{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T15:19:44Z","timestamp":1778253584184,"version":"3.51.4"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T00:00:00Z","timestamp":1757548800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pemphigus foliaceus (PF) is an uncommon autoimmune disease characterized by superficial blistering and erosions of the skin. The literature on PF globally is limited. Understanding clinicodemographic heterogeneity in PF is crucial for improving outcomes for affected individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To study the clinicodemographic characteristics and treatment outcomes of patients with PF in north India.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective study was conducted of patients with PF registered at the authors\u2019 clinic at the Postgraduate Institute of Medical Education and Research in Chandigarh, north India, between November 2013 and June 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 103 patients with PF were included in the study. The mean (SD) age at disease onset was 40.4 (15.7) years, with a male-to-female ratio of 1.7 : 1. The median duration of disease at presentation was 18\u2005months (range 1\u2013240). The most commonly prescribed treatment was topical corticosteroids (n = 98\/103; 95.1%) or oral corticosteroids (n = 97\/103; 94.2%), either alone or in combination with steroid-sparing adjuvants. Rituximab was the commonest adjuvant and was used in 43.7% (n = 45\/103) of patients. Overall, 75.7% (n = 78\/103) of patients achieved clinical remission on minimal treatment (CRmin) in a mean of 6.5 (3.9) months. Clinical remission off treatment (CRoff) was achieved in 10.4 (6.0) months in 67.0% (n = 69\/103) of patients. Among patients in the rituximab group, CRmin was achieved in 91.1% (n = 41\/45) of patients in 6.3 (4.6) months and CRoff was achieved in 82.2% (n = 37\/45) of patients in 9.0 (5.6) months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In the present study PF was more common in men aged between 40 and 60\u2005years. Corticosteroids (topical\/systemic) formed the mainstay of treatment, with rituximab being the most commonly used steroid-sparing adjuvant. Prospective studies in a larger cohort are required for a better understanding of this disease in nonendemic locations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ced\/llaf408","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T11:58:53Z","timestamp":1757505533000},"page":"840-845","source":"Crossref","is-referenced-by-count":1,"title":["Clinicodemographic characteristics of pemphigus foliaceus: retrospective analysis of clinic-based data for\u00a0103 patients in a nonendemic location"],"prefix":"10.1093","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8682-2598","authenticated-orcid":false,"given":"Dipankar","family":"De","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research , Chandigarh ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9495-7502","authenticated-orcid":false,"given":"Apoorva","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research , Chandigarh ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinod","family":"Hanumanthu","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research , Chandigarh ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5414-2598","authenticated-orcid":false,"given":"Debajyoti","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Postgraduate Institute of Medical Education and Research , Chandigarh ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uma\u00a0Nahar","family":"Saikia","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Postgraduate Institute of Medical Education and Research , Chandigarh ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biman","family":"Saikia","sequence":"additional","affiliation":[{"name":"Department of Immunopathology, Postgraduate Institute of Medical Education and Research , Chandigarh ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4320-3193","authenticated-orcid":false,"given":"Rahul","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research , Chandigarh ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1486-7161","authenticated-orcid":false,"given":"Sanjeev","family":"Handa","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research , Chandigarh ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,9,11]]},"reference":[{"key":"2026042410413509500_llaf408-B1","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1111\/ced.14041","article-title":"Pemphigus vulgaris and pemphigus foliaceus: an overview of the clinical presentation, investigations and management","volume":"44","author":"Melchionda","year":"2019","journal-title":"Clin Exp 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