{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T13:12:55Z","timestamp":1771506775458,"version":"3.50.1"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T00:00:00Z","timestamp":1733443200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,23]]},"abstract":"<jats:p>We report a case of psoriasis-like eruptions after topical imiquimod. We demonstrated that mast cells are significantly associated with imiquimod-induced psoriasis, supporting previous reports. Based on the differences in mast cell counts, it can be inferred that the pathomechanism of imiquimod-induced psoriasis is distinct from psoriasis.<\/jats:p>","DOI":"10.1093\/ced\/llae527","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T22:45:51Z","timestamp":1733870751000},"page":"1221-1224","source":"Crossref","is-referenced-by-count":2,"title":["Widespread imiquimod-induced psoriasis-like eruption: case report and analysis of mast cell infiltration"],"prefix":"10.1093","volume":"50","author":[{"given":"Tatsuya","family":"Katsumi","sequence":"first","affiliation":[{"name":"Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences , Niigata ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6998-531X","authenticated-orcid":false,"given":"Ryota","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences , Niigata ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Takei","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences , Niigata ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manon","family":"Okamura","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences , Niigata ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuka","family":"Tsutsui","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences , Niigata ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9944-2228","authenticated-orcid":false,"given":"Osamu","family":"Ansai","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences , Niigata ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akito","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences , Niigata ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Matsui","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Niigata Cancer Center Hospital , Niigata ,","place":["Japan"]},{"name":"Department of Dermatology, Faculty of Medicine, Academic Assembly, University of Toyama , Toyama ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Takenouchi","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Niigata Cancer Center Hospital , Niigata ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riichiro","family":"Abe","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences , Niigata ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,12,6]]},"reference":[{"key":"2025052303173014900_llae527-B1","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/S0140-6736(20)32549-6","article-title":"Psoriasis","volume":"397","author":"Griffiths","year":"2021","journal-title":"Lancet"},{"key":"2025052303173014900_llae527-B2","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/s12964-023-01075-7","article-title":"IL-33-mediated activation of mast cells is involved in the progression of imiquimod-induced psoriasis-like dermatitis","volume":"21","author":"Zhou","year":"2023","journal-title":"Cell Commun Signal"},{"key":"2025052303173014900_llae527-B3","doi-asserted-by":"crossref","first-page":"279","DOI":"10.2340\/00015555-2495","article-title":"Imiquimod-induced psoriatic erythroderma treated with infliximab","volume":"97","author":"Tsutsumi","year":"2017","journal-title":"Acta Derm Venereol"},{"key":"2025052303173014900_llae527-B4","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1111\/1346-8138.13821","article-title":"Increased number of mast cells in the dermis in actinic keratosis lesions effectively treated with imiquimod","volume":"44","author":"Oyama","year":"2017","journal-title":"J Dermatol"},{"key":"2025052303173014900_llae527-B5","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1084\/jem.20130351","article-title":"A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis","volume":"210","author":"Salimi","year":"2013","journal-title":"J Exp Med"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ced\/advance-article-pdf\/doi\/10.1093\/ced\/llae527\/60972595\/llae527.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/50\/6\/1221\/60972595\/llae527.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/50\/6\/1221\/60972595\/llae527.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T07:17:42Z","timestamp":1747984662000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/50\/6\/1221\/7918387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,6]]},"references-count":5,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,12,6]]},"published-print":{"date-parts":[[2025,5,23]]}},"URL":"https:\/\/doi.org\/10.1093\/ced\/llae527","relation":{},"ISSN":["0307-6938","1365-2230"],"issn-type":[{"value":"0307-6938","type":"print"},{"value":"1365-2230","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,6]]},"published":{"date-parts":[[2024,12,6]]}}}