{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:19:50Z","timestamp":1785417590648,"version":"3.56.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T00:00:00Z","timestamp":1736985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Pilonidal sinus disease (PSD) is a chronic, debilitating condition predominantly affecting young men. Laser hair depilation is an established adjunct to surgical treatment for PSD. It can lead to reduced rates of recurrence and postsurgical interventions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To assess the outcome of laser hair depilation therapy on disease progression in patients with PSD at the Birmingham Skin Regional Laser Centre.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patient demographics, PSD clinical stage, laser type, number of laser sessions, surgical intervention and treatment outcomes were extracted from electronic medical records of patients (n = 97) referred for laser hair depilation between 2017 and 2023. Statistical analysis was performed using Microsoft Excel and R. Treatment outcomes were categorized as improvement (healed, improved) or no improvement of underlying PSD. Disease severity was classified using the method of Guner et al. (BMC Surg 2016; 16:18).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Most patients affected were male (77%). The median age was 22\u2005years (interquartile range 20\u201328). The median number of laser hair removal sessions was 8 (interquartile range 5.5\u201310). The number of laser hair removal sessions was the only predictive factor for symptom resolution (P &amp;lt; 0.001). Neither surgical intervention nor the type of surgery (incision, excision, modified flap, or endoscopic surgical intervention) showed a significant association with improvement in PSD (P = 0.47 and P = 0.65, respectively). In the subgroup of patients who did not undergo surgery (n = 32, 33%), 25 patients (78%) had improvement or healing in their PSD. There were no statistically significant associations between age, type of laser, disease severity and benefit from laser hair removal. No complications were reported and there was only one case of recurrence.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Laser hair depilation is a safe and effective postoperative adjunct treatment for treating sacrococcygeal PSD. For early-stage disease it may offer curative treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/ced\/llaf035","type":"journal-article","created":{"date-parts":[[2025,1,16]],"date-time":"2025-01-16T07:23:10Z","timestamp":1737012190000},"page":"1132-1137","source":"Crossref","is-referenced-by-count":4,"title":["Laser hair depilation therapy for pilonidal sinus disease: a\u00a05-year, retrospective experience in a university teaching hospital in the UK, 2017\u20132023"],"prefix":"10.1093","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5054-1225","authenticated-orcid":false,"given":"Kashini","family":"Andrew","sequence":"first","affiliation":[{"name":"Birmingham Skin Centre, Sandwell and West Birmingham Hospitals NHS Trust , Birmingham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Dyson","sequence":"additional","affiliation":[{"name":"Birmingham Skin Centre, Sandwell and West Birmingham Hospitals NHS Trust , Birmingham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pui Chi","family":"Lee","sequence":"additional","affiliation":[{"name":"Birmingham Skin Centre, Sandwell and West Birmingham Hospitals NHS Trust , Birmingham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooja","family":"Sonigra","sequence":"additional","affiliation":[{"name":"Birmingham Skin Centre, Sandwell and West Birmingham Hospitals NHS Trust , Birmingham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rona","family":"Applewaite","sequence":"additional","affiliation":[{"name":"Birmingham Skin Centre, Sandwell and West Birmingham Hospitals NHS Trust , Birmingham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danning","family":"Li","sequence":"additional","affiliation":[{"name":"Birmingham Skin Centre, Sandwell and West Birmingham Hospitals NHS Trust , Birmingham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Thomson","sequence":"additional","affiliation":[{"name":"Birmingham Skin Centre, Sandwell and West Birmingham Hospitals NHS Trust , Birmingham ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Nevill","sequence":"additional","affiliation":[{"name":"University of Wolverhampton Faculty of Education, Health and Wellbeing , Walsall ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,1,16]]},"reference":[{"key":"2025052303165639800_llaf035-B1","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/iwj.13042","article-title":"Management of sacrococcygeal pilonidal sinus disease","volume":"16","author":"Harries","year":"2019","journal-title":"Int Wound J"},{"key":"2025052303165639800_llaf035-B2","first-page":"719","article-title":"The role of collagen type I\/III ratio in the etiology of sacrococcygeal pilonidal","volume":"90","author":"Atay","year":"2022","journal-title":"Cir Cir"},{"key":"2025052303165639800_llaf035-B3","doi-asserted-by":"crossref","first-page":"13720","DOI":"10.1038\/s41598-020-70641-7","article-title":"Surgical procedures in the pilonidal sinus disease: a systematic review and network meta-analysis","volume":"10","author":"Bi","year":"2020","journal-title":"Sci Rep"},{"key":"2025052303165639800_llaf035-B4","doi-asserted-by":"crossref","first-page":"161934","DOI":"10.1016\/j.jpedsurg.2024.161934","article-title":"Platelet-rich plasma as an adjuvant therapy to crystallized phenol in the treatment of pediatric pilonidal sinus disease: a prospective randomized controlled trial","volume":"60","author":"Azizoglu","year":"2024","journal-title":"J Pediatr Surg"},{"key":"2025052303165639800_llaf035-B5","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s00383-020-04798-7","article-title":"Crystallized phenol for treatment of pilonidal sinus disease in children: a comparative clinical study","volume":"37","author":"Arslan","year":"2021","journal-title":"Pediatr Surg Int"},{"key":"2025052303165639800_llaf035-B6","first-page":"297","article-title":"Comparison of the effectiveness of laser and crystallized phenol in the treatment of sacrococcygeal pilonidal sinus","volume":"91","author":"Ta\u015fkin","year":"2023","journal-title":"Cir Cir"},{"key":"2025052303165639800_llaf035-B7","doi-asserted-by":"crossref","first-page":"179","DOI":"10.5144\/0256-4947.2021.179","article-title":"Pilonidal sinus disease recurrence at a tertiary care center in Riyadh","volume":"41","author":"Albabtain","year":"2021","journal-title":"Ann Saudi Med"},{"key":"2025052303165639800_llaf035-B8","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12893-016-0134-5","article-title":"A proposed staging system for chronic symptomatic pilonidal sinus disease and results in patients treated with stage-based approach","volume":"16","author":"Guner","year":"2016","journal-title":"BMC Surg"},{"key":"2025052303165639800_llaf035-B9","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1308\/rcsann.2020.0069","article-title":"Laser depilation as adjuvant therapy in prevention of recurrence of pilonidal sinus disease: initial experience of a district general hospital in the UK","volume":"102","author":"Liyanage","year":"2020","journal-title":"Ann R Coll Surg Engl"},{"key":"2025052303165639800_llaf035-B10","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.amsu.2020.07.050","article-title":"Pilonidal sinus disease: review of current practice and prospects for endoscopic treatment","volume":"57","author":"Mahmood","year":"2020","journal-title":"Ann Med Surg (Lond)"},{"key":"2025052303165639800_llaf035-B11","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1080\/14764172.2019.1605449","article-title":"The \u2018in\u2019s and outs\u2019 of laser hair removal: a mini review","volume":"21","author":"Thomas","year":"2019","journal-title":"J Cosmet Laser Ther"},{"key":"2025052303165639800_llaf035-B12","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1007\/s10151-023-02870-7","article-title":"Non-excisional techniques for the treatment of intergluteal pilonidal sinus disease: a systematic review","volume":"27","author":"Huurman","year":"2023","journal-title":"Tech Coloproctol"},{"key":"2025052303165639800_llaf035-B13","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/j.jss.2018.06.071","article-title":"Recurrence of pilonidal disease: our best is not good enough","volume":"232","author":"Halleran","year":"2018","journal-title":"J Surg Res"}],"container-title":["Clinical and Experimental 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