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The patient was diagnosed clinically with inflammatory linear verrucous epidermal naevus. Deep next-generation sequencing of the lesion showed a somatic mutation in CARD14. The patient was treated with secukinumab and experienced significant improvement.<\/jats:p>","DOI":"10.1093\/ced\/llae047","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T02:31:35Z","timestamp":1708309895000},"page":"631-633","source":"Crossref","is-referenced-by-count":10,"title":["Effect of secukinumab on inflammatory linear verrucous epidermal naevus with a somatic mutation in\n                    <i>CARD14<\/i>"],"prefix":"10.1093","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2493-9031","authenticated-orcid":false,"given":"Xinrong","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Dermatology, Beijing Children\u2019s Hospital, Capital Medical University, National Center for Children\u2019s Health , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoyang","family":"Miao","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Beijing Children\u2019s Hospital, 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