{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T17:10:30Z","timestamp":1754154630781,"version":"3.41.2"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T00:00:00Z","timestamp":1748908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Graft-versus-host disease (GVHD) is a common immune complication of haematopoietic stem cell transplantation (HSCT). GVHD is classified as acute or chronic, depending on the clinical characteristics. In acute cutaneous GVHD, the most common feature is a maculopapular rash. Some less frequently occurring clinical features have also been described, such as acquired ichthyosis, pityriasis rubra pilaris type II and eczema craquel\u00e9. Symmetrical intertriginous drug-related flexural exanthema (SDRIFE) is, on the other hand, a cutaneous reaction to medications characterized by symmetrical involvement of the flexion areas, which occurs in the absence of systemic involvement. We describe five paediatric patients with skinfold involvement after HSCT, mimicking SDRIFE. SDRIFE-like presentation, although rare, should be considered as a cutaneous manifestation of acute cutaneous GVHD in the context of patients post-HSCT.<\/jats:p>","DOI":"10.1093\/ced\/llaf071","type":"journal-article","created":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T12:16:38Z","timestamp":1748952998000},"page":"1628-1632","source":"Crossref","is-referenced-by-count":0,"title":["Symmetrical intertriginous drug-related flexural exanthema-like presentation in paediatric patients following bone marrow transplant: think graft-versus-host disease"],"prefix":"10.1093","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1647-2419","authenticated-orcid":false,"given":"Isabel","family":"Araiza-Atanacio","sequence":"first","affiliation":[{"name":"Dermatology Department, Instituto Nacional de Pediatr\u00eda , Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luz","family":"Orozco-Covarrubias","sequence":"additional","affiliation":[{"name":"Dermatology Department, Instituto Nacional de Pediatr\u00eda , Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marimar","family":"S\u00e1ez-de-Ocariz","sequence":"additional","affiliation":[{"name":"Dermatology Department, Instituto Nacional de Pediatr\u00eda , Mexico City ,","place":["Mexico"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,6,3]]},"reference":[{"key":"2025072412174254000_llaf071-B1","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/ijd.13381","article-title":"Cutaneous manifestations of graft-versus-host disease: role of the dermatologist","volume":"56","author":"Kavand","year":"2017","journal-title":"Int J Dermatol"},{"key":"2025072412174254000_llaf071-B2","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/s41572-023-00438-1","article-title":"Acute graft-versus-host disease","volume":"9","author":"Malard","year":"2023","journal-title":"Nat Rev Dis Primers"},{"key":"2025072412174254000_llaf071-B3","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s40257-017-0306-9","article-title":"Cutaneous graft-versus-host disease: diagnosis and treatment","volume":"19","author":"Strong Rodrigues","year":"2018","journal-title":"Am J Clin Dermatol"},{"key":"2025072412174254000_llaf071-B4","first-page":"100","article-title":"Pediatric cutaneous graft versus host disease: a review","volume":"13","author":"Shi","year":"2017","journal-title":"Curr Pediatr Rev"},{"key":"2025072412174254000_llaf071-B5","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1111\/cup.13836","article-title":"Eczematous graft-vs-host disease: a report of three cases and review of the literature","volume":"47","author":"Chan","year":"2020","journal-title":"J Cutan Pathol"},{"key":"2025072412174254000_llaf071-B6","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.medcli.2018.07.012","article-title":"Graft-versus-host disease","volume":"152","author":"Moreno","year":"2019","journal-title":"Med Clin (Barc)"},{"key":"2025072412174254000_llaf071-B7","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1111\/petr.12721","article-title":"Graft-versus-host disease in paediatric solid organ transplantation: a review of the literature","volume":"20","author":"Green","year":"2016","journal-title":"Pediatr Transplant"},{"key":"2025072412174254000_llaf071-B8","doi-asserted-by":"publisher","DOI":"10.5070\/D329461905","article-title":"Lenalidomide-induced symmetrical drug-related intertriginous and flexural exanthema","volume":"29","author":"Patel","year":"2023","journal-title":"Dermatol Online J"},{"key":"2025072412174254000_llaf071-B9","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1111\/cup.14090","article-title":"Symmetric drug-related intertriginous and flexural exanthema: clinicopathologic study of 19 cases and review of literature","volume":"48","author":"Schuler","year":"2021","journal-title":"J Cutan Pathol"},{"key":"2025072412174254000_llaf071-B10","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.jaad.2008.05.018","article-title":"Toxic erythema of chemotherapy: a useful clinical term","volume":"59","author":"Bolognia","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"2025072412174254000_llaf071-B11","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s40272-013-0039-z","article-title":"Cutaneous drug reactions in children: an update","volume":"15","author":"Heelan","year":"2013","journal-title":"Paediatr Drugs"},{"key":"2025072412174254000_llaf071-B12","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.jaad.2014.12.022","article-title":"Atypical manifestations of graft-versus-host disease","volume":"72","author":"Cornejo","year":"2015","journal-title":"J Am Acad Dermatol"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ced\/advance-article-pdf\/doi\/10.1093\/ced\/llaf071\/63427636\/llaf071.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/50\/8\/1628\/63427636\/llaf071.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/50\/8\/1628\/63427636\/llaf071.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T16:17:51Z","timestamp":1753373871000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/50\/8\/1628\/8155960"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,3]]},"references-count":12,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,6,3]]},"published-print":{"date-parts":[[2025,7,24]]}},"URL":"https:\/\/doi.org\/10.1093\/ced\/llaf071","relation":{},"ISSN":["0307-6938","1365-2230"],"issn-type":[{"type":"print","value":"0307-6938"},{"type":"electronic","value":"1365-2230"}],"subject":[],"published-other":{"date-parts":[[2025,8]]},"published":{"date-parts":[[2025,6,3]]}}}