{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T08:04:38Z","timestamp":1781078678534,"version":"3.54.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This study investigated the potential link between finasteride, commonly used for hair loss, and suicide attempts via self-poisoning. It was \u00admotivated by concerns over unanticipated psychological side-effects like suicidality identified in post-trial adverse event reports. We used data from multiple Danish health registries to assess male patients reported for suicidal intent poisoning. Each case was matched with 10 controls based on age, sex and residential municipality. We collected data on finasteride prescriptions up to 1\u2005year before the index date, which was the date of the suicide attempt for cases and the inclusion date for controls. The study included 3366 cases and 33 660 controls. Adjustments were made for diagnosed bipolar disorder and schizophrenia, as well as occupational status. The analysis showed no link between finasteride use and suicide attempt risk, with an unadjusted odds ratio of 1.03 (95% confidence interval 0.56\u20131.88) and an adjusted odds ratio of 0.88 (95% confidence interval 0.45\u20131.71).<\/jats:p>","DOI":"10.1093\/ced\/llaf268","type":"journal-article","created":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T13:08:12Z","timestamp":1751029692000},"page":"2037-2039","source":"Crossref","is-referenced-by-count":1,"title":["Finasteride use and suicide attempts through self-poisoning: a case\u2013control study"],"prefix":"10.1093","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6130-875X","authenticated-orcid":false,"given":"Ida M","family":"Heerfordt","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacology, Copenhagen University Hospital \u2013 Bispebjerg and Frederiksberg , Copenhagen ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika Magdalena","family":"Rhomberg-Kauert","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology, Copenhagen University Hospital \u2013 Bispebjerg and Frederiksberg , Copenhagen ,","place":["Denmark"]},{"name":"Medical University of Vienna , Vienna ,","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim Peder","family":"Dalhoff","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology, Copenhagen University Hospital \u2013 Bispebjerg and Frederiksberg , Copenhagen ,","place":["Denmark"]},{"name":"Department of Clinical Medicine, University of Copenhagen , Copenhagen ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"Tulstrup","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology, Copenhagen University Hospital \u2013 Bispebjerg and Frederiksberg , Copenhagen ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Horwitz","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacology, Copenhagen University Hospital \u2013 Bispebjerg and Frederiksberg , Copenhagen ,","place":["Denmark"]},{"name":"Department of Clinical Medicine, University of Copenhagen , Copenhagen ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"2025092509025614300_llaf268-B1","doi-asserted-by":"crossref","first-page":"e2248135","DOI":"10.1001\/jamanetworkopen.2022.48135","article-title":"Association of 5\u03b1-reductase inhibitors with dementia, depression, and suicide","volume":"5","author":"Garcia-Argibay","year":"2022","journal-title":"JAMA Netw Open"},{"key":"2025092509025614300_llaf268-B2","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1001\/jamadermatol.2020.3385","article-title":"Investigation of suicidality and psychological adverse events in patients treated with finasteride","volume":"157","author":"Nguyen","year":"2021","journal-title":"JAMA Dermatol"},{"issue":"Suppl. 9","key":"2025092509025614300_llaf268-B3","first-page":"S31","article-title":"Comparison of clinical trials with finasteride and dutasteride","volume":"6","author":"Nickel","year":"2004","journal-title":"Rev Urol"},{"key":"2025092509025614300_llaf268-B4","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.euros.2023.04.009","article-title":"US Food and Drug Administration warning regarding finasteride and suicidal ideation: what should urologists know?","volume":"52","author":"Al Saffar","year":"2023","journal-title":"Eur Urol Open Sci"},{"key":"2025092509025614300_llaf268-B5","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.jaad.2024.10.043","article-title":"No association between acne treatment with retinoids and suicide attempts in adolescents: a case\u2013control study","volume":"92","author":"Heerfordt","year":"2025","journal-title":"J Am Acad Dermatol"},{"key":"2025092509025614300_llaf268-B6","first-page":"306","article-title":"Prevention of suicide and attempted suicide in Denmark. Epidemiological studies of suicide and intervention studies in selected risk groups","volume":"54","author":"Nordentoft","year":"2007","journal-title":"Dan Med Bull"},{"key":"2025092509025614300_llaf268-B7","doi-asserted-by":"crossref","first-page":"563","DOI":"10.2147\/CLEP.S179083","article-title":"The Danish health care system and epidemiological research: from health care contacts to database records","volume":"11","author":"Schmidt","year":"2019","journal-title":"Clin Epidemiol"},{"key":"2025092509025614300_llaf268-B8"},{"key":"2025092509025614300_llaf268-B9","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1097\/EDE.0b013e3181a819a1","article-title":"Overadjustment bias and unnecessary adjustment in epidemiologic studies","volume":"20","author":"Schisterman","year":"2009","journal-title":"Epidemiology"},{"key":"2025092509025614300_llaf268-B10","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3390\/pharmacy12010033","article-title":"New adverse drug reaction signals from 2017 to 2021 \u2013 genuine alerts or false alarms?","volume":"12","author":"Loke","year":"2024","journal-title":"Pharmacy (Basel)"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ced\/advance-article-pdf\/doi\/10.1093\/ced\/llaf268\/63523332\/llaf268.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/50\/10\/2037\/63523332\/llaf268.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/50\/10\/2037\/63523332\/llaf268.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T13:03:03Z","timestamp":1758805383000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/50\/10\/2037\/8168821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,18]]},"references-count":10,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2025,6,18]]},"published-print":{"date-parts":[[2025,9,25]]}},"URL":"https:\/\/doi.org\/10.1093\/ced\/llaf268","relation":{},"ISSN":["0307-6938","1365-2230"],"issn-type":[{"value":"0307-6938","type":"print"},{"value":"1365-2230","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,10]]},"published":{"date-parts":[[2025,6,18]]}}}