{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T16:25:57Z","timestamp":1790180757364,"version":"4.1.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Brain"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1093\/brain\/aww296","type":"journal-article","created":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T08:05:18Z","timestamp":1477987518000},"page":"387-398","source":"Crossref","is-referenced-by-count":79,"title":["An abnormal periventricular magnetization transfer ratio gradient occurs early in multiple sclerosis"],"prefix":"10.1093","volume":"140","author":[{"given":"J. William L.","family":"Brown","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Pardini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wallace J.","family":"Brownlee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kryshani","family":"Fernando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca S.","family":"Samson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferran","family":"Prados Carrasco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastien","family":"Ourselin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia A. M.","family":"Gandini Wheeler-Kingshott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Declan T.","family":"Chard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,1,2]]},"reference":[{"key":"2017013007501518000_140.2.387.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1987.tb00177.x"},{"key":"2017013007501518000_140.2.387.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(99)00225-8"},{"key":"2017013007501518000_140.2.387.3","doi-asserted-by":"publisher","DOI":"10.1007\/s002340050321"},{"key":"2017013007501518000_140.2.387.4","doi-asserted-by":"publisher","DOI":"10.1016\/0730-725X(96)00019-7"},{"key":"2017013007501518000_140.2.387.5","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.11.2059"},{"key":"2017013007501518000_140.2.387.6","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-11-142"},{"key":"2017013007501518000_140.2.387.7","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.25.4.315"},{"key":"2017013007501518000_140.2.387.8","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-308675"},{"key":"2017013007501518000_140.2.387.9","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.64.10.1416"},{"key":"2017013007501518000_140.2.387.10","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22214"},{"key":"2017013007501518000_140.2.387.11","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.5.871"},{"key":"2017013007501518000_140.2.387.12","doi-asserted-by":"publisher","DOI":"10.1097\/01.WCB.0000053472.41007.F9"},{"key":"2017013007501518000_140.2.387.13","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.182.2.1732968"},{"key":"2017013007501518000_140.2.387.14","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200003)47:3<391::AID-ANA20>3.0.CO;2-J"},{"key":"2017013007501518000_140.2.387.15","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh654"},{"key":"2017013007501518000_140.2.387.16","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm329"},{"key":"2017013007501518000_140.2.387.17","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.62.5.803"},{"key":"2017013007501518000_140.2.387.18","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2586(200006)11:6<586::AID-JMRI3>3.0.CO;2-V"},{"issue":"Pt 2","key":"2017013007501518000_140.2.387.19","first-page":"58","article-title":"Symmetric atlasing and model based segmentation: an application to the hippocampus in older adults","volume":"9","author":"Grabner","year":"2006","journal-title":"Med Image Comput Comput Assisted Interv"},{"key":"2017013007501518000_140.2.387.20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2009.02.379"},{"key":"2017013007501518000_140.2.387.21","doi-asserted-by":"publisher","DOI":"10.1191\/1352458502ms824xx"},{"key":"2017013007501518000_140.2.387.22","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1227-1"},{"key":"2017013007501518000_140.2.387.23","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e328346a43b"},{"key":"2017013007501518000_140.2.387.24","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv065"},{"key":"2017013007501518000_140.2.387.25","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22230"},{"key":"2017013007501518000_140.2.387.26","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-8119(03)00169-1"},{"key":"2017013007501518000_140.2.387.27","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(98)00171-2"},{"key":"2017013007501518000_140.2.387.28","doi-asserted-by":"publisher","DOI":"10.1117\/1.JMI.1.2.024003"},{"key":"2017013007501518000_140.2.387.29","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2009.09.002"},{"key":"2017013007501518000_140.2.387.30","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.23970"},{"key":"2017013007501518000_140.2.387.31","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410410314"},{"key":"2017013007501518000_140.2.387.32","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182a08ce8"},{"key":"2017013007501518000_140.2.387.33","doi-asserted-by":"publisher","DOI":"10.1016\/S0262-8856(00)00052-4"},{"key":"2017013007501518000_140.2.387.34","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22366"},{"key":"2017013007501518000_140.2.387.35","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410130302"},{"key":"2017013007501518000_140.2.387.36","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.neuroimage.2016.06.053","article-title":"A multi-time-point modality-agnostic patch-based method for lesion filling in multiple sclerosis","volume":"139","author":"Prados","year":"2016","journal-title":"Neuroimage"},{"key":"2017013007501518000_140.2.387.37","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-008-0776-z"},{"key":"2017013007501518000_140.2.387.38","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1177\/1352458514522537","article-title":"Investigation of outer cortical magnetisation transfer ratio abnormalities in multiple sclerosis clinical subgroups","volume":"20","author":"Samson","year":"2014","journal-title":"Mul Scler"},{"key":"2017013007501518000_140.2.387.39","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20984"},{"key":"2017013007501518000_140.2.387.40","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv105"},{"key":"2017013007501518000_140.2.387.41","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199801293380502"},{"key":"2017013007501518000_140.2.387.42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2008.12.036"},{"key":"2017013007501518000_140.2.387.43","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu139"},{"key":"2017013007501518000_140.2.387.44","first-page":"2005","article-title":"Normal-appearing white matter changes vary with distance to lesions in multiple sclerosis","volume":"27","author":"Vrenken","year":"2006","journal-title":"AJNR Am J Neuroradiol"}],"container-title":["Brain"],"original-title":[],"language":"en","deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T22:31:08Z","timestamp":1498343468000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article-lookup\/doi\/10.1093\/brain\/aww296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,2]]},"references-count":44,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2017,1,30]]},"published-print":{"date-parts":[[2017,2]]}},"alternative-id":["10.1093\/brain\/aww296"],"URL":"https:\/\/doi.org\/10.1093\/brain\/aww296","relation":{},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,2]]}}}