{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T21:58:42Z","timestamp":1774648722624,"version":"3.50.1"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:00:00Z","timestamp":1710806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007190","name":"Unilever","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007190","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Erasmus Medical Center and Erasmus University"},{"DOI":"10.13039\/501100001826","name":"Netherlands Organisation for Health Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Research Institute for Diseases in the Elderly"},{"DOI":"10.13039\/501100005992","name":"Ministry of Education, Culture and Science","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005992","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Ministry for Health, Welfare and Sports"},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Municipality of Rotterdam"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Itch, common in dermatological conditions, is often accompanied by psychological distress and reduced quality of life. However, research on the prevalence and associated factors of itch with skin conditions in general populations is limited.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>This cross-sectional study aimed to determine the lifetime prevalence of itch with skin conditions and to identify its associated factors in individuals aged &amp;gt; 50\u2005years.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Participants from the Rotterdam Study, a population-based cohort, were interviewed to assess whether they had ever had an itchy skin condition, defining lifetime itch with skin conditions. Over 20 demographic, lifestyle, dermatological and nondermatological factors were recorded. Multivariable logistic regression analysis explored associations between these factors and itch with skin conditions, reported as odds ratios (ORs) with 95% confidence intervals (CIs).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>In total, 5246 eligible participants were included (age range 51\u2013100\u2005years, median age 67; 56.0% women). The results revealed a\u00a0\u00adlifetime prevalence of 33.7% for itch with skin conditions. Factors significantly associated with itch were female sex (OR 1.26, 95% CI 1.11\u20131.43), body mass index (1.02, 1.01\u20131.03), self-reported atopic dermatitis (4.29, 3.74\u20134.92), presence of atopic dermatitis (1.97, 1.60\u20132.43), self-\u00adreported psoriasis (2.31, 1.77\u20133.01), presence of psoriasis (2.11, 1.55\u20132.87), self-reported dry skin (1.95, 1.73\u20132.20), self-reported asthma (1.40, 1.08\u20131.83), renal impairment (1.45, 1.17\u20131.79), and clinically relevant depressive (1.85, 1.52\u20132.25) and anxiety symptoms (1.36, 1.11\u20131.66).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This study reveals a substantial one-third lifetime prevalence of itch with skin conditions in individuals aged &amp;gt; 50\u2005years. Significant associations with diverse lifestyle, demographic, dermatological and, intriguingly, nondermatological factors, including renal impairment, imply additional contributors to induction or persistence of itch in individuals with skin conditions.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ced\/llae077","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T13:35:54Z","timestamp":1710855354000},"page":"1036-1043","source":"Crossref","is-referenced-by-count":10,"title":["Lifetime prevalence and associated factors of itch with skin conditions: atopic dermatitis, psoriasis and dry skin in individuals aged &amp;gt; 50\u2005years"],"prefix":"10.1093","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2350-9526","authenticated-orcid":false,"given":"Juliette F","family":"Bollemeijer","sequence":"first","affiliation":[{"name":"Department of Dermatology, Erasmus University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang J","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Erasmus University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra M","family":"van der Meer","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Erasmus University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M Kamran","family":"Ikram","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands"},{"name":"Department of Neurology, Erasmus University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5976-6519","authenticated-orcid":false,"given":"Maryam","family":"Kavousi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8713-1481","authenticated-orcid":false,"given":"Willem P","family":"Brouwer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7517-197X","authenticated-orcid":false,"given":"Annemarie I","family":"Luik","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands"},{"name":"Trimbos Institute, the Netherlands Institute of Mental Health and Addiction , Utrecht , the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Layal","family":"Chaker","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanning","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9866-3221","authenticated-orcid":false,"given":"David A","family":"Gunn","sequence":"additional","affiliation":[{"name":"Unilever Research and Development, Colworth Science Park , Sharnbrook , UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9940-2875","authenticated-orcid":false,"given":"Tamar E 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