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The relevance of this work lies in the possibility of reshaping the understanding of the interplay of germline and somatic mutations in cutaneous conditions.<\/jats:p>","DOI":"10.1093\/ced\/llaf273","type":"journal-article","created":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T07:56:21Z","timestamp":1750319781000},"page":"2347-2350","source":"Crossref","is-referenced-by-count":0,"title":["Early-onset extensive seborrhoeic keratoses in the spectrum of familial acanthosis nigricans"],"prefix":"10.1093","volume":"50","author":[{"given":"David","family":"Pesqu\u00e9","sequence":"first","affiliation":[{"name":"Department of Dermatology, Hospital del Mar Research Institute, Barcelona ,","place":["Spain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"Bellosillo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital del Mar, Hospital del Mar Research Institute , Barcelona ,","place":["Spain"]},{"name":"Departament of 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