{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T17:56:01Z","timestamp":1769018161597,"version":"3.49.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1093\/carcin\/bgt021","type":"journal-article","created":{"date-parts":[[2013,1,29]],"date-time":"2013-01-29T02:04:46Z","timestamp":1359425086000},"page":"1158-1164","source":"Crossref","is-referenced-by-count":29,"title":["Basal stem cells contribute to squamous cell carcinomas in the oral cavity"],"prefix":"10.1093","volume":"34","author":[{"given":"Xiao-Han","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa","family":"Scognamiglio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine J.","family":"Gudas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2013,1,28]]},"reference":[{"key":"key\n\t\t\t\t20170520230942_CIT0001","doi-asserted-by":"crossref","first-page":"212","DOI":"10.3322\/caac.20121","article-title":"Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths","volume":"61","author":"Siegel","year":"2011","journal-title":"CA Cancer J. Clin"},{"key":"key\n\t\t\t\t20170520230942_CIT0002","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1600-0714.1983.tb00312.x","article-title":"Etiology of oral squamous cell carcinoma","volume":"12","author":"Binnie","year":"1983","journal-title":"J. Oral Pathol"},{"key":"key\n\t\t\t\t20170520230942_CIT0003","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1200\/JCO.2005.09.128","article-title":"Oral cancer prevention and the evolution of molecular-targeted drug development","volume":"23","author":"Lippman","year":"2005","journal-title":"J. Clin. Oncol"},{"key":"key\n\t\t\t\t20170520230942_CIT0004","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.oraloncology.2006.04.016","article-title":"Molecular analysis of anoikis resistance in oral cavity squamous cell carcinoma","volume":"43","author":"Kupferman","year":"2007","journal-title":"Oral Oncol"},{"key":"key\n\t\t\t\t20170520230942_CIT0005","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/j.1600-0714.2011.01015.x","article-title":"Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma","volume":"40","author":"Tsai","year":"2011","journal-title":"J. Oral Pathol. Med"},{"key":"key\n\t\t\t\t20170520230942_CIT0006","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.bbrc.2009.05.048","article-title":"Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer","volume":"385","author":"Chen","year":"2009","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"key\n\t\t\t\t20170520230942_CIT0007","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1073\/pnas.0610117104","article-title":"Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma","volume":"104","author":"Prince","year":"2007","journal-title":"Proc. Natl Acad. Sci. U.S.A"},{"key":"key\n\t\t\t\t20170520230942_CIT0008","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1200\/JCO.2007.15.1613","article-title":"Cancer stem cells in head and neck squamous cell cancer","volume":"26","author":"Prince","year":"2008","journal-title":"J. Clin. Oncol"},{"key":"key\n\t\t\t\t20170520230942_CIT0009","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1002\/hed.21801","article-title":"Cancer stem cells in head and neck squamous cell carcinoma: A review of current knowledge and future applications","volume":"34","author":"Bhaijee","year":"2012","journal-title":"Head Neck"},{"key":"key\n\t\t\t\t20170520230942_CIT0010","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.oraloncology.2011.02.009","article-title":"Implications of understanding cancer stem cell (CSC) biology in head and neck squamous cell cancer","volume":"47","author":"Sayed","year":"2011","journal-title":"Oral Oncol"},{"key":"key\n\t\t\t\t20170520230942_CIT0011","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.critrevonc.2011.03.004","article-title":"Stem cells in squamous head and neck cancer","volume":"81","author":"Albers","year":"2012","journal-title":"Crit. Rev. Oncol. Hematol"},{"key":"key\n\t\t\t\t20170520230942_CIT0012","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nrm2636","article-title":"Epidermal homeostasis: a balancing act of stem cells in the skin","volume":"10","author":"Blanpain","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol"},{"key":"key\n\t\t\t\t20170520230942_CIT0013","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1634\/stemcells.2008-0611","article-title":"Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate","volume":"27","author":"Okubo","year":"2009","journal-title":"Stem Cells"},{"key":"key\n\t\t\t\t20170520230942_CIT0014","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/0092-8674(90)90115-U","article-title":"Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter","volume":"62","author":"Bailleul","year":"1990","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170520230942_CIT0015","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/S0960-9822(98)70203-9","article-title":"The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted","volume":"8","author":"Brown","year":"1998","journal-title":"Curr. Biol"},{"key":"key\n\t\t\t\t20170520230942_CIT0016","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1038\/nrc1095","article-title":"Stem-cell hierarchy in skin cancer","volume":"3","author":"Perez-Losada","year":"2003","journal-title":"Nat. Rev. Cancer"},{"key":"key\n\t\t\t\t20170520230942_CIT0017","doi-asserted-by":"crossref","first-page":"7425","DOI":"10.1073\/pnas.1012670108","article-title":"Defining the origins of Ras\/p53-mediated squamous cell carcinoma","volume":"108","author":"White","year":"2011","journal-title":"Proc. Natl Acad. Sci. U.S.A"},{"key":"key\n\t\t\t\t20170520230942_CIT0018","doi-asserted-by":"crossref","first-page":"7431","DOI":"10.1073\/pnas.1012720108","article-title":"Identifying the cellular origin of squamous skin tumors","volume":"108","author":"Lapouge","year":"2011","journal-title":"Proc. Natl Acad. Sci. U.S.A"},{"key":"key\n\t\t\t\t20170520230942_CIT0019","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1158\/1940-6207.CAPR-09-0136","article-title":"A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide","volume":"2","author":"Tang","year":"2009","journal-title":"Cancer Prev. Res. (Phila.)"},{"key":"key\n\t\t\t\t20170520230942_CIT0020","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1158\/1078-0432.CCR-0999-3","article-title":"Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice","volume":"10","author":"Tang","year":"2004","journal-title":"Clin. Cancer Res"},{"key":"key\n\t\t\t\t20170520230942_CIT0021","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1158\/1940-6207.CAPR-09-0058","article-title":"Chemical carcinogenesis models for evaluating molecular-targeted prevention and treatment of oral cancer","volume":"2","author":"Vitale-Cross","year":"2009","journal-title":"Cancer Prev. Res. (Phila.)"},{"key":"key\n\t\t\t\t20170520230942_CIT0022","doi-asserted-by":"crossref","first-page":"8551","DOI":"10.1073\/pnas.96.15.8551","article-title":"The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin","volume":"96","author":"Vasioukhin","year":"1999","journal-title":"Proc. Natl Acad. Sci. U.S.A"},{"key":"key\n\t\t\t\t20170520230942_CIT0023","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1073\/pnas.86.5.1563","article-title":"Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice","volume":"86","author":"Vassar","year":"1989","journal-title":"Proc. Natl Acad. Sci. U.S.A"},{"key":"key\n\t\t\t\t20170520230942_CIT0024","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1083\/jcb.201201041","article-title":"Tracing epithelial stem cells during development, homeostasis, and repair","volume":"197","author":"Van Keymeulen","year":"2012","journal-title":"J. Cell Biol"},{"key":"key\n\t\t\t\t20170520230942_CIT0025","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S1368-8375(98)00098-0","article-title":"Cell cycle proteins and the development of oral squamous cell carcinoma","volume":"35","author":"Schoelch","year":"1999","journal-title":"Oral Oncol"},{"key":"key\n\t\t\t\t20170520230942_CIT0026","first-page":"77","article-title":"The epidermal proliferative unit: the possible role of the central basal cell","volume":"7","author":"Potten","year":"1974","journal-title":"Cell Tissue Kinet"},{"key":"key\n\t\t\t\t20170520230942_CIT0027","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nature05574","article-title":"A single type of progenitor cell maintains normal epidermis","volume":"446","author":"Clayton","year":"2007","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170520230942_CIT0028","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.devcel.2009.12.016","article-title":"The ordered architecture of murine ear epidermis is maintained by progenitor cells with random fate","volume":"18","author":"Doupe","year":"2010","journal-title":"Dev. Cell"},{"key":"key\n\t\t\t\t20170520230942_CIT0029","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1093\/carcin\/9.12.2251","article-title":"Transformation of oral keratinocytes in vitro by 4-nitroquinoline N-oxide","volume":"9","author":"Crane","year":"1988","journal-title":"Carcinogenesis"},{"key":"key\n\t\t\t\t20170520230942_CIT0030","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1002\/ijc.2910140607","article-title":"Requirement for cell replication in the fixation and expression of the transformed state in mouse cells treated with 4-nitroquinoline-1-oxide","volume":"14","author":"Kakunaga","year":"1974","journal-title":"Int. J. Cancer"},{"key":"key\n\t\t\t\t20170520230942_CIT0031","first-page":"3672","article-title":"Excision of 4-nitroquinoline 1-oxide damage and transformed in mouse cells","volume":"37","author":"Ikenaga","year":"1977","journal-title":"Cancer Res"},{"key":"key\n\t\t\t\t20170520230942_CIT0032","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1093\/carcin\/10.7.1197","article-title":"The repair of identified large DNA adducts induced by 4-nitroquinoline-1-oxide in normal or xeroderma pigmentosum group A human fibroblasts, and the role of DNA polymerases alpha or delta","volume":"10","author":"Jones","year":"1989","journal-title":"Carcinogenesis"},{"key":"key\n\t\t\t\t20170520230942_CIT0033","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/nature07602","article-title":"Crypt stem cells as the cells-of-origin of intestinal cancer","volume":"457","author":"Barker","year":"2009","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170520230942_CIT0034","doi-asserted-by":"crossref","first-page":"7124","DOI":"10.1158\/1078-0432.CCR-09-0433","article-title":"Signaling in malignant astrocytomas: role of neural stem cells and its therapeutic implications","volume":"15","author":"Alcantara Llaguno","year":"2009","journal-title":"Clin. Cancer Res"},{"key":"key\n\t\t\t\t20170520230942_CIT0035","doi-asserted-by":"crossref","first-page":"e59","DOI":"10.1371\/journal.pbio.1000059","article-title":"Oncogenic Kras initiates leukemia in hematopoietic stem cells","volume":"7","author":"Sabnis","year":"2009","journal-title":"PLoS Biol"}],"container-title":["Carcinogenesis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/carcin\/article-pdf\/34\/5\/1158\/17293359\/bgt021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T13:18:11Z","timestamp":1503580691000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/carcin\/article-lookup\/doi\/10.1093\/carcin\/bgt021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,28]]},"references-count":35,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2013,1,28]]},"published-print":{"date-parts":[[2013,5]]}},"URL":"https:\/\/doi.org\/10.1093\/carcin\/bgt021","relation":{},"ISSN":["1460-2180","0143-3334"],"issn-type":[{"value":"1460-2180","type":"electronic"},{"value":"0143-3334","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1,28]]}}}