{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T17:47:34Z","timestamp":1764092854712,"version":"3.45.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T00:00:00Z","timestamp":1752537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pyogenic granuloma is a benign vascular lesion. The differential diagnosis encompasses both malignant and benign conditions. While several modalities are available for its management, only surgical options enable a histopathological diagnosis, which is crucial to rule out clinical mimickers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To examine paediatric patients with pyogenicgranuloma-like Spitz naevus and emphasize the importance of tissue sampling for diagnostic accuracy and optimal care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective single-centre study of paediatric patients with lesions clinically diagnosed as pyogenic granuloma ultimately diagnosed as Spitz naevus following a histopathological evaluation between January 2018 and December 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 84 paediatric patients with clinically suspected pyogenic granuloma who underwent biopsy, 6 (7.1%) were diagnosed with Spitz naevus. All lesions had involved surgical margins requiring re-excision, which achieved clear margins with no recurrences during an average follow-up of 27.5\u2005months. The mean age of the patients at onset was 2\u2005years 4\u2005months. Lesions were evenly distributed between the face and extremities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The broad differential diagnosis of pyogenic granuloma highlights the risk of misdiagnosis when solely relying on a clinical diagnosis. Although nonsurgical treatments are convenient, the high clinicopathological discrepancy rate further underscores the need for histopathological confirmation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ced\/llaf298","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T14:16:59Z","timestamp":1752502619000},"page":"2392-2396","source":"Crossref","is-referenced-by-count":0,"title":["Pyogenic granuloma-like Spitz naevus in paediatric patients: a case series"],"prefix":"10.1093","volume":"50","author":[{"given":"Asaf","family":"Olshinka","sequence":"first","affiliation":[{"name":"Gray Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]},{"name":"Plastic Surgery and Burns Unit, Schneider Children\u2019s Medical Center of Israel , Petah Tikva ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4865-6027","authenticated-orcid":false,"given":"Gaia","family":"Harris Rimon","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moshe","family":"Lapidoth","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]},{"name":"Laser Unit, Division of Dermatology, Rabin Medical Center , Petah Tikva ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Mimouni","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]},{"name":"Laser Unit, Division of Dermatology, Rabin Medical Center , Petah Tikva ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Israel","family":"Ingber","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]},{"name":"Laser Unit, Division of Dermatology, Rabin Medical Center , Petah Tikva ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Khalil","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]},{"name":"Department of Anesthesiology, Rabin Medical Center , Petah Tikva ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Didkovsky","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]},{"name":"Institute of Pathology, Rabin Medical Center , Petah Tikva ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Assi","family":"Levi","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]},{"name":"Laser Unit, Division of Dermatology, Rabin Medical Center , Petah Tikva ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2481-4714","authenticated-orcid":false,"given":"Yehonatan","family":"Noyman","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medicine, Tel Aviv University , Tel Aviv ,","place":["Israel"]},{"name":"Laser Unit, Division of Dermatology, Rabin Medical Center , Petah Tikva ,","place":["Israel"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,7,15]]},"reference":[{"key":"2025112512423318200_llaf298-B1","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/S0190-9622(97)70065-3","article-title":"Cutaneous vascular proliferation. 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