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Various oxygen supply treatments are used in clinical practice to improve the hypoxic environment at the wound site. However, problems still occur, such as insufficient oxygen supply, short oxygen infusion time and potential biosafety risks. In recent years, artificial photosynthetic systems have become a research hotspot in the fields of materials and energy. Photosynthesis is expected to improve the oxygen level at wound sites and promote wound healing because the method provides a continuous oxygen supply and has good biosafety. In this paper, oxygen treatment methods for wounds are reviewed, and the oxygen supply principle and construction of artificial photosynthesis systems are described. Finally, research progress on the photosynthetic oxygen production system to promote wound healing is summarized.<\/jats:p>","DOI":"10.1093\/burnst\/tkae012","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T12:16:01Z","timestamp":1718021761000},"source":"Crossref","is-referenced-by-count":30,"title":["Hypoxic environment of wounds and photosynthesis-based oxygen therapy"],"prefix":"10.1093","volume":"12","author":[{"given":"Shuning","family":"Tian","sequence":"first","affiliation":[{"name":"Jiangsu Engineering Research Center for Efficient Delivery System of TCM , School of Pharmacy, , 138 Xianlin Avenue, Qixia District, Nanjing 210023 , China"},{"name":"Nanjing University of Chinese Medicine , School of Pharmacy, , 138 Xianlin Avenue, Qixia District, Nanjing 210023 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenyu","family":"Tan","sequence":"additional","affiliation":[{"name":"Jiangsu Engineering Research Center for Efficient Delivery System of TCM , School of Pharmacy, , 138 Xianlin Avenue, Qixia District, Nanjing 210023 , China"},{"name":"Nanjing University of Chinese Medicine , School of Pharmacy, , 138 Xianlin Avenue, Qixia District, Nanjing 210023 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingjie","family":"Fan","sequence":"additional","affiliation":[{"name":"Jiangsu Engineering Research Center for Efficient Delivery System of TCM , School of Pharmacy, , 138 Xianlin Avenue, Qixia District, Nanjing 210023 , China"},{"name":"Nanjing University of Chinese Medicine , School of Pharmacy, , 138 Xianlin Avenue, Qixia District, Nanjing 210023 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenlin","family":"Gong","sequence":"additional","affiliation":[{"name":"Jiangsu Engineering Research Center for Efficient Delivery System of TCM , School of Pharmacy, , 138 Xianlin Avenue, Qixia District, Nanjing 210023 , China"},{"name":"Nanjing University of 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