{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:04:23Z","timestamp":1790193863500,"version":"4.1.0"},"reference-count":70,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"vor","delay-in-days":169,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union\u2019s Horizon 2020 research and innovation program","award":["956673"],"award-info":[{"award-number":["956673"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Functional cognitive disorder is the cognitive subtype of functional neurological disorders. Symptoms are associated with a high level of distress and typically arise due to various risk factors including abnormal focused attention, high memory expectations and poor metacognition. Easily accessible specialized treatments for functional cognitive disorder are needed. Digital interventions are less costly and scalable and allow individuals to engage in self-care in a flexible manner. In this study, we aimed to (i) evaluate the feasibility and safety of a novel self-help digital intervention based on principles of cognitive behavioural therapy and related approaches, (ii) explore preliminary effects of this intervention and (iii) learn about participants\u2019 experience with the intervention. Patients were recruited via a neuropsychiatry clinic. They autonomously completed a 6-week intervention, with phone and email technical support, and were assessed at baseline and at the end of the intervention, using self-reported questionnaires. Besides feasibility outcomes, main measures were the metamemory in adulthood questionnaire, subjective memory complaints, clinical global impression of change, Brief Illness Perception Questionnaire, Behavioural Responses to Illness Questionnaire, Compensatory Cognitive Strategies Questionnaire, depressive and anxiety symptoms, work and social functioning and quality of life. A within-group design was employed. Means, standard deviations and effect sizes were estimated. Post-treatment semi-structured interviews were conducted to further explore the acceptability and usability of the programme. Of the 38 patients eligible, 37 completed the baseline questionnaires (97% recruitment rate). Thirty started the intervention (54% female, mean age 50.4). Four dropped out (4\/30, 13%), with 23\/30 (77%) completing three or more modules, and the attrition rate was 37%. Twenty-seven treatment-related negative effects were reported (5% of total). Overall satisfaction with the programme was high with 62% (16\/26) reporting feeling \u2018satisfied\u2019 or \u2018very satisfied\u2019. Sixteen (62%) reported improvement in their cognitive symptoms (\u2018minimally improved\u2019, \u2018much improved\u2019 and \u2018very much improved\u2019). Paired t-tests showed significant improvements on illness perceptions (mean change \u22126.65, P = 0.001), depressive symptoms (mean change \u22122.96, P = 0.008) and quality of life (mean change 10.06, P = 0.03) at post-treatment. Five patients were dissatisfied with the lack of personalization and found the content unhelpful, with some experiencing increased anxiety. While the intervention met most of its feasibility benchmarks, efficacy needs to be explored in a future randomized controlled trial. Self-help digital therapy may be a flexible and cost-effective option to increase availability and accessibility of specialized treatment for functional cognitive disorder, within a stepped care model, as a complement to other multidisciplinary face-to-face interventions.<\/jats:p>","DOI":"10.1093\/braincomms\/fcaf248","type":"journal-article","created":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T15:07:31Z","timestamp":1751036851000},"source":"Crossref","is-referenced-by-count":4,"title":["Feasibility trial of a self-help digital intervention for functional cognitive disorder"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9945-7681","authenticated-orcid":false,"given":"Ver\u00f3nica","family":"Cabreira","sequence":"first","affiliation":[{"name":"Centre for Clinical Brain Sciences, University of Edinburgh , Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisbeth","family":"Frostholm","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Aarhus University , Palle Juul-Jensens Boulevard 118200 Aarhus N ,","place":["Denmark"]},{"name":"Department of Functional Disorders, Aarhus University Hospital , Palle Juul-Jensen Boulevard 11DK-8200 Aarhus N ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9829-8092","authenticated-orcid":false,"given":"Jon","family":"Stone","sequence":"additional","affiliation":[{"name":"Centre for Clinical Brain Sciences, University of Edinburgh , Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7425-0964","authenticated-orcid":false,"given":"Alan","family":"Carson","sequence":"additional","affiliation":[{"name":"Centre for Clinical Brain Sciences, University of Edinburgh , Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,6,19]]},"reference":[{"issue":"10","key":"2025082607522901300_fcaf248-B1","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1093\/brain\/awaa224","article-title":"Functional cognitive disorder: Dementia's blind spot","volume":"143","author":"Ball","year":"2020","journal-title":"Brain"},{"issue":"5","key":"2025082607522901300_fcaf248-B2","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1002\/gps.5466","article-title":"Functional cognitive disorder in subjective cognitive decline-A 10-year follow-up","volume":"36","author":"Schwilk","year":"2021","journal-title":"Int J Geriatr Psychiatry"},{"issue":"2","key":"2025082607522901300_fcaf248-B3","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1080\/13546805.2019.1590190","article-title":"Clinical presentation and neuropsychological profiles of functional cognitive disorder patients with and without co-morbid depression","volume":"24","author":"Bhome","year":"2019","journal-title":"Cogn Neuropsychiatry."},{"key":"2025082607522901300_fcaf248-B4","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.3233\/JAD-150430","article-title":"Functional (psychogenic) cognitive disorders: A perspective from the neurology clinic","volume":"48 Suppl 1","author":"Stone","year":"2015","journal-title":"J Alzheimers Dis"},{"issue":"12","key":"2025082607522901300_fcaf248-B5","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1136\/jnnp-2017-317823","article-title":"A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome: Systematic review","volume":"89","author":"Teodoro","year":"2018","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"2025082607522901300_fcaf248-B6","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.ncl.2023.02.004","article-title":"Functional cognitive disorder: Diagnosis, treatment, and differentiation from secondary causes of cognitive difficulties","volume":"41","author":"Cabreira","year":"2023","journal-title":"Neurol Clin."},{"key":"2025082607522901300_fcaf248-B7","doi-asserted-by":"crossref","first-page":"111447","DOI":"10.1016\/j.jpsychores.2023.111447","article-title":"Clinical signs in functional cognitive disorders: A systematic review and diagnostic meta-analysis","volume":"173","author":"Cabreira","year":"2023","journal-title":"J Psychosom Res"},{"issue":"4","key":"2025082607522901300_fcaf248-B8","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1159\/000128166","article-title":"A pilot group therapy for functional memory disorder","volume":"77","author":"Metternich","year":"2008","journal-title":"Psychother Psychosom"},{"issue":"1","key":"2025082607522901300_fcaf248-B9","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1159\/000254901","article-title":"The effects of nonpharmacological interventions on subjective memory complaints: A systematic review and meta-analysis","volume":"79","author":"Metternich","year":"2010","journal-title":"Psychother Psychosom"},{"issue":"5","key":"2025082607522901300_fcaf248-B10","doi-asserted-by":"crossref","first-page":"e072366","DOI":"10.1136\/bmjopen-2023-072366","article-title":"Feasibility randomised controlled trial of online group acceptance and commitment therapy for functional cognitive disorder (ACT4FCD)","volume":"13","author":"Norman","year":"2023","journal-title":"BMJ Open"},{"issue":"2","key":"2025082607522901300_fcaf248-B11","doi-asserted-by":"crossref","first-page":"e000666","DOI":"10.1136\/bmjno-2024-000666","article-title":"Pilot feasibility randomised controlled trial of cognitive-behavioural therapy for functional cognitive disorder after concussion","volume":"6","author":"Rioux","year":"2024","journal-title":"BMJ Neurol Open."},{"key":"2025082607522901300_fcaf248-B12","doi-asserted-by":"publisher","author":"Cotton","DOI":"10.1101\/2024.10.15.24315532"},{"key":"2025082607522901300_fcaf248-B13","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/psyg.12232","article-title":"How the UK describes functional memory symptoms","volume":"17","author":"Bailey","year":"2017","journal-title":"Psychogeriatrics"},{"key":"2025082607522901300_fcaf248-B14","doi-asserted-by":"crossref","first-page":"e16318","DOI":"10.1111\/ene.16318","article-title":"Perspectives on the diagnosis and management of functional cognitive disorder: An international Delphi study","volume":"32","author":"Cabreira","year":"2024","journal-title":"Eur J Neurol."},{"key":"2025082607522901300_fcaf248-B15","doi-asserted-by":"crossref","first-page":"106504","DOI":"10.1016\/j.yebeh.2019.106504","article-title":"The impact of a depression self-management intervention on seizure activity","volume":"103","author":"Thompson","year":"2020","journal-title":"Epilepsy Behav."},{"issue":"6","key":"2025082607522901300_fcaf248-B16","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.brat.2012.03.001","article-title":"A pilot randomised controlled trial of an internet-based cognitive behavioural therapy self-management programme (MS Invigor8) for multiple sclerosis fatigue","volume":"50","author":"Moss-Morris","year":"2012","journal-title":"Behav Res Ther"},{"issue":"6","key":"2025082607522901300_fcaf248-B17","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1212\/WNL.0b013e318228c0c7","article-title":"Guided self-help for functional (psychogenic) symptoms: A randomized controlled efficacy trial","volume":"77","author":"Sharpe","year":"2011","journal-title":"Neurology"},{"key":"2025082607522901300_fcaf248-B18","doi-asserted-by":"crossref","first-page":"100469","DOI":"10.1016\/j.ebr.2021.100469","article-title":"Remote delivery of cognitive behavioral therapy to patients with functional neurological disorders: Promise and challenges","volume":"16","author":"Lin","year":"2021","journal-title":"Epilepsy Behav Rep."},{"issue":"13","key":"2025082607522901300_fcaf248-B19","doi-asserted-by":"crossref","first-page":"e1883","DOI":"10.1212\/WNL.0000000000010381","article-title":"Internet-based self-help randomized trial for motor functional neurologic disorder (SHIFT)","volume":"95","author":"Gelauff","year":"2020","journal-title":"Neurology"},{"issue":"5","key":"2025082607522901300_fcaf248-B20","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1001\/jamapsychiatry.2017.0262","article-title":"Needed innovation in digital health and smartphone applications for mental health: Transparency and trust","volume":"74","author":"Torous","year":"2017","journal-title":"JAMA psychiatry"},{"key":"2025082607522901300_fcaf248-B21","doi-asserted-by":"crossref","first-page":"e43557","DOI":"10.2196\/43557","article-title":"A digital health intervention for concussion: Development and clinical feasibility study","volume":"7","author":"d'Offay","year":"2023","journal-title":"JMIR Form Res."},{"issue":"10","key":"2025082607522901300_fcaf248-B22","doi-asserted-by":"crossref","first-page":"e11231","DOI":"10.2196\/11231","article-title":"Benefits of mobile apps in pain management: Systematic review","volume":"6","author":"Thurnheer","year":"2018","journal-title":"JMIR Mhealth Uhealth."},{"key":"2025082607522901300_fcaf248-B23","doi-asserted-by":"publisher","DOI":"10.2139\/ssrn.3410908","article-title":"Efficacy of internet-delivered acceptance and commitment therapy for severe health anxiety: Results from a randomized, controlled trial","author":"Hoffmann","year":"2019","journal-title":"SSRN Electron J"},{"key":"2025082607522901300_fcaf248-B24","doi-asserted-by":"crossref","first-page":"100214","DOI":"10.1016\/j.eclinm.2019.11.007","article-title":"Novel interdisciplinary intervention, GAIN, vs. Enhanced usual care to reduce high levels of post-concussion symptoms in adolescents and young adults 2\u20136 months post-injury: A randomised trial","volume":"17","author":"Thastum","year":"2019","journal-title":"EClinicalMedicine"},{"issue":"2","key":"2025082607522901300_fcaf248-B25","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s41347-019-00095-w","article-title":"Creating a digital health smartphone app and digital phenotyping platform for mental health and diverse healthcare needs: An interdisciplinary and collaborative approach","volume":"4","author":"Torous","year":"2019","journal-title":"J Technol Behav Sci."},{"issue":"1","key":"2025082607522901300_fcaf248-B26","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/s41746-024-01280-9","article-title":"Systematic review and meta-analysis of standalone digital interventions for cognitive symptoms in people without dementia","volume":"7","author":"Cabreira","year":"2024","journal-title":"NPJ Digit Med."},{"key":"2025082607522901300_fcaf248-B27","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s40814-016-0105-8","article-title":"CONSORT 2010 statement: Extension to randomised pilot and feasibility trials","volume":"2","author":"Eldridge","year":"2016","journal-title":"Pilot Feasibility Stud."},{"key":"2025082607522901300_fcaf248-B28","doi-asserted-by":"publisher","author":"Cabreira","DOI":"10.2196\/preprints.76263"},{"issue":"1","key":"2025082607522901300_fcaf248-B29","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1017\/bec.2018.9","article-title":"Effects of a focused breathing mindfulness exercise on attention, memory, and mood: The importance of task characteristics","volume":"35","author":"Eisenbeck","year":"2018","journal-title":"Behav Change."},{"issue":"4","key":"2025082607522901300_fcaf248-B30","doi-asserted-by":"crossref","first-page":"e0153309","DOI":"10.1371\/journal.pone.0153309","article-title":"Mindfulness enhances episodic memory performance: Evidence from a multimethod investigation","volume":"11","author":"Brown","year":"2016","journal-title":"PLoS One"},{"issue":"10","key":"2025082607522901300_fcaf248-B31","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/s44159-022-00090-8","article-title":"A common factors perspective on mindfulness-based interventions","volume":"1","author":"Goldberg","year":"2022","journal-title":"Nat Rev Psychol."},{"key":"2025082607522901300_fcaf248-B32","doi-asserted-by":"crossref","first-page":"n2061","DOI":"10.1136\/bmj.n2061","article-title":"A new framework for developing and evaluating complex interventions: Update of medical research council guidance","volume":"374","author":"Skivington","year":"2021","journal-title":"BMJ"},{"key":"2025082607522901300_fcaf248-B33","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0005-7916(00)00012-4","article-title":"Psychometric properties of the credibility\/expectancy questionnaire","volume":"31","author":"Devilly","year":"2000","journal-title":"J Behav Ther Exp Psychiatry."},{"key":"2025082607522901300_fcaf248-B34","doi-asserted-by":"crossref","first-page":"e234","DOI":"10.2196\/jmir.5952","article-title":"Reliability and validity of assessing user satisfaction with web-based health interventions","volume":"18","author":"Bo\u00df","year":"2016","journal-title":"J Med Internet Res."},{"issue":"5","key":"2025082607522901300_fcaf248-B35","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1017\/S1352465819000018","article-title":"The negative effects questionnaire: Psychometric properties of an instrument for assessing negative effects in psychological treatments","volume":"47","author":"Rozental","year":"2019","journal-title":"Behav Cogn Psychother"},{"issue":"4","key":"2025082607522901300_fcaf248-B36","doi-asserted-by":"crossref","first-page":"e11500","DOI":"10.2196\/11500","article-title":"The mHealth app usability questionnaire (MAUQ): Development and validation study","volume":"7","author":"Zhou","year":"2019","journal-title":"JMIR Mhealth Uhealth."},{"issue":"7","key":"2025082607522901300_fcaf248-B37","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1080\/13607863.2019.1594160","article-title":"Refining the metamemory in adulthood questionnaire: A 20-item version of change and capacity designed for research and clinical settings","volume":"24","author":"McDonough","year":"2020","journal-title":"Aging Ment Health."},{"issue":"6","key":"2025082607522901300_fcaf248-B38","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.jpsychores.2005.10.020","article-title":"The brief illness perception questionnaire","volume":"60","author":"Broadbent","year":"2006","journal-title":"J Psychosom Res"},{"key":"2025082607522901300_fcaf248-B39","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1017\/S0033291704003484","article-title":"The behavioural responses to illness questionnaire (BRIQ): A new predictive measure of medically unexplained symptoms following acute infection","volume":"35","author":"Spence","year":"2005","journal-title":"Psychol Med."},{"issue":"14","key":"2025082607522901300_fcaf248-B40","doi-asserted-by":"crossref","first-page":"6817","DOI":"10.1017\/S0033291723000338","article-title":"The wellbeing neuro course: A randomised controlled trial of an internet-delivered transdiagnostic psychological intervention for adults with neurological disorders","volume":"353","author":"Gandy","year":"202","journal-title":"Psychol Med."},{"issue":"9","key":"2025082607522901300_fcaf248-B41","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1046\/j.1525-1497.2001.016009606.x","article-title":"The PHQ-9: Validity of a brief depression severity measure","volume":"16","author":"Kroenke","year":"2001","journal-title":"J Gen Intern Med."},{"issue":"8","key":"2025082607522901300_fcaf248-B42","doi-asserted-by":"crossref","first-page":"e0182162","DOI":"10.1371\/journal.pone.0182162","article-title":"Psychometric analysis of the Generalized Anxiety Disorder scale (GAD-7) in primary care using modern item response theory","volume":"12","author":"Jordan","year":"2017","journal-title":"PLoS One"},{"issue":"3","key":"2025082607522901300_fcaf248-B43","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1007\/s11136-020-02688-y","article-title":"Psychometric properties of the EQ-5D-5L: A systematic review of the literature","volume":"30","author":"Feng","year":"2021","journal-title":"Qual Life Res."},{"issue":"5","key":"2025082607522901300_fcaf248-B44","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1192\/bjp.180.5.461","article-title":"The work and social adjustment scale: A simple measure of impairment in functioning","volume":"180","author":"Mundt","year":"2018","journal-title":"Br J Psychiatry"},{"issue":"7","key":"2025082607522901300_fcaf248-B45","first-page":"28","article-title":"The clinical global impressions scale: Applying a research tool in clinical practice","volume":"4","author":"Busner","year":"2007","journal-title":"Psychiatry (Edgmont)"},{"issue":"11","key":"2025082607522901300_fcaf248-B46","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.jclinepi.2015.04.014","article-title":"A simple formula for the calculation of sample size in pilot studies","volume":"68","author":"Viechtbauer","year":"2015","journal-title":"J Clin Epidemiol."},{"issue":"1","key":"2025082607522901300_fcaf248-B47","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1365-2648.2007.04569.x","article-title":"The qualitative content analysis process","volume":"62","author":"Elo","year":"2008","journal-title":"J Adv Nurs."},{"issue":"3","key":"2025082607522901300_fcaf248-B48","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1080\/14780887.2020.1769238","article-title":"One size fits all? What counts as quality practice in (reflexive) thematic analysis?","volume":"18","author":"Braun","year":"2021","journal-title":"Qual Res Psychol."},{"issue":"9","key":"2025082607522901300_fcaf248-B49","doi-asserted-by":"crossref","first-page":"e14567","DOI":"10.2196\/14567","article-title":"Objective user engagement with mental health apps: Systematic search and panel-based usage analysis","volume":"21","author":"Baumel","year":"2019","journal-title":"J Med Internet Res."},{"issue":"3","key":"2025082607522901300_fcaf248-B50","doi-asserted-by":"crossref","first-page":"e0000219","DOI":"10.1371\/journal.pdig.0000219","article-title":"Exploring how informed mental health app selection may impact user engagement and satisfaction","volume":"2","author":"Kopka","year":"2023","journal-title":"PLoS Digit Health."},{"issue":"1","key":"2025082607522901300_fcaf248-B51","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s44247-024-00105-9","article-title":"Engagement and retention in digital mental health interventions: A narrative review","volume":"2","author":"Boucher","year":"2024","journal-title":"BMC Digit Health."},{"issue":"3","key":"2025082607522901300_fcaf248-B52","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/ana.3000","article-title":"Outcome in psychogenic nonepileptic seizures: 1 to 10-year follow-up in 164 patients","volume":"53","author":"Reuber","year":"2003","journal-title":"Ann Neurol."},{"issue":"1","key":"2025082607522901300_fcaf248-B53","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/s41746-021-00386-8","article-title":"Smartphone apps for depression and anxiety: A systematic review and meta-analysis of techniques to increase engagement","volume":"4","author":"Wu","year":"2021","journal-title":"NPJ Digit Med."},{"issue":"2","key":"2025082607522901300_fcaf248-B54","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S2215-0366(15)00565-9","article-title":"The digital placebo effect: Mobile mental health meets clinical psychiatry","volume":"3","author":"Torous","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"3","key":"2025082607522901300_fcaf248-B55","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.brat.2009.01.010","article-title":"Using the internet to provide cognitive behaviour therapy","volume":"47","author":"Andersson","year":"2009","journal-title":"Behav Res Ther"},{"key":"2025082607522901300_fcaf248-B56","doi-asserted-by":"crossref","first-page":"100448","DOI":"10.1016\/j.invent.2021.100448","article-title":"The effect of user interface on treatment engagement in a self-guided digital problem-solving intervention: A randomized controlled trial","volume":"26","author":"Hentati","year":"2021","journal-title":"Internet Interv."},{"issue":"5","key":"2025082607522901300_fcaf248-B57","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1002\/cpp.2851","article-title":"Conceptualizing the digital therapeutic alliance in the context of fully automated mental health apps: A thematic analysis","volume":"30","author":"Tong","year":"2023","journal-title":"Clin Psychol Psychother."},{"key":"2025082607522901300_fcaf248-B58","doi-asserted-by":"crossref","first-page":"716106","DOI":"10.3389\/fpsyg.2021.716106","article-title":"The influence of human support on the effectiveness of digital mental health promotion interventions for the general population","volume":"12","author":"Renfrew","year":"2021","journal-title":"Front Psychol."},{"issue":"2","key":"2025082607522901300_fcaf248-B59","doi-asserted-by":"crossref","first-page":"fcac041","DOI":"10.1093\/braincomms\/fcac041","article-title":"Metacognition in functional cognitive disorder","volume":"4","author":"Bhome","year":"2022","journal-title":"Brain Commun."},{"issue":"6","key":"2025082607522901300_fcaf248-B60","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/S2215-0366(20)30128-0","article-title":"Cognitive behavioural therapy for adults with dissociative seizures (CODES): A pragmatic, multicentre, randomised controlled trial","volume":"7","author":"Goldstein","year":"2020","journal-title":"Lancet Psychiatry."},{"issue":"7","key":"2025082607522901300_fcaf248-B61","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/S1474-4422(24)00135-2","article-title":"Specialist physiotherapy for functional motor disorder in England and Scotland (Physio4FMD): A pragmatic, multicentre, phase 3 randomised controlled trial","volume":"23","author":"Nielsen","year":"2024","journal-title":"Lancet Neurol."},{"issue":"3","key":"2025082607522901300_fcaf248-B62","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S2215-0366(25)00006-9","article-title":"The most important aims of psychotherapy: To love, to work, and to find meaning","volume":"12","author":"Zavlis","year":"2025","journal-title":"Lancet Psychiatry."},{"key":"2025082607522901300_fcaf248-B63","doi-asserted-by":"crossref","first-page":"109485","DOI":"10.1016\/j.yebeh.2023.109485","article-title":"I just need to know what they are and if you can help me\u2019: Medicalization and the search for legitimacy in people diagnosed with non-epileptic attack disorder","volume":"148","author":"Peacock","year":"2023","journal-title":"Epilepsy Behav."},{"issue":"2","key":"2025082607522901300_fcaf248-B64","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10916-014-0182-2","article-title":"Empirical studies on usability of mHealth apps: A systematic literature review","volume":"39","author":"Zapata","year":"2015","journal-title":"J Med Syst."},{"issue":"2","key":"2025082607522901300_fcaf248-B65","doi-asserted-by":"crossref","first-page":"e13080","DOI":"10.2196\/13080","article-title":"Evaluation of self-management support functions in apps for people with persistent pain: Systematic review","volume":"7","author":"Devan","year":"2019","journal-title":"JMIR Mhealth Uhealth."},{"issue":"1","key":"2025082607522901300_fcaf248-B66","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/s41746-023-00809-8","article-title":"Internet-based and mobile-based cognitive behavioral therapy for chronic diseases: A systematic review and meta-analysis","volume":"6","author":"Tao","year":"2023","journal-title":"NPJ Digit Med."},{"issue":"2","key":"2025082607522901300_fcaf248-B67","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s10865-018-9984-x","article-title":"Internet-delivered cognitive behaviour therapy for chronic health conditions: A systematic review and meta-analysis","volume":"42","author":"Mehta","year":"2019","journal-title":"J Behav Med."},{"issue":"8","key":"2025082607522901300_fcaf248-B68","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1161\/STROKEAHA.120.029042","article-title":"Telemedicine cognitive behavioral therapy for anxiety after stroke: Proof-of-concept randomized controlled trial","volume":"51","author":"Chun","year":"2020","journal-title":"Stroke"},{"issue":"2","key":"2025082607522901300_fcaf248-B69","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1017\/neu.2017.21","article-title":"Distinctive neuropsychological profiles differentiate patients with functional memory disorder from patients with amnestic-mild cognitive impairment","volume":"30","author":"Wakefield","year":"2018","journal-title":"Acta Neuropsychiatr."},{"key":"2025082607522901300_fcaf248-B70","author":"Centre for Sustainable Delivery NHS Scotland","year":"2024"}],"container-title":["Brain Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/braincomms\/advance-article-pdf\/doi\/10.1093\/braincomms\/fcaf248\/63525563\/fcaf248.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/braincomms\/article-pdf\/7\/4\/fcaf248\/63525563\/fcaf248.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/braincomms\/article-pdf\/7\/4\/fcaf248\/63525563\/fcaf248.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T11:52:43Z","timestamp":1756209163000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/braincomms\/article\/doi\/10.1093\/braincomms\/fcaf248\/8169066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":70,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7,3]]}},"URL":"https:\/\/doi.org\/10.1093\/braincomms\/fcaf248","relation":{},"ISSN":["2632-1297"],"issn-type":[{"value":"2632-1297","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025]]},"published":{"date-parts":[[2025]]},"article-number":"fcaf248"}}