{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T15:59:30Z","timestamp":1777046370020,"version":"3.51.4"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Nigeria continues to report over 2000 new leprosy cases annually. This retrospective study reviewed leprosy case records from 2006 to 2023 at a teaching hospital (TH) and a leprosy treatment referral centre (LTRC) in Lagos, Nigeria. Demographic, clinical and treatment data were analysed and challenges highlighted. At the TH, 96 patients with leprosy were seen. The median age was 34.6\u2005years (range 11\u201379); 61 (64%) were male; and 75% had multibacillary disease. At the LTRC, 354 patients were seen. The median age was 39.8\u2005years (range 7\u201385); 230 (65%) were male; and 349 (98.6%) had multibacillary disease. Late presentation was common in both centres. Most patients received multidrug therapy at the LTRC, but of 450 patient records overall, 52 defaulted from care (19 from the TH; 33 from the LTRC). Between 2017 and 2023, 25% of patients (37 of 149), including 2.7% aged &amp;lt; 15\u2005years, presented with grade 2 disability. Leprosy cases have declined in Lagos, but delayed presentation, inadequate frontline diagnostic capacity and weak surveillance systems contribute to sustained morbidity. Strengthening health worker knowledge and surveillance in an integrated approach is essential for leprosy control.<\/jats:p>\n                  <jats:p>Teaser text<\/jats:p>","DOI":"10.1093\/ced\/llaf442","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T12:05:10Z","timestamp":1759925110000},"page":"876-880","source":"Crossref","is-referenced-by-count":0,"title":["Demographic and clinical profile of patients with leprosy in Lagos, Nigeria: a 17-year retrospective study"],"prefix":"10.1093","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8379-8868","authenticated-orcid":false,"given":"Olufolakemi","family":"Cole-Adeife","sequence":"first","affiliation":[{"name":"Dermatology Unit, Department of Medicine, Lagos State University Teaching Hospital , Lagos ,","place":["Nigeria"]},{"name":"Department of Medicine, Lagos State University College of Medicine , Lagos ,","place":["Nigeria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gbolahan","family":"Dairo","sequence":"additional","affiliation":[{"name":"Damien Foundation Belgium (DFB) , Ibadan ,","place":["Nigeria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luther","family":"Agaga","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medicine, Lagos State University Teaching Hospital , Lagos ,","place":["Nigeria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances","family":"Ajose","sequence":"additional","affiliation":[{"name":"Dermatology Unit, Department of Medicine, Lagos State University Teaching Hospital , Lagos ,","place":["Nigeria"]},{"name":"Department of Medicine, Lagos State University College of Medicine , Lagos ,","place":["Nigeria"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,10,9]]},"reference":[{"key":"2026042410415493100_llaf442-B1","author":"World Health Organization. Fact sheets","journal-title":"Leprosy"},{"key":"2026042410415493100_llaf442-B2","article-title":"Towards zero leprosy. Global leprosy (Hansen\u2019s disease) strategy 2021\u20132030","author":"World Health Organization","year":"15  2021"},{"key":"2026042410415493100_llaf442-B3","first-page":"e44767","article-title":"Leprosy classification, clinical features, epidemiology, and host immunological responses: failure of eradication in 2023","volume":"15","author":"Alrehaili","year":"2023","journal-title":"Cureus"},{"key":"2026042410415493100_llaf442-B4","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1093\/trstmh\/trae050","article-title":"Investigation of community knowledge, attitudes and stigma towards leprosy in Nigeria: a mixed-methods study","volume":"118","author":"Murphy-Okpala","year":"2024","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"2026042410415493100_llaf442-B5","author":"World Health Organization"},{"key":"2026042410415493100_llaf442-B6","doi-asserted-by":"crossref","first-page":"8652062","DOI":"10.1155\/2022\/8652062","article-title":"Leprosy: a review of epidemiology, clinical diagnosis, and management","volume":"2022","author":"Chen","year":"2022","journal-title":"J Trop Med"},{"key":"2026042410415493100_llaf442-B7","doi-asserted-by":"crossref","first-page":"279","DOI":"10.47276\/lr.74.3.279","article-title":"Leprosy: From the clinics of a tertiary institution in South Eastern Nigeria","volume":"74","author":"Nnoruka","year":"2003","journal-title":"Lepr Rev"},{"key":"2026042410415493100_llaf442-B8","doi-asserted-by":"crossref","first-page":"229","DOI":"10.47276\/lr.84.3.229","article-title":"Leprosy situation in Nigeria","volume":"84","author":"Udo","year":"2013","journal-title":"Lepr Rev"},{"key":"2026042410415493100_llaf442-B9","doi-asserted-by":"crossref","first-page":"317","DOI":"10.47276\/lr.94.4.317","article-title":"Leprosy capacity in health facilities and among health workers: a baseline survey in Nigeria","volume":"94","author":"Dahiru","year":"2023","journal-title":"Lepr Rev"},{"key":"2026042410415493100_llaf442-B10","doi-asserted-by":"crossref","first-page":"e0011357","DOI":"10.1371\/journal.pntd.0011357","article-title":"A global call for action to tackle skin-related neglected tropical diseases (skin NTDs) through integration: an ambitious step change","volume":"17","author":"Yotsu","year":"2023","journal-title":"PLOS Negl Trop Dis"}],"container-title":["Clinical and Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/ced\/advance-article-pdf\/doi\/10.1093\/ced\/llaf442\/64581520\/llaf442.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/51\/5\/876\/64581520\/llaf442.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/ced\/article-pdf\/51\/5\/876\/64581520\/llaf442.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:41:59Z","timestamp":1777041719000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/ced\/article\/51\/5\/876\/8280088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,9]]},"references-count":10,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2025,10,9]]},"published-print":{"date-parts":[[2026,4,24]]}},"URL":"https:\/\/doi.org\/10.1093\/ced\/llaf442","relation":{},"ISSN":["0307-6938","1365-2230"],"issn-type":[{"value":"0307-6938","type":"print"},{"value":"1365-2230","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,5]]},"published":{"date-parts":[[2025,10,9]]}}}