"},{"key":"2016042702422984000_139.5.1587.2","doi-asserted-by":"publisher","DOI":"10.1038\/nm0696-696"},{"key":"2016042702422984000_139.5.1587.3","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(96)00101-0"},{"key":"2016042702422984000_139.5.1587.4","doi-asserted-by":"publisher","DOI":"10.1039\/c3nr34089a"},{"key":"2016042702422984000_139.5.1587.5","doi-asserted-by":"crossref","first-page":"7873","DOI":"10.1523\/JNEUROSCI.22-18-07873.2002","article-title":"Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy","volume":"22","author":"Bacskai","year":"2002","journal-title":"J Neurosci"},{"key":"2016042702422984000_139.5.1587.6","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1292-12.2012"},{"key":"2016042702422984000_139.5.1587.7","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0436286100"},{"key":"2016042702422984000_139.5.1587.8","doi-asserted-by":"publisher","DOI":"10.1038\/78682"},{"key":"2016042702422984000_139.5.1587.9","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20131660"},{"key":"2016042702422984000_139.5.1587.10","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-010-0705-y"},{"key":"2016042702422984000_139.5.1587.11","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2011-110977"},{"key":"2016042702422984000_139.5.1587.12","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1697-05.2005"},{"key":"2016042702422984000_139.5.1587.13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0018296"},{"key":"2016042702422984000_139.5.1587.14","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3302440"},{"key":"2016042702422984000_139.5.1587.15","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu213"},{"key":"2016042702422984000_139.5.1587.16","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(01)00245-7"},{"key":"2016042702422984000_139.5.1587.17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.151261398"},{"key":"2016042702422984000_139.5.1587.18","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.10.029"},{"key":"2016042702422984000_139.5.1587.19","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1312889"},{"key":"2016042702422984000_139.5.1587.20","doi-asserted-by":"publisher","DOI":"10.1006\/exer.1996.0020"},{"key":"2016042702422984000_139.5.1587.21","doi-asserted-by":"publisher","DOI":"10.1021\/bm070228f"},{"key":"2016042702422984000_139.5.1587.22","doi-asserted-by":"crossref","first-page":"235","DOI":"10.3389\/fnins.2014.00235","article-title":"New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease","volume":"8","author":"Fuller","year":"2014","journal-title":"Front Neurosci"},{"key":"2016042702422984000_139.5.1587.23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2005.04.045"},{"key":"2016042702422984000_139.5.1587.24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2011.07575.x"},{"key":"2016042702422984000_139.5.1587.25","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2010.06683.x"},{"key":"2016042702422984000_139.5.1587.26","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2009.09.004"},{"key":"2016042702422984000_139.5.1587.27","doi-asserted-by":"publisher","DOI":"10.1126\/science.1072994"},{"key":"2016042702422984000_139.5.1587.28","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.10.026"},{"key":"2016042702422984000_139.5.1587.29","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.09.071"},{"key":"2016042702422984000_139.5.1587.30","doi-asserted-by":"publisher","DOI":"10.1172\/JCI25410"},{"key":"2016042702422984000_139.5.1587.31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0018268"},{"key":"2016042702422984000_139.5.1587.32","doi-asserted-by":"publisher","DOI":"10.1107\/S0909049509017920"},{"key":"2016042702422984000_139.5.1587.33","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2009.167"},{"key":"2016042702422984000_139.5.1587.34","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.10.061"},{"key":"2016042702422984000_139.5.1587.35","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1202-06.2006"},{"key":"2016042702422984000_139.5.1587.36","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2004.07.003"},{"key":"2016042702422984000_139.5.1587.37","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2011.1538"},{"key":"2016042702422984000_139.5.1587.38","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.03.029"},{"key":"2016042702422984000_139.5.1587.39","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4337-04.2005"},{"key":"2016042702422984000_139.5.1587.40","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M303164200"},{"key":"2016042702422984000_139.5.1587.41","doi-asserted-by":"publisher","DOI":"10.2174\/1567205011310030001"},{"key":"2016042702422984000_139.5.1587.42","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1304839"},{"key":"2016042702422984000_139.5.1587.43","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh1092"},{"key":"2016042702422984000_139.5.1587.44","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq056"},{"key":"2016042702422984000_139.5.1587.45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2008.09.020"},{"key":"2016042702422984000_139.5.1587.46","doi-asserted-by":"publisher","DOI":"10.1002\/gps.2828"},{"key":"2016042702422984000_139.5.1587.47","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70015-7"},{"key":"2016042702422984000_139.5.1587.48","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.003"},{"key":"2016042702422984000_139.5.1587.49","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-009-9157-5"},{"key":"2016042702422984000_139.5.1587.50","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2005.04.007"},{"key":"2016042702422984000_139.5.1587.51","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5077-10.2011"},{"key":"2016042702422984000_139.5.1587.52","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2008.170"},{"key":"2016042702422984000_139.5.1587.53","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2010.05.010"},{"key":"2016042702422984000_139.5.1587.54","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.166.12.7496"},{"key":"2016042702422984000_139.5.1587.55","doi-asserted-by":"publisher","DOI":"10.1364\/OPEX.13.006296"},{"key":"2016042702422984000_139.5.1587.56","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0695-06.2006"},{"key":"2016042702422984000_139.5.1587.57","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1339-09.2009"},{"key":"2016042702422984000_139.5.1587.58","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.277"},{"key":"2016042702422984000_139.5.1587.59","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1090-04.2004"},{"key":"2016042702422984000_139.5.1587.60","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-1-24"},{"key":"2016042702422984000_139.5.1587.61","doi-asserted-by":"publisher","DOI":"10.1038\/270725a0"},{"key":"2016042702422984000_139.5.1587.62","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1018987108"},{"key":"2016042702422984000_139.5.1587.63","first-page":"107","article-title":"Production of lentiviral vectors","volume":"261","author":"Zufferey","year":"2002","journal-title":"Curr Top Microbiol Immunol"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/139\/5\/1587\/17349218\/aww036.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T06:18:15Z","timestamp":1567664295000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/aww036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,8]]},"references-count":63,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2016,4,26]]},"published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1093\/brain\/aww036"],"URL":"https:\/\/doi.org\/10.1093\/brain\/aww036","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.726204542.793518951","asserted-by":"object"}]},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,8]]}}}