{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T19:44:15Z","timestamp":1791229455794,"version":"4.1.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T00:00:00Z","timestamp":1723852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Lichen planopilaris (LPP) and its variants, mainly frontal fibrosing alopecia (FFA), affect the hair follicles, causing cicatricial alopecia. The condition has a significant negative impact on self-confidence and quality of life (QoL). This systematic review investigates the psychoemotional impact of LPP and its variants using the PRISMA guidelines. The review revealed that LPP and FFA cause significant psychological distress and impaired QoL. Higher LPP disease activity and severity were associated with higher depression and anxiety scores, lower quality-of-life scores, and higher scores of role limitations (physical and emotional). Additionally, facial lesions in patients with FFA, especially with eyebrow involvement, can be very distressing, leading to impaired self-esteem and reduced QoL. This negative impact of active and severe LPP and FFA on patients\u2019 QoL and self-esteem causes psychiatric conditions including anxiety and depression. Therefore, an early diagnosis must be encouraged in these patients.<\/jats:p>","DOI":"10.1093\/ced\/llae339","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T22:55:08Z","timestamp":1723762508000},"page":"146-149","source":"Crossref","is-referenced-by-count":5,"title":["Quality-of-life assessment and the impact of early diagnosis and treatment in lichen planopilaris: a systematic review"],"prefix":"10.1093","volume":"50","author":[{"given":"Awatef","family":"Kelati","sequence":"first","affiliation":[{"name":"Dermatology Department, University Hospital Cheikh Khalifa, and the University Hospital Mohammed VI Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS) , Casablanca ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6358-9068","authenticated-orcid":false,"given":"Mohammad","family":"Jafferany","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Central Michigan University\/CMU Medical Education Partners , Saginaw, MI ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,8,17]]},"reference":[{"key":"2024122223544716800_llae339-B1","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/bjd.13259","article-title":"The role of beliefs: lessons from a pilot study on illness perception, psychological distress and quality of life in patients with primary cicatricial alopecia","volume":"172","author":"Chiang","year":"2015","journal-title":"Br J Dermatol"},{"key":"2024122223544716800_llae339-B2","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ijwd.2017.07.001","article-title":"Quality of life in mild and severe alopecia areata patients","volume":"4","author":"Abedini","year":"2018","journal-title":"Int J Womens Dermatol"},{"key":"2024122223544716800_llae339-B3","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s40257-013-0021-0","article-title":"Impact of dermatologic adverse events on quality of life in 283 cancer patients: a questionnaire study in a dermatology referral clinic","volume":"14","author":"Rosen","year":"2013","journal-title":"Am J Clin Dermatol"},{"key":"2024122223544716800_llae339-B4","doi-asserted-by":"crossref","first-page":"e288\u201390","DOI":"10.1111\/jdv.17798","article-title":"Quality-of-life impairment is not related to disease activity in lichen planopilaris and frontal fibrosing alopecia. Results of a preliminary cross-sectional study","volume":"36","author":"Doche","year":"2022","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2024122223544716800_llae339-B5","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.ijwd.2020.09.005","article-title":"Quality of life and mental health status in patients with lichen planopilaris based on Dermatology Life Quality Index and General Health Questionnaire-28 questionnaires","volume":"6","author":"Nasimi","year":"2020","journal-title":"Int J Womens Dermatol"},{"key":"2024122223544716800_llae339-B6","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1159\/000499135","article-title":"Compared to controls, individuals with lichen planopilaris have more depression, a lower self-esteem, and a lower quality of life","volume":"78","author":"Alirezaei","year":"2019","journal-title":"Neuropsychobiology"},{"key":"2024122223544716800_llae339-B7","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1001\/jamadermatol.2017.6330","article-title":"Health-related quality of life in patients with frontal fibrosing alopecia","volume":"154","author":"Saceda-Corralo","year":"2018","journal-title":"JAMA Dermatol"},{"key":"2024122223544716800_llae339-B8","doi-asserted-by":"crossref","first-page":"824","DOI":"10.3390\/jcm12030824","article-title":"Frontal Fibrosing Alopecia Quality of Life Index: a validated disease-specific questionnaire involving women","volume":"12","author":"Porri\u00f1o-Bustamante","year":"2023","journal-title":"J Clin Med"},{"key":"2024122223544716800_llae339-B9","doi-asserted-by":"crossref","first-page":"6169","DOI":"10.1111\/jocd.15183","article-title":"Assessment of health-related quality of life in patients with frontal fibrosing alopecia","volume":"21","author":"Varghaei","year":"2022","journal-title":"J Cosmet Dermatol"},{"key":"2024122223544716800_llae339-B10","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000495117","article-title":"Early diagnosis and prompt treatment improves quality of life in patients with frontal fibrosing alopecia","volume":"5","author":"Dhurat","year":"2019","journal-title":"Skin Appendage Disord"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ced\/advance-article-pdf\/doi\/10.1093\/ced\/llae339\/59762186\/llae339.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/50\/1\/146\/59762186\/llae339.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/50\/1\/146\/59762186\/llae339.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,22]],"date-time":"2024-12-22T23:54:54Z","timestamp":1734911694000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/50\/1\/146\/7734854"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,17]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,8,17]]},"published-print":{"date-parts":[[2024,12,23]]}},"URL":"https:\/\/doi.org\/10.1093\/ced\/llae339","relation":{},"ISSN":["0307-6938","1365-2230"],"issn-type":[{"value":"0307-6938","type":"print"},{"value":"1365-2230","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,1]]},"published":{"date-parts":[[2024,8,17]]}}}