{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T03:57:14Z","timestamp":1793246234692,"version":"4.5.0"},"reference-count":66,"publisher":"Oxford University Press (OUP)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1093\/brain\/aww158","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T22:09:23Z","timestamp":1467238163000},"page":"2122-2130","source":"Crossref","is-referenced-by-count":395,"title":["Zika virus-associated neurological disorders: a review"],"prefix":"10.1093","volume":"139","author":[{"given":"Abelardo Q. C.","family":"Araujo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus Tulius T.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra P. Q. C.","family":"Araujo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,6,29]]},"reference":[{"key":"2016123003351144000_139.8.2122.1","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1128\/IAI.12.5.1173-1183.1975","article-title":"Intrauterine infection of mice with St. Louis encephalitis virus: immunological, physiological, neurological, and behavioral effects on progeny.","volume":"12:","author":"Andersen","year":"1975;","journal-title":"Infect Immun"},{"key":"2016123003351144000_139.8.2122.2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-13-254"},{"key":"2016123003351144000_139.8.2122.3","unstructured":"Bahia SdS. Panorama na Bahia. Dengue, Chikungunya e Zika. 6 de Julho de 2015. 2015. <http:\/\/www.saude.ba.gov.br\/novoportal\/index.php?option=com_content&view=article&id=9497:panorama-na-bahia&catid=98:dengue-zika-chikungunya-e-sgb> (19 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00545-6"},{"key":"2016123003351144000_139.8.2122.5","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit227"},{"key":"2016123003351144000_139.8.2122.6","doi-asserted-by":"publisher","DOI":"10.1007\/BF01249709"},{"key":"2016123003351144000_139.8.2122.7","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2014.19.13.20751"},{"key":"2016123003351144000_139.8.2122.8","first-page":"1","article-title":"Situa\u00e7\u00e3o epidemiol\u00f3gica de ocorr\u00eancia de microcefalias no Brasil, 2015.","volume":"46:","author":"Brasil MdSd.","year":"2015;","journal-title":"Boletim Epidemil\u00f3gico"},{"key":"2016123003351144000_139.8.2122.9","unstructured":"Brasil MdSd. Informe Epidemiol\u00f3gico n. Semana Epidemiol\u00f3gica (SE) 16\/2016 (17\/04 a 23\/04\/2016). Monitoramento de casos de microcefalia no Brasil. 2016a. http:\/\/combateaedes.saude.gov.br\/images\/sala-de-situacao\/informe_microcefalia_epidemiologico23.pdf (21 May 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.10","first-page":"1","article-title":"Monitoramento dos casos de microcefalia no Brasil at\u00e9 a semana Epidemiol\u00f3gica 51\/2015.","volume":"47:","author":"Brasil MdSd.","year":"2016;","journal-title":"Boletim Epidemiol\u00f3gico"},{"key":"2016123003351144000_139.8.2122.11","doi-asserted-by":"crossref","unstructured":"Brasil P, Pereira JP Jr, Raja Gabaglia C, Damasceno L, Wakimoto M, Ribeiro Nogueira RM, . Zika virus infection in pregnant women in Rio de Janeiro - Preliminary Report. N Engl J Med 2016c. 10.1056\/NEJMoa1602412","DOI":"10.1056\/NEJMoa1602412"},{"key":"2016123003351144000_139.8.2122.12","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(16)00095-5"},{"key":"2016123003351144000_139.8.2122.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00562-6"},{"key":"2016123003351144000_139.8.2122.14","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70150-9"},{"key":"2016123003351144000_139.8.2122.15","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1602964"},{"key":"2016123003351144000_139.8.2122.16","unstructured":"CDC. Areas with Zika. 2016a. <http:\/\/www.cdc.gov\/zika\/geo\/index.html> (13 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.17","unstructured":"CDC. Emergency Preparedness and Response. Zika virus. 2016b. <http:\/\/www.cdc.gov\/zika\/index.html> (20 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.18","first-page":"157","article-title":"Dengue: neuropathological findings in 5 fatal cases from Brazil.","volume":"9:","author":"Chimelli","year":"1990;","journal-title":"Clin Neuropathol"},{"key":"2016123003351144000_139.8.2122.19","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/nature18296","article-title":"The Brazilian Zika virus strain causes birth defects in experimental models.","volume":"534:","author":"Cugola","year":"2016;","journal-title":"Nature"},{"key":"2016123003351144000_139.8.2122.20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i1901"},{"key":"2016123003351144000_139.8.2122.21","doi-asserted-by":"crossref","unstructured":"de Paula Freitas B, de Oliveira Dias JR, Prazeres J, Sacramento GA, Ko AI, Maia M, . Ocular findings in infants with microcephaly associated with presumed Zika virus congenital infection in Salvador, Brazil. JAMA Ophthalmol 2016; 134(5):529\u2013535.10.1001\/jamaophthalmol.2016.0267","DOI":"10.1001\/jamaophthalmol.2016.0267"},{"key":"2016123003351144000_139.8.2122.22","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(52)90042-4"},{"key":"2016123003351144000_139.8.2122.23","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1601824"},{"key":"2016123003351144000_139.8.2122.24","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0805715"},{"key":"2016123003351144000_139.8.2122.25","unstructured":"E.C.D.C. Rapid risk assessment. Zika virus epidemic in the Americas: potential association with microcephaly and Guillain-Barr\u00e9 2015. http:\/\/ecdc.europa.eu\/en\/publications\/Publications\/zika-virus-americas-association-with-microcephaly-rapid-risk-assessment.pdf (22 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.26","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf5036"},{"key":"2016123003351144000_139.8.2122.27","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/brain\/awt285","article-title":"Diagnosis of Guillain-Barre syndrome and validation of Brighton criteria.","volume":"137 (Pt 1):","author":"Fokke","year":"2014;","journal-title":"Brain"},{"key":"2016123003351144000_139.8.2122.28","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf6116"},{"key":"2016123003351144000_139.8.2122.29","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67665-9"},{"key":"2016123003351144000_139.8.2122.30","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2014.04.008"},{"key":"2016123003351144000_139.8.2122.31","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2005.11.040"},{"key":"2016123003351144000_139.8.2122.32","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2016.06.014"},{"key":"2016123003351144000_139.8.2122.33","doi-asserted-by":"crossref","unstructured":"Lucchese G, Kanduc D . Zika virus and autoimmunity: from microcephaly to Guillain-Barre syndrome, and beyond. Autoimmun Rev 2016. Advance Access published on March 25, 2016, doi: 10.1016\/j.autrev.2016.03.020","DOI":"10.1016\/j.autrev.2016.03.020"},{"key":"2016123003351144000_139.8.2122.34","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(54)90006-1"},{"key":"2016123003351144000_139.8.2122.35","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6506e1"},{"key":"2016123003351144000_139.8.2122.36","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1099\/0022-1317-59-1-213","article-title":"Transplacental Japanese encephalitis virus (JEV) infection in mice during consecutive pregnancies.","volume":"59 (Pt 1):","author":"Mathur","year":"1982;","journal-title":"J Gen Virol"},{"key":"2016123003351144000_139.8.2122.37","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00644-9"},{"key":"2016123003351144000_139.8.2122.38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.05.008"},{"key":"2016123003351144000_139.8.2122.39","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2016.04.009"},{"key":"2016123003351144000_139.8.2122.40","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1600651"},{"key":"2016123003351144000_139.8.2122.41","doi-asserted-by":"crossref","unstructured":"Musso D, Nhan T, Robin E, Roche C, Bierlaire D, Zisou K, . Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014. Euro Surveill 2014; 19: pii=20761.","DOI":"10.2807\/1560-7917.ES2014.19.14.20761"},{"key":"2016123003351144000_139.8.2122.42","doi-asserted-by":"publisher","DOI":"10.3201\/eid2102.141363"},{"key":"2016123003351144000_139.8.2122.43","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2024"},{"key":"2016123003351144000_139.8.2122.44","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2015.20.48.30079"},{"key":"2016123003351144000_139.8.2122.45","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES2014.19.9.20720"},{"key":"2016123003351144000_139.8.2122.46","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15831"},{"key":"2016123003351144000_139.8.2122.47","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.04.032"},{"key":"2016123003351144000_139.8.2122.48","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3180616d4f"},{"key":"2016123003351144000_139.8.2122.49","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2016.04.002"},{"key":"2016123003351144000_139.8.2122.50","unstructured":"Sant\u00e9 Ddl. Surveillance de la dengue et du zika en Polyn\u00e9sie Fran\u00e7aise 2014. <http:\/\/www.hygiene-publique.gov.pf\/spip.php?article120> (22 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.51","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6503e2"},{"key":"2016123003351144000_139.8.2122.52","first-page":"675, 682","article-title":"Guillain-Barre syndrome occurring during dengue fever.","volume":"109:","author":"Sharma","year":"2011;","journal-title":"J Indian Med Assoc"},{"key":"2016123003351144000_139.8.2122.53","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02036-5"},{"key":"2016123003351144000_139.8.2122.54","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2016.02.016"},{"key":"2016123003351144000_139.8.2122.55","doi-asserted-by":"publisher","DOI":"10.5935\/0004-2749.20160002"},{"key":"2016123003351144000_139.8.2122.56","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652015000300017"},{"key":"2016123003351144000_139.8.2122.57","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.15-0170"},{"key":"2016123003351144000_139.8.2122.58","unstructured":"WHO Emergencies preparedness, response. Guillain-Barr\u00e9 syndrome \u2013 Brazil. 2016a. <http:\/\/www.who.int\/csr\/don\/8-february-2016-gbs-brazil\/en\/> (19 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.59","unstructured":"WHO Emergencies preparedness, response. Guillain-Barr\u00e9 syndrome \u2013 Colombia and Venezuela. 2016b. <http:\/\/www.who.int\/csr\/don\/12-february-2016-gbs-colombia-venezuela\/en\/> (19 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.60","unstructured":"WHO WHO statement on the first meeting of the International Health Regulations (2005) (IHR 2005) emergency committee on Zika virus and observed increase in neurological disorders and neonatal malformations. 2016c. <http:\/\/www.who.int\/mediacentre\/news\/statements\/2016\/1st-emergency-committee-zika\/en\/> (13 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.61","unstructured":"WHO. 2016d.. Zika situation report. Neurological syndrome and congenital abnormalities. <http:\/\/www.who.int\/mediacentre\/news\/statements\/2016\/emergency-committee-zika-microcephaly\/en\/> (13 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.62","unstructured":"WHO. 2016e.. Zika situation report. Zika and potential complications 2016. <http:\/\/www.who.int\/emergencies\/zika-virus\/situation-report\/12-february-2016\/en\/> (23 February 2016, date last accessed)."},{"key":"2016123003351144000_139.8.2122.63","doi-asserted-by":"publisher","DOI":"10.1586\/1744666X.2013.811119"},{"key":"2016123003351144000_139.8.2122.64","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000277267.07220.88"},{"key":"2016123003351144000_139.8.2122.65","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf272"},{"key":"2016123003351144000_139.8.2122.66","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2016.58"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/139\/8\/2122\/17944841\/aww158.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:10:42Z","timestamp":1600819842000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/aww158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,29]]},"references-count":66,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2016,7,25]]},"published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1093\/brain\/aww158"],"URL":"https:\/\/doi.org\/10.1093\/brain\/aww158","relation":{},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,29]]}}}