{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T20:35:41Z","timestamp":1772138141899,"version":"3.50.1"},"reference-count":83,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T00:00:00Z","timestamp":1621209600000},"content-version":"vor","delay-in-days":136,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Australian National Health and Medical Research Council","award":["GNT1091310"],"award-info":[{"award-number":["GNT1091310"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Deficits in attention underpin many of the cognitive and neuropsychiatric features of Lewy body dementia. These attention-related symptoms remain difficult to treat and there are many gaps in our understanding of their neurobiology. An improved understanding of attention-related impairments can be achieved via mathematical modelling approaches, which identify cognitive parameters to provide an intermediate level between observed behavioural data and its underlying neural correlate. Here, we apply this approach to identify the role of impaired sensory evidence accumulation in the attention deficits that characterize Lewy body dementia. In 31 people with Lewy body dementia (including 13 Parkinson\u2019s disease dementia and 18 dementia with Lewy bodies cases), 16 people with Alzheimer\u2019s disease, and 23 healthy controls, we administered an attention task whilst they underwent functional 3\u2009T MRI. Using hierarchical Bayesian estimation of a drift-diffusion model, we decomposed task performance into drift rate and decision boundary parameters. We tested the hypothesis that the drift rate\u2014a measure of the quality of sensory evidence accumulation\u2014is specifically impaired in Lewy body dementia, compared to Alzheimer\u2019s disease. We further explored whether trial-by-trial variations in the drift rate related to activity within the default and dorsal attention networks, to determine whether altered activity in these networks was associated with slowed drift rates in Lewy body dementia. Our results revealed slower drift rates in the Lewy body dementia compared to the Alzheimer\u2019s disease group, whereas the patient groups were equivalent for their decision boundaries. The patient groups were reduced relative to controls for both parameters. This highlights sensory evidence accumulation deficits as a key feature that distinguishes attention impairments in Lewy body dementia, consistent with impaired ability to efficiently process information from the environment to guide behaviour. We also found that the drift rate was strongly related to activity in the dorsal attention network across all three groups, whereas the Lewy body dementia group showed a divergent relationship relative to the Alzheimer\u2019s disease and control groups for the default network, consistent with altered default network modulation being associated with impaired evidence accumulation. Together, our findings reveal impaired sensory evidence accumulation as a specific marker of attention problems in Lewy body dementia, which may relate to large-scale network abnormalities. By identifying impairments in a specific sub-process of attention, these findings will inform future exploratory and intervention studies that aim to understand and treat attention-related symptoms that are a key feature of Lewy body dementia.<\/jats:p>","DOI":"10.1093\/braincomms\/fcab089","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T13:04:14Z","timestamp":1619096654000},"source":"Crossref","is-referenced-by-count":9,"title":["Impaired sensory evidence accumulation and network function in Lewy body dementia"],"prefix":"10.1093","volume":"3","author":[{"given":"Claire","family":"O\u2019Callaghan","sequence":"first","affiliation":[{"name":"Brain and Mind Centre and School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney 2050, Australia"},{"name":"Department of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Firbank","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Tomassini","sequence":"additional","affiliation":[{"name":"MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Schumacher","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John T","family":"O\u2019Brien","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John-Paul","family":"Taylor","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,8,2]]},"reference":[{"issue":"11","key":"2021121215281890000_fcab089-B1","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1212\/01.WNL.0000036908.39696.FD","article-title":"Fluctuations in attention: PD dementia vs DLB with parkinsonism","volume":"59","author":"Ballard","year":"2002","journal-title":"Neurology"},{"issue":"2","key":"2021121215281890000_fcab089-B2","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1097\/01.JGP.0000192480.89813.80","article-title":"Characteristics of visual hallucinations in Parkinson disease dementia and dementia with lewy bodies","volume":"14","author":"Mosimann","year":"2006","journal-title":"Am J Geriatr Psychiatry"},{"issue":"12","key":"2021121215281890000_fcab089-B3","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1002\/mds.21507","article-title":"Clinical diagnostic criteria for dementia associated with Parkinson\u2019s disease","volume":"22","author":"Emre","year":"2007","journal-title":"Mov Disord"},{"issue":"1","key":"2021121215281890000_fcab089-B4","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1212\/WNL.0000000000004058","article-title":"Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium","volume":"89","author":"McKeith","year":"2017","journal-title":"Neurology"},{"issue":"7","key":"2021121215281890000_fcab089-B5","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.3758\/s13414-019-01846-w","article-title":"No one knows what attention is","volume":"81","author":"Hommel","year":"2019","journal-title":"Atten Percept Psychophys"},{"issue":"4","key":"2021121215281890000_fcab089-B6","doi-asserted-by":"crossref","first-page":"ENEURO.0069-20.2020","DOI":"10.1523\/ENEURO.0069-20.2020","article-title":"The brain\u2013cognitive behavior problem: A retrospective","volume":"7","author":"Buzs\u00e1ki","year":"2020","journal-title":"eNeuro"},{"issue":"1","key":"2021121215281890000_fcab089-B7","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1146\/annurev-psych-122414-033645","article-title":"Sequential sampling models in cognitive neuroscience: Advantages, applications, and extensions","volume":"67","author":"Forstmann","year":"2016","journal-title":"Annu Rev Psychol"},{"key":"2021121215281890000_fcab089-B8","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.neuroscience.2014.07.031","article-title":"Perceptual decision neurosciences \u2013 A model-based review","volume":"277","author":"Mulder","year":"2014","journal-title":"Neuroscience"},{"issue":"1","key":"2021121215281890000_fcab089-B9","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/brain\/awv331","article-title":"Different decision deficits impair response inhibition in progressive supranuclear palsy and Parkinson\u2019s disease","volume":"139","author":"Zhang","year":"2016","journal-title":"Brain"},{"issue":"8","key":"2021121215281890000_fcab089-B10","first-page":"680","article-title":"Visual hallucinations are characterized by impaired sensory evidence accumulation: Insights from hierarchical drift diffusion modeling in Parkinson\u2019s disease","volume":"2","author":"O\u2019Callaghan","year":"2017","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"issue":"8","key":"2021121215281890000_fcab089-B11","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/j.cub.2018.02.057","article-title":"Mechanisms underlying decision-making as revealed by deep-brain stimulation in patients with Parkinson\u2019s disease","volume":"28","author":"Herz","year":"2018","journal-title":"Curr Biol"},{"key":"2021121215281890000_fcab089-B12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.neuropsychologia.2019.02.003","article-title":"Learning from the past and expecting the future in Parkinsonism: Dopaminergic influence on predictions about the timing of future events","volume":"127","author":"Tomassini","year":"2019","journal-title":"Neuropsychologia"},{"key":"2021121215281890000_fcab089-B13","doi-asserted-by":"crossref","DOI":"10.1093\/brain\/awab142","article-title":"Locus coeruleus integrity and the effect of atomoxetine on response inhibition in Parkinson\u2019s disease","author":"O\u2019Callaghan","year":"2021","journal-title":"Brain"},{"issue":"1","key":"2021121215281890000_fcab089-B14","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev.neuro.29.051605.113038","article-title":"The neural basis of decision making","volume":"30","author":"Gold","year":"2007","journal-title":"Annu Rev Neurosci"},{"issue":"4","key":"2021121215281890000_fcab089-B15","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1162\/neco.2008.12-06-420","article-title":"The diffusion decision model: Theory and data for two-choice decision tasks","volume":"20","author":"Ratcliff","year":"2008","journal-title":"Neural Comput"},{"issue":"6","key":"2021121215281890000_fcab089-B16","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1027\/1618-3169\/a000218","article-title":"Diffusion models in experimental psychology: A practical introduction","volume":"60","author":"Voss","year":"2013","journal-title":"Exp Psychol"},{"key":"2021121215281890000_fcab089-B17","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3389\/fnhum.2010.00215","article-title":"Attention, uncertainty, and free-energy","volume":"4","author":"Feldman","year":"2010","journal-title":"Front Hum Neurosci"},{"issue":"5","key":"2021121215281890000_fcab089-B18","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0010-9452(08)70489-1","article-title":"A review of cognitive impairments in dementia with lewy bodies relative to Alzheimer\u2019s disease and Parkinson\u2019s disease with dementia","volume":"43","author":"Metzler-Baddeley","year":"2007","journal-title":"Cortex"},{"issue":"11","key":"2021121215281890000_fcab089-B19","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1093\/brain\/aww175","article-title":"Visual dysfunction in Parkinson\u2019s disease","volume":"139","author":"Weil","year":"2016","journal-title":"Brain"},{"key":"2021121215281890000_fcab089-B20","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.pneurobio.2014.01.004","article-title":"Tricks of the mind: Visual hallucinations as disorders of attention","volume":"116","author":"Shine","year":"2014","journal-title":"Prog Neurobiol"},{"issue":"6","key":"2021121215281890000_fcab089-B21","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1093\/brain\/awv104","article-title":"Parkinson\u2019s disease dementia: A neural networks perspective","volume":"138","author":"Gratwicke","year":"2015","journal-title":"Brain"},{"issue":"11","key":"2021121215281890000_fcab089-B22","doi-asserted-by":"crossref","first-page":"3338","DOI":"10.1093\/brain\/awz235","article-title":"Fluctuating cognition in the Lewy body dementias","volume":"142","author":"O\u2019Dowd","year":"2019","journal-title":"Brain"},{"issue":"3","key":"2021121215281890000_fcab089-B23","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrn755","article-title":"Control of goal-directed and stimulus-driven attention in the brain","volume":"3","author":"Corbetta","year":"2002","journal-title":"Nat Rev Neurosci"},{"issue":"C","key":"2021121215281890000_fcab089-B24","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.neuroimage.2016.12.073","article-title":"Interactions between the default network and dorsal attention network vary across default subsystems, time, and cognitive states","volume":"147","author":"Dixon","year":"2017","journal-title":"NeuroImage"},{"issue":"10","key":"2021121215281890000_fcab089-B25","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1038\/s41583-019-0212-7","article-title":"The brain\u2019s default network: Updated anatomy, physiology and evolving insights","volume":"20","author":"Buckner","year":"2019","journal-title":"Nat Rev Neurosci"},{"issue":"7","key":"2021121215281890000_fcab089-B26","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1093\/brain\/awl102","article-title":"Differences between Alzheimer\u2019s disease and dementia with Lewy bodies: An fMRI study of task-related brain activity","volume":"129","author":"Sauer","year":"2006","journal-title":"Brain"},{"issue":"1","key":"2021121215281890000_fcab089-B27","first-page":"1","article-title":"Abnormal connectivity between the default mode and the visual system underlies the manifestation of visual hallucinations in Parkinson\u2019s disease: A task-based fMRI study. npj Parkinson\u2019s.","volume":"1","author":"Shine","year":"2015","journal-title":"Disease"},{"issue":"3","key":"2021121215281890000_fcab089-B28","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1002\/hbm.23100","article-title":"Neural correlates of attention-executive dysfunction in lewy body dementia and Alzheimer\u2019s disease","volume":"37","author":"Firbank","year":"2016","journal-title":"Hum Brain Mapp"},{"issue":"2","key":"2021121215281890000_fcab089-B29","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1002\/hbm.23866","article-title":"Long reaction times are associated with delayed brain activity in lewy body dementia","volume":"39","author":"Firbank","year":"2018","journal-title":"Hum Brain Mapp"},{"key":"2021121215281890000_fcab089-B30","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.cortex.2017.02.016","article-title":"Divergent functional connectivity during attentional processing in Lewy body dementia and Alzheimer\u2019s disease","volume":"92","author":"Kobeleva","year":"2017","journal-title":"Cortex"},{"issue":"8","key":"2021121215281890000_fcab089-B31","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1002\/mds.27781","article-title":"Hallucinations, somatic-functional disorders of PD-DLB as expressions of thalamic dysfunction","volume":"34","author":"Onofrj","year":"2019","journal-title":"Mov Disord"},{"key":"2021121215281890000_fcab089-B32","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.cortex.2019.12.023","article-title":"Mind-wandering in Parkinson\u2019s disease hallucinations reflects primary visual and default network coupling","volume":"125","author":"Walpola","year":"2020","journal-title":"Cortex"},{"key":"2021121215281890000_fcab089-B33","doi-asserted-by":"crossref","first-page":"101812","DOI":"10.1016\/j.nicl.2019.101812","article-title":"Dynamic functional connectivity changes in dementia with Lewy bodies and Alzheimer\u2019s disease","volume":"22","author":"Schumacher","year":"2019","journal-title":"Neuroimage Clin"},{"issue":"6","key":"2021121215281890000_fcab089-B34","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1093\/brain\/awz069","article-title":"Dysfunctional brain dynamics and their origin in Lewy body dementia","volume":"142","author":"Schumacher","year":"2019","journal-title":"Brain"},{"issue":"5417","key":"2021121215281890000_fcab089-B35","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1126\/science.284.5417.1158","article-title":"Separate signals for target selection and movement specification in the superior colliculus","volume":"284","author":"Horwitz","year":"1999","journal-title":"Science"},{"issue":"4","key":"2021121215281890000_fcab089-B36","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1152\/jn.2001.86.4.1916","article-title":"Neural basis of a perceptual decision in the parietal cortex (Area LIP) of the rhesus monkey","volume":"86","author":"Shadlen","year":"2001","journal-title":"J Neurophysiol"},{"issue":"21","key":"2021121215281890000_fcab089-B37","doi-asserted-by":"crossref","first-page":"9475","DOI":"10.1523\/JNEUROSCI.22-21-09475.2002","article-title":"Response of neurons in the lateral intraparietal area during a combined visual discrimination reaction time task","volume":"22","author":"Roitman","year":"2002","journal-title":"J Neurosci"},{"issue":"5","key":"2021121215281890000_fcab089-B38","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1093\/cercor\/bhr178","article-title":"Neural correlates of perceptual decision making before, during, and after decision commitment in monkey frontal eye field","volume":"22","author":"Ding","year":"2012","journal-title":"Cereb Cortex"},{"issue":"11","key":"2021121215281890000_fcab089-B39","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.tins.2018.06.005","article-title":"Bridging neural and computational viewpoints on perceptual decision-making","volume":"41","author":"O\u2019Connell","year":"2018","journal-title":"Trends Neurosci"},{"issue":"10","key":"2021121215281890000_fcab089-B40","doi-asserted-by":"crossref","first-page":"5471","DOI":"10.1093\/cercor\/bhaa129","article-title":"Neural correlates of evidence and urgency during human perceptual decision-making in dynamically changing conditions","volume":"30","author":"Yau","year":"2020","journal-title":"Cereb Cortex"},{"issue":"7010","key":"2021121215281890000_fcab089-B41","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1038\/nature02966","article-title":"A general mechanism for perceptual decision-making in the human brain","volume":"431","author":"Heekeren","year":"2004","journal-title":"Nature"},{"issue":"27","key":"2021121215281890000_fcab089-B42","doi-asserted-by":"crossref","first-page":"8675","DOI":"10.1523\/JNEUROSCI.5984-08.2009","article-title":"Domain general mechanisms of perceptual decision making in human cortex","volume":"29","author":"Ho","year":"2009","journal-title":"J Neurosci"},{"issue":"5","key":"2021121215281890000_fcab089-B43","doi-asserted-by":"crossref","first-page":"2383","DOI":"10.1152\/jn.00413.2011","article-title":"Neural correlates of evidence accumulation in a perceptual decision task","volume":"106","author":"Liu","year":"2011","journal-title":"J Neurophysiol"},{"issue":"3","key":"2021121215281890000_fcab089-B44","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1162\/089892902317361886","article-title":"Testing the efficiency and independence of attentional networks","volume":"14","author":"Fan","year":"2002","journal-title":"J Cogn Neurosci"},{"issue":"12","key":"2021121215281890000_fcab089-B45","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1212\/01.wnl.0000187889.17253.b1","article-title":"Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium","volume":"65","author":"McKeith","year":"2005","journal-title":"Neurology"},{"issue":"3","key":"2021121215281890000_fcab089-B46","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.jalz.2011.03.005","article-title":"The diagnosis of dementia due to Alzheimer\u2019s disease: Recommendations from the National Institute on Aging-Alzheimer\u2019s Association workgroups on diagnostic guidelines for Alzheimer\u2019s disease","volume":"7","author":"McKhann","year":"2011","journal-title":"Alzheimers Dement"},{"issue":"6","key":"2021121215281890000_fcab089-B47","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1192\/bjp.149.6.698","article-title":"CAMDEX: A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia","volume":"149","author":"Roth","year":"1986","journal-title":"Br J Psychiatry"},{"issue":"6","key":"2021121215281890000_fcab089-B48","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1159\/000017262","article-title":"Quantification and characterisation of fluctuating cognition in dementia with Lewy bodies and Alzheimer\u2019s disease","volume":"11","author":"Walker","year":"2000","journal-title":"Dement Geriatr Cogn Disord"},{"issue":"2","key":"2021121215281890000_fcab089-B49","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1212\/WNL.62.2.181","article-title":"DLB fluctuations: Specific features that reliably differentiate DLB from AD and normal aging","volume":"62","author":"Ferman","year":"2004","journal-title":"Neurology"},{"issue":"1","key":"2021121215281890000_fcab089-B50","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/mds.25707","article-title":"Fluctuations in cognition and alertness vary independently in dementia with Lewy bodies","volume":"29","author":"Bliwise","year":"2014","journal-title":"Mov Disord"},{"key":"2021121215281890000_fcab089-B51","author":"Cardinal","year":"2006"},{"issue":"5","key":"2021121215281890000_fcab089-B52","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1080\/09541440802205067","article-title":"Methodological and empirical developments for the Ratcliff diffusion model of response times and accuracy","volume":"21","author":"Wagenmakers","year":"2009","journal-title":"Eur J Cogn Psychol"},{"issue":"4","key":"2021121215281890000_fcab089-B53","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.tics.2016.01.007","article-title":"Diffusion decision model: Current issues and history","volume":"20","author":"Ratcliff","year":"2016","journal-title":"Trends Cogn Sci"},{"issue":"8","key":"2021121215281890000_fcab089-B54","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1080\/02699931.2014.985635","article-title":"A Bayesian hierarchical diffusion model decomposition of performance in Approach-Avoidance Tasks","volume":"29","author":"Krypotos","year":"2015","journal-title":"Cogn Emot"},{"key":"2021121215281890000_fcab089-B55","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3389\/fninf.2013.00014","article-title":"HDDM: Hierarchical Bayesian estimation of the drift-diffusion model in Python","volume":"7","author":"Wiecki","year":"2013","journal-title":"Front Neuroinform"},{"issue":"4","key":"2021121215281890000_fcab089-B56","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/1467-9868.00353","article-title":"Bayesian measures of model complexity and fit","volume":"64","author":"Spiegelhalter","year":"2002","journal-title":"J R Stat Soc Ser B Stat Methodol"},{"issue":"4","key":"2021121215281890000_fcab089-B57","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1037\/a0035813","article-title":"Eye tracking and pupillometry are indicators of dissociable latent decision processes","volume":"143","author":"Cavanagh","year":"2014","journal-title":"J Exp Psychol Gen"},{"issue":"7","key":"2021121215281890000_fcab089-B58","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.cub.2016.01.051","article-title":"Neural correlates of decision thresholds in the human subthalamic nucleus","volume":"26","author":"Herz","year":"2016","journal-title":"Curr Biol"},{"issue":"11","key":"2021121215281890000_fcab089-B59","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1038\/nn.2925","article-title":"Subthalamic nucleus stimulation reverses mediofrontal influence over decision threshold","volume":"14","author":"Cavanagh","year":"2011","journal-title":"Nat Neurosci"},{"issue":"2","key":"2021121215281890000_fcab089-B60","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1523\/JNEUROSCI.2036-14.2015","article-title":"fMRI and EEG predictors of dynamic decision parameters during human reinforcement learning","volume":"35","author":"Frank","year":"2015","journal-title":"J Neurosci"},{"issue":"1","key":"2021121215281890000_fcab089-B61","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.neuroimage.2007.07.007","article-title":"A fast diffeomorphic image registration algorithm","volume":"38","author":"Ashburner","year":"2007","journal-title":"NeuroImage"},{"issue":"9","key":"2021121215281890000_fcab089-B62","doi-asserted-by":"crossref","first-page":"2458","DOI":"10.1016\/j.neurobiolaging.2015.05.015","article-title":"Divergent brain functional network alterations in dementia with Lewy bodies and Alzheimer\u2019s disease","volume":"36","author":"Peraza","year":"2015","journal-title":"Neurobiol Aging"},{"issue":"3","key":"2021121215281890000_fcab089-B63","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/j.neuroimage.2011.10.018","article-title":"Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion","volume":"59","author":"Power","year":"2012","journal-title":"NeuroImage"},{"issue":"3","key":"2021121215281890000_fcab089-B64","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1152\/jn.00338.2011","article-title":"The organization of the human cerebral cortex estimated by intrinsic functional connectivity","volume":"106","author":"Yeo","year":"2011","journal-title":"J Neurophysiol"},{"issue":"2","key":"2021121215281890000_fcab089-B65","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.neuroimage.2004.06.035","article-title":"Measuring functional connectivity during distinct stages of a cognitive task","volume":"23","author":"Rissman","year":"2004","journal-title":"NeuroImage"},{"key":"2021121215281890000_fcab089-B66","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.neuroimage.2013.09.018","article-title":"A comparison of statistical methods for detecting context-modulated functional connectivity in fMRI","volume":"84","author":"Cisler","year":"2014","journal-title":"NeuroImage"},{"issue":"8","key":"2021121215281890000_fcab089-B67","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1212\/WNL.54.8.1616","article-title":"Quantifying fluctuation in dementia with Lewy bodies, Alzheimer\u2019s disease, and vascular dementia","volume":"54","author":"Walker","year":"2000","journal-title":"Neurology"},{"issue":"6","key":"2021121215281890000_fcab089-B68","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1001\/archneur.58.6.977","article-title":"Attention and fluctuating attention in patients with dementia with Lewy bodies and Alzheimer disease","volume":"58","author":"Ballard","year":"2001","journal-title":"Arch Neurol"},{"issue":"3","key":"2021121215281890000_fcab089-B69","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1093\/brain\/awh725","article-title":"What best differentiates Lewy body from Alzheimer\u2019s disease in early-stage dementia?","volume":"129","author":"Tiraboschi","year":"2006","journal-title":"Brain"},{"issue":"2","key":"2021121215281890000_fcab089-B70","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1037\/a0018022","article-title":"The effects of aging on the speed\u2013accuracy compromise: Boundary optimality in the diffusion model","volume":"25","author":"Starns","year":"2010","journal-title":"Psychol Aging"},{"issue":"1","key":"2021121215281890000_fcab089-B71","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1037\/0278-7393.32.1.101","article-title":"A diffusion model analysis of adult age differences in episodic and semantic long-term memory retrieval","volume":"32","author":"Spaniol","year":"2006","journal-title":"J Exp Psychol Learn Mem Cogn"},{"issue":"1","key":"2021121215281890000_fcab089-B72","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1037\/0882-7974.22.1.56","article-title":"Application of the diffusion model to two-choice tasks for adults 75\u201390 years old","volume":"22","author":"Ratcliff","year":"2007","journal-title":"Psychol Aging"},{"issue":"3","key":"2021121215281890000_fcab089-B73","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.cogpsych.2009.09.001","article-title":"Individual differences, aging, and IQ in two-choice tasks","volume":"60","author":"Ratcliff","year":"2010","journal-title":"Cogn Psychol"},{"issue":"6","key":"2021121215281890000_fcab089-B74","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1017\/S0140525X05290131","article-title":"Hallucinations and perceptual inference","volume":"28","author":"Friston","year":"2005","journal-title":"Behav Brain Sci"},{"key":"2021121215281890000_fcab089-B75","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.concog.2016.05.003","article-title":"Predictions penetrate perception: Converging insights from brain, behaviour and disorder","volume":"47","author":"O\u2019Callaghan","year":"2017","journal-title":"Conscious Cogn"},{"issue":"1","key":"2021121215281890000_fcab089-B76","doi-asserted-by":"crossref","first-page":"fcz007","DOI":"10.1093\/braincomms\/fcz007","article-title":"Increased weighting on prior knowledge in Lewy body-associated visual hallucinations","volume":"1","author":"Zarkali","year":"2019","journal-title":"Brain Commun"},{"issue":"3","key":"2021121215281890000_fcab089-B77","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1192\/bjp.177.3.252","article-title":"The Clinician Assessment of Fluctuation and the One Day Fluctuation Assessment Scale: Two methods to assess fluctuating confusion in dementia","volume":"177","author":"Walker","year":"2000","journal-title":"Br J Psychiatry"},{"issue":"10","key":"2021121215281890000_fcab089-B78","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1002\/gps.2823","article-title":"Assessment of cognitive fluctuation in dementia: A systematic review of the literature: Cognitive fluctuation in dementia: A systematic review","volume":"27","author":"Lee","year":"2012","journal-title":"Int J Geriatr Psychiatry"},{"issue":"1","key":"2021121215281890000_fcab089-B79","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1093\/brain\/awz311","article-title":"Cognitive fluctuations in Lewy body dementia: Towards a pathophysiological framework","volume":"143","author":"Matar","year":"2020","journal-title":"Brain"},{"issue":"1","key":"2021121215281890000_fcab089-B80","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1469-7580.2005.00426.x","article-title":"The functional organization of the intraparietal sulcus in humans and monkeys","volume":"207","author":"Grefkes","year":"2005","journal-title":"J Anat"},{"issue":"1","key":"2021121215281890000_fcab089-B81","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.neuron.2016.12.003","article-title":"Perceptual decision making in rodents, monkeys, and humans","volume":"93","author":"Hanks","year":"2017","journal-title":"Neuron"},{"issue":"48","key":"2021121215281890000_fcab089-B82","doi-asserted-by":"crossref","first-page":"13082","DOI":"10.1523\/JNEUROSCI.3540-07.2007","article-title":"EEG-informed fMRI reveals spatiotemporal characteristics of perceptual decision making","volume":"27","author":"Philiastides","year":"2007","journal-title":"J Neurosci"},{"key":"2021121215281890000_fcab089-B83","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3389\/fnins.2014.00069","article-title":"Dissociable mechanisms of speed-accuracy tradeoff during visual perceptual learning are revealed by a hierarchical drift-diffusion model","volume":"8","author":"Zhang","year":"2014","journal-title":"Front Neurosci"}],"container-title":["Brain Communications"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/braincomms\/advance-article-pdf\/doi\/10.1093\/braincomms\/fcab089\/37944088\/fcab089.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/braincomms\/article-pdf\/3\/3\/fcab089\/41728286\/fcab089.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/braincomms\/article-pdf\/3\/3\/fcab089\/41728286\/fcab089.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,12]],"date-time":"2021-12-12T10:29:02Z","timestamp":1639304942000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/braincomms\/article\/doi\/10.1093\/braincomms\/fcab089\/6276874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":83,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/braincomms\/fcab089","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.01.07.21249362","asserted-by":"object"}]},"ISSN":["2632-1297"],"issn-type":[{"value":"2632-1297","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021]]},"published":{"date-parts":[[2021]]},"article-number":"fcab089"}}