{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T08:58:57Z","timestamp":1793091537605,"version":"4.5.0"},"reference-count":146,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":301,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The treatment of chronic pain represents a widespread clinical challenge. Current approaches to network-based mapping of the cerebral cortex have the potential to localize chronic pain in the brain. In an effort to further characterize the dynamical brain networks, or the \u2018dynome\u2019 in the setting of chronic pain, we performed a Coordinate-Based Meta-Analysis of resting-state functional Magnetic Resonance Imaging studies on chronic pain to create a multinetwork dynome of chronic pain. A cluster-level analysis generated seven statistically significant activation likelihood estimates (ALEs): one for chronic pain as a whole dynome, three for chronic pain conditions, and three for chronic pain mechanisms. Chronic pain is a complex disease process involving tripartite network dysfunction encompassing the Default Mode Network, Central Executive Network and Salience Network. Chronic visceral pain was distinct from chronic headache and chronic musculoskeletal pain, and chronic pain mechanisms have the potential to share common cortical network rearrangements with their respective chronic pain conditions. Collectively, this work represents the first anatomically specific network-based cortical map of chronic pain, with representation of disease-specific and mechanism-specific disruptions in cortical function.<\/jats:p>","DOI":"10.1093\/braincomms\/fcaf343","type":"journal-article","created":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T12:41:59Z","timestamp":1761482519000},"source":"Crossref","is-referenced-by-count":10,"title":["Multi-network dynamical structure of the human brain in the setting of chronic pain: a coordinate-based meta-analysis"],"prefix":"10.1093","volume":"7","author":[{"given":"Vukshitha","family":"Dhanaraj","sequence":"first","affiliation":[{"name":"Centre for Minimally Invasive Neurosurgery, Prince of Wales Private Hospital, Suite 19, Level 7 Prince of Wales Private Hospital, Randwick , Sydney, NSW 2031 ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathaniel W","family":"Rolfe","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Columbia University Irving Medical Center\/NY-Presbyterian Hospital , New York, NY 10032 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8657-187X","authenticated-orcid":false,"given":"Nicholas B","family":"Dadario","sequence":"additional","affiliation":[{"name":"Robert Wood Johnson Medical School, Rutgers University , New Brunswick, NJ 08901 ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasneet","family":"Dhaliwal","sequence":"additional","affiliation":[{"name":"UCL Medical School, University College London , London WC1E 6BT ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nardin","family":"Samuel","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, University of Toronto , Toronto \u00a0 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