{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:08:41Z","timestamp":1792807721114,"version":"4.5.0"},"reference-count":59,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T00:00:00Z","timestamp":1550707200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institute of Health Research","doi-asserted-by":"crossref","award":["#286641"],"award-info":[{"award-number":["#286641"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Weston Foundation","award":["#N\/A"],"award-info":[{"award-number":["#N\/A"]}]},{"name":"Fonds de la Recherche en Sante Quebec","award":["#28915"],"award-info":[{"award-number":["#28915"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3,1]]},"DOI":"10.1093\/brain\/awz030","type":"journal-article","created":{"date-parts":[[2019,1,26]],"date-time":"2019-01-26T00:54:05Z","timestamp":1548464045000},"page":"744-759","source":"Crossref","is-referenced-by-count":1137,"title":["Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study"],"prefix":"10.1093","volume":"142","author":[{"given":"Ronald B","family":"Postuma","sequence":"first","affiliation":[{"name":"Department of Neurology, McGill University, Montreal General Hospital, Montreal, Canada"},{"name":"Centre d\u2019\u00c9tudes Avanc\u00e9es en M\u00e9decine du Sommeil, H\u00f4pital du Sacr\u00e9-C\u0153ur de Montr\u00e9al, Montr\u00e9al, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Iranzo","sequence":"additional","affiliation":[{"name":"Neurology Service, Hospital Clinic de Barcelona, IDIBAPS, CIBERNED, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Hu","sequence":"additional","affiliation":[{"name":"Oxford Parkinson\u2019s Disease Centre (OPDC) and Oxford University, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"H\u00f6gl","sequence":"additional","affiliation":[{"name":"Department of Neurology, Innsbruck Medical University, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley F","family":"Boeve","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Manni","sequence":"additional","affiliation":[{"name":"Unit of Sleep Medicine and Epilepsy, IRCCS, C.Mondino Foundation, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang H","family":"Oertel","sequence":"additional","affiliation":[{"name":"Department of Neurology, Philipps-Universit\u00e4t, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Arnulf","sequence":"additional","affiliation":[{"name":"Sleep disorders unit, Pitie-Salpetriere Hospital, IHU@ICM and Sorbonne University, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Ferini-Strambi","sequence":"additional","affiliation":[{"name":"Sleep Disorders Center, Department of Neurology, Scientific Institute Ospedale San Raffaele, Vita-Salute University, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Puligheddu","sequence":"additional","affiliation":[{"name":"Sleep Center, Department of Cardiovascular and Neurological Sciences, University of Cagliari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Antelmi","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy"},{"name":"IRCCS Institute of the Neurological Sciences, Ospedale Bellaria, ASL di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Cochen De Cock","sequence":"additional","affiliation":[{"name":"Sleep and Neurology Unit, Beau Soleil Clinic, Montpellier, France; EuroMov, University of Montpellier, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Arnaldi","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Dept. of Neuroscience (DINOGMI), University of Genoa, and Polyclinic San Martino Hospital, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brit","family":"Mollenhauer","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery (C.T.) University Medical Center, G\u00f6ttingen; Paracelsus-Elena-Klinik (B.M., C.T. F. S-D.), Kassel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandar","family":"Videnovic","sequence":"additional","affiliation":[{"name":"Movement Disorders Unit and Division of Sleep Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karel","family":"Sonka","sequence":"additional","affiliation":[{"name":"Department of Neurology and Centre of Clinical Neurosciences of the First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki-Young","family":"Jung","sequence":"additional","affiliation":[{"name":"Neuroscience Research Institute, Seoul National University College of Medicine, Department of Neurology, Seoul National University Hospital, Seoul, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieter","family":"Kunz","sequence":"additional","affiliation":[{"name":"Institute of Physiology Charit\u00e9-Universit\u00e4tsmedizin Berlin. Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Dauvilliers","sequence":"additional","affiliation":[{"name":"Sleep Unit, Department of Neurology, H\u00f4pital Gui de Chauliac, Montpellier, INSERM U1061, Montpellier, F-34093 Cedex 5 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Provini","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences, Bellaria Hospital, University of Bologna, Bologna, Italy"},{"name":"IRCCS Institute of Neurological Sciences of Bologna, Bellaria Hospital, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon J","family":"Lewis","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre University of Sydney, Camperdown, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitka","family":"Buskova","sequence":"additional","affiliation":[{"name":"National Institute of Mental Health, Klecany, Third Faculty of Medicine, Charles Unviersity, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milena","family":"Pavlova","sequence":"additional","affiliation":[{"name":"Department of Neurology, Brigham and Women\u2019s Hospital, Boston; Harvard Medical School, Boston, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Heidbreder","sequence":"additional","affiliation":[{"name":"Institute for Sleep Medicine and Neuromuscular Disorders, University Hospital Muenster, Muenster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques Y","family":"Montplaisir","sequence":"additional","affiliation":[{"name":"Centre d\u2019\u00c9tudes Avanc\u00e9es en M\u00e9decine du Sommeil, H\u00f4pital du Sacr\u00e9-C\u0153ur de Montr\u00e9al, Montr\u00e9al, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Santamaria","sequence":"additional","affiliation":[{"name":"Sleep and Neurology Unit, Beau Soleil Clinic, Montpellier, France; EuroMov, University of Montpellier, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas R","family":"Barber","sequence":"additional","affiliation":[{"name":"Oxford Parkinson\u2019s Disease Centre (OPDC) and Oxford University, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambra","family":"Stefani","sequence":"additional","affiliation":[{"name":"Department of Neurology, Innsbruck Medical University, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik K","family":"St.Louis","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Terzaghi","sequence":"additional","affiliation":[{"name":"Unit of Sleep Medicine and Epilepsy, IRCCS, C.Mondino Foundation, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Janzen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Philipps-Universit\u00e4t, Marburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smandra","family":"Leu-Semenescu","sequence":"additional","affiliation":[{"name":"Sleep disorders unit, Pitie-Salpetriere Hospital, IHU@ICM and Sorbonne University, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiseppe","family":"Plazzi","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy"},{"name":"IRCCS Institute of the Neurological Sciences, Ospedale Bellaria, ASL di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Nobili","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Dept. of Neuroscience (DINOGMI), University of Genoa, and Polyclinic San Martino Hospital, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friederike","family":"Sixel-Doering","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery (C.T.) University Medical Center, G\u00f6ttingen; Paracelsus-Elena-Klinik (B.M., C.T. F. S-D.), Kassel, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Dusek","sequence":"additional","affiliation":[{"name":"Department of Neurology and Centre of Clinical Neurosciences of the First Faculty of Medicine, Charles University and General University Hospital in Prague, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederik","family":"Bes","sequence":"additional","affiliation":[{"name":"Institute of Physiology Charit\u00e9-Universit\u00e4tsmedizin Berlin. Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Cortelli","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences, Bellaria Hospital, University of Bologna, Bologna, Italy"},{"name":"IRCCS Institute of Neurological Sciences of Bologna, Bellaria Hospital, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaylena","family":"Ehgoetz Martens","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre University of Sydney, Camperdown, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Francois","family":"Gagnon","sequence":"additional","affiliation":[{"name":"Department of Psychology, Universit\u00e9 du Qu\u00e9bec \u00e0 Montr\u00e9al, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carles","family":"Gaig","sequence":"additional","affiliation":[{"name":"Neurology Service, Hospital Clinic de Barcelona, IDIBAPS, CIBERNED, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Zucconi","sequence":"additional","affiliation":[{"name":"Sleep Disorders Center, Department of Neurology, Scientific Institute Ospedale San Raffaele, Vita-Salute University, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Trenkwalder","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Dept. of Neuroscience (DINOGMI), University of Genoa, and Polyclinic San Martino Hospital, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziv","family":"Gan-Or","sequence":"additional","affiliation":[{"name":"Department of Human Genetics, McGill University, Montreal, Canada"},{"name":"Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Lo","sequence":"additional","affiliation":[{"name":"Oxford Parkinson\u2019s Disease Centre (OPDC) and Oxford University, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Rolinski","sequence":"additional","affiliation":[{"name":"Oxford Parkinson\u2019s Disease Centre (OPDC) and Oxford University, Oxford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Mahlknecht","sequence":"additional","affiliation":[{"name":"Department of Neurology, Innsbruck Medical University, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evi","family":"Holzknecht","sequence":"additional","affiliation":[{"name":"Department of Neurology, Innsbruck Medical University, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel R","family":"Boeve","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke N","family":"Teigen","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianpaolo","family":"Toscano","sequence":"additional","affiliation":[{"name":"Unit of Sleep Medicine and Epilepsy, IRCCS, C.Mondino Foundation, Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geert","family":"Mayer","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hephata Klinik, Schwalmstadt-Treysa, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Morbelli","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Department of Health Sciences (DISSAL), University of Genoa and Polyclinic San Martino Hospital, Genoa, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Dawson","sequence":"additional","affiliation":[{"name":"Department of Neurology, McGill University, Montreal General Hospital, Montreal, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelie","family":"Pelletier","sequence":"additional","affiliation":[{"name":"Department of Neurology, McGill University, Montreal General Hospital, Montreal, Canada"},{"name":"Centre d\u2019\u00c9tudes Avanc\u00e9es en M\u00e9decine du Sommeil, H\u00f4pital du Sacr\u00e9-C\u0153ur de Montr\u00e9al, Montr\u00e9al, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,2,20]]},"reference":[{"key":"key\n\t\t\t\t2019022703310298700_awz030-B1","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1002\/mds.26605","article-title":"Neuropathological basis of nonmotor manifestations of Parkinson\u2019s disease","volume":"31","author":"Adler","year":"2016","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B2","volume-title":"The international classification of sleep disorders: diagnostic and coding manual","year":"2007"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B3","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.5665\/sleep.5040","article-title":"Sleepiness in idiopathic REM sleep behavior disorder and Parkinson disease","volume":"38","author":"Arnulf","year":"2015","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B4","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsx071","article-title":"Prodromal Parkinsonism and neurodegenerative risk stratification in REM sleep behaviour disorder","author":"Barber","year":"2017","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S1389-9457(00)00065-4","article-title":"Validation of the Insomnia Severity Index as an outcome measure for insomnia research","volume":"2","author":"Bastien","year":"2001","journal-title":"Sleep Med"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B6","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1037\/0022-006X.56.6.893","article-title":"An inventory for measuring clinical anxiety: psychometric properties","volume":"56","author":"Beck","year":"1988","journal-title":"J Consult Clin Psychol"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B7","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","article-title":"An inventory for measuring depression","volume":"4","author":"Beck","year":"1961","journal-title":"Arch Gen Psychiatry"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B8","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1002\/mds.26431","article-title":"MDS research criteria for prodromal Parkinson\u2019s disease","volume":"30","author":"Berg","year":"2015","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B9","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1002\/mds.25272","article-title":"Color discrimination deficits in Parkinson\u2019s disease are related to cognitive impairment and white-matter alterations","volume":"27","author":"Bertrand","year":"2012","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B10","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1002\/mds.20844","article-title":"International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson\u2019s disease: the NMSQuest study","volume":"21","author":"Chaudhuri","year":"2006","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B11","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.nicl.2013.02.006","article-title":"Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer\u2019s disease","volume":"2","author":"Chetelat","year":"2013","journal-title":"Neuroimage Clin"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B12","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1212\/WNL.44.12.2308","article-title":"The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia","volume":"44","author":"Cummings","year":"1994","journal-title":"Neurology"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B13","doi-asserted-by":"crossref","first-page":"217","DOI":"10.3109\/09638289509166638","article-title":"The Purdue Pegboard Test: normative data for people aged 60 and over","volume":"17","author":"Desrosiers","year":"1995","journal-title":"Disabil Rehabil"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B14","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0031-9384(84)90269-5","article-title":"Development of the University of Pennsylvania Smell Identification Test: a standardized microencapsulated test of olfactory function","volume":"32","author":"Doty","year":"1984","journal-title":"Physiol Behav"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B15","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1002\/mds.21844","article-title":"Diagnostic procedures for Parkinson\u2019s disease dementia: recommendations from the movement disorder society task force","volume":"22","author":"Dubois","year":"2007","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B16","first-page":"153","article-title":"The Unified Parkinson\u2019s Disease Rating Scale","volume-title":"Recent developments in Parkinson\u2019s disease","author":"Fahn","year":"1987"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B17","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1364\/JOSA.33.000568","article-title":"The Farnsworth 100-hue test and dichotomous tests for color vision","volume":"33","author":"Farnsworth","year":"1943","journal-title":"J Opt Soc Am"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B18","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1001\/jamaneurol.2015.0703","article-title":"New clinical subtypes of Parkinson disease and their longitudinal progression: a prospective cohort comparison with other phenotypes","volume":"72","author":"Fereshtehnejad","year":"2015","journal-title":"JAMA Neurol"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B19","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state\u201d. A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B20","doi-asserted-by":"crossref","first-page":"835","DOI":"10.5665\/sleep.1886","article-title":"Normative EMG values during REM sleep for the diagnosis of REM sleep behavior disorder","volume":"35","author":"Frauscher","year":"2012","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B21","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1207\/s15327906mbr1003_6","article-title":"Validation of the state-trait distinction in anxiety research","volume":"10","author":"Gaudry","year":"1975","journal-title":"Multivariate Behav Res"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B22","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1002\/mds.22340","article-title":"Movement Disorder Society-sponsored revision of the Unified Parkinson\u2019s Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results","volume":"23","author":"Goetz","year":"2008","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B23","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1097\/WCO.0000000000000112","article-title":"Premotor and nonmotor features of Parkinson\u2019s disease","volume":"27","author":"Goldman","year":"2014","journal-title":"Curr Opin Neurol"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B24","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsx197","article-title":"Prevalence and determinants of REM sleep behavior disorder in the general population","author":"Haba-Rubio","year":"2018","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B25","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1111\/j.1572-0241.2004.04114.x","article-title":"Epidemiology of constipation in North America: a systematic review","volume":"99","author":"Higgins","year":"2004","journal-title":"Am J Gastroenterol"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B26","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/nrneurol.2017.157","article-title":"Idiopathic REM sleep behaviour disorder and neurodegeneration\u2014an update","volume":"14","author":"Hogl","year":"2018","journal-title":"Nat Rev Neurol"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B27","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/chemse\/22.1.39","article-title":"\u2018Sniffin\u2019 Sticks\u2019: olfactory performance assessed by the combined testing of odour identification, odor discrimination and olfactory threshold","volume":"22","author":"Hummel","year":"1997","journal-title":"Chem Senses"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B28","doi-asserted-by":"crossref","first-page":"e89741","DOI":"10.1371\/journal.pone.0089741","article-title":"Neurodegenerative disorder risk in idiopathic REM sleep behavior disorder: study in 174 patients","volume":"9","author":"Iranzo","year":"2014","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B29","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1001\/jamaneurol.2017.0985","article-title":"Conversion to Parkinson\u2019s disease in the PARS Prodromal Cohort","volume":"74","author":"Jennings","year":"2017","journal-title":"JAMA Neurol"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B30","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A new method for measuring daytime sleepiness: the Epworth sleepiness scale","volume":"14","author":"Johns","year":"1991","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B31","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.5665\/sleep.2874","article-title":"REM sleep behavior disorder in the Korean elderly population: prevalence and clinical characteristics","volume":"36","author":"Kang","year":"2013","journal-title":"Sleep"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B32","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1159\/000444021","article-title":"Age, gender, comorbidity, and the MDS-UPDRS: results from a population-based study","volume":"46","author":"Keezer","year":"2016","journal-title":"Neuroepidemiology"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B33","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: validity of a brief depression severity measure","volume":"16","author":"Kroenke","year":"2001","journal-title":"J Gen Intern Med"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B34","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1212\/WNL.0000000000003838","article-title":"Predictive markers for early conversion of IRBD to neurodegenerative synucleinopathy diseases","volume":"88","author":"Li","year":"2017","journal-title":"Neurology"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B35","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1212\/WNL.0000000000001265","article-title":"Olfactory dysfunction predicts early transition to a Lewy body disease in idiopathic RBD","volume":"84","author":"Mahlknecht","year":"2015","journal-title":"Neurology"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B36","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1212\/WNL.0000000000004058","article-title":"Diagnosis and management of dementia with Lewy bodies: fourth consensus report of the dementia with Lewy bodies Consortium","volume":"89","author":"McKeith","year":"2017","journal-title":"Neurology"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B37","doi-asserted-by":"crossref","first-page":"2044","DOI":"10.1002\/mds.23257","article-title":"Polysomnographic diagnosis of idiopathic REM sleep behavior disorder","volume":"25","author":"Montplaisir","year":"2010","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B38","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1111\/j.1532-5415.2005.53221.x","article-title":"The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment","volume":"53","author":"Nasreddine","year":"2005","journal-title":"J Am Geriatr Soc"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B39","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/1531-8257(200009)15:5<843::AID-MDS1013>3.0.CO;2-2","article-title":"Determinants of tapping speed in normal control subjects and subjects with Parkinson\u2019s disease: differing effects of brief and continued practice","volume":"15","author":"Nutt","year":"2000","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B40","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1532-5415.1991.tb01616.x","article-title":"The timed \u201cUp & Go\u201d: a test of basic functional mobility for frail elderly persons","volume":"39","author":"Podsiadlo","year":"1991","journal-title":"J Am Geriatr Soc"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B41","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1002\/mds.26347","article-title":"REM sleep behavior disorder and neuropathology in Parkinson\u2019s disease","volume":"30","author":"Postuma","year":"2015","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B42","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1002\/mds.26424","article-title":"MDS clinical diagnostic criteria for Parkinson\u2019s disease","volume":"30","author":"Postuma","year":"2015","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B43","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1212\/WNL.0000000000001364","article-title":"Parkinson risk in idiopathic REM sleep behavior disorder: preparing for neuroprotective trials","volume":"84","author":"Postuma","year":"2015","journal-title":"Neurology"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B44","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1002\/ana.22282","article-title":"Olfaction and color vision identify impending neurodegeneration in REM behavior disorder","volume":"69","author":"Postuma","year":"2011","journal-title":"Ann Neurol"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B45","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1212\/01.wnl.0000340980.19702.6e","article-title":"Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder","volume":"72","author":"Postuma","year":"2009","journal-title":"Neurology"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B46","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1002\/ana.24385","article-title":"Risk factors for neurodegeneration in idiopathic rapid eye movement sleep behavior disorder: a multicenter study","volume":"77","author":"Postuma","year":"2015","journal-title":"Ann Neurol"},{"issue":"Pt 6","key":"key\n\t\t\t\t2019022703310298700_awz030-B47","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1093\/brain\/aws093","article-title":"How does parkinsonism start? Prodromal parkinsonism motor changes in idiopathic REM sleep behaviour disorder","volume":"135","author":"Postuma","year":"2012","journal-title":"Brain"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B48","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.sleep.2017.07.021","article-title":"Idiopathic REM sleep behavior disorder in the elderly Spanish community: a primary care center study with a two-stage design using video-polysomnography","volume":"40","author":"Pujol","year":"2017","journal-title":"Sleep Med"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B49","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.sleep.2012.10.009","article-title":"Delayed emergence of a parkinsonian disorder or dementia in 81% of older men initially diagnosed with idiopathic rapid eye movement sleep behavior disorder: a 16-year update on a previously reported series","volume":"14","author":"Schenck","year":"2013","journal-title":"Sleep Med"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B50","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.sleep.2013.02.016","article-title":"Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy\u2014a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group","volume":"14","author":"Schenck","year":"2013","journal-title":"Sleep Med"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B51","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1192\/bjp.128.2.156","article-title":"The Leeds scales for the self-assessment of anxiety and depression","volume":"128","author":"Snaith","year":"1976","journal-title":"Br J Psychiatry"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B52","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0022-3999(00)00095-7","article-title":"Athens Insomnia Scale: validation of an instrument based on ICD-10 criteria","volume":"48","author":"Soldatos","year":"2000","journal-title":"J Psychosom Res"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B53","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: the GAD-7","volume":"166","author":"Spitzer","year":"2006","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B54","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/s41467-017-02761-0","article-title":"Ventromedial medulla inhibitory neuron inactivation induces REM sleep without atonia and REM sleep behavior disorder","volume":"9","author":"Valencia Garcia","year":"2018","journal-title":"Nat Commun"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B55","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1002\/mds.20153","article-title":"Assessment of autonomic dysfunction in Parkinson\u2019s disease: the SCOPA-AUT","volume":"19","author":"Visser","year":"2004","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B56","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1002\/mds.20255","article-title":"Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS)","volume":"19","author":"Wenning","year":"2004","journal-title":"Mov Disord"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B57","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1136\/jnnp-2011-301232","article-title":"Prospective outcome of rapid eye movement sleep behaviour disorder: psychiatric disorders as a potential early marker of Parkinson\u2019s disease","volume":"83","author":"Wing","year":"2012","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B58","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0022-3956(82)90033-4","article-title":"Development and validation of a geriatric depression screening scale: a preliminary report","volume":"17","author":"Yesavage","year":"1982","journal-title":"Journal of psychiatric research"},{"key":"key\n\t\t\t\t2019022703310298700_awz030-B59","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr Scand"}],"container-title":["Brain"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/brain\/article-pdf\/142\/3\/744\/27986652\/awz030.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T03:34:54Z","timestamp":1551238494000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/brain\/article\/142\/3\/744\/5353011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,20]]},"references-count":59,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,2,20]]},"published-print":{"date-parts":[[2019,3,1]]}},"URL":"https:\/\/doi.org\/10.1093\/brain\/awz030","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.735142222.793562064","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.735142222.793559394","asserted-by":"object"}]},"ISSN":["0006-8950","1460-2156"],"issn-type":[{"value":"0006-8950","type":"print"},{"value":"1460-2156","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,3]]},"published":{"date-parts":[[2019,2,20]]}}}