{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T08:58:50Z","timestamp":1776416330492,"version":"3.51.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":97,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Royal National Institute for Deaf","award":["S52_Bajo"],"award-info":[{"award-number":["S52_Bajo"]}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["WT108369\/Z\/2015\/Z"],"award-info":[{"award-number":["WT108369\/Z\/2015\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,3]]},"abstract":"<jats:p>N,N-Diisopropyltryptamine (DiPT) is a frequency-selective pitch-distorting psychedelic drug that induces a downward shift in perception where the auditory world of the subject sounds lower in pitch than in a sober state of consciousness. Hurst and Bajo propose the neural mechanisms for this effect and its use as potential therapeutic for tinnitus.<\/jats:p>","DOI":"10.1093\/braincomms\/fcag093","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T11:41:51Z","timestamp":1775043711000},"source":"Crossref","is-referenced-by-count":0,"title":["<i>N<\/i>\n                    ,\n                    <i>N<\/i>\n                    -Diisopropyltryptamine and diptogenia: proposed mechanisms for a frequency-selective pitch-distorting psychedelic"],"prefix":"10.1093","volume":"8","author":[{"given":"Aidan","family":"Hurst","sequence":"first","affiliation":[{"name":"Department of Physiology, Anatomy and Genetics, University of Oxford , Oxford OX1 3PT ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3612-2048","authenticated-orcid":false,"given":"Victoria M","family":"Bajo","sequence":"additional","affiliation":[{"name":"Department of Physiology, Anatomy and Genetics, University of Oxford , Oxford OX1 3PT ,","place":["UK"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"issue":"3","key":"2026041703583176900_fcag093-B1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1080\/02791072.2001.10400574","article-title":"Pharma\u00f1opo\u2014Psychonautics: Human intranasal, sublingual, intrarectal, pulmonary and oral pharmacology of bufotenine","volume":"33","author":"Ott","year":"2001","journal-title":"J Psychoact Drugs"},{"issue":"5239","key":"2026041703583176900_fcag093-B2","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1038\/2251207a0","article-title":"Travelling waves as frequency analysers in the cochlea","volume":"225","author":"Von B\u00e9k\u00e9sy","year":"1970","journal-title":"Nature"},{"key":"2026041703583176900_fcag093-B3","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/B978-0-444-62630-1.00001-9","article-title":"Auditory pathways: anatomy and physiology","volume":"129","author":"Pickles","year":"2015","journal-title":"Handb Clin Neurol"},{"issue":"4","key":"2026041703583176900_fcag093-B4","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1152\/jn.1967.30.4.769","article-title":"Phase-locked response to low-frequency tones in single auditory nerve fibers of the squirrel monkey","volume":"30","author":"Rose","year":"1967","journal-title":"J Neurophysiol"},{"issue":"2\u20136","key":"2026041703583176900_fcag093-B5","doi-asserted-by":"crossref","first-page":"186","DOI":"10.3109\/00016486509124552","article-title":"Stimulus coding in the auditory nerve and cochlear nucleus","volume":"59","author":"Kiang","year":"1965","journal-title":"Acta Oto Laryngol"},{"issue":"6","key":"2026041703583176900_fcag093-B6","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1021\/jm00342a019","article-title":"Synthesis and pharmacological activity of fluorinated tryptamine derivatives","volume":"6","author":"Kalir","year":"1963","journal-title":"J Med Chem"},{"issue":"4","key":"2026041703583176900_fcag093-B7","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1097\/MAO.0b013e318254501b","article-title":"Dexamethasone levels and base-to-apex concentration gradients in the scala tympani perilymph after intracochlear delivery in the guinea pig","volume":"33","author":"Hahn","year":"2012","journal-title":"Otol Neurotol"},{"issue":"3","key":"2026041703583176900_fcag093-B8","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1124\/jpet.114.219337","article-title":"Tolerance and cross-tolerance to head twitch behavior elicited by phenethylamine- and tryptamine-derived hallucinogens in mice","volume":"351","author":"Smith","year":"2014","journal-title":"J Pharmacol Exp Ther"},{"issue":"2","key":"2026041703583176900_fcag093-B9","doi-asserted-by":"crossref","first-page":"e9019","DOI":"10.1371\/journal.pone.0009019","article-title":"Psychedelics and the human receptorome","volume":"5","author":"Ray","year":"2010","journal-title":"PLoS One"},{"issue":"12","key":"2026041703583176900_fcag093-B10","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1007\/s00702-009-0308-8","article-title":"Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter","volume":"116","author":"Cozzi","year":"2009","journal-title":"J Neural Transm"}],"container-title":["Brain Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/braincomms\/article-pdf\/8\/2\/fcag093\/68101144\/fcag093.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/braincomms\/article-pdf\/8\/2\/fcag093\/68101144\/fcag093.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T08:00:31Z","timestamp":1776412831000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/braincomms\/article\/doi\/10.1093\/braincomms\/fcag093\/8644266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3,3]]}},"URL":"https:\/\/doi.org\/10.1093\/braincomms\/fcag093","relation":{},"ISSN":["2632-1297"],"issn-type":[{"value":"2632-1297","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026]]},"published":{"date-parts":[[2026]]},"article-number":"fcag093"}}