{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:59:14Z","timestamp":1793224754305,"version":"4.5.0"},"reference-count":136,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":239,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002326","name":"University of Stirling","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002326","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Parkinson\u2019s disease is characterized by a range of motor and non-motor changes that can negatively impact quality of life. Many studies have identified potential clinical electrophysiological correlates of Parkinson\u2019s disease with an aim of developing new methods of identifying at-risk patients and forming the basis of therapeutic interventions. However, these studies do not present consistent results, and a formal meta-analysis is warranted to identify reliable EEG or magnetoencephalography (M\/EEG) characteristics across datasets. In this meta-analysis of open-access M\/EEG datasets (n = 6; 4 EEG and 2 MEG), we compared periodic and aperiodic characteristics of resting-state recordings in 368 patients with Parkinson\u2019s disease and 570 age-matched healthy controls. Specifically, we compared the power and peak frequency of unadjusted and aperiodic-adjusted alpha- and beta-band oscillations, and the exponent and offset, across the two groups. Parkinson\u2019s patients had a consistently elevated aperiodic exponent and offset. Patients also had higher unadjusted beta-band power, but this was no longer present when the aperiodic features were removed, suggesting that previous findings of elevated beta activity in Parkinson\u2019s disease could be confounded by aperiodic activity rather than reflecting true oscillatory differences. Patients also had higher adjusted and unadjusted alpha-band power and a slower alpha peak frequency compared with controls, whereas no group difference in beta peak frequency was identified. In conclusion, this large cohort meta-analysis points to a broadly consistent pattern of both periodic and aperiodic changes in Parkinson\u2019s patients in M\/EEG signals that may be used to develop diagnostics and targeted interventions in the future.<\/jats:p>","DOI":"10.1093\/braincomms\/fcag329","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T12:45:42Z","timestamp":1787921142000},"source":"Crossref","is-referenced-by-count":2,"title":["A meta-analysis of periodic and aperiodic electrophysiological features in Parkinson\u2019s disease"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1312-3398","authenticated-orcid":false,"given":"Hamzeh","family":"Norouzi","sequence":"first","affiliation":[{"name":"School of Psychology, University of Stirling , Stirling FK9 4LA, Scotland 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