{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:52:32Z","timestamp":1790545952848,"version":"4.1.0"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T00:00:00Z","timestamp":1692921600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Limited data are available regarding the association between psoriasis and common dental conditions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To investigate the risk of potential dental comorbidities in patients with psoriasis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a nationwide population-based cohort study to analyse the claims data of patients with psoriasis (n = 15 165) and age- and sex-matched controls (n = 75 825). The incidence risk of the following potential dental conditions was analysed: dental caries, pulp and periapical disease, periodontal disease, gingival changes and tooth loss.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>After adjusting for potential cofactors, the adjusted hazard ratios (aHRs) of dental caries [1.105; 95% confidence interval (CI) 1.078\u20131.132], pulp and periapical disease (1.07; 95% CI 1.044\u20131.096) and periodontal disease (1.108; 95% CI 1.088\u20131.129) were significantly higher than those in the control cohort (P &amp;lt; 0.001). However, among the subset of patients with psoriasis who received systemic antipsoriatic treatment (n = 4275), the aHR risk of all potential dental comorbidities was not significantly higher from that of the control cohort.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Patients with psoriasis have an increased risk of dental comorbidities, and systemic antipsoriatic treatment may help mitigate this increased risk.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ced\/llad286","type":"journal-article","created":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T19:12:00Z","timestamp":1692990720000},"page":"1347-1353","source":"Crossref","is-referenced-by-count":4,"title":["Increased dental comorbidities in patients with psoriasis: a nationwide population-based cohort study in Korea"],"prefix":"10.1093","volume":"48","author":[{"given":"Eun-Jung","family":"Kwak","sequence":"first","affiliation":[{"name":"National Dental Care Center for People with Special Needs, Seoul National University Dental Hospital , Seoul , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun Jin","family":"Choi","sequence":"additional","affiliation":[{"name":"Biomedical Research Institute, Korea University Guro Hospital , Seoul , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Na","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Guro Hospital, Korea University College of Medicine , Seoul , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ko Eun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Guro Hospital, Korea University College of Medicine , Seoul , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2456-7573","authenticated-orcid":false,"given":"Jiehyun","family":"Jeon","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Guro Hospital, Korea University College of Medicine , Seoul , Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8667-2814","authenticated-orcid":false,"given":"Yoo\u00a0Sang","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Guro Hospital, Korea University College of Medicine , Seoul , Republic of 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