{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:23:25Z","timestamp":1790810605664,"version":"4.1.0"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014653","name":"NIHR Manchester Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR203308"],"award-info":[{"award-number":["NIHR203308"]}],"id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,24]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Fibrosing alopecia in a pattern distribution (FAPD) is a lymphocytic primary cicatricial alopecia first described in 2000. However, to date, the FAPD literature remains sparse.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To identify clinicopathological features and treatment outcomes of FAPD in a large multicentre cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients who had biopsy-proven FAPD were selected from nine specialist hair clinics and were reviewed retrospectively to evaluate the clinical pattern of hair loss, trichoscopic and histopathological features, and response to treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 110 patients, with a mean age of onset of 52.5 (SD 14.8) years, 94 (85.5%) were women. The most common trichoscopic findings were loss of follicular ostia (97.2%, 103\/106) and anisotrichia (97%, 84\/87). Histopathological examination revealed perifollicular lymphocytic infiltration in 96.1% (99\/103) and concentric lamellar fibrosis in 97% (92\/95). After a median duration of treatment of 24 [interquartile range (IQR) 13\u201350] months, there was stabilization in hair density [median Sinclair grade 3.0 (IQR 3.0\u20134.0) pretreatment vs. 3.0 (IQR 2.0\u20134.0) post-treatment, P = 0.62]. Out of the 42 patients who received treatment for \u2265 12\u2005months, 23 achieved stabilization and 16 demonstrated improvement in hair density.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Limitations of the study include its retrospective design and disparate treatments. FAPD may be prone to misdiagnosis because of overlapping clinicopathological features with androgenetic alopecia. A combination of anti-inflammatory (for example, topical corticosteroids) and hair growth-promoting agents (for example, topical or low-dose oral minoxidil) can stabilize the condition or even promote hair regrowth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/ced\/llaf444","type":"journal-article","created":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T12:04:57Z","timestamp":1759925097000},"page":"411-417","source":"Crossref","is-referenced-by-count":3,"title":["Clinicopathological features and treatment outcomes of fibrosing alopecia in a pattern distribution: a multicentre cohort study"],"prefix":"10.1093","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6826-131X","authenticated-orcid":false,"given":"Gia Toan","family":"Tang","sequence":"first","affiliation":[{"name":"Sinclair Dermatology , East Melbourne, VIC ,","place":["Australia"]},{"name":"The University of Melbourne , Parkville, VIC 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