{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T23:47:02Z","timestamp":1784072822505,"version":"3.55.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T00:00:00Z","timestamp":1722038400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100000725","name":"the","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007275","name":"MOST","doi-asserted-by":"publisher","award":["111-2314-B-A49A-508-MY3"],"award-info":[{"award-number":["111-2314-B-A49A-508-MY3"]}],"id":[{"id":"10.13039\/501100007275","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V113C-004"],"award-info":[{"award-number":["V113C-004"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Air pollution is associated with several inflammatory skin disorders. However, the association between air quality and rosacea remains unclear.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To investigate the association between the Air Quality Index (AQI) and incidence of rosacea.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In total, 21 709 479 participants without rosacea before 2008 were recruited from the Taiwan National Health Insurance Research Database. The long-term average AQI value for each participant was acquired from the Taiwan Air Quality Monitoring System Network and calculated from 1 January 2008 until the diagnosis of rosacea, withdrawal from the National Health Insurance programme, or 31 December 2018.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We observed a significant association between AQI and the incidence of rosacea, with each unit elevation in the AQI increasing the risk of rosacea by 5%. We then categorized participants equally into four groups by quantiles (Q) of AQI values, with mean AQI values of: Q1, 69.0 (SD 6.4); Q2, 79.0 (SD 2.3); Q3, 89.9 (SD 3.6); and Q4, 103.9 (SD 6.8). Compared with the Q1 group, the Q2, Q3 and Q4 cohorts exhibited 1.82-fold, 4.48-fold and 7.22-fold increased risk of rosacea, respectively. Additionally, exposure to particulate matter (PM)2.5 (airborne particulate matter with a diameter \u2264 2.5 \u03bcm), sulfur dioxide (SO2) and carbon monoxide increased the risk of rosacea, whereas exposure to PM10 (airborne PM with a diameter \u2264 10 \u03bcm) was associated with a lower risk.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This study supported a significant dose\u2013response relationship between AQI and the incidence of rosacea.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ced\/llae291","type":"journal-article","created":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T18:59:55Z","timestamp":1722020395000},"page":"69-76","source":"Crossref","is-referenced-by-count":6,"title":["Association between Air Quality Index and the risk of rosacea: a nationwide population-based cohort study"],"prefix":"10.1093","volume":"50","author":[{"given":"Sheng-Hsiang","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Dermatology, Taipei Veterans General Hospital , Taipei ,","place":["Taiwan"]},{"name":"Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University , Taipei ,","place":["Taiwan"]},{"name":"Institute of Public Health and Department of Public Health, National Yang Ming Chiao Tung University , Taipei ,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Ying","family":"Wu","sequence":"additional","affiliation":[{"name":"Health Innovation Center, National Yang Ming Chiao Tung University , Taipei ,","place":["Taiwan"]},{"name":"Institute of Biomedical Informatics, National Yang Ming Chiao Tung University , Taipei ,","place":["Taiwan"]},{"name":"Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University , Taipei ,","place":["Taiwan"]},{"name":"Division of 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