{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T11:46:24Z","timestamp":1753875984011,"version":"3.41.2"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T00:00:00Z","timestamp":1682294400000},"content-version":"vor","delay-in-days":53,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Multi-Institute Research Faculty","award":["2018:39"],"award-info":[{"award-number":["2018:39"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The Theory of Mind deficit due to cognitive-affective disintegration is a poorly understood cognitive consequence of cortical and subcortical disruption in right temporal lobe epilepsy. Following Marr's trilevel approach, we used the material-specific processing model to understand the Theory of Mind deficit in drug-resistant epilepsy (N = 30). We examined pre- and post-surgery changes in first-order (somatic-affective, non-verbal component) and second-order Theory of Mind (cognitive-verbal component) in three groups formed using: (i) seizure side (right versus left), (ii) right temporal epilepsy (right temporal lobe epilepsy versus non-right temporal lobe epilepsy), and (iii) right temporal lobe epilepsy with amygdalohippocampectomy (right temporal lobe epilepsy versus left temporal lobe epilepsy amygdalohippocampectomy versus non-amygdalohippocampectomy). We observed a marked deficit in the first-order Theory of Mind in the right temporal lobe amygdalohippocampectomy group; we mapped this deficit to decline in the non-verbal component of Theory of Mind (somatic-affective component). Preliminary results support using a material-specific processing model to understand the Theory of Mind deficits in right temporal lobe epilepsy amygdalohippocampectomy. Malleability of verbal processing in presence of deterioration of non-verbal processing might have clinical relevance for post-surgery recovery in right temporal lobe epilepsy amygdalohippocampectomy. Documenting the material-specific nature of deficits (verbal versus non-verbal) in non-western, linguistically, and socioeconomically diverse country enables us to understand the problem of heterogeneity in post-surgery cognitive consequences in the right amygdalohippocampectomy.<\/jats:p>","DOI":"10.1093\/braincomms\/fcad100","type":"journal-article","created":{"date-parts":[[2023,4,24]],"date-time":"2023-04-24T07:31:10Z","timestamp":1682321470000},"source":"Crossref","is-referenced-by-count":1,"title":["Cortico-limbic disruption, material-specificity, and deficits in cognitive-affective theory of mind"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0262-7785","authenticated-orcid":false,"given":"Varsha","family":"Singh","sequence":"first","affiliation":[{"name":"Psychology, Department of Humanities and Social Sciences, Indian Institute of Technology Delhi (IIT) , New Delhi, 110016 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirat S","family":"Grewal","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neurosciences Centre, All India Institute of Medical Sciences, Delhi (AIIMS) , Delhi, New Delhi 110029 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepti","family":"Vibha","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neurosciences Centre, All India Institute of Medical Sciences, Delhi (AIIMS) , Delhi, New Delhi 110029 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajesh K","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neurosciences Centre, All India Institute of Medical Sciences, Delhi (AIIMS) , Delhi, New Delhi 110029 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhargavi","family":"Ramanujam","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neurosciences Centre, All India Institute of Medical Sciences, Delhi (AIIMS) , Delhi, New Delhi 110029 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashima","family":"Nehra","sequence":"additional","affiliation":[{"name":"Neuropsychology, Neurosciences Centre, All India Institute of Medical Sciences (AIIMS) , Delhi, New Delhi 110029 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarat P","family":"Chandra","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS) , Delhi, New Delhi 110029 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shailesh","family":"Gaikwad","sequence":"additional","affiliation":[{"name":"Department of Neuroimaging Interventional Neuroradiology, All India Institute of Medical Sciences (AIIMS) , Delhi, New Delhi 110029 , India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0477-1913","authenticated-orcid":false,"given":"Indupriya","family":"Babu","sequence":"additional","affiliation":[{"name":"The UQIDAR Joint Ph.D. program, Indian Institute of Technology Delhi (IIT) , New Delhi 110016. 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