{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:44:40Z","timestamp":1780472680058,"version":"3.54.1"},"reference-count":135,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T00:00:00Z","timestamp":1699056000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>COVID-19, the widely recognized and highly contagious respiratory tract infection, has had a substantial impact on the field of dermatology since its emergence in 2019. SARS-CoV-2, the causative virus of COVID-19, is classified as an RNA virus. Various skin-related symptoms have been reported in patients with COVID-19, most notably the distinctive purple\u2013red acral rash resembling chilblain lesions, commonly referred to as \u2018COVID toe\u2019; similarly, skin-related symptoms have been observed in connection with other RNA viruses.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To explore the relationship between RNA viruses and their associated vascular cutaneous manifestations vs. those observed in patients infected with SARS-CoV-2.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A systematic literature review was conducted using PubMed and medical subject heading terms related to RNA viruses and related skin manifestations.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In total, 3994 patients diagnosed with COVID-19 presenting with skin rashes were included. Chilblain-like lesions were most frequently observed (30.2%), followed by erythematous maculopapular\/morbilliform rashes (9.1%) and urticarial rashes (4.7%). Of 8362 patients diagnosed with RNA viruses, more than half of the skin findings reported were erythematous\/maculopapular\/morbilliform rashes (52.3%), followed by unspecified (11.3%) and purpuric rashes (10.6%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>When comparing RNA viral infections with COVID-19 infection, we observed similarities in the reported skin manifestations and their presumed pathways, with many implicated in the proinflammatory response. Owing to the wide range of cutaneous symptoms associated with RNA viruses and our currently limited understanding of the underlying mechanisms, additional research is warranted to investigate the pathology behind viral-induced skin lesions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ced\/llad377","type":"journal-article","created":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T06:34:31Z","timestamp":1699425271000},"page":"313-324","source":"Crossref","is-referenced-by-count":4,"title":["Vascular cutaneous manifestations of COVID-19 and RNA viral pathogens: a systematic review"],"prefix":"10.1093","volume":"49","author":[{"given":"Jamie L","family":"Karch","sequence":"first","affiliation":[{"name":"Department of Medicine, Geisel School of Medicine at Dartmouth , Hanover, NH , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2233-4557","authenticated-orcid":false,"given":"Chiamaka L","family":"Okorie","sequence":"additional","affiliation":[{"name":"Department of Medicine, Geisel School of Medicine at Dartmouth , Hanover, NH , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayra B C","family":"Maymone","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Warren Alpert Medical School, Brown University , Providence, RI , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Laughter","sequence":"additional","affiliation":[{"name":"Department of Dermatology, New York University , New York, NY , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelam\u00a0A","family":"Vashi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Boston University School of Medicine , Boston, MA , USA"},{"name":"Department of Dermatology, US Department of Veteran Affairs , Boston Health Care System, Boston, MA , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,4]]},"reference":[{"key":"2024032121315762000_llad377-B1","first-page":"e212","article-title":"Cutaneous manifestations in COVID-19: a first perspective","volume":"34","author":"Recalcati","year":"2020","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2024032121315762000_llad377-B2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/jocd.15477","article-title":"COVID-19 and cutaneous manifestations: a review of the published literature","volume":"22","author":"Martora","year":"2023","journal-title":"J\u00a0Cosmet Dermatol"},{"key":"2024032121315762000_llad377-B3","doi-asserted-by":"crossref","first-page":"e13926","DOI":"10.1111\/dth.13926","article-title":"Clinical and histopathological findings of cutaneous manifestations of COVID-19 patients","volume":"33","author":"Brand\u00e3o","year":"2020","journal-title":"Dermatol Ther"},{"key":"2024032121315762000_llad377-B4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/JCMA.0000000000000463","article-title":"Clinical manifestation and disease progression in COVID-19 infection","volume":"84","author":"Tsai","year":"2021","journal-title":"J Chin Med Assoc"},{"key":"2024032121315762000_llad377-B5","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3121\/cmr.2023.1598","article-title":"Cutaneous manifestation in COVID-19: a lesson over 2\u2005years into the pandemic","volume":"21","author":"Danarti","year":"2023","journal-title":"Clin Med Res"},{"key":"2024032121315762000_llad377-B6","doi-asserted-by":"crossref","DOI":"10.3390\/v14091972","article-title":"Pathobiology of cutaneous manifestations associated with COVID-19 and their management","volume":"14","author":"Masood","year":"2022","journal-title":"Viruses"},{"key":"2024032121315762000_llad377-B7","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1007\/s11239-021-02593-2","article-title":"A comprehensive review of vascular complications in COVID-19","volume":"53","author":"Acharya","year":"1234","journal-title":"J Thromb Thrombolysis"},{"key":"2024032121315762000_llad377-B8","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1111\/pde.14805","article-title":"\u201cCOVID toes\u201d: a meta-analysis of case and observational studies on clinical, histopathological, and laboratory findings","volume":"38","author":"Rocha","year":"2021","journal-title":"Pediatr Dermatol"},{"key":"2024032121315762000_llad377-B9","doi-asserted-by":"crossref","first-page":"175","DOI":"10.12809\/hkmj219690","article-title":"COVID toe in an adolescent boy: a case report","volume":"28","author":"Wong","year":"2022","journal-title":"Hong Kong Med J"},{"key":"2024032121315762000_llad377-B10","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jdcr.2022.10.037","article-title":"A case of late ulceration of infantile hemangioma in the setting of SARS-CoV2 infection","volume":"31","author":"Okorie","year":"2023","journal-title":"JAAD Case Rep"},{"key":"2024032121315762000_llad377-B11","doi-asserted-by":"crossref","first-page":"586407","DOI":"10.3389\/fphar.2020.586407","article-title":"Viral infections and cutaneous drug-related eruptions","volume":"11","author":"Anci","year":"2020","journal-title":"Front Pharmacol"},{"key":"2024032121315762000_llad377-B12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaad.2021.01.023","article-title":"The clinical spectrum of COVID-19-associated cutaneous manifestations: an Italian multicenter study of 200 adult patients","volume":"84","author":"Marzano","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"2024032121315762000_llad377-B13","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1139\/gen-2020-0124","article-title":"Epigenetic regulation of ACE2, the receptor of the SARS-CoV-2 virus","volume":"64","author":"Beacon","year":"2021","journal-title":"Genome"},{"key":"2024032121315762000_llad377-B14","doi-asserted-by":"crossref","first-page":"e00911","DOI":"10.1002\/prp2.911","article-title":"\u201cLONG COVID\u201d \u2013 a hypothesis for understanding the biological basis and pharmacological treatment strategy","volume":"10","author":"Jarrott","year":"2022","journal-title":"Pharmacol Res Perspect"},{"key":"2024032121315762000_llad377-B15","doi-asserted-by":"crossref","first-page":"13696","DOI":"10.1111\/dth.13696","article-title":"Cutaneous manifestations of COVID-19: a review of the published literature","volume":"33","author":"Elmas","year":"2020","journal-title":"Dermatol Ther"},{"key":"2024032121315762000_llad377-B16","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ijsu.2020.02.034","article-title":"World Health Organization declares global emergency: a review of the 2019 novel coronavirus (COVID-19)","volume":"76","author":"Sohrabi","year":"2020","journal-title":"Int J Surg"},{"key":"2024032121315762000_llad377-B17","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/j.jaad.2020.06.1016","article-title":"The spectrum of COVID-19-associated dermatologic manifestations: an international registry of 716 patients from 31 countries","volume":"83","author":"Freeman","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"2024032121315762000_llad377-B18","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/bjd.19163","article-title":"Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases","volume":"183","author":"Galv\u00e1n Casas","year":"2020","journal-title":"Br J Dermatol"},{"key":"2024032121315762000_llad377-B19","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.jaad.2020.05.059","article-title":"Cutaneous manifestations of COVID-19: a preliminary review","volume":"83","author":"Jia","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"2024032121315762000_llad377-B20","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1097\/QCO.0000000000000816","article-title":"Skin manifestations in patients with coronavirus disease 2019","volume":"35","author":"Bassetti","year":"2022","journal-title":"Curr Opin Infect Dis"},{"key":"2024032121315762000_llad377-B21","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.clindermatol.2022.01.002","article-title":"Pityriasis rosea, pityriasis rosea-like eruptions, and herpes zoster in the setting of COVID-19 and COVID-19 vaccination","volume":"40","author":"Drago","year":"2022","journal-title":"Clin Dermatol"},{"key":"2024032121315762000_llad377-B22","doi-asserted-by":"crossref","first-page":"65769","DOI":"10.1007\/s11356-021-15567-x","article-title":"Bioinformatic analyses suggest augmented interleukin-17 signaling as the mechanism of COVID-19-associated herpes zoster","volume":"28","author":"Yu","year":"2021","journal-title":"Environ Sci Pollut Res Int"},{"key":"2024032121315762000_llad377-B23","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.abd.2022.09.007","article-title":"Cutaneous manifestations of COVID-19 patients in a Hospital in S\u00e3o Paulo, Brazil, and global literature review","volume":"98","author":"da Cestari","year":"2023","journal-title":"An Bras Dermatol"},{"key":"2024032121315762000_llad377-B24","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.det.2021.05.012","article-title":"COVID-19 pediatric dermatology","volume":"39","author":"Neale","year":"2021","journal-title":"Dermatol Clin"},{"key":"2024032121315762000_llad377-B25","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.clindermatol.2020.12.016","article-title":"Pediatric COVID toes and fingers","volume":"39","author":"Koschitzky","year":"2021","journal-title":"Clin Dermatol"},{"key":"2024032121315762000_llad377-B26","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3947\/ic.2015.47.3.155","article-title":"Febrile illness with skin rashes","volume":"47","author":"Kang","year":"2015","journal-title":"Infect Chemother"},{"key":"2024032121315762000_llad377-B27","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/B978-0-323-44887-1.00027-4","volume-title":"Kendig\u2019s Disorders of the Respiratory Tract in Children","author":"Rao","year":"2019"},{"key":"2024032121315762000_llad377-B28","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1750-2659.2011.00197.x","article-title":"Rash, an uncommon but existing feature of H1N1 influenza among children","volume":"5","author":"Fretzayas","year":"2011","journal-title":"Influenza Other Respir Viruses"},{"key":"2024032121315762000_llad377-B29","doi-asserted-by":"crossref","DOI":"10.3346\/jkms.2012.27.12.1601","article-title":"Leukocytoclastic vasculitis associated with influenza A virus infection","volume":"27","author":"Lee","year":"2012","journal-title":"J Korean Med Sci"},{"key":"2024032121315762000_llad377-B30","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/irv.12296","article-title":"Case series of rash associated with influenza B in school children","volume":"9","author":"Skowronski","year":"2015","journal-title":"Influenza Other Respir Viruses"},{"key":"2024032121315762000_llad377-B31","first-page":"43","article-title":"Picornaviruses","volume":"343","author":"Tuthill","year":"2010","journal-title":"Curr Top Microbiol Immunol"},{"key":"2024032121315762000_llad377-B32","author":"Guerra"},{"issue":"384","key":"2024032121315762000_llad377-B33","article-title":"Oral and cutaneous manifestations of viral and bacterial infections: not only COVID-19 disease","volume":"39","author":"Drago","year":"2021","journal-title":"Clin Dermatol"},{"key":"2024032121315762000_llad377-B34","first-page":"274","article-title":"Acute localized exanthem due to Coxsackievirus A4","volume":"25","author":"Drago","year":"2017","journal-title":"Infez Med"},{"key":"2024032121315762000_llad377-B35","author":"Tariq"},{"key":"2024032121315762000_llad377-B36","doi-asserted-by":"crossref","first-page":"11383","DOI":"10.3390\/ijerph191811383","article-title":"Oral lesions associated with COVID-19 and the participation of the buccal cavity as a key player for establishment of immunity against SARS-CoV-2","volume":"19","author":"Gutierrez-Camacho","year":"2022","journal-title":"Int J Environ Res Public Health"},{"key":"2024032121315762000_llad377-B37","doi-asserted-by":"crossref","first-page":"338","DOI":"10.3390\/v9110338","article-title":"Structures and functions of the envelope glycoprotein in flavivirus infections","volume":"9","author":"Zhang","year":"2017","journal-title":"Viruses"},{"key":"2024032121315762000_llad377-B38","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.clindermatol.2021.06.003","article-title":"Clinicopathologic features among different viral epidemic outbreaks involving the skin","volume":"40","author":"Atzori","year":"2022","journal-title":"Clin Dermatol"},{"key":"2024032121315762000_llad377-B39","doi-asserted-by":"crossref","first-page":"e177","DOI":"10.1016\/j.jaad.2020.03.036","article-title":"COVID-19 can present with a rash and be mistaken for dengue","volume":"82","author":"Joob","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"2024032121315762000_llad377-B40","first-page":"63","volume-title":"Infections in Pregnancy: An Evidence-Based Approach","author":"Leonor","year":"2023"},{"key":"2024032121315762000_llad377-B41","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/ajd.13561","article-title":"Cutaneous manifestations and dermatological sequelae of Covid-19 infection compared to those from other viruses","volume":"62","author":"Sharma","year":"2021","journal-title":"Australas J Dermatol"},{"key":"2024032121315762000_llad377-B42","doi-asserted-by":"crossref","first-page":"380","DOI":"10.4269\/ajtmh.21-0884","article-title":"Chilblains associated with chronic chikungunya","volume":"106","author":"De Oliveira S\u00e1","year":"2022","journal-title":"Am J Trop Med Hyg"},{"key":"2024032121315762000_llad377-B43","first-page":"27588","article-title":"Post chikungunya fever and post COVID-19 bilateral pedal edema: a case report","volume":"14","author":"Pustake","year":"2022","journal-title":"Cureus"},{"key":"2024032121315762000_llad377-B44","first-page":"659","volume-title":"Geriatric Gastroenterology","author":"Pitchumoni","year":"2022"},{"key":"2024032121315762000_llad377-B45","author":"Bryan"},{"key":"2024032121315762000_llad377-B46","author":"Park"},{"key":"2024032121315762000_llad377-B47","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1309\/LMN1P2FRZ7BKZSCO","article-title":"Crimean-Congo hemorrhagic fever","volume":"46","author":"Shayan","year":"2015","journal-title":"Lab Med"},{"key":"2024032121315762000_llad377-B48","doi-asserted-by":"crossref","first-page":"408","DOI":"10.7883\/yoken.JJID.2018.005","article-title":"Cutaneous findings of Crimean-Congo hemorrhagic fever: a study of 269 cases","volume":"71","author":"Duygu","year":"2018","journal-title":"Jpn J Infect Dis"},{"key":"2024032121315762000_llad377-B49","doi-asserted-by":"crossref","first-page":"3667","DOI":"10.1111\/jocd.15258","article-title":"Cutaneous manifestations of Coronavirus Disease 2019","volume":"21","author":"Ghafoor","year":"2022","journal-title":"J Cosmet Dermatol"},{"key":"2024032121315762000_llad377-B50","doi-asserted-by":"crossref","first-page":"E13","DOI":"10.12788\/cutis.0397","article-title":"Retiform purpura on the buttocks in 6 critically ill COVID-19 patients","volume":"108","author":"Waqas","year":"2021","journal-title":"Cutis"},{"key":"2024032121315762000_llad377-B51","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1111\/pde.14699","article-title":"Henoch-Sch\u00f6nlein purpura: another COVID-19 complication","volume":"38","author":"Hasbani G","year":"2021","journal-title":"Pediatr Dermatol"},{"key":"2024032121315762000_llad377-B52","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.abd.2020.08.007","article-title":"Petechial lesions in a patient with COVID-19","volume":"96","author":"Fujimoto","year":"2021","journal-title":"An Bras Dermatol"},{"key":"2024032121315762000_llad377-B53","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/rheumatology\/keaa689","article-title":"Reactive arthritis and cutaneous vasculitis after SARS-CoV-2 infection","volume":"60","author":"Schenker","year":"2021","journal-title":"Rheumatology (Oxford)"},{"key":"2024032121315762000_llad377-B54","article-title":"Purpuric rash on the legs of a patient with coronavirus disease","volume":"5s3","author":"Silva","year":"2020","journal-title":"Rev Soc Bras Med Trop"},{"key":"2024032121315762000_llad377-B55","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1111\/ijlh.13346","article-title":"Immune thrombocytopenic purpura after COVID-19 infection","volume":"43","author":"Levraut","year":"2021","journal-title":"Int J Lab Hematol"},{"key":"2024032121315762000_llad377-B56","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/jmv.26221","article-title":"Oral erosions and petechiae during SARS-CoV-2 infection","volume":"93","author":"Ciccarese","year":"2021","journal-title":"J Med Virol"},{"key":"2024032121315762000_llad377-B57","doi-asserted-by":"crossref","first-page":"13798","DOI":"10.1111\/dth.13798","article-title":"A unilateral purpuric rash in a patient with COVID-19 infection","volume":"33","author":"Karaca","year":"2020","journal-title":"Dermatol Ther"},{"key":"2024032121315762000_llad377-B58","doi-asserted-by":"crossref","first-page":"13766","DOI":"10.1111\/dth.13766","article-title":"Schamberg-like purpuric eruptions and tonsillitis in mild COVID-19","volume":"33","author":"Wollina","year":"2020","journal-title":"Dermatol Ther"},{"key":"2024032121315762000_llad377-B59","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1056\/NEJMc2010472","article-title":"Immune thrombocytopenic purpura in a patient with Covid-19","volume":"382","author":"Zulfiqar","year":"2020","journal-title":"N Engl J Med"},{"key":"2024032121315762000_llad377-B60","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1111\/ijd.15180","article-title":"Skin manifestations in patients hospitalized with confirmed COVID-19 disease: a cross-sectional study in a tertiary hospital","volume":"59","author":"M\u00e9ndez Maestro","year":"2020","journal-title":"Int J Dermatol"},{"key":"2024032121315762000_llad377-B61","first-page":"278","article-title":"COVID-19 induced systemic thrombosis","volume":"155","author":"Fulgencio-Barbarin","year":"2020","journal-title":"Med Clin (Engl Ed)"},{"key":"2024032121315762000_llad377-B62","first-page":"399","article-title":"Morbilliform rashes in a patient with COVID-19 infection: a case report","volume":"59","author":"Ghimire","year":"2021","journal-title":"JNMA J Nepal Med Assoc"},{"key":"2024032121315762000_llad377-B63","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajem.2020.05.022","article-title":"COVID-19 infection with extensive thrombosis: a case of phlegmasia cerulea dolens","volume":"38","author":"Morales","year":"2020","journal-title":"Am J Emerg Med"},{"key":"2024032121315762000_llad377-B64","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.1111\/pde.14821","article-title":"BASCULE syndrome in a child with prior asymptomatic COVID-19 infection","volume":"38","author":"Berrebi","year":"2021","journal-title":"Pediatr Dermatol"},{"key":"2024032121315762000_llad377-B65","doi-asserted-by":"crossref","first-page":"600","DOI":"10.4103\/IJPM.IJPM_884_20","article-title":"COVID-19 acral lesions showing pauciinflammatory thrombotic microvasculopathy","volume":"64","author":"Calton","year":"2021","journal-title":"Indian J Pathol Microbiol"},{"key":"2024032121315762000_llad377-B66","doi-asserted-by":"crossref","first-page":"S183","DOI":"10.3122\/jabfm.2021.S1.200152","article-title":"Localized scarlatiniform rash of the ears and antecubital fossa in COVID-19","volume":"34","author":"Phamduy","year":"2021","journal-title":"J Am Board Fam Med"},{"key":"2024032121315762000_llad377-B67","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.clindermatol.2022.02.013","article-title":"Cutaneous leukocytoclastic vasculitis secondary to COVID-19 infection leading to extensive skin necrosis","volume":"40","author":"Capoferri","year":"2022","journal-title":"Clin Dermatol"},{"key":"2024032121315762000_llad377-B68","first-page":"99","article-title":"Reconstruction of COVID-19-related compartment \u00adsyndrome with massive soft tissue necrosis","volume":"33","author":"Bibbo","year":"2021","journal-title":"Wounds"},{"key":"2024032121315762000_llad377-B69","doi-asserted-by":"crossref","first-page":"2021046","DOI":"10.1590\/1984-0462\/2022\/40\/2021046","article-title":"Multisystem inflammatory syndrome in children: a case series","volume":"40","author":"Gaspar","year":"2022","journal-title":"Rev Paul Pediatr"},{"key":"2024032121315762000_llad377-B70","first-page":"5769","article-title":"Severe acute dried gangrene in COVID-19 infection: a case report","volume":"24","author":"Novara","year":"2020","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"2024032121315762000_llad377-B71","first-page":"873","article-title":"A typical case of multisystem inflammatory syndrome in a 10-year-old girl with COVID-19: a case report from Ethiopia","volume":"32","author":"Demissie","year":"2022","journal-title":"Ethiop J Health Sci"},{"key":"2024032121315762000_llad377-B72","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jdermsci.2020.04.011","article-title":"Cutaneous manifestations of COVID-19: report of three cases and a review of literature","volume":"98","author":"Sachdeva","year":"2020","journal-title":"J Dermatol Sci"},{"key":"2024032121315762000_llad377-B73","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1186\/s13052-022-01296-5","article-title":"Chilblain-like lesions onset during SARS-CoV-2 infection in a COVID-19-vaccinated adolescent: case report and review of literature","volume":"48","author":"Paparella","year":"2022","journal-title":"Ital J Pediatr"},{"key":"2024032121315762000_llad377-B74","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/pde.14210","article-title":"Chilblain-like lesions in children following suspected COVID-19 infection","volume":"37","author":"Colonna","year":"2020","journal-title":"Pediatr Dermatol"},{"key":"2024032121315762000_llad377-B75","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1007\/s10096-021-04305-3","article-title":"Prognosis of rash and chilblain-like lesions among outpatients with COVID-19: a large cohort study","volume":"40","author":"Mascitti","year":"2021","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2024032121315762000_llad377-B76","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/TME.0000000000000336","article-title":"A new rash differential: CoVID-19","volume":"43","author":"Gooch","year":"2021","journal-title":"Adv Emerg Nurs J"},{"key":"2024032121315762000_llad377-B77","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1111\/ijd.15632","article-title":"International registry of dermatological manifestations secondary to COVID-19 infection in 347 Hispanic patients from 25 countries","volume":"60","author":"Ocampo-Candiani","year":"2021","journal-title":"Int J Dermatol"},{"key":"2024032121315762000_llad377-B78","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1080\/20477724.2021.1901040","article-title":"Cutaneous manifestations in a series of 417 patients with SARS-CoV-2 infection: epidemiological and clinical correlates of chilblain like lesions","volume":"115","author":"Brancaccio","year":"2021","journal-title":"Pathog Glob Health"},{"key":"2024032121315762000_llad377-B79","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s11882-020-00986-6","article-title":"Cutaneous manifestations related to COVID-19 immune dysregulation in the pediatric age group","volume":"21","author":"Larenas-Linnemann","year":"2021","journal-title":"Curr Allergy Asthma Rep"},{"key":"2024032121315762000_llad377-B80","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1111\/ijd.15422","article-title":"Pseudo-chilblain lesions and COVID-19: a controversial relationship","volume":"60","author":"V\u00e1zquez-Osorio","year":"2021","journal-title":"Int J Dermatol"},{"key":"2024032121315762000_llad377-B81","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.annder.2020.12.002","article-title":"Cutaneous manifestations of COVID-19 in the Franche-Comt\u00e9 region of France: a monocentric study","volume":"148","author":"Jacquin-Porretaz","year":"2021","journal-title":"Ann Dermatol Venereol"},{"key":"2024032121315762000_llad377-B82","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s11239-020-02338-7","article-title":"Ecchymosis in critical coronavirus disease 2019 (COVID-19) patient in Tangerang, Indonesia: a case report","volume":"52","author":"Widysanto","year":"2021","journal-title":"J Thromb Thrombolysis"},{"key":"2024032121315762000_llad377-B83","doi-asserted-by":"crossref","first-page":"e237917","DOI":"10.1136\/bcr-2020-237917","article-title":"Chilblain-like lesions with prominent bullae in a patient with COVID-19","volume":"13","author":"Rubin","year":"2020","journal-title":"BMJ Case Rep"},{"key":"2024032121315762000_llad377-B84","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/pde.14409","article-title":"Suspected COVID-19-related reticulated purpura of the soles in an infant","volume":"38","author":"Andina","year":"2021","journal-title":"Pediatr Dermatol"},{"key":"2024032121315762000_llad377-B85","doi-asserted-by":"crossref","first-page":"e164","DOI":"10.1111\/jdv.16972","article-title":"Immunological and virological profile of children with chilblain-like lesions and SARS-CoV-2","volume":"35","author":"Fertitta","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2024032121315762000_llad377-B86","doi-asserted-by":"crossref","first-page":"e187","DOI":"10.1111\/jdv.16970","article-title":"SARS-CoV-2 spike protein is present in both endothelial and eccrine cells of a chilblain-like skin lesion","volume":"35","author":"Gambichler","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2024032121315762000_llad377-B87","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/pde.14215","article-title":"Chilblains in children in the setting of COVID-19 pandemic","volume":"37","author":"Andina","year":"2020","journal-title":"Pediatr Dermatol"},{"key":"2024032121315762000_llad377-B88","doi-asserted-by":"crossref","first-page":"13516","DOI":"10.1111\/dth.13516","article-title":"Chilblain-like lesions in pediatrics dermatological outpatients during the COVID-19 outbreak","volume":"33","author":"Garcia-Lara","year":"2020","journal-title":"Dermatol Ther"},{"key":"2024032121315762000_llad377-B89","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1111\/ijd.14937","article-title":"Chilblain-like lesions on feet and hands during the COVID-19 Pandemic","volume":"59","author":"Landa","year":"2020","journal-title":"Int J Dermatol"},{"key":"2024032121315762000_llad377-B90","doi-asserted-by":"crossref","first-page":"89896","DOI":"10.1371\/journal.pone.0089896","article-title":"Co-circulation of multiple hemorrhagic fever diseases with distinct clinical characteristics in Dandong, China","volume":"9","author":"Chen","year":"2014","journal-title":"PLOS ONE"},{"key":"2024032121315762000_llad377-B91","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.ijid.2007.09.010","article-title":"Clinical and laboratory features of Crimean-Congo hemorrhagic fever: predictors of fatality","volume":"12","author":"\u00c7evik","year":"2008","journal-title":"Int J Infect Dis"},{"key":"2024032121315762000_llad377-B92","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1186\/1471-2334-14-416","article-title":"Sequential determination of serum viral titers, virus-specific IgG antibodies, and TNF-\u03b1, IL-6, IL-10, and IFN-\u03b3 levels in patients with Crimean-Congo hemorrhagic fever","volume":"14","author":"Kaya","year":"2014","journal-title":"BMC Infect Dis"},{"key":"2024032121315762000_llad377-B93","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jinf.2005.05.003","article-title":"Crimean-Congo hemorrhagic fever in Eastern Turkey: clinical features, risk factors and efficacy of ribavirin therapy","volume":"52","author":"Ozkurt","year":"2006","journal-title":"J Infect"},{"key":"2024032121315762000_llad377-B94","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1089\/vbz.2015.1775","article-title":"Pancytopenia as the initial manifestation of brucellosis in children","volume":"15","author":"Karli","year":"2015","journal-title":"Vector Borne Zoonotic Dis"},{"issue":"Suppl. 4","key":"2024032121315762000_llad377-B95","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1093\/clinids\/11.Supplement_4.S794","article-title":"The clinical pathology of Crimean-Congo hemorrhagic fever","volume":"11","author":"Swanepoel","year":"1989","journal-title":"Rev Infect Dis"},{"key":"2024032121315762000_llad377-B96","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.ttbdis.2019.02.003","article-title":"Nucleocapsid protein-specific IgM antibody responses in the disease progression of severe fever with thrombocytopenia syndrome","volume":"10","author":"Wang","year":"2019","journal-title":"Ticks Tick Borne Dis"},{"key":"2024032121315762000_llad377-B97","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.jmii.2016.08.018","article-title":"Clinical features and dynamic ordinary laboratory tests differentiating dengue fever from other febrile illnesses in children","volume":"51","author":"Chen","year":"2018","journal-title":"J Microbiol Immunol Infect"},{"key":"2024032121315762000_llad377-B98","doi-asserted-by":"crossref","first-page":"330","DOI":"10.4269\/ajtmh.2010.09-0542","article-title":"The incidence, characteristics, and presentation of dengue virus infections during infancy","volume":"82","author":"Capeding","year":"2010","journal-title":"Am J Trop Med Hyg"},{"key":"2024032121315762000_llad377-B99","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4269\/ajtmh.1997.57.49","article-title":"The first reported outbreak of dengue hemorrhagic fever in Irian Jaya, Indonesia","volume":"57","author":"Richards","year":"1997","journal-title":"Am J Trop Med Hyg"},{"key":"2024032121315762000_llad377-B100","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1186\/s12879-016-2024-y","article-title":"A predictive model to differentiate dengue from other febrile illness","volume":"16","author":"Fern\u00e1ndez","year":"2016","journal-title":"BMC Infect Dis"},{"key":"2024032121315762000_llad377-B101","first-page":"1711","article-title":"Clinical presentations and laboratory findings in suspected cases of dengue virus","volume":"27","author":"Ageep","year":"2006","journal-title":"Saudi Med J"},{"key":"2024032121315762000_llad377-B102","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1111\/j.1365-4632.2007.03298.x","article-title":"Cutaneous manifestations of dengue viral infection in Punjab (north India)","volume":"46","author":"Thomas","year":"2007","journal-title":"Int J Dermatol"},{"key":"2024032121315762000_llad377-B103","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1002\/jmv.24525","article-title":"Characterization of dengue virus infections in a sample of patients suggests unique clinical, immunological, and virological profiles that impact on the diagnosis of dengue and dengue hemorrhagic fever","volume":"88","author":"Senaratne","year":"2016","journal-title":"J Med Virol"},{"key":"2024032121315762000_llad377-B104","first-page":"1","article-title":"Dengue fever in American military personnel in the Philippines: clinical observations on hospitalized patients during a 1984 epidemic","volume":"20","author":"Hayes","year":"1989","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"2024032121315762000_llad377-B105","doi-asserted-by":"crossref","first-page":"e1562","DOI":"10.1371\/journal.pntd.0001562","article-title":"Early clinical features of dengue virus infection in Nicaraguan children: a longitudinal analysis","volume":"6","author":"Biswas","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"2024032121315762000_llad377-B106","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/1423-0127-20-75","article-title":"Clinical and laboratory predictive markers for acute dengue infection","volume":"20","author":"Ho","year":"2013","journal-title":"J Biomed Sci"},{"key":"2024032121315762000_llad377-B107","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s12098-014-1523-3","article-title":"Clinical profile of dengue among children according to revised WHO classification: analysis of a 2012 outbreak from Southern India","volume":"82","author":"Sahana","year":"2015","journal-title":"Indian J Pediatr"},{"key":"2024032121315762000_llad377-B108","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/s10156-004-0343-1","article-title":"Relapse of idiopathic thrombocytopenic purpura caused by influenza A virus infection: a case report","volume":"10","author":"Kaneko","year":"2004","journal-title":"J Infect Chemother"},{"key":"2024032121315762000_llad377-B109","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1097\/INF.0b013e3181d40ced","article-title":"Petechial rash with pandemic influenza (H1N1) infection","volume":"29","author":"Shachor-Meyouhas","year":"2010","journal-title":"Pediatr Infect Dis J"},{"key":"2024032121315762000_llad377-B110","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.jcma.2011.08.010","article-title":"Acute immune thrombocytopenic purpura in an adolescent with 2009 novel H1N1 influenza A virus infection","volume":"74","author":"Lee","year":"2011","journal-title":"J Chin Med Assoc"},{"key":"2024032121315762000_llad377-B111","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1442-200X.1997.tb03587.x","article-title":"Agranulocytosis and thrombocytopenic purpura following measles infection in a living-related orthotopic liver transplantation recipient","volume":"39","author":"Arakawa","year":"1997","journal-title":"Acta Paediatr Jpn"},{"key":"2024032121315762000_llad377-B112","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.mehy.2017.12.028","article-title":"Subacute sclerosing panencephalitis and immune thrombocytopenia: more than a coincidence?","volume":"111","author":"Oncel","year":"2018","journal-title":"Med Hypotheses"},{"key":"2024032121315762000_llad377-B113","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0190-9622(08)81938-X","article-title":"Papular-purpuric \u2018gloves and socks\u2019 syndrome caused by measles virus","volume":"30","author":"P\u00e9rez-Ferriols","year":"1994","journal-title":"J Am Acad Dermatol"},{"key":"2024032121315762000_llad377-B114","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1177\/000992289303200606","article-title":"Respiratory syncytial virus as a cause of fever and petechiae in infants","volume":"32","author":"Coffin","year":"1993","journal-title":"Clin Pediatr (Phila)"},{"key":"2024032121315762000_llad377-B115","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1001\/archderm.1996.03890360117031","article-title":"Erythema elevatum diutinum and Crohn disease: a common pathogenic role for measles virus?","volume":"132","author":"Orteu","year":"1996","journal-title":"Arch Dermatol"},{"key":"2024032121315762000_llad377-B116","doi-asserted-by":"crossref","first-page":"e87391","DOI":"10.1371\/journal.pone.0087391","article-title":"Clinical features of coxsackievirus A4, B3 and B4 infections in children","volume":"9","author":"Lee","year":"2014","journal-title":"PLOS ONE"},{"key":"2024032121315762000_llad377-B117","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.jcv.2010.07.010","article-title":"Clinical features of echovirus 6 and 9 infections in children","volume":"49","author":"Lee","year":"2010","journal-title":"J Clin Virol"},{"key":"2024032121315762000_llad377-B118","doi-asserted-by":"crossref","first-page":"350","DOI":"10.2340\/00015555-2853","article-title":"Atypical hand, foot, and mouth disease caused by coxsackievirus A6 in Denmark: a diagnostic mimicker","volume":"98","author":"Horsten","year":"2018","journal-title":"Acta Derm Venereol"},{"key":"2024032121315762000_llad377-B119","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jcv.2018.11.003","article-title":"Severe atypical hand-foot-and-mouth disease in adults due to coxsackievirus A6: clinical presentation and phylogenesis of CV-A6 strains","volume":"110","author":"Broccolo","year":"2019","journal-title":"J Clin Virol"},{"key":"2024032121315762000_llad377-B120","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1007\/BF00320784","article-title":"Immune thrombocytopenic purpura associated with hepatitis A","volume":"52","author":"Ibarra","year":"1986","journal-title":"Blut"},{"issue":"11 Suppl. 2","key":"2024032121315762000_llad377-B121","first-page":"3","article-title":"Adult-onset Still\u2019s disease: is this truly a diagnosis of exclusion?","volume":"76","author":"Anderson","year":"2017","journal-title":"Hawaii J Med Public Health"},{"key":"2024032121315762000_llad377-B122","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1442-200x.2005.02046.x","article-title":"Clinical spectrum in hospitalized children with echovirus type 13 infection","volume":"47","author":"Kobayashi","year":"2005","journal-title":"Pediatr Int"},{"key":"2024032121315762000_llad377-B123","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1111\/j.1346-8138.2007.00384.x","article-title":"Case of adult T-cell leukemia\/lymphoma manifesting marked purpura","volume":"34","author":"Okada","year":"2007","journal-title":"J Dermatol"},{"key":"2024032121315762000_llad377-B124","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/00005792-200001000-00005","article-title":"Extrahepatic manifestations associated with hepatitis C virus infection. A prospective multicenter study of 321 patients","volume":"79","author":"Cacoub","year":"2000","journal-title":"Medicine"},{"key":"2024032121315762000_llad377-B125","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1590\/S0036-46652006000400006","article-title":"Clinical and epidemiological aspects of HTLV-II infection in S\u00e3o Paulo, Brazil: presence of tropical spastic paraparesis\/HTLV-associated myelopathy (TSP\/HAM) simile diagnosis in HIV-1-co-infected subjects","volume":"48","author":"Posada-Vergara","year":"2006","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"2024032121315762000_llad377-B126","doi-asserted-by":"crossref","first-page":"e106205","DOI":"10.1371\/journal.pone.0106205","article-title":"Large vessel adventitial vasculitis characterizes patients with critical lower limb ischemia with as compared to without human immunodeficiency virus infection","volume":"9","author":"Brand","year":"2014","journal-title":"PLOS ONE"},{"key":"2024032121315762000_llad377-B127","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s00296-007-0492-5","article-title":"Henoch-Sch\u00f6nlein purpura in a patient with human immunodeficiency virus infection","volume":"28","author":"Sugimoto","year":"2008","journal-title":"Rheumatol Int"},{"key":"2024032121315762000_llad377-B128","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.medmal.2013.12.001","article-title":"Biphasic hepatitis A with severe cholestasis and thrombocytopenic purpura in an HIV-1-infected male patient","volume":"44","author":"Bani-Sadr","year":"2014","journal-title":"Med Mal Infect"},{"key":"2024032121315762000_llad377-B129","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.1016\/j.ijid.2008.05.1225","article-title":"Henoch-Sch\u00f6\u200cnlein purpura and thrombocytopenia after planned antiretroviral treatment interruption in a Thai girl with HIV infection","volume":"13","author":"Bunupuradah","year":"2009","journal-title":"Int J Infect Dis"},{"key":"2024032121315762000_llad377-B130","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1542\/peds.90.5.688","article-title":"Delayed recognition of human immunodeficiency virus infection in preadolescent children","volume":"90","author":"Persaud","year":"1992","journal-title":"Pediatrics"},{"key":"2024032121315762000_llad377-B131","doi-asserted-by":"crossref","first-page":"358","DOI":"10.47102\/annals-acadmedsg.V42N7p358","article-title":"Henoch-Sch\u00f6nlein purpura associated with adult human immunodeficiency virus infection: case report and review of the literature","volume":"42","author":"Zaid","year":"2013","journal-title":"Ann Acad Med Singap"},{"key":"2024032121315762000_llad377-B132","doi-asserted-by":"crossref","first-page":"159","DOI":"10.7883\/yoken.JJID.2014.195","article-title":"Epidemiological characteristics of rubella and congenital rubella syndrome in the 2012-2013 epidemics in Tokyo, Japan","volume":"68","author":"Sugishita","year":"2015","journal-title":"Jpn J Infect Dis"},{"key":"2024032121315762000_llad377-B133","first-page":"311","article-title":"A study on chikungunya outbreak during 2007 in Kerala, south India","volume":"129","author":"Kannan","year":"2009","journal-title":"Indian J Med Res"},{"key":"2024032121315762000_llad377-B134","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1001\/archopht.1967.00980020436004","article-title":"Clinical manifestations of postnatal and congenital rubella","volume":"77","author":"Cooper","year":"1967","journal-title":"Arch Ophthalmol"},{"key":"2024032121315762000_llad377-B135","doi-asserted-by":"crossref","DOI":"10.1177\/1076029618821184","article-title":"Zika and chikungunya virus and risk for venous thromboembolism","volume":"25","author":"Ramacciotti","year":"2019","journal-title":"Clin Appl Thromb Hemost"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ced\/advance-article-pdf\/doi\/10.1093\/ced\/llad377\/56517986\/llad377.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/49\/4\/313\/57052497\/llad377.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/49\/4\/313\/57052497\/llad377.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T21:33:34Z","timestamp":1711056814000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/49\/4\/313\/7344685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,4]]},"references-count":135,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,11,4]]},"published-print":{"date-parts":[[2024,3,21]]}},"URL":"https:\/\/doi.org\/10.1093\/ced\/llad377","relation":{},"ISSN":["0307-6938","1365-2230"],"issn-type":[{"value":"0307-6938","type":"print"},{"value":"1365-2230","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,4]]},"published":{"date-parts":[[2023,11,4]]}}}