{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:10:21Z","timestamp":1790827821952,"version":"4.1.0"},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CARCIN"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1093\/carcin\/bgu049","type":"journal-article","created":{"date-parts":[[2014,2,22]],"date-time":"2014-02-22T20:34:18Z","timestamp":1393101258000},"page":"1951-1961","source":"Crossref","is-referenced-by-count":70,"title":["Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability"],"prefix":"10.1093","volume":"35","author":[{"given":"Rohann J.M.","family":"Correa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yudith Ramos","family":"Valdes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa M.","family":"Peart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena N.","family":"Fazio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique","family":"Bertrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"McGee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Pr\u00e9fontaine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Sugimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel E.","family":"DiMattia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor G.","family":"Shepherd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,2,22]]},"reference":[{"key":"2015103020132906000_35.9.1951.1","unstructured":"Howlader N . (eds) (2013). SEER Cancer Statistics Review, 1975\u20132010. National Cancer Institute, Bethesda, MD."},{"key":"2015103020132906000_35.9.1951.2","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2013.5"},{"key":"2015103020132906000_35.9.1951.3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105535"},{"key":"2015103020132906000_35.9.1951.4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103799"},{"key":"2015103020132906000_35.9.1951.5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1104390"},{"key":"2015103020132906000_35.9.1951.6","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-11-0170"},{"key":"2015103020132906000_35.9.1951.7","doi-asserted-by":"publisher","DOI":"10.1038\/nature10166"},{"key":"2015103020132906000_35.9.1951.8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2006.10.019"},{"key":"2015103020132906000_35.9.1951.9","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.10.104"},{"key":"2015103020132906000_35.9.1951.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.12.003"},{"key":"2015103020132906000_35.9.1951.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.06.022"},{"key":"2015103020132906000_35.9.1951.12","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E07-09-0858"},{"key":"2015103020132906000_35.9.1951.13","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2004.11.046"},{"key":"2015103020132906000_35.9.1951.14","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.25.3.1025-1040.2005"},{"key":"2015103020132906000_35.9.1951.15","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200801099"},{"key":"2015103020132906000_35.9.1951.16","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-0802"},{"key":"2015103020132906000_35.9.1951.17","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4402030"},{"key":"2015103020132906000_35.9.1951.18","doi-asserted-by":"publisher","DOI":"10.1172\/JCI28833"},{"key":"2015103020132906000_35.9.1951.19","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4402039"},{"key":"2015103020132906000_35.9.1951.20","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3432"},{"key":"2015103020132906000_35.9.1951.21","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgr241"},{"key":"2015103020132906000_35.9.1951.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2003.12.034"},{"key":"2015103020132906000_35.9.1951.23","doi-asserted-by":"crossref","unstructured":"Allen H.J. (1987) Isolation and morphologic characterization of human ovarian carcinoma cell clusters present in effusions. Exp. Cell Biol., 55, 194\u2013208.","DOI":"10.1159\/000163419"},{"key":"2015103020132906000_35.9.1951.24","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8274.CD-11-0010"},{"key":"2015103020132906000_35.9.1951.25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2008.11.032"},{"key":"2015103020132906000_35.9.1951.26","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.328"},{"key":"2015103020132906000_35.9.1951.27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2010.08.017"},{"key":"2015103020132906000_35.9.1951.28","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.06.009"},{"key":"2015103020132906000_35.9.1951.29","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000017"},{"key":"2015103020132906000_35.9.1951.30","doi-asserted-by":"publisher","DOI":"10.1126\/science.1106148"},{"key":"2015103020132906000_35.9.1951.31","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1205406"},{"key":"2015103020132906000_35.9.1951.32","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.01.028"},{"key":"2015103020132906000_35.9.1951.33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2008.07.076"},{"key":"2015103020132906000_35.9.1951.34","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.08.037"},{"key":"2015103020132906000_35.9.1951.35","doi-asserted-by":"publisher","DOI":"10.1007\/s10585-004-5768-5"},{"key":"2015103020132906000_35.9.1951.36","doi-asserted-by":"publisher","DOI":"10.1016\/0065-2571(84)90007-4"},{"key":"2015103020132906000_35.9.1951.37","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-5023"},{"key":"2015103020132906000_35.9.1951.38","doi-asserted-by":"crossref","unstructured":"Lu Z. (2008) The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells. J. Clin. Invest., 118, 3917\u20133929.","DOI":"10.1172\/JCI35512"},{"key":"2015103020132906000_35.9.1951.39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2006.06.001"},{"key":"2015103020132906000_35.9.1951.40","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3835(98)00198-0"},{"key":"2015103020132906000_35.9.1951.41","doi-asserted-by":"crossref","unstructured":"Tang M.K. (2010) c-Met overexpression contributes to the acquired apoptotic resistance of nonadherent ovarian cancer cells through a cross talk mediated by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase \u00bd. Neoplasia, 12, 128\u2013138.","DOI":"10.1593\/neo.91438"},{"key":"2015103020132906000_35.9.1951.42","doi-asserted-by":"crossref","unstructured":"Yoshida Y. (2008) Laminin-1-derived scrambled peptide AG73T disaggregates laminin-1-induced ovarian cancer cell spheroids and improves the efficacy of cisplatin. Int. J. Oncol., 32, 673\u2013681.","DOI":"10.3892\/ijo.32.3.673"},{"key":"2015103020132906000_35.9.1951.43","doi-asserted-by":"crossref","unstructured":"Xing H. (2007) Knock-down of P-glycoprotein reverses taxol resistance in ovarian cancer multicellular spheroids. Oncol. Rep., 17, 117\u2013122.","DOI":"10.3892\/or.17.1.117"},{"key":"2015103020132906000_35.9.1951.44","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-005-0677-9"},{"key":"2015103020132906000_35.9.1951.45","unstructured":"Green S.K. (2004) Antiadhesive antibodies targeting E-cadherin sensitize multicellular tumor spheroids to chemotherapy in vitro . Mol. Cancer Ther., 3, 149\u2013159."},{"key":"2015103020132906000_35.9.1951.46","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-5-200603070-00008"},{"key":"2015103020132906000_35.9.1951.47","doi-asserted-by":"crossref","unstructured":"Brice\u00f1o E. (2003) Therapy of glioblastoma multiforme improved by the antimutagenic chloroquine. Neurosurg. Focus, 14, e3.","DOI":"10.3171\/foc.2003.14.2.4"},{"key":"2015103020132906000_35.9.1951.48","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1118193109"},{"key":"2015103020132906000_35.9.1951.49","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20121344"},{"key":"2015103020132906000_35.9.1951.50","doi-asserted-by":"publisher","DOI":"10.1101\/gad.220897.113"}],"container-title":["Carcinogenesis"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/carcin\/article-pdf\/35\/9\/1951\/14133653\/bgu049.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T18:12:42Z","timestamp":1565201562000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/carcin\/article-lookup\/doi\/10.1093\/carcin\/bgu049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,22]]},"references-count":50,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2014,8,27]]},"published-print":{"date-parts":[[2014,9]]}},"alternative-id":["10.1093\/carcin\/bgu049"],"URL":"https:\/\/doi.org\/10.1093\/carcin\/bgu049","relation":{},"ISSN":["0143-3334","1460-2180"],"issn-type":[{"value":"0143-3334","type":"print"},{"value":"1460-2180","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,22]]}}}