{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T01:20:30Z","timestamp":1778894430205,"version":"3.51.4"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:00:00Z","timestamp":1723075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"University of Melbourne Research Scholarship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,27]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Clinician-reported outcome measures (ClinROMs) are an important part of disease assessment in daily practice and clinical trials. There is a broad disagreement on the most appropriate ClinROM for a comprehensive assessment of alopecia areata (AA) severity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To identify the currently available ClinROMs for AA through a systematic literature search, address their practical strengths and weaknesses, and identify the road ahead for future research.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A search was conducted of the published, peer-reviewed literature via PubMed (MEDLINE) and Embase (via Ovid) databases. Articles published in English within the past 23\u2005years (post-2000) that objectively measured AA severity were included. We did not select scoring systems that were solely based on patient-reported outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The literature search identified 1376 articles, of which 27 were chosen for full-text review. Based on our eligibility criteria, 14 articles were identified, describing 16 different ClinROMs. Five ClinROMs solely measured scalp hair loss [Severity of Alopecia Tool (SALT), SALT II, Alopecia Density and Extent (ALODEX), pediatric SALT (pSALT) and Alopecia Areata Investigator Global Assessment Scale (AA-IGA)]. Three trichoscopy-based ClinROMs assessed disease activity [Alopecia Areata Progression Index (AAPI), Alopecia Areata Predictive Score (AAPS) and the coudability hair score]. Six ClinROMs exclusively assessed nonscalp areas [Brigham Eyebrow Tool for Alopecia Areata (BETA), Brigham Eyelash Tool for Alopecia Areata (BELA), Alopecia Barbae Severity (ALBAS), ClinRO Measure for Eyebrow Hair Loss\u2122, ClinRO Measure for Eyelash Hair Loss\u2122 and ClinRO Measure for Nail Appearance\u2122]. Two ClinROMs assessed both scalp and nonscalp domains [Alopecia Areata Severity Index (AASI) and Alopecia Areata Scale (AASc)]. The practical strengths and weaknesses of each assessment tool are described.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Various practical limitations associated with their established tools have impeded the universal implementation in routine clinical practice. There is a significant need for a composite clinical severity scoring system to capture all the key severity identifiers beyond the involvement of the scalp.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ced\/llae320","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:04:14Z","timestamp":1723075454000},"page":"267-278","source":"Crossref","is-referenced-by-count":9,"title":["Assessment of clinician-reported outcome measures for alopecia areata: a systematic scoping review"],"prefix":"10.1093","volume":"50","author":[{"given":"Emadodin","family":"Darchini-Maragheh","sequence":"first","affiliation":[{"name":"Department of Medicine, The University of Melbourne , VIC ,","place":["Australia"]},{"name":"Sinclair Dermatology , Melbourne, VIC ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5318-6553","authenticated-orcid":false,"given":"Anthony","family":"Moussa","sequence":"additional","affiliation":[{"name":"Sinclair Dermatology , Melbourne, VIC ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huw","family":"Rees","sequence":"additional","affiliation":[{"name":"Sinclair Dermatology , Melbourne, VIC ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie","family":"Jones","sequence":"additional","affiliation":[{"name":"Sinclair Dermatology , Melbourne, VIC ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laita","family":"Bokhari","sequence":"additional","affiliation":[{"name":"Sinclair Dermatology , Melbourne, VIC ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodney","family":"Sinclair","sequence":"additional","affiliation":[{"name":"Department of Medicine, The University of Melbourne , VIC ,","place":["Australia"]},{"name":"Sinclair Dermatology , Melbourne, VIC ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,8,8]]},"reference":[{"key":"2025012715570260200_llae320-B1","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.111921","volume-title":"An updated in the management of alopecia areata. 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