{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:20:42Z","timestamp":1745554842935,"version":"3.40.4"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T00:00:00Z","timestamp":1740441600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82103717","82272288"],"award-info":[{"award-number":["82103717","82272288"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Shandong Provincial Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Clinical Research Project of Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine","award":["JYHX2024008"],"award-info":[{"award-number":["JYHX2024008"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Despite ongoing advancements in medical aesthetics, there remains a lack of consensus regarding a standardized postoperative care protocol following laser treatment for skin pigmentation disorders.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To evaluate the influence of postoperative facial cleansing practices on the efficacy and safety of laser therapy among patients diagnosed with pigmentary skin diseases.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Thirty patients diagnosed with pigmented lesions (freckles and\/or solar lentigines) were randomly allocated to two distinct groups. Following treatment with a 755-nm alexandrite laser, patients in one group were instructed to perform water cleansing, while the other followed a water-avoidance care protocol. Follow-up visits were conducted on days 1, 3, 7 and 14 after treatment and 3\u2005months postoperatively. These visits included taking standardized photographs, performing VISIA imaging assessments, collecting patient satisfaction questionnaires and recording any potential adverse events.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>No serious complications were reported in either group. Most patients demonstrated improvement in their lesions to varying degrees with a single treatment session. No statistically significant differences were identified between the two groups in terms of postoperative visual analogue scale scores (P = 0.17). VISIA analysis revealed a significant decrease in brown spot count in both groups at the 3-month follow-up compared with baseline, with no significant differences between groups (P = 0.99). The average score of patients\u2019 satisfaction in the water-cleansing group was significantly higher than that in the water-avoidance group (P = 0.039).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Our studies have demonstrated that laser treatment of epidermal hyperpigmentation disorders without strict water avoidance can have equally good results with no added adverse effects.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ced\/llae525","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T14:06:45Z","timestamp":1740492405000},"page":"960-967","source":"Crossref","is-referenced-by-count":0,"title":["What is the optimal timing for advising patients to wash the treatment areas after laser therapy? A prospective, assessor-blinded, randomized controlled trial"],"prefix":"10.1093","volume":"50","author":[{"given":"Yue","family":"Han","sequence":"first","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]},{"name":"Department of Plastic and Reconstructive Surgery, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6852-1007","authenticated-orcid":false,"given":"Rui","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]},{"name":"Department of Plastic and Reconstructive Surgery, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lanjun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiafang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenxin","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]},{"name":"Department of Plastic and Reconstructive Surgery, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linting","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]},{"name":"Department of Plastic and Reconstructive Surgery, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]},{"name":"Department of Plastic and Reconstructive Surgery, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Shang","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxi","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Laser and Aesthetic Medicine, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]},{"name":"Department of Plastic and Reconstructive Surgery, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,2,25]]},"reference":[{"key":"2025042411074724400_llae525-B1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.jaad.2022.01.051","article-title":"Disorders of hyperpigmentation. 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